Randomized Study of CPX-351 for Medically Less-Fit Adults with Newly Diagnosed Acute Myeloid Leukemia or Other High-Grade Myeloid Neoplasm
Walter, Roland B., Othus, Megan, Orlowski, Kaysey F., McDaniel, Emily N., Scott, Bart L., Becker, Pamela S., Percival, Mary-Elizabeth M., Hendrie, Paul C., Medeiros, Bruno C, Chiarella, Michael T., Louie, Arthur C., Estey, Elihu H.
Published in Blood (08.12.2017)
Published in Blood (08.12.2017)
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Journal Article
The Impact of Hematopoietic Cell Transplantation on Survival: An Exploratory Analysis of a Phase 3 Study of CPX-351 Versus 7+3 in Older Patients with Newly Diagnosed, High-Risk/Secondary AML
Lin, Tara L, Cortes, Jorge E., Newell, Laura F., Ritchie, Ellen K., Stuart, Robert K., Strickland, Stephen A., Hogge, Donna, Solomon, Scott R, Stone, Richard M., Bixby, Dale L., Kolitz, Jonathan E., Schiller, Gary J., Wieduwilt, Matthew J., Ryan, Daniel H., Ryan, Robert, Chiarella, Michael, Louie, Arthur C., Uy, Geoffrey L.
Published in Blood (29.11.2018)
Published in Blood (29.11.2018)
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Journal Article
Efficacy and Safety of CPX-351 Versus 7+3 in a Subgroup of Older Patients with Newly Diagnosed Acute Myeloid Leukemia with Myelodysplasia-Related Changes (AML-MRC) Enrolled in a Phase 3 Study
Ryan, Daniel H., Uy, Geoffrey L., Cortes, Jorge E., Newell, Laura F., Ritchie, Ellen K., Stuart, Robert K., Strickland, Stephen A., Hogge, Donna, Solomon, Scott R, Stone, Richard M., Bixby, Dale L., Kolitz, Jonathan E., Schiller, Gary J., Wieduwilt, Matthew J., Ryan, Robert, Chiarella, Michael, Louie, Arthur C., Lancet, Jeffrey E.
Published in Blood (29.11.2018)
Published in Blood (29.11.2018)
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Journal Article
CPX-351 ((Cytarabine:Daunorubicin) Liposome Injection, (Vyxeos)) Does Not Prolong Qtcf Intervals, Requires No Dose Adjustment for Impaired Renal Function and Induces High Rates of Complete Remission in Acute Myeloid Leukemia
Lin, Tara L., Newell, Laura F., Stuart, Robert K., Michaelis, Laura C., Rubenstein, Stephen E., Pentikis, Helen S., Callahan, Timothy, Alvarez, Donna, Mayer, Lawrence D., Louie, Arthur C.
Published in Blood (03.12.2015)
Published in Blood (03.12.2015)
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Journal Article
Efficacy and Safety of CPX-351 Versus 7+3 in Older Adults with Secondary Acute Myeloid Leukemia: Combined Subgroup Analysis of Phase 2 and Phase 3 Studies
Lancet, Jeffrey E., Ritchie, Ellen K, Uy, Geoffrey L., Medeiros, Bruno C, Newell, Laura F., Lin, Tara L., Hogge, Donna, Stuart, Robert K., Strickland, Stephen A, Solomon, Scott R, Stone, Richard M., Kolitz, Jonathan E., Bixby, Dale L., Schiller, Gary J., Wieduwilt, Matthew J., Kovacsovics, Tibor, Ryan, Robert J., Chiarella, Michael, Louie, Arthur C, Cortes, Jorge E.
