Effect of MM-141 on gemcitabine and nab-paclitaxel potentiation in preclinical models of pancreatic cancer through induction of IGF-1R and ErbB3 degradation
Pace, Emily, Adams, Sharlene, Camblin, Adam, Curley, Michael, Rimkunas, Victoria, Nie, Lin, Iadevaia, Sergio, Tan, Gege, Baum, Jason, Czibere, Akos Gabor, Lugovskoy, Alexey
Published in Journal of clinical oncology (20.01.2015)
Published in Journal of clinical oncology (20.01.2015)
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Journal Article
Abstract CT237: Preclinical characterization and first-in-human study of MM-141, a dual antibody inhibitor of IGF-1R and ErbB3
Lugovskoy, Alexey A., Curley, Michel, Baum, Jason, Adams, Sharlene, Iadevaia, Sergio, Rimkunas, Victoria, Camblin, Adam, Nie, Lin, Tan, Gege, Johnson, Bryan, Mathews, Sara, Horgan, Kerry, Louis, Chrystal U., Czibere, Akos G., Arnedos, Monica, Soria, Jean-Charles, Bahleda, Rastilav, Shields, Anthony, LoRusso, Patricia M., Saleh, Mansoor, Isakoff, Steven J.
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Abstract 2077A: MM141, a novel bispecific antibody co-inhibitor of IGF-1R and ErbB3, inhibits the proliferation of melanoma cells
Von Euw, Erika M., Pace, Emily, Covarrubias, Karina, Jairam, Abhi, Chai, Diana, Konkankit, Veerauo, Gong, Ke-Wei, Johnson, Bryan, Schoeberl, Birgit, Lugovskoy, Alexey, Richard, Finn, Slamon, Dennis
Published in Cancer research (Chicago, Ill.) (15.04.2013)
Published in Cancer research (Chicago, Ill.) (15.04.2013)
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글리칸-상호작용 화합물 및 사용방법
EAVARONE DAVID A, PRENDERGAST JILLIAN M, LUGOVSKOY ALEXEY ALEXANDROVICH, BEHRENS JEFFREY, DRANSFIELD DANIEL T
Year of Publication 03.08.2018
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Year of Publication 03.08.2018
Patent
Abstract 2719: MM-141, a novel bispecific antibody co-targeting IGF-1R and ErbB3, blocks ligand-induced signaling and demonstrates antitumor activity
Baum, Jason, Johnson, Bryan, Adams, Sharlene, Tang, Jian, Kohli, Neeraj, Rennard, Rachel, Sundararajan, Pragalath, Xu, Lihui, Jiao, Yang, Schoeberl, Birgit, Nielsen, Ulrik, Fitzgerald, Jonathan, Lugovskoy, Alexey
Published in Cancer research (Chicago, Ill.) (15.04.2012)
Published in Cancer research (Chicago, Ill.) (15.04.2012)
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Journal Article
8th Annual European Antibody Congress 2012: November 27–28, 2012, Geneva, Switzerland
Beck, Alain, Carter, Paul J., Gerber, Hans-Peter, Lugovskoy, Alexey A., Wurch, Thierry, Junutula, Jagath R., Kontermann, Roland E, Mabry, Robert
Published in mAbs (01.05.2013)
Published in mAbs (01.05.2013)
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αvβ6 인테그린 억제제
HAHN KRISTOPHER NEIL, LIPPA BLAISE SCOTT, HARRISON BRYCE ALDEN, SVENSSON MATS AKE, GERASYUTO ALEKSEY LGOREVICH, LIN FU YANG, BURSAVICH MATTHEW GREGORY, KONZE KYLE DAVID, ROGERS BRUCE NELSEN, TROAST DAWN MARIE, LUGOVSKOY ALEXEY ALEXANDROVICH, BREWER MARK
Year of Publication 03.12.2019
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Year of Publication 03.12.2019
Patent
Abstract B205: Therapeutically targeting redundant, growth factor-induced prosurvival signaling with MM-141, a novel bispecific antibody targeting IGF-1R and ErbB3
Lugovskoy, Alexey, Johnson, Bryan, Baum, Jason, Adams, Sharlene, Tang, Jian, Kohli, Neeraj, Rennard, Rachel, Xu, Lihui, Jiao, Yang, Nilesen, Ulrik, Fitzgerald, Jonathan
Published in Molecular cancer therapeutics (12.11.2011)
Published in Molecular cancer therapeutics (12.11.2011)
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