Automated microfluidic cell culture of stem cell derived dopaminergic neurons
Kane, Khalid I. W., Moreno, Edinson Lucumi, Hachi, Siham, Walter, Moriz, Jarazo, Javier, Oliveira, Miguel A. P., Hankemeier, Thomas, Vulto, Paul, Schwamborn, Jens C., Thoma, Martin, Fleming, Ronan M. T.
Published in Scientific reports (11.02.2019)
Published in Scientific reports (11.02.2019)
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Journal Article
Derivation of Human Midbrain-Specific Organoids from Neuroepithelial Stem Cells
Monzel, Anna S., Smits, Lisa M., Hemmer, Kathrin, Hachi, Siham, Moreno, Edinson Lucumi, van Wuellen, Thea, Jarazo, Javier, Walter, Jonas, Brüggemann, Inga, Boussaad, Ibrahim, Berger, Emanuel, Fleming, Ronan M.T., Bolognin, Silvia, Schwamborn, Jens C.
Published in Stem cell reports (09.05.2017)
Published in Stem cell reports (09.05.2017)
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Journal Article
LC–MS/MS analysis of the central energy and carbon metabolites in biological samples following derivatization by dimethylaminophenacyl bromide
Willacey, Cornelius C.W., Naaktgeboren, Martijn, Lucumi Moreno, Edinson, Wegrzyn, Agnieszka B., van der Es, Daan, Karu, Naama, Fleming, Ronan M.T., Harms, Amy C., Hankemeier, Thomas
Published in Journal of Chromatography A (20.12.2019)
Published in Journal of Chromatography A (20.12.2019)
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Journal Article
3D Cultures of Parkinson's Disease‐Specific Dopaminergic Neurons for High Content Phenotyping and Drug Testing
Bolognin, Silvia, Fossépré, Marie, Qing, Xiaobing, Jarazo, Javier, Ščančar, Janez, Moreno, Edinson Lucumi, Nickels, Sarah L., Wasner, Kobi, Ouzren, Nassima, Walter, Jonas, Grünewald, Anne, Glaab, Enrico, Salamanca, Luis, Fleming, Ronan M. T., Antony, Paul M. A., Schwamborn, Jens C.
Published in Advanced science (09.01.2019)
Published in Advanced science (09.01.2019)
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Journal Article
Identification of novel inhibitors of dietary lipid absorption using zebrafish
Clifton, Justin D, Lucumi, Edinson, Myers, Michael C, Napper, Andrew, Hama, Kotaro, Farber, Steven A, Smith, 3rd, Amos B, Huryn, Donna M, Diamond, Scott L, Pack, Michael
Published in PloS one (25.08.2010)
Published in PloS one (25.08.2010)
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Journal Article
A pesticide and iPSC dopaminergic neuron screen identifies and classifies Parkinson-relevant pesticides
Paul, Kimberly C., Krolewski, Richard C., Lucumi Moreno, Edinson, Blank, Jack, Holton, Kristina M., Ahfeldt, Tim, Furlong, Melissa, Yu, Yu, Cockburn, Myles, Thompson, Laura K., Kreymerman, Alexander, Ricci-Blair, Elisabeth M., Li, Yu Jun, Patel, Heer B., Lee, Richard T., Bronstein, Jeff, Rubin, Lee L., Khurana, Vikram, Ritz, Beate
Published in Nature communications (16.05.2023)
Published in Nature communications (16.05.2023)
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Journal Article
Discovery of Potent Small-Molecule Inhibitors of Multidrug-Resistant Plasmodium falciparum Using a Novel Miniaturized High-Throughput Luciferase-Based Assay
Lucumi, Edinson, Darling, Claire, Jo, Hyunil, Napper, Andrew D, Chandramohanadas, Rajesh, Fisher, Nicholas, Shone, Alison E, Jing, Huiyan, Ward, Stephen A, Biagini, Giancarlo A, DeGrado, William F, Diamond, Scott L, Greenbaum, Doron C
Published in Antimicrobial Agents and Chemotherapy (01.09.2010)
Published in Antimicrobial Agents and Chemotherapy (01.09.2010)
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Journal Article
Publisher Correction: A pesticide and iPSC dopaminergic neuron screen identifies and classifies Parkinson-relevant pesticides
Paul, Kimberly C., Krolewski, Richard C., Lucumi Moreno, Edinson, Blank, Jack, Holton, Kristina M., Ahfeldt, Tim, Furlong, Melissa, Yu, Yu, Cockburn, Myles, Thompson, Laura K., Kreymerman, Alexander, Ricci-Blair, Elisabeth M., Li, Yu Jun, Patel, Heer B., Lee, Richard T., Bronstein, Jeff, Rubin, Lee L., Khurana, Vikram, Ritz, Beate
Published in Nature communications (23.06.2023)
Published in Nature communications (23.06.2023)
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Journal Article
Differentiation of neuroepithelial stem cells into functional dopaminergic neurons in 3D microfluidic cell culture
Moreno, Edinson Lucumi, Hachi, Siham, Hemmer, Kathrin, Trietsch, Sebastiaan J, Baumuratov, Aidos S, Hankemeier, Thomas, Vulto, Paul, Schwamborn, Jens C, Fleming, Ronan M T
