Generation and Cross-Coupling of Organozinc Reagents in Flow
Herath, Ananda, Molteni, Valentina, Pan, Shifeng, Loren, Jon
Published in Organic letters (07.12.2018)
Published in Organic letters (07.12.2018)
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One-Pot Electrochemical Nickel-Catalyzed Decarboxylative Sp2–Sp3 Cross-Coupling
Koyanagi, Takaoki, Herath, Ananda, Chong, Ashley, Ratnikov, Maxim, Valiere, Andrew, Chang, Jim, Molteni, Valentina, Loren, Jon
Published in Organic letters (01.02.2019)
Published in Organic letters (01.02.2019)
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Synthesis of a D3-symmetric "trefoil" knotted cyclophane
Arias, Karla I, Zysman-Colman, Eli, Loren, Jon C, Linden, Anthony, Siegel, Jay S
Published in Chemical communications (Cambridge, England) (14.09.2011)
Published in Chemical communications (Cambridge, England) (14.09.2011)
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Journal Article
Liver X receptor modulators: a review of recently patented compounds (2009 - 2012)
Loren, Jon, Huang, Zhihong, Laffitte, Bryan A, Molteni, Valentina
Published in Expert opinion on therapeutic patents (01.10.2013)
Published in Expert opinion on therapeutic patents (01.10.2013)
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Optimization of Platelet-Derived Growth Factor Receptor (PDGFR) Inhibitors for Duration of Action, as an Inhaled Therapy for Lung Remodeling in Pulmonary Arterial Hypertension
Shaw, Duncan E, Baig, Ferheen, Bruce, Ian, Chamoin, Sylvie, Collingwood, Stephen P, Cross, Sarah, Dayal, Satish, Drückes, Peter, Furet, Pascal, Furminger, Vikki, Haggart, Deborah, Hussey, Martin, Konstantinova, Irena, Loren, Jon C, Molteni, Valentina, Roberts, Sonia, Reilly, John, Saunders, Alex M, Stringer, Rowan, Sviridenko, Lilya, Thomas, Matthew, Thomson, Christopher G, Tomlins, Christine, Wen, Ben, Yeh, Vince, Pearce, Andrew C
Published in Journal of medicinal chemistry (08.09.2016)
Published in Journal of medicinal chemistry (08.09.2016)
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Journal Article
One-Pot Electrochemical Nickel-Catalyzed Decarboxylative Sp(2)-Sp(3) Cross-Coupling
Koyanagi, Takaoki, Herath, Ananda, Chong, Ashley, Ratnikov, Maxim, Valiere, Andrew, Chang, Jim, Molteni, Valentina, Loren, Jon
Published in Organic letters (01.02.2019)
Published in Organic letters (01.02.2019)
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Journal Article
One-Pot Electrochemical Nickel-Catalyzed Decarboxylative Sp 2 -Sp 3 Cross-Coupling
Koyanagi, Takaoki, Herath, Ananda, Chong, Ashley, Ratnikov, Maxim, Valiere, Andrew, Chang, Jim, Molteni, Valentina, Loren, Jon
Published in Organic letters (01.02.2019)
Published in Organic letters (01.02.2019)
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Journal Article
Selective DYRK1A Inhibitor for the Treatment of Type 1 Diabetes: Discovery of 6‑Azaindole Derivative GNF2133
Liu, Yahu A, Jin, Qihui, Zou, Yefen, Ding, Qiang, Yan, Shanshan, Wang, Zhicheng, Hao, Xueshi, Nguyen, Bao, Zhang, Xiaoyue, Pan, Jianfeng, Mo, Tingting, Jacobsen, Kate, Lam, Thanh, Wu, Tom Y.-H, Petrassi, H. Michael, Bursulaya, Badry, DiDonato, Michael, Gordon, W. Perry, Liu, Bo, Baaten, Janine, Hill, Robert, Nguyen-Tran, Vân, Qiu, Minhua, Zhang, You-Qing, Kamireddy, Anwesh, Espinola, Sheryll, Deaton, Lisa, Ha, Sukwon, Harb, George, Jia, Yong, Li, Jing, Shen, Weijun, Schumacher, Andrew M, Colman, Karyn, Glynne, Richard, Pan, Shifeng, McNamara, Peter, Laffitte, Bryan, Meeusen, Shelly, Molteni, Valentina, Loren, Jon
Published in Journal of medicinal chemistry (26.03.2020)
Published in Journal of medicinal chemistry (26.03.2020)
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Journal Article
Tuning a Protein‐Labeling Reaction to Achieve Highly Site Selective Lysine Conjugation
Pham, Grace H., Ou, Weijia, Bursulaya, Badry, DiDonato, Michael, Herath, Ananda, Jin, Yunho, Hao, Xueshi, Loren, Jon, Spraggon, Glen, Brock, Ansgar, Uno, Tetsuo, Geierstanger, Bernhard H., Cellitti, Susan E.
