Search Results - "LUCKING ULRICH" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

The Novel ATR Inhibitor BAY 1895344 Is Efficacious as Monotherapy and Combined with DNA Damage-Inducing or Repair-Compromising Therapies in Preclinical Cancer Models

The Novel ATR Inhibitor BAY 1895344 Is Efficacious as Monotherapy and Combined with DNA Damage-Inducing or Repair-Compromising Therapies in Preclinical Cancer Models

by Wengner, Antje M, Siemeister, Gerhard, Lücking, Ulrich, Lefranc, Julien, Wortmann, Lars, Lienau, Philip, Bader, Benjamin, Bömer, Ulf, Moosmayer, Dieter, Eberspächer, Uwe, Golfier, Sven, Schatz, Christoph A, Baumgart, Simon J, Haendler, Bernard, Lejeune, Pascale, Schlicker, Andreas, von Nussbaum, Franz, Brands, Michael, Ziegelbauer, Karl, Mumberg, Dominik
Published in Molecular cancer therapeutics (01.01.2020)

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Identification of Atuveciclib (BAY 1143572), the First Highly Selective, Clinical PTEFb/CDK9 Inhibitor for the Treatment of Cancer

Identification of Atuveciclib (BAY 1143572), the First Highly Selective, Clinical PTEFb/CDK9 Inhibitor for the Treatment of Cancer

by Lücking, Ulrich, Scholz, Arne, Lienau, Philip, Siemeister, Gerhard, Kosemund, Dirk, Bohlmann, Rolf, Briem, Hans, Terebesi, Ildiko, Meyer, Kirstin, Prelle, Katja, Denner, Karsten, Bömer, Ulf, Schäfer, Martina, Eis, Knut, Valencia, Ray, Ince, Stuart, von Nussbaum, Franz, Mumberg, Dominik, Ziegelbauer, Karl, Klebl, Bert, Choidas, Axel, Nussbaumer, Peter, Baumann, Matthias, Schultz‐Fademrecht, Carsten, Rühter, Gerd, Eickhoff, Jan, Brands, Michael
Published in ChemMedChem (08.11.2017)

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Sulfoximines: A Neglected Opportunity in Medicinal Chemistry

Sulfoximines: A Neglected Opportunity in Medicinal Chemistry

by Lucking, Ulrich
Published in Angewandte Chemie International Edition (02.09.2013)

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Novel Pieces for the Emerging Picture of Sulfoximines in Drug Discovery: Synthesis and Evaluation of Sulfoximine Analogues of Marketed Drugs and Advanced Clinical Candidates

Novel Pieces for the Emerging Picture of Sulfoximines in Drug Discovery: Synthesis and Evaluation of Sulfoximine Analogues of Marketed Drugs and Advanced Clinical Candidates

by Sirvent, Juan Alberto, Lücking, Ulrich
Published in ChemMedChem (06.04.2017)

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A New, Practical One‐Pot Synthesis of Unprotected Sulfonimidamides by Transfer of Electrophilic NH to Sulfinamides

A New, Practical One‐Pot Synthesis of Unprotected Sulfonimidamides by Transfer of Electrophilic NH to Sulfinamides

by Izzo, Flavia, Schäfer, Martina, Stockman, Robert, Lücking, Ulrich
Published in Chemistry : a European journal (26.10.2017)

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Changing for the Better: Discovery of the Highly Potent and Selective CDK9 Inhibitor VIP152 Suitable for Once Weekly Intravenous Dosing for the Treatment of Cancer

Changing for the Better: Discovery of the Highly Potent and Selective CDK9 Inhibitor VIP152 Suitable for Once Weekly Intravenous Dosing for the Treatment of Cancer

by Lücking, Ulrich, Kosemund, Dirk, Böhnke, Niels, Lienau, Philip, Siemeister, Gerhard, Denner, Karsten, Bohlmann, Rolf, Briem, Hans, Terebesi, Ildiko, Bömer, Ulf, Schäfer, Martina, Ince, Stuart, Mumberg, Dominik, Scholz, Arne, Izumi, Raquel, Hwang, Stuart, von Nussbaum, Franz
Published in Journal of medicinal chemistry (12.08.2021)

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Damage Incorporated: Discovery of the Potent, Highly Selective, Orally Available ATR Inhibitor BAY 1895344 with Favorable Pharmacokinetic Properties and Promising Efficacy in Monotherapy and in Combination Treatments in Preclinical Tumor Models