Published in Blood (08.12.2017)
Published in Blood (08.12.2017)
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Journal Article
Multivariate Efficacy Analysis of a Randomized, Phase 3 Study of CPX-351 Versus 7+3 in Older Adults with Treatment-Related Acute Myeloid Leukemia (AML) or AML with Myelodysplasia-Related Changes
Uy, Geoffrey L., Lancet, Jeffrey E., Cortes, Jorge E., Newell, Laura F., Lin, Tara L., Ritchie, Ellen K, Stuart, Robert K., Strickland, Stephen A, Hogge, Donna, Solomon, Scott R, Stone, Richard M., Bixby, Dale L., Kolitz, Jonathan E., Schiller, Gary J., Wieduwilt, Matthew J., Shemanski, Lynn, Chiarella, Michael, Louie, Arthur C, Medeiros, Bruno C
Published in Blood (08.12.2017)
Published in Blood (08.12.2017)
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Journal Article
Subanalysis of Patients with Secondary Acute Myeloid Leukemia (sAML) with Refractory Anemia with Excess of Blasts in Transformation (RAEB-t) Enrolled in a Phase 3 Study of CPX-351 Versus Conventional 7+3 Cytarabine and Daunorubicin
Lin, Tara L., Uy, Geoffrey L., Wieduwilt, Matthew J., Newell, Laura F., Stuart, Robert K., Medeiros, Bruno C, Schiller, Gary J., Rubenstein, Eric, Stock, Wendy, Warlick, Erica D., Foster, Matthew, Bixby, Dale L., Podoltsev, Nikolai A., An, Qi, Faderl, Stefan, Louie, Arthur C., Lancet, Jeffrey E.
Published in Blood (08.12.2017)
Published in Blood (08.12.2017)
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Journal Article
Rates of Adverse Events per Patient-Year in a Randomized, Phase 3 Study of CPX-351 Versus 7+3 in Older Adults with Newly Diagnosed, Treatment-Related Acute Myeloid Leukemia (AML) or AML with Myelodysplasia-Related Changes
Medeiros, Bruno C, Lancet, Jeffrey E., Cortes, Jorge E., Newell, Laura F., Lin, Tara L., Ritchie, Ellen K, Stuart, Robert K., Strickland, Stephen A., Hogge, Donna, Solomon, Scott R, Stone, Richard M., Bixby, Dale L., Kolitz, Jonathan E., Schiller, Gary J., Wieduwilt, Matthew J., Ryan, Robert J., Chiarella, Michael, Louie, Arthur C, Uy, Geoffrey L.
Published in Blood (08.12.2017)
Published in Blood (08.12.2017)
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Journal Article
Outcomes in Older Patients with Newly Diagnosed, High-risk/Secondary Acute Myeloid Leukemia (sAML) Who Received Consolidation in a Phase 3 Study of CPX-351 versus Conventional 7+3/5+2 Cytarabine and Daunorubicin
Kolitz, Jonathan, Strickland, Stephen A., Cortes, Jorge E., Hogge, Donna, Lancet, Jeffrey E., Goldberg, Stuart, Ryan, Robert J., Chiarella, Michael, Louie, Arthur C., Uy, Geoffrey L.
Published in Clinical lymphoma, myeloma and leukemia (01.09.2018)
Published in Clinical lymphoma, myeloma and leukemia (01.09.2018)
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Journal Article
Randomized Study of Liposomal Cytarabine and Daunorubicin (CPX-351) for Adults with Untreated High-Risk Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML) at High Risk of Treatment-Related Mortality
Walter, Roland B., Orlowski, Kaysey F., Powell, Morgan A., Becker, Pamela S., Hendrie, Paul C., Ostronoff, Fabiana, Ranker, Elizabeth M., Othus, Megan, Louie, Arthur C., Estey, Elihu H.
Published in Blood (06.12.2014)
Published in Blood (06.12.2014)
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Journal Article
Analysis of Efficacy By Age for Patients Aged 60-75 with Untreated Secondary Acute Myeloid Leukemia (AML) Treated with CPX-351 Liposome Injection Versus Conventional Cytarabine and Daunorubicin in a Phase III Trial
Medeiros, Bruno C., Lancet, Jeffrey E., Cortes, Jorge E., Newell, Laura F, Lin, Tara L., Ritchie, Ellen K., Stuart, Robert K., Strickland, Stephen A., Hogge, Donna, Solomon, Scott R., Stone, Richard M., Bixby, Dale L., Kolitz, Jonathan E., Schiller, Gary J., Wieduwilt, Matthew J., Ryan, Daniel H., Hoering, Antje, Chiarella, Michael T., Louie, Arthur C., Uy, Geoffrey L.