Published in Lab on a chip (07.06.2015)
Published in Lab on a chip (07.06.2015)
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Journal Article
Novel high-throughput screen against Candida albicans identifies antifungal potentiators and agents effective against biofilms
LAFLEUR, Michael D, LUCUMI, Edinson, NAPPER, Andrew D, DIAMOND, Scott L, LEWIS, Kim
Published in Journal of antimicrobial chemotherapy (01.04.2011)
Published in Journal of antimicrobial chemotherapy (01.04.2011)
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Journal Article
Differentiation of neuroepithelial stem cells into functional dopaminergic neurons in 3D microfluidic cell cultureElectronic supplementary information (ESI) available: Supplementary movies 1-3. See DOI: 10.1039/c5lc00180c
Moreno, Edinson Lucumi, Hachi, Siham, Hemmer, Kathrin, Trietsch, Sebastiaan J, Baumuratov, Aidos S, Hankemeier, Thomas, Vulto, Paul, Schwamborn, Jens C, Fleming, Ronan M. T
Year of Publication 07.06.2015
Year of Publication 07.06.2015
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Journal Article
Discovery of novel inhibitors targeting enoyl–acyl carrier protein reductase in Plasmodium falciparum by structure-based virtual screening
Nicola, George, Smith, Colin A., Lucumi, Edinson, Kuo, Mack R., Karagyozov, Luchezar, Fidock, David A., Sacchettini, James C., Abagyan, Ruben
Published in Biochemical and biophysical research communications (06.07.2007)
Published in Biochemical and biophysical research communications (06.07.2007)
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Journal Article
Synthesis, biological activity, and X-ray crystal structural analysis of diaryl ether inhibitors of malarial enoyl acyl carrier protein reductase. Part 1: 4′-Substituted triclosan derivatives
Freundlich, Joel S., Anderson, John W., Sarantakis, Dimitri, Shieh, Hong-Ming, Yu, Min, Valderramos, Juan-Carlos, Lucumi, Edinson, Kuo, Mack, Jacobs, William R., Fidock, David A., Schiehser, Guy A., Jacobus, David P., Sacchettini, James C.
Published in Bioorganic & medicinal chemistry letters (01.12.2005)
Published in Bioorganic & medicinal chemistry letters (01.12.2005)
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Journal Article
Synthesis and biological activity of diaryl ether inhibitors of malarial enoyl acyl carrier protein reductase. Part 2: 2′-Substituted triclosan derivatives
Freundlich, Joel S., Yu, Min, Lucumi, Edinson, Kuo, Mack, Tsai, Han-Chun, Valderramos, Juan-Carlos, Karagyozov, Luchezar, Jacobs, William R., Schiehser, Guy A., Fidock, David A., Jacobus, David P., Sacchettini, James C.
Published in Bioorganic & medicinal chemistry letters (15.04.2006)
Published in Bioorganic & medicinal chemistry letters (15.04.2006)
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Journal Article
Erratum to “Synthesis, biological activity, and X-ray crystal structural analysis of diaryl ether inhibitors of malarial enoyl acyl carrier protein reductase. Part 1: 4′-Substituted triclosan derivatives” [Bioorg. Med. Chem. Lett. 15 (2005) 5247–5252]
Freundlich, Joel S., Anderson, John W., Sarantakis, Dimitri, Shieh, Hong-Ming, Yu, Min, Valderramos, Juan-Carlos, Lucumi, Edinson, Kuo, Mack, Jacobs, William R., Fidock, David A., Schiehser, Guy A., Jacobus, David P., Sacchettini, James C.
Published in Bioorganic & medicinal chemistry letters (01.07.2006)
Published in Bioorganic & medicinal chemistry letters (01.07.2006)
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Journal Article
Neuronal hyperactivity in a LRRK2-G2019S cellular model of Parkinson's Disease
Moreno, Edinson Lucumi, Hachi, Siham, Nickels, Sarah L, Kane, Kalid Iw, Moein, Masha, Schwamborn, Jens Christian, Skupin, Alexander, Pieter Vanden Berghe, Ronan Mt Fleming
Published in bioRxiv (23.06.2021)
Published in bioRxiv (23.06.2021)
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Paper
Coupling comprehensive pesticide-wide association study to iPSC dopaminergic screening identifies and classifies Parkinson-relevant pesticides
Paul, Kimberly C, Krolewski, Richard Carl, Moreno, Edinson Lucumi, Blank, Jack, Holton, Kristina M, Ahfeldt, Tim D, Furlong, Melissa, Yu, Yu, Cockburn, Myles, Thompson, Laura K, Bronstein, Jeff, Rubin, Lee L, Khurana, Vikram, Ritz, Beate
Published in bioRxiv (09.02.2022)
Published in bioRxiv (09.02.2022)
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