Damage Incorporated: Discovery of the Potent, Highly Selective, Orally Available ATR Inhibitor BAY 1895344 with Favorable Pharmacokinetic Properties and Promising Efficacy in Monotherapy and in Combination Treatments in Preclinical Tumor Models

by Lücking, Ulrich, Wortmann, Lars, Wengner, Antje M, Lefranc, Julien, Lienau, Philip, Briem, Hans, Siemeister, Gerhard, Bömer, Ulf, Denner, Karsten, Schäfer, Martina, Koppitz, Marcus, Eis, Knut, Bartels, Florian, Bader, Benjamin, Bone, Wilhelm, Moosmayer, Dieter, Holton, Simon J, Eberspächer, Uwe, Grudzinska-Goebel, Joanna, Schatz, Christoph, Deeg, Gesa, Mumberg, Dominik, von Nussbaum, Franz
Published in Journal of medicinal chemistry (09.07.2020)

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Cover Picture: Novel Pieces for the Emerging Picture of Sulfoximines in Drug Discovery: Synthesis and Evaluation of Sulfoximine Analogues of Marketed Drugs and Advanced Clinical Candidates (ChemMedChem 7/2017)

Cover Picture: Novel Pieces for the Emerging Picture of Sulfoximines in Drug Discovery: Synthesis and Evaluation of Sulfoximine Analogues of Marketed Drugs and Advanced Clinical Candidates (ChemMedChem 7/2017)

by Sirvent, Juan Alberto, Lücking, Ulrich
Published in ChemMedChem (06.04.2017)

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The Kinase Chemogenomic Set (KCGS): An Open Science Resource for Kinase Vulnerability Identification

The Kinase Chemogenomic Set (KCGS): An Open Science Resource for Kinase Vulnerability Identification

by Wells, Carrow I, Al-Ali, Hassan, Andrews, David M, Asquith, Christopher R M, Axtman, Alison D, Dikic, Ivan, Ebner, Daniel, Ettmayer, Peter, Fischer, Christian, Frederiksen, Mathias, Futrell, Robert E, Gray, Nathanael S, Hatch, Stephanie B, Knapp, Stefan, Lücking, Ulrich, Michaelides, Michael, Mills, Caitlin E, Müller, Susanne, Owen, Dafydd, Picado, Alfredo, Saikatendu, Kumar S, Schröder, Martin, Stolz, Alexandra, Tellechea, Mariana, Turunen, Brandon J, Vilar, Santiago, Wang, Jinhua, Zuercher, William J, Willson, Timothy M, Drewry, David H
Published in International journal of molecular sciences (08.01.2021)

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Conformational Adaption May Explain the Slow Dissociation Kinetics of Roniciclib (BAY 1000394), a Type I CDK Inhibitor with Kinetic Selectivity for CDK2 and CDK9

Conformational Adaption May Explain the Slow Dissociation Kinetics of Roniciclib (BAY 1000394), a Type I CDK Inhibitor with Kinetic Selectivity for CDK2 and CDK9

by Ayaz, Pelin, Andres, Dorothee, Kwiatkowski, Dennis A, Kolbe, Carl-Christian, Lienau, Philip, Siemeister, Gerhard, Lücking, Ulrich, Stegmann, Christian M
Published in ACS chemical biology (17.06.2016)

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BAY-8400: A Novel Potent and Selective DNA-PK Inhibitor which Shows Synergistic Efficacy in Combination with Targeted Alpha Therapies

BAY-8400: A Novel Potent and Selective DNA-PK Inhibitor which Shows Synergistic Efficacy in Combination with Targeted Alpha Therapies

by Berger, Markus, Wortmann, Lars, Buchgraber, Philipp, Lücking, Ulrich, Zitzmann-Kolbe, Sabine, Wengner, Antje M, Bader, Benjamin, Bömer, Ulf, Briem, Hans, Eis, Knut, Rehwinkel, Hartmut, Bartels, Florian, Moosmayer, Dieter, Eberspächer, Uwe, Lienau, Philip, Hammer, Stefanie, Schatz, Christoph A, Wang, Qiuwen, Wang, Qi, Mumberg, Dominik, Nising, Carl F, Siemeister, Gerhard
Published in Journal of medicinal chemistry (09.09.2021)

