Kynurenine pathway metabolomics predicts and provides mechanistic insight into multiple sclerosis progression
Lim, Chai K., Bilgin, Ayse, Lovejoy, David B., Tan, Vanessa, Bustamante, Sonia, Taylor, Bruce V., Bessede, Alban, Brew, Bruce J., Guillemin, Gilles J.
Published in Scientific reports (03.02.2017)
Published in Scientific reports (03.02.2017)
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Brain Co‐Delivery of Temozolomide and Cisplatin for Combinatorial Glioblastoma Chemotherapy
Zou, Yan, Wang, Yibin, Xu, Sen, Liu, Yanjie, Yin, Jinlong, Lovejoy, David B., Zheng, Meng, Liang, Xing‐Jie, Park, Jong Bae, Efremov, Yuri M., Ulasov, Ilya, Shi, Bingyang
Published in Advanced materials (Weinheim) (01.08.2022)
Published in Advanced materials (Weinheim) (01.08.2022)
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Novel thiosemicarbazone iron chelators induce up-regulation and phosphorylation of the metastasis suppressor N-myc down-stream regulated gene 1: a new strategy for the treatment of pancreatic cancer
Kovacevic, Zaklina, Chikhani, Sherin, Lovejoy, David B, Richardson, Des R
Published in Molecular pharmacology (01.10.2011)
Published in Molecular pharmacology (01.10.2011)
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Journal Article
Major Developments in the Design of Inhibitors along the Kynurenine Pathway
Jacobs, Kelly R, Castellano-Gonzalez, Gloria, Guillemin, Gilles J, Lovejoy, David B
Published in Current medicinal chemistry (01.01.2017)
Published in Current medicinal chemistry (01.01.2017)
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Brain co‐delivery of first‐line chemotherapy drug and epigenetic bromodomain inhibitor for multidimensional enhanced synergistic glioblastoma therapy
Liu, Yanjie, Wang, Wendie, Zhang, Dongya, Sun, Yajing, Li, Fangzhou, Zheng, Meng, Lovejoy, David B., Zou, Yan, Shi, Bingyang
Published in Exploration (Beijing, China) (01.08.2022)
Published in Exploration (Beijing, China) (01.08.2022)
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Behavioral effects of neuropeptides in rodent models of depression and anxiety
Rotzinger, Susan, Lovejoy, David A., Tan, Laura A.
Published in Peptides (New York, N.Y. : 1980) (01.04.2010)
Published in Peptides (New York, N.Y. : 1980) (01.04.2010)
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Journal Article
Biomimetic Dp44mT-nanoparticles selectively induce apoptosis in Cu-loaded glioblastoma resulting in potent growth inhibition
Ismail, Muhammad, Yang, Wen, Li, Yanfei, Wang, Yibin, He, Wenya, Wang, Jiefei, Muhammad, Pir, Chaston, Timothy B., Rehman, Fawad Ur, Zheng, Meng, Lovejoy, David B., Shi, Bingyang
Published in Biomaterials (01.10.2022)
Published in Biomaterials (01.10.2022)
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Journal Article
Antitumor Activity of Metal-Chelating Compound Dp44mT Is Mediated by Formation of a Redox-Active Copper Complex That Accumulates in Lysosomes
LOVEJOY, David B, JANSSON, Patric J, BRUNK, Ulf T, WONG, Jacky, PONKA, Prem, RICHARDSON, Des R
Published in Cancer research (Chicago, Ill.) (01.09.2011)
Published in Cancer research (Chicago, Ill.) (01.09.2011)
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Correlation between plasma and CSF concentrations of kynurenine pathway metabolites in Alzheimer's disease and relationship to amyloid-β and tau
Jacobs, Kelly R., Lim, Chai K., Blennow, Kaj, Zetterberg, Henrik, Chatterjee, Pratishtha, Martins, Ralph N., Brew, Bruce J., Guillemin, Gilles J., Lovejoy, David B.
Published in Neurobiology of aging (01.08.2019)
Published in Neurobiology of aging (01.08.2019)
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Journal Article
Understanding the role of the kynurenine pathway in human breast cancer immunobiology
Heng, Benjamin, Lim, Chai K, Lovejoy, David B, Bessede, Alban, Gluch, Laurence, Guillemin, Gilles J
Published in Oncotarget (09.02.2016)
Published in Oncotarget (09.02.2016)
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Journal Article
Differential kynurenine pathway metabolism in highly metastatic aggressive breast cancer subtypes: beyond IDO1-induced immunosuppression
Heng, Benjamin, Bilgin, Ayse A, Lovejoy, David B, Tan, Vanessa X, Milioli, Heloisa H, Gluch, Laurence, Bustamante, Sonia, Sabaretnam, Tharani, Moscato, Pablo, Lim, Chai K, Guillemin, Gilles J
Published in Breast cancer research : BCR (27.10.2020)
Published in Breast cancer research : BCR (27.10.2020)
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DNA nanoclew templated spherical nucleic acids for siRNA delivery
Ruan, Weimin, Zheng, Meng, An, Yang, Liu, Yuanyuan, Lovejoy, David B, Hao, Mingcong, Zou, Yan, Lee, Albert, Yang, Shu, Lu, Yiqing, Morsch, Marco, Chung, Roger, Shi, Bingyang
Published in Chemical communications (Cambridge, England) (2018)
Published in Chemical communications (Cambridge, England) (2018)
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Teneurin C-terminal associated peptide (TCAP)-1 attenuates the development and expression of naloxone-precipitated morphine withdrawal in male Swiss Webster mice
Mueller, Lauren E., Wexler, Roseanne S., Lovejoy, David A., Stein, Robert B., Slee, Andrew M.
Published in Psychopharmacology (01.08.2024)
Published in Psychopharmacology (01.08.2024)
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Dysregulation of the Kynurenine Pathway, Cytokine Expression Pattern, and Proteomics Profile Link to Symptomology in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)
Kavyani, Bahar, Ahn, Seong Beom, Missailidis, Daniel, Annesley, Sarah J., Fisher, Paul R., Schloeffel, Richard, Guillemin, Gilles J., Lovejoy, David B., Heng, Benjamin
Published in Molecular neurobiology (01.07.2024)
Published in Molecular neurobiology (01.07.2024)
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Novel Second-Generation Di-2-Pyridylketone Thiosemicarbazones Show Synergism with Standard Chemotherapeutics and Demonstrate Potent Activity against Lung Cancer Xenografts after Oral and Intravenous Administration in Vivo
Lovejoy, David B, Sharp, Danae M, Seebacher, Nicole, Obeidy, Peyman, Prichard, Thomas, Stefani, Christian, Basha, Maram T, Sharpe, Philip C, Jansson, Patric J, Kalinowski, Danuta S, Bernhardt, Paul V, Richardson, Des R
Published in Journal of medicinal chemistry (23.08.2012)
Published in Journal of medicinal chemistry (23.08.2012)
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