A Randomized, Double-blind, Multicenter Trial Comparing Efficacy and Safety of Imipenem/Cilastatin/Relebactam Versus Piperacillin/Tazobactam in Adults With Hospital-acquired or Ventilator-associated Bacterial Pneumonia (RESTORE-IMI 2 Study)
Titov, Ivan, Wunderink, Richard G, Roquilly, Antoine, Rodríguez Gonzalez, Daniel, David-Wang, Aileen, Boucher, Helen W, Kaye, Keith S, Losada, Maria C, Du, Jiejun, Tipping, Robert, Rizk, Matthew L, Patel, Munjal, Brown, Michelle L, Young, Katherine, Kartsonis, Nicholas A, Butterton, Joan R, Paschke, Amanda, Chen, Luke F
Published in Clinical infectious diseases (06.12.2021)
Published in Clinical infectious diseases (06.12.2021)
Get full text
Journal Article
Evaluation of the dose range of etoricoxib in an acute pain setting using the postoperative dental pain model
Daniels, Stephen E, Bandy, Donald P, Christensen, Steven E, Boice, Judith, Losada, Maria C, Liu, Hui, Mehta, Anish, Peloso, Paul M
Published in The Clinical journal of pain (01.01.2011)
Published in The Clinical journal of pain (01.01.2011)
Get more information
Journal Article
Phase 2, Dose-Ranging Study of Relebactam with Imipenem-Cilastatin in Subjects with Complicated Intra-abdominal Infection
Lucasti, Christopher, Vasile, Liviu, Sandesc, Dorel, Venskutonis, Donatas, McLeroth, Patrick, Lala, Mallika, Rizk, Matthew L, Brown, Michelle L, Losada, Maria C, Pedley, Alison, Kartsonis, Nicholas A, Paschke, Amanda
Published in Antimicrobial agents and chemotherapy (01.10.2016)
Published in Antimicrobial agents and chemotherapy (01.10.2016)
Get full text
Journal Article
Participant- and Disease-Related Factors as Independent Predictors of Treatment Outcomes in the RESTORE-IMI 2 Clinical Trial: A Multivariable Regression Analysis
Martin-Loeches, Ignacio, Shorr, Andrew F, Kollef, Marin H, Du, Jiejun, Losada, Maria C, Paschke, Amanda, DeRyke, C Andrew, Wong, Michael, Jensen, Erin H, Chen, Luke F
Published in Open forum infectious diseases (01.06.2023)
Published in Open forum infectious diseases (01.06.2023)
Get full text
Journal Article
Imipenem/cilastatin/relebactam efficacy, safety and probability of target attainment in adults with hospital-acquired or ventilator-associated bacterial pneumonia among patients with baseline renal impairment, normal renal function, and augmented renal clearance
Roberts, Jason A, Nicolau, David P, Martin-Loeches, Ignacio, Deryke, C Andrew, Losada, Maria C, Du, Jiejun, Patel, Munjal, Rizk, Matthew L, Paschke, Amanda, Chen, Luke F
Published in JAC-antimicrobial resistance (01.04.2023)
Published in JAC-antimicrobial resistance (01.04.2023)
Get full text
Journal Article
Evaluation of multiday analgesia with etoricoxib in a double-blind, randomized controlled trial using the postoperative third-molar extraction dental pain model
Brown, Jean D, Daniels, Stephen E, Bandy, Donald P, Ko, Amy T, Gammaitoni, Arnold, Mehta, Anish, Boice, Judith A, Losada, Maria C, Peloso, Paul M
Published in The Clinical journal of pain (01.06.2013)
Published in The Clinical journal of pain (01.06.2013)
Get more information
Journal Article
A recombinant 63-kDa form of Bacillus anthracis protective antigen produced in the yeast Saccharomyces cerevisiae provides protection in rabbit and primate inhalational challenge models of anthrax infection
Hepler, Robert W., Kelly, Rosemarie, McNeely, Tessie B., Fan, Hongxia, Losada, Maria C., George, Hugh A., Woods, Andrea, Cope, Leslie D., Bansal, Alka, Cook, James C., Zang, Gina, Cohen, Steven L., Wei, Xiaorong, Keller, Paul M., Leffel, Elizabeth, Joyce, Joseph G., Pitt, Louise, Schultz, Loren D., Jansen, Kathrin U., Kurtz, Myra
Published in Vaccine (06.03.2006)
Published in Vaccine (06.03.2006)
Get full text
Journal Article
1080. Relebactam Increases Imipenem Activity Against Imipenem-Nonsusceptible and -Susceptible Pseudomonas aeruginosa and Enterobacterales: Assessment of Isolates from RESTORE-IMI 2
Hilbert, David W, Andrew DeRyke, C, Losada, Maria C, Moise, Pamela, Chen, Luke F, Young, Katherine
Published in Open forum infectious diseases (04.12.2021)
Published in Open forum infectious diseases (04.12.2021)
Get full text
Journal Article
