Search Results - "LUDIVINE MOINE" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Molecular Basis of Valine-Citrulline-PABC Linker Instability in Site-Specific ADCs and Its Mitigation by Linker Design

Molecular Basis of Valine-Citrulline-PABC Linker Instability in Site-Specific ADCs and Its Mitigation by Linker Design

by Dorywalska, Magdalena, Dushin, Russell, Moine, Ludivine, Farias, Santiago E, Zhou, Dahui, Navaratnam, Thayalan, Lui, Victor, Hasa-Moreno, Adela, Casas, Meritxell Galindo, Tran, Thomas-Toan, Delaria, Kathy, Liu, Shu-Hui, Foletti, Davide, O'Donnell, Christopher J, Pons, Jaume, Shelton, David L, Rajpal, Arvind, Strop, Pavel
Published in Molecular cancer therapeutics (01.05.2016)

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Journal Article

Site-Dependent Degradation of a Non-Cleavable Auristatin-Based Linker-Payload in Rodent Plasma and Its Effect on ADC Efficacy

Site-Dependent Degradation of a Non-Cleavable Auristatin-Based Linker-Payload in Rodent Plasma and Its Effect on ADC Efficacy

by Dorywalska, Magdalena, Strop, Pavel, Melton-Witt, Jody A, Hasa-Moreno, Adela, Farias, Santiago E, Galindo Casas, Meritxell, Delaria, Kathy, Lui, Victor, Poulsen, Kris, Sutton, Janette, Bolton, Gary, Zhou, Dahui, Moine, Ludivine, Dushin, Russell, Tran, Thomas-Toan, Liu, Shu-Hui, Rickert, Mathias, Foletti, Davide, Shelton, David L, Pons, Jaume, Rajpal, Arvind
Published in PloS one (10.07.2015)

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Journal Article

Effect of Attachment Site on Stability of Cleavable Antibody Drug Conjugates

Effect of Attachment Site on Stability of Cleavable Antibody Drug Conjugates

by Dorywalska, Magdalena, Strop, Pavel, Melton-Witt, Jody A, Hasa-Moreno, Adela, Farias, Santiago E, Galindo Casas, Meritxell, Delaria, Kathy, Lui, Victor, Poulsen, Kris, Loo, Carole, Krimm, Stellanie, Bolton, Gary, Moine, Ludivine, Dushin, Russell, Tran, Thomas-Toan, Liu, Shu-Hui, Rickert, Mathias, Foletti, Davide, Shelton, David L, Pons, Jaume, Rajpal, Arvind
Published in Bioconjugate chemistry (15.04.2015)

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Journal Article

Identification and characterization of second-generation EZH2 inhibitors with extended residence times and improved biological activity

Identification and characterization of second-generation EZH2 inhibitors with extended residence times and improved biological activity

by Stuckey, Jacob I., Cantone, Nico R., Côté, Alexandre, Arora, Shilpi, Vivat, Valerie, Ramakrishnan, Ashwin, Mertz, Jennifer A., Khanna, Avinash, Brenneman, Jehrod, Gehling, Victor S., Moine, Ludivine, Sims, Robert J., Audia, James E., Trojer, Patrick, Levell, Julian R., Cummings, Richard T.
Published in The Journal of biological chemistry (01.01.2021)

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Journal Article

MODULATORS OF METHYL MODIFYING ENZYMES, AND COMPOSITIONS AND USES THEREOF

MODULATORS OF METHYL MODIFYING ENZYMES, AND COMPOSITIONS AND USES THEREOF

by ALEXANDRE COTE, LUDIVINE MOINE, JACOB I STUCKEY, VICTOR S GEHLING, AVINASH KHANNA
Year of Publication 13.06.2023

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Patent

STABILITY-MODULATING LINKERS FOR USE WITH ANTIBODY DRUG CONJUGATES

STABILITY-MODULATING LINKERS FOR USE WITH ANTIBODY DRUG CONJUGATES

by PAVEL STROP, LUDIVINE MOINE, MAGDALENA GRAZYNA DORYWALSKA, RUSSELL GEORGE DUSHIN
Year of Publication 13.05.2021

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Patent

Design, Synthesis, and Pharmacological Evaluation of Second Generation EZH2 Inhibitors with Long Residence Time

Design, Synthesis, and Pharmacological Evaluation of Second Generation EZH2 Inhibitors with Long Residence Time

by Khanna, Avinash, Cote, Alexandre, Arora, Shilpi, Moine, Ludivine, Gehling, Victor S., Brenneman, Jehrod, Cantone, Nico, Stuckey, Jacob, Apte, Shruti, Ramakrishnan, Ashwin, Bruderek, Kamil, Bradley, William D., Audia, James E., Cummings, Richard T., Sims, Robert J., Trojer, Patrick, Levell, Julian R.
Published in ACS medicinal chemistry letters (11.06.2020)

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Journal Article

Abstract LB565: Efficacy of a highly potent and selective KIT V654A inhibitor for treatment of imatinib resistant GIST