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Discovery of BAY-298 and BAY-899: Tetrahydro-1,6-naphthyridine-Based, Potent, and Selective Antagonists of the Luteinizing Hormone Receptor Which Reduce Sex Hormone Levels in Vivo

Discovery of BAY-298 and BAY-899: Tetrahydro-1,6-naphthyridine-Based, Potent, and Selective Antagonists of the Luteinizing Hormone Receptor Which Reduce Sex Hormone Levels in Vivo

by Wortmann, Lars, Lindenthal, Bernhard, Muhn, Peter, Walter, Alexander, Nubbemeyer, Reinhard, Heldmann, Dieter, Sobek, Lothar, Morandi, Federica, Schrey, Anna K, Moosmayer, Dieter, Günther, Judith, Kuhnke, Joachim, Koppitz, Marcus, Lücking, Ulrich, Röhn, Ulrike, Schäfer, Martina, Nowak-Reppel, Katrin, Kühne, Ronald, Weinmann, Hilmar, Langer, Gernot
Published in Journal of medicinal chemistry (27.11.2019)

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New Opportunities for the Utilization of the Sulfoximine Group in Medicinal Chemistry from the Drug Designer's Perspective

New Opportunities for the Utilization of the Sulfoximine Group in Medicinal Chemistry from the Drug Designer's Perspective

by Lücking, Ulrich
Published in Chemistry : a European journal (07.10.2022)

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Frontispiece: New Opportunities for the Utilization of the Sulfoximine Group in Medicinal Chemistry from the Drug Designer's Perspective

Frontispiece: New Opportunities for the Utilization of the Sulfoximine Group in Medicinal Chemistry from the Drug Designer's Perspective

by Lücking, Ulrich
Published in Chemistry : a European journal (07.10.2022)

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Off-Target Decoding of a Multitarget Kinase Inhibitor by Chemical Proteomics

Off-Target Decoding of a Multitarget Kinase Inhibitor by Chemical Proteomics

by Missner, Enrico, Bahr, Inke, Badock, Volker, Lücking, Ulrich, Siemeister, Gerhard, Donner, Peter
Published in Chembiochem : a European journal of chemical biology (04.05.2009)

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BAY 1024767 blocks androgen receptor mutants found in castration-resistant prostate cancer patients

BAY 1024767 blocks androgen receptor mutants found in castration-resistant prostate cancer patients

by Sugawara, Tatsuo, Lejeune, Pascale, Köhr, Silke, Neuhaus, Roland, Faus, Hortensia, Gelato, Kathy A, Busemann, Matthias, Cleve, Arwed, Lücking, Ulrich, von Nussbaum, Franz, Brands, Michael, Mumberg, Dominik, Jung, Klaus, Stephan, Carsten, Haendler, Bernard
Published in Oncotarget (02.02.2016)

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Sulfoximine: Eine vernachlässigte Chance in der medizinischen Chemie

Sulfoximine: Eine vernachlässigte Chance in der medizinischen Chemie

by Lucking, Ulrich
Published in Angewandte Chemie (02.09.2013)

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Exploration of Novel Chemical Space: Synthesis and in vitro Evaluation of N‐Functionalized Tertiary Sulfonimidamides

Exploration of Novel Chemical Space: Synthesis and in vitro Evaluation of N‐Functionalized Tertiary Sulfonimidamides

by Izzo, Flavia, Schäfer, Martina, Lienau, Philip, Ganzer, Ursula, Stockman, Robert, Lücking, Ulrich
Published in Chemistry : a European journal (02.07.2018)

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Tuning glycoside reactivity: New tool for efficient oligosaccharide synthesis

Tuning glycoside reactivity: New tool for efficient oligosaccharide synthesis

by Douglas, NL, Ley, SV, Lucking, U, Warriner, SL
Published in Journal of the Chemical Society, Perkin Transactions 1 (1998)

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Increasing Complexity: A Practical Synthetic Approach to Three‐Dimensional, Cyclic Sulfoximines and First Insights into Their in Vitro Properties

Increasing Complexity: A Practical Synthetic Approach to Three‐Dimensional, Cyclic Sulfoximines and First Insights into Their in Vitro Properties

by Boulard, Emilie, Zibulski, Vivien, Oertel, Luisa, Lienau, Philip, Schäfer, Martina, Ganzer, Ursula, Lücking, Ulrich
Published in Chemistry : a European journal (01.04.2020)

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