Published in Blood (02.12.2016)
Published in Blood (02.12.2016)
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Journal Article
Survival Following Allogeneic Hematopoietic Cell Transplantation in Older High-Risk Acute Myeloid Leukemia Patients Initially Treated with CPX-351 Liposome Injection Versus Standard Cytarabine and Daunorubicin: Subgroup Analysis of a Large Phase III Trial
Lancet, Jeffrey E., Hoering, Antje, Uy, Geoffrey L., Cortes, Jorge E., Newell, Laura F, Lin, Tara L., Ritchie, Ellen K., Stuart, Robert K., Strickland, Stephen A., Hogge, Donna, Solomon, Scott R., Stone, Richard M., Bixby, Dale L., Kolitz, Jonathan E., Schiller, Gary J., Wieduwilt, Matthew J., Ryan, Daniel H., Chiarella, Michael T., Louie, Arthur C., Medeiros, Bruno C.
Published in Blood (02.12.2016)
Published in Blood (02.12.2016)
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Journal Article
A Phase 3 Study of CPX-351 versus Conventional 7+3 Cytarabine and Daunorubicin: Subanalysis of Patients with Secondary Acute Myeloid Leukemia (sAML) with Refractory Anemia with Excess of Blasts in Transformation (RAEB-t)
Lin, Tara L., Wieduwilt, Matthew J., Newell, Laura F., Schiller, Gary J., Rubenstein, S. Eric, Stock, Wendy, Warlick, Erica, Bixby, Dale L., Podoltsev, Nikolai, An, Qi, Faderl, Stefan, Louie, Arthur C., Uy, Geoffrey L.
Published in Clinical lymphoma, myeloma and leukemia (01.09.2018)
Published in Clinical lymphoma, myeloma and leukemia (01.09.2018)
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Journal Article
CPX-351 Is Effective in Newly Diagnosed Older Patients with AML and with Multiple Risk Factors
Lancet, Jeffrey E, Cortes, Jorge E, Kovacsovics, Tibor, Hogge, Donna E., Kolitz, Jonathan E., Tallman, Martin S, Hoering, Antje, Chiarella, Michael T., Louie, Arthur C., Feldman, Eric
Published in Blood (16.11.2012)
Published in Blood (16.11.2012)
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Journal Article
Significance of Prior HSCT on the Outcome of Salvage Therapy with CPX-351 or Conventional Chemotherapy Among First Relapse AML Patients
Cortes, Jorge E., Feldman, Eric J, Goldberg, Stuart L., Rizzieri, David A., Louie, Arthur C., Kolitz, Jonathan E.
Published in Blood (18.11.2011)
Published in Blood (18.11.2011)
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Journal Article
CPX-351: A Randomized Phase 2b Study of CPX-351 v. Intensive Salvage Therapy in '65 Yo First Relapse AML Patients: Initial Efficacy and Safety Report
Cortes, Jorge E., Feldman, Eric J, Goldberg, Stuart L., Rizzieri, David A., Paulsen, Kim H., Louie, Arthur C., Kolitz, Jonathan E.
Published in Blood (18.11.2011)
Published in Blood (18.11.2011)
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Journal Article
Abstract 1292: Pharmacokinetics of CPX-351: A nano-scale liposomal fixed molar ratio of cytarabine-daunorubicin (Cyt:Daun) in patients with advanced leukemia
Feldman, Eric J., Lancet, Jeffrey E., Kolitz, Jonathan E., Trang, John M., Mayer, Lawrence D., Swenson, Chris E., Chiarella, Michael T., Louie, Arthur C.
Published in Cancer research (Chicago, Ill.) (15.04.2011)
Published in Cancer research (Chicago, Ill.) (15.04.2011)
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Journal Article
Phase 2B Randomized Study of CPX-351 Vs. Cytarabine (CYT) + Daunorubicin (DNR) (7+3 Regimen) In Newly Diagnosed AML Patients Aged 60–75
Lancet, Jeffrey E., Cortes, Jorge E., Hogge, Donna E., Tallman, Martin, Kovacsovics, Tibor, Damon, Lloyd E., Ritchie, Ellen, Komrokji, Rami S., Louie, Arthur C., Feldman, Eric J
Published in Blood (19.11.2010)
Published in Blood (19.11.2010)
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Journal Article
Phase IIb Randomized Study of CPX-351 Vs. Conventional Cytarabine + Daunorubicin in Newly Diagnosed AML Patients Aged 60-75: Safety Report
Lancet, Jeffrey E, Feldman, Eric J., Kolitz, Jonathan E., Tallman, Martin S., Hogge, Donna E., Komrokji, Rami S., Chiarella, Michael T., Louie, Arthur C.
Published in Blood (20.11.2009)
Published in Blood (20.11.2009)
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