Discovery of GDC-0853: A Potent, Selective, and Noncovalent Bruton’s Tyrosine Kinase Inhibitor in Early Clinical Development
Crawford, James J, Johnson, Adam R, Misner, Dinah L, Belmont, Lisa D, Castanedo, Georgette, Choy, Regina, Coraggio, Melis, Dong, Liming, Eigenbrot, Charles, Erickson, Rebecca, Ghilardi, Nico, Hau, Jonathan, Katewa, Arna, Kohli, Pawan Bir, Lee, Wendy, Lubach, Joseph W, McKenzie, Brent S, Ortwine, Daniel F, Schutt, Leah, Tay, Suzanne, Wei, BinQing, Reif, Karin, Liu, Lichuan, Wong, Harvey, Young, Wendy B
Published in Journal of medicinal chemistry (22.03.2018)
Published in Journal of medicinal chemistry (22.03.2018)
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Journal Article
Impact of Method of Preparation of Amorphous Solid Dispersions on Mechanical Properties: Comparison of Coprecipitation and Spray Drying
Hou, Hao Helen, Rajesh, Aniruddha, Pandya, Keyur M., Lubach, Joseph W., Muliadi, Ariel, Yost, Edward, Jia, Wei, Nagapudi, Karthik
Published in Journal of pharmaceutical sciences (01.02.2019)
Published in Journal of pharmaceutical sciences (01.02.2019)
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Journal Article
Characterization of Pharmaceutical Cocrystals and Salts by Dynamic Nuclear Polarization-Enhanced Solid-State NMR Spectroscopy
Zhao, Li, Hanrahan, Michael P, Chakravarty, Paroma, DiPasquale, Antonio G, Sirois, Lauren E, Nagapudi, Karthik, Lubach, Joseph W, Rossini, Aaron J
Published in Crystal growth & design (04.04.2018)
Published in Crystal growth & design (04.04.2018)
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Journal Article
Fast Acquisition of Proton‐Detected HETCOR Solid‐State NMR Spectra of Quadrupolar Nuclei and Rapid Measurement of NH Bond Lengths by Frequency Selective HMQC and RESPDOR Pulse Sequences
Wijesekara, Anuradha V., Venkatesh, Amrit, Lampkin, Bryan J., VanVeller, Brett, Lubach, Joseph W., Nagapudi, Karthik, Hung, Ivan, Gor'kov, Peter L., Gan, Zhehong, Rossini, Aaron J.
Published in Chemistry : a European journal (23.06.2020)
Published in Chemistry : a European journal (23.06.2020)
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Journal Article
Development of an Amorphous Solid Dispersion Formulation for Mitigating Mechanical Instability of Crystalline Form and Improving Bioavailability for Early Phase Clinical Studies
Chiang, Cheng W., Lubach, Joseph W., Chen, Tao, Chin, Steven, Ly, Justin, Zhang, Wei, Hou, Hao Helen, Nagapudi, Karthik
Published in Molecular pharmaceutics (01.05.2023)
Published in Molecular pharmaceutics (01.05.2023)
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Journal Article
Rapid Characterization of Formulated Pharmaceuticals Using Fast MAS 1H Solid-State NMR Spectroscopy
Hirsh, David A, Wijesekara, Anuradha V, Carnahan, Scott L, Hung, Ivan, Lubach, Joseph W, Nagapudi, Karthik, Rossini, Aaron J
Published in Molecular pharmaceutics (01.07.2019)
Published in Molecular pharmaceutics (01.07.2019)
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Journal Article
Acid-base interactions in amorphous solid dispersions of lumefantrine prepared by spray-drying and hot-melt extrusion using X-ray photoelectron spectroscopy
Song, Yang, Zemlyanov, Dmitry, Chen, Xin, Su, Ziyang, Nie, Haichen, Lubach, Joseph W., Smith, Daniel, Byrn, Stephen, Pinal, Rodolfo
Published in International journal of pharmaceutics (05.12.2016)
Published in International journal of pharmaceutics (05.12.2016)
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Journal Article
Magic angle spinning dynamic nuclear polarization solid-state NMR spectroscopy of γ-irradiated molecular organic solids
Carnahan, Scott L., Chen, Yunhua, Wishart, James F., Lubach, Joseph W., Rossini, Aaron J.
Published in Solid state nuclear magnetic resonance (01.06.2022)
Published in Solid state nuclear magnetic resonance (01.06.2022)
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Journal Article
Generality of Enhancing the Dissolution Rates of Free Acid Amorphous Solid Dispersions by the Incorporation of Sodium Hydroxide
Zhang, Helen J., Chiang, Cheng W., Maschmeyer-Tombs, Tristan, Conklin, Breanna, Napolitano, Jose G., Lubach, Joseph W., Nagapudi, Karthik, Mao, Chen, Chen, Yinshan
Published in Molecular pharmaceutics (01.07.2024)
Published in Molecular pharmaceutics (01.07.2024)
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Journal Article
Optimization of Spray-Drying Parameters for Formulation Development at Preclinical Scale
Nespi, Marika, Kuhn, Robert, Yen, Chun-Wan, Lubach, Joseph W., Leung, Dennis
Published in AAPS PharmSciTech (20.12.2021)
Published in AAPS PharmSciTech (20.12.2021)
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Journal Article
Probing the Distribution of Water in a Multi-Component System by Solid-State NMR Spectroscopy
Mistry, Pinal, Chakravarty, Paroma, Lubach, Joseph W.
Published in Pharmaceutical research (01.10.2016)
Published in Pharmaceutical research (01.10.2016)
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Journal Article
Exploring Molecular Speciation and Crystallization Mechanism of Amorphous 2-Phenylamino Nicotinic Acid
Kalra, Arjun, Lubach, Joseph W., Munson, Eric J., Li, Tonglei
Published in Pharmaceutical research (01.03.2018)
Published in Pharmaceutical research (01.03.2018)
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Journal Article
Utilizing Solid-State Techniques and Accelerated Conditions to Understand Particle Size Instability in Inhaled Drug Substances
Dobson, Daniel P., Yanez, Evelyn, Lubach, Joseph W., Stumpf, Andreas, Pellet, Jackson, Tso, Jerry
Published in Journal of pharmaceutical sciences (01.08.2021)
Published in Journal of pharmaceutical sciences (01.08.2021)
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Journal Article