Huntington's disease is a four-repeat tauopathy with tau nuclear rods
Fernández-Nogales, Marta, Cabrera, Jorge R, Santos-Galindo, María, Hoozemans, Jeroen J M, Ferrer, Isidro, Rozemuller, Annemieke J M, Hernández, Félix, Avila, Jesús, Lucas, José J
Published in Nature medicine (01.08.2014)
Published in Nature medicine (01.08.2014)
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Journal Article
Altered P2X7-receptor level and function in mouse models of Huntington's disease and therapeutic efficacy of antagonist administration
Díaz-Hernández, Miguel, Díez-Zaera, María, Sánchez-Nogueiro, Jesús, Gómez-Villafuertes, Rosa, Canals, Josep M, Alberch, Jordi, Miras-Portugal, María Teresa, Lucas, José J
Published in The FASEB journal (01.06.2009)
Published in The FASEB journal (01.06.2009)
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Journal Article
Altered Levels and Isoforms of Tau and Nuclear Membrane Invaginations in Huntington's Disease
Fernández-Nogales, Marta, Lucas, José J
Published in Frontiers in cellular neuroscience (17.01.2020)
Published in Frontiers in cellular neuroscience (17.01.2020)
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Journal Article
Prion-mediated neurodegeneration is associated with early impairment of the ubiquitin–proteasome system
McKinnon, Chris, Goold, Rob, Andre, Ralph, Devoy, Anny, Ortega, Zaira, Moonga, Julie, Linehan, Jacqueline M., Brandner, Sebastian, Lucas, José J., Collinge, John, Tabrizi, Sarah J.
Published in Acta neuropathologica (01.03.2016)
Published in Acta neuropathologica (01.03.2016)
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Journal Article
MAP2 Splicing is Altered in Huntington's Disease
Cabrera, Jorge Rubén, Lucas, José J.
Published in Brain pathology (Zurich, Switzerland) (01.03.2017)
Published in Brain pathology (Zurich, Switzerland) (01.03.2017)
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Journal Article
Huntington's disease-specific mis-splicing unveils key effector genes and altered splicing factors
Elorza, Ainara, Márquez, Yamile, Cabrera, Jorge R, Sánchez-Trincado, José Luis, Santos-Galindo, María, Hernández, Ivó H, Picó, Sara, Díaz-Hernández, Juan I, García-Escudero, Ramón, Irimia, Manuel, Lucas, José J
Published in Brain (London, England : 1878) (17.08.2021)
Published in Brain (London, England : 1878) (17.08.2021)
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Journal Article
P2X7 Receptor Upregulation in Huntington’s Disease Brains
Ollà, Ivana, Santos-Galindo, María, Elorza, Ainara, Lucas, José J.
Published in Frontiers in molecular neuroscience (06.10.2020)
Published in Frontiers in molecular neuroscience (06.10.2020)
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Journal Article
High concordance between hippocampal transcriptome of the mouse intra‐amygdala kainic acid model and human temporal lobe epilepsy
Conte, Giorgia, Parras, Alberto, Alves, Mariana, Ollà, Ivana, De Diego‐Garcia, Laura, Beamer, Edward, Alalqam, Razi, Ocampo, Alejandro, Mendez, Raúl, Henshall, David C., Lucas, José J., Engel, Tobias
Published in Epilepsia (Copenhagen) (01.12.2020)
Published in Epilepsia (Copenhagen) (01.12.2020)
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Journal Article
Prion-Associated Neurodegeneration Causes Both Endoplasmic Reticulum Stress and Proteasome Impairment in a Murine Model of Spontaneous Disease
Otero, Alicia, Betancor, Marina, Eraña, Hasier, Fernández Borges, Natalia, Lucas, José J, Badiola, Juan José, Castilla, Joaquín, Bolea, Rosa
Published in International journal of molecular sciences (05.01.2021)
Published in International journal of molecular sciences (05.01.2021)
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Journal Article
Huntingtin-mediated axonal transport requires arginine methylation by PRMT6
Migazzi, Alice, Scaramuzzino, Chiara, Anderson, Eric N., Tripathy, Debasmita, Hernández, Ivó H., Grant, Rogan A., Roccuzzo, Michela, Tosatto, Laura, Virlogeux, Amandine, Zuccato, Chiara, Caricasole, Andrea, Ratovitski, Tamara, Ross, Christopher A., Pandey, Udai B., Lucas, José J., Saudou, Frédéric, Pennuto, Maria, Basso, Manuela