2519. A Multi-national Phase 3, Randomized, Double-Blind, Active Comparator-Controlled Clinical Trial to Study the Safety, Tolerability, and Efficacy of Imipenem/Cilastatin/Relebactam (MK-7655A) Versus Piperacillin/Tazobactam in Subjects with Hospital-Acquired Bacterial Pneumonia or Ventilator-Associated Bacterial Pneumonia
Li, Junjie, Wei, Feng, Xiang, Peng, Tang, Zhengang, Ding, Lianshu, Losada, Maria C, Iamboliyska, Zlatka, Zhu, Mingfen, Guo, Xiaodan, Du, Xiaoling, Chen, Chang, Chen, Luke Francis, Zhou, Min, Qu, Jieming
Published in Open forum infectious diseases (27.11.2023)
Published in Open forum infectious diseases (27.11.2023)
Get full text
Journal Article
1574. Multivariate Regression Analysis to Determine Independent Predictors of Treatment Outcomes in the RESTORE-IMI 2 Trial
Tipping, Robert, Du, Jiejun, Losada, Maria C, Brown, Michelle L, Young, Katherine, Butterton, Joan R, Paschke, Amanda, Chen, Luke F
Published in Open forum infectious diseases (31.12.2020)
Published in Open forum infectious diseases (31.12.2020)
Get full text
Journal Article
1230. Clinical and Microbiologic Outcomes by Causative Pathogen in Hospital-Acquired or Ventilator-Associated Bacterial Pneumonia (HABP/VABP) Treated with Imipenem/Cilastatin (IMI)/Relebactam (REL) Versus Piperacillin/Tazobactam (PIP/TAZ)
Losada, Maria C, Maniar, Alok, Du, Jiejun, Brown, Michelle L, Young, Katherine, Hilbert, David W, Tipping, Robert, DeRyke, C Andrew, Butterton, Joan R, Paschke, Amanda, Chen, Luke F
Published in Open forum infectious diseases (31.12.2020)
Published in Open forum infectious diseases (31.12.2020)
Get full text
Journal Article
1460. Imipenem/Cilastatin (IMI)/Relebactam (REL) in Hospital-Acquired/Ventilator-Associated Bacterial Pneumonia (HABP/VABP): Subgroup Analyses of Critically Ill Patients in the RESTORE-IMI 2 Trial
Chen, Luke F, Losada, Maria C, Mahoney, Kathryn A, Du, Jiejun, Brown, Michelle L, Tipping, Robert, Young, Katherine, DeRyke, C Andrew, Butterton, Joan R, Paschke, Amanda
Published in Open forum infectious diseases (31.12.2020)
Published in Open forum infectious diseases (31.12.2020)
Get full text
Journal Article
A recombinant 63-kDa form ofBacillus anthracisprotective antigen produced in the yeastSaccharomyces cerevisiaeprovides protection in rabbit and primate inhalational challenge models of anthrax infection
Hepler, Robert W, Kelly, Rosemarie, McNeely, Tessie B, Fan, Hongxia, Losada, Maria C, George, Hugh A, Woods, Andrea, Cope, Leslie D, Bansal, Alka, Cook, James C, Zang, Gina, Cohen, Steven L, Wei, Xiaorong, Keller, Paul M, Leffel, Elizabeth, Joyce, Joseph G, Pitt, Louise, Schultz, Loren D, Jansen, Kathrin U, Kurtz, Myra
Published in Vaccine (06.03.2006)
Published in Vaccine (06.03.2006)
Get full text
Journal Article
rRNA operon restriction derived taxa for Streptomyces (RiDiTS)
Fulton, Thomas R., Losada, Maria C., Fluder, Eugene M., Chou, George T.
Published in FEMS microbiology letters (15.01.1995)
Published in FEMS microbiology letters (15.01.1995)
Get full text
Journal Article
Synthetic gene control region
SCHULTZ LOREN D, KURTZ MYRA, BROWNLOW MICHELLE K, LOSADA MARIA C, BRYAN JANINE, JANSEN KATHRIN UTE
Year of Publication 27.09.2011
Get full text
Year of Publication 27.09.2011
Patent
Synthetic gene control region
Bryan, Janine, Brownlow, Michelle K, Schultz, Loren D, Losada, Maria C, Jansen, Kathrin Ute, Kurtz, Myra
Year of Publication 27.09.2011
Get full text
Year of Publication 27.09.2011
Patent
rRNA operon restriction derived taxa for Streptomyces (RiDiTS)
Fulton, Thomas R., Losada, Maria C., Fluder, Eugene M., Chou, George T.
Published in FEMS microbiology letters (01.01.1995)
Published in FEMS microbiology letters (01.01.1995)
Get full text
Journal Article
SYNTHETIC GENE CONTROL REGION
BRYAN, JANINE, JANSEN, KATHRIN, LOSADA, MARIA, C, KURTZ, MYRA, BROWNLOW, MICHELLE, KAUPAS, SCHULTZ, LOREN
Year of Publication 22.09.2010
Get full text
Year of Publication 22.09.2010
Patent
Synthetic gene control region
SCHULTZ LOREN D, KURTZ MYRA, BROWNLOW MICHELLE K, LOSADA MARIA C, KURTZ STUART, BRYAN JANINE, JANSEN KATHRIN UTE
Year of Publication 18.02.2010
Get full text
Year of Publication 18.02.2010
Patent
SYNTHETIC GENE CONTROL REGION
BRYAN, JANINE, JANSEN, KATHRIN, LOSADA, MARIA, C, BROWNLOW, MICHELLE, KAUPAS, SCHULTZ, LOREN
Year of Publication 23.07.2008
Get full text
Year of Publication 23.07.2008
Patent