Abstract LB565: Efficacy of a highly potent and selective KIT V654A inhibitor for treatment of imatinib resistant GIST

by Grassian, Alexandra R., Kim, Joseph, Ahmad, Omar, Barvian, Kevin, Davis, Alison, Dineen, Tom, Hu, Wei, Job, Ebby, Moine, Ludivine, Newberry, Kate, Roche, Maria, Shorten, Doug, Choi, Yeon Sook, Wolenski, Francis, Bauer, Sebastian, Serrano, Cesar, Trent, Jonathan, George, Suzanne
Published in Cancer research (Chicago, Ill.) (15.06.2022)

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Journal Article

Discovery of a novel Kv7 channel opener as a treatment for epilepsy

Discovery of a novel Kv7 channel opener as a treatment for epilepsy

by Davoren, Jennifer E., Claffey, Michelle M., Snow, Sheri L., Reese, Matthew R., Arora, Gaurav, Butler, Christopher R., Boscoe, Brian P., Chenard, Lois, DeNinno, Shari L., Drozda, Susan E., Duplantier, Allen J., Moine, Ludivine, Rogers, Bruce N., Rong, SuoBao, Schuyten, Katherine, Wright, Ann S., Zhang, Lei, Serpa, Kevin A., Weber, Mark L., Stolyar, Polina, Whisman, Tammy L., Baker, Karen, Tse, Karen, Clark, Alan J., Rong, Haojing, Mather, Robert J., Lowe, John A.
Published in Bioorganic & medicinal chemistry letters (01.11.2015)

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Journal Article

STABILITY-MODULATING LINKER USED WITH ANTIBODY DRUG CONJUGATE

STABILITY-MODULATING LINKER USED WITH ANTIBODY DRUG CONJUGATE

by PAVEL STROP, LUDIVINE MOINE, MAGDALENA GRAZYNA DORYWALSKA, RUSSELL GEORGE DUSHIN
Year of Publication 11.04.2016

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Patent

HETEROARYL SULFONE-BASED CONJUGATION HANDLES, METHODS FOR THEIR PREPARATION, AND THEIR USE IN SYNTHESIZING ANTIBODY DRUG CONJUGATES

HETEROARYL SULFONE-BASED CONJUGATION HANDLES, METHODS FOR THEIR PREPARATION, AND THEIR USE IN SYNTHESIZING ANTIBODY DRUG CONJUGATES

by JOSEPH A ABRAMITE, DANIEL P UCCELLO, LAWRENCE N TUMEY, GARY FREDERICK FILZEN, JENNIFER YOUNG, ADAM MATTHEW GILBERT, LEE R ROBERTS, JEFFREY M CASAVANT, LUDIVINE MOINE, MARK EDWARD FLANAGAN, O'DONNELL CHRISTOPHER JOHN, CHE YE, JEREMY STARR, RUSSELL GEORGE DUSHIN
Year of Publication 12.04.2018

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Patent

Modulators of methyl modifying enzymes, compositions and uses thereof

Modulators of methyl modifying enzymes, compositions and uses thereof

by Côté, Alexandre, Moine, Ludivine, Khanna, Avinash
Year of Publication 05.03.2024

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Patent

Moduladores de enzimas modificadoras de metilo, composiciones y usos de los mismos

Moduladores de enzimas modificadoras de metilo, composiciones y usos de los mismos

by CÔTE, Alexandre, STUCKEY, Jacob, GEHLING, Victor, MOINE, Ludivine, KHANNA, Avinash
Year of Publication 22.10.2024

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Patent

MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF

MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF

by STUCKEY, Jacob, CÔTE, Alexandre, GEHLING, Victor, MOINE, Ludivine, KHANNA, Avinash
Year of Publication 28.09.2024

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Patent

MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF

MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF

by STUCKEY, Jacob, GEHLING, Victor, MOINE, Ludivine, CÔTÉ, Alexandre, KHANNA, Avinash
Year of Publication 10.07.2024

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Patent

MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF

MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF

by STUCKEY, Jacob, GEHLING, Victor, MOINE, Ludivine, CÔTÉ, Alexandre, KHANNA, Avinash
Year of Publication 13.06.2024

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Patent

MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF

MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF

by MOINE, Ludivine, CÔTÉ, Alexandre, KHANNA, Avinash
Year of Publication 20.07.2022

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Patent

MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF

MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF

by Côté, Alexandre, Moine, Ludivine, Khanna, Avinash
Year of Publication 08.07.2021

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Patent

MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF

MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF

by Gehling, Victor, S, Stuckey, Jacob, I, Côté, Alexandre, Moine, Ludivine, Khanna, Avinash
Year of Publication 13.09.2024

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Patent

MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF

MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF

by COTE Alexandre, STUCKEY Jacob I, KHANNA Avinash, GEHLING Victor S, MOINE Ludivine
Year of Publication 30.08.2024

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Patent