Published in Cell reports (Cambridge) (13.04.2021)
Published in Cell reports (Cambridge) (13.04.2021)
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Journal Article
CPEB alteration and aberrant transcriptome-polyadenylation lead to a treatable SLC19A3 deficiency in Huntington's disease
Picó, Sara, Parras, Alberto, Santos-Galindo, María, Pose-Utrilla, Julia, Castro, Margarita, Fraga, Enrique, Hernández, Ivó H, Elorza, Ainara, Anta, Héctor, Wang, Nan, Martí-Sánchez, Laura, Belloc, Eulàlia, Garcia-Esparcia, Paula, Garrido, Juan J, Ferrer, Isidro, Macías-García, Daniel, Mir, Pablo, Artuch, Rafael, Pérez, Belén, Hernández, Félix, Navarro, Pilar, López-Sendón, José Luis, Iglesias, Teresa, Yang, X William, Méndez, Raúl, Lucas, José J
Published in Science translational medicine (29.09.2021)
Published in Science translational medicine (29.09.2021)
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Glycogen synthase kinase-3 inhibition is integral to long-term potentiation
Hooper, Claudie, Markevich, Vladimir, Plattner, Florian, Killick, Richard, Schofield, Emma, Engel, Tobias, Hernandez, Felix, Anderton, Brian, Rosenblum, Kobi, Bliss, Tim, Cooke, Sam F., Avila, Jesús, Lucas, José J., Giese, Karl Peter, Stephenson, John, Lovestone, Simon
Published in The European journal of neuroscience (01.01.2007)
Published in The European journal of neuroscience (01.01.2007)
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Journal Article
Role of Tau Protein in Both Physiological and Pathological Conditions
AVILA, JESUS, LUCAS, JOSE J, PEREZ, MAR, HERNANDEZ, FELIX
Published in Physiological reviews (01.04.2004)
Published in Physiological reviews (01.04.2004)
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Journal Article
Pathogenic SREK1 decrease in Huntington's disease lowers TAF1 mimicking X-linked dystonia parkinsonism
Hernández, Ivó H, Cabrera, Jorge R, Santos-Galindo, María, Sánchez-Martín, Manuel, Domínguez, Verónica, García-Escudero, Ramón, Pérez-Álvarez, María J, Pintado, Belén, Lucas, José J
Published in Brain (London, England : 1878) (01.07.2020)
Published in Brain (London, England : 1878) (01.07.2020)
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Journal Article
A new non-aggregative splicing isoform of human Tau is decreased in Alzheimer’s disease
García-Escudero, Vega, Ruiz-Gabarre, Daniel, Gargini, Ricardo, Pérez, Mar, García, Esther, Cuadros, Raquel, Hernández, Ivó H., Cabrera, Jorge R., García-Escudero, Ramón, Lucas, José J., Hernández, Félix, Ávila, Jesús
Published in Acta neuropathologica (01.07.2021)
Published in Acta neuropathologica (01.07.2021)
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Journal Article
Chronic lithium administration to FTDP‐17 tau and GSK‐3β overexpressing mice prevents tau hyperphosphorylation and neurofibrillary tangle formation, but pre‐formed neurofibrillary tangles do not revert
Engel, Tobias, Goñi‐Oliver, Paloma, Lucas, José J., Avila, Jesús, Hernández, Félix
Published in Journal of neurochemistry (01.12.2006)
Published in Journal of neurochemistry (01.12.2006)
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Journal Article
Pathogenic Mis-splicing of CPEB4 in Schizophrenia
Ollà, Ivana, Pardiñas, Antonio F., Parras, Alberto, Hernández, Ivó H., Santos-Galindo, María, Picó, Sara, Callado, Luis F., Elorza, Ainara, Rodríguez-López, Claudia, Fernández-Miranda, Gonzalo, Belloc, Eulàlia, Walters, James T.R., O’Donovan, Michael C., Méndez, Raúl, Toma, Claudio, Meana, J. Javier, Owen, Michael J., Lucas, José J.
Published in Biological psychiatry (1969) (15.08.2023)
Published in Biological psychiatry (1969) (15.08.2023)
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Journal Article
Protein oxidation in Huntington disease affects energy production and vitamin B6 metabolism
Sorolla, Ma Alba, Rodríguez-Colman, Ma José, Tamarit, Jordi, Ortega, Zaira, Lucas, José J., Ferrer, Isidre, Ros, Joaquim, Cabiscol, Elisa
Published in Free radical biology & medicine (15.08.2010)
Published in Free radical biology & medicine (15.08.2010)
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