Published in Chembiochem : a European journal of chemical biology (16.04.2018)
Published in Chembiochem : a European journal of chemical biology (16.04.2018)
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Journal Article
Synthesis of a D-3-symmetric "trefoil" knotted cyclophane
Arias, Karla I., Zysman-Colman, Eli, Loren, Jon C., Linden, Anthony, Siegel, Jay S.
Published in Chemical communications (Cambridge, England) (01.01.2011)
Published in Chemical communications (Cambridge, England) (01.01.2011)
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Journal Article
TrkB inhibition by GNF-4256 slows growth and enhances chemotherapeutic efficacy in neuroblastoma xenografts
Croucher, Jamie L., Iyer, Radhika, Li, Nanxin, Molteni, Valentina, Loren, Jon, Gordon, W. Perry, Tuntland, Tove, Liu, Bo, Brodeur, Garrett M.
Published in Cancer chemotherapy and pharmacology (01.01.2015)
Published in Cancer chemotherapy and pharmacology (01.01.2015)
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Journal Article
A Dual Inhibitor of DYRK1A and GSK3β for β‐Cell Proliferation: Aminopyrazine Derivative GNF4877
Liu, Yahu A., Jin, Qihui, Ding, Qiang, Hao, Xueshi, Mo, Tingting, Yan, Shanshan, Zou, Yefen, Huang, Zhihong, Zhang, Xiaoyue, Gao, Wenqi, Wu, Tom Y.‐H., Li, Chun, Bursalaya, Badry, Di Donato, Michael, Zhang, You‐Qing, Deaton, Lisa, Shen, Weijun, Taylor, Brandon, Kamireddy, Anwesh, Harb, George, Li, Jing, Jia, Yong, Schumacher, Andrew M., Laffitte, Bryan, Glynne, Richard, Pan, Shifeng, McNamara, Peter, Molteni, Valentina, Loren, Jon
Published in ChemMedChem (19.08.2020)
Published in ChemMedChem (19.08.2020)
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Journal Article
(R)-2-Phenylpyrrolidine Substituted Imidazopyridazines: A New Class of Potent and Selective Pan-IRK Inhibitors
Choi, Ha-Soon, Rucker, Paul V., Wang, Zhicheng, Fan, Yi, Albaugh, Pamela, Chopiuk, Greg, Gessier, Francois, Sun, Fangxian, Adrian, Francisco, Liu, Guoxun, Hood, Tami, Li, Nanxin, Jia, Yong, Che, Jianwei, McCormack, Susan, Li, Allen, Li, Jie, Steffy, Auzon, Culazzo, AnneMarie, Tompkins, Celine, Van Phung, Kreusch, Andreas, Lu, Min, Hu, Bin, Chaudhary, Apurva, Prashad, Mahavir, Tuntland, Tove, Liu, Bo, Harris, Jennifer, Seidel, H. Martin, Loren, Jon, Molteni, Valentina
Published in ACS medicinal chemistry letters (01.05.2015)
Published in ACS medicinal chemistry letters (01.05.2015)
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Journal Article
Discovery of GNF-5837, a Selective TRK Inhibitor with Efficacy in Rodent Cancer Tumor Models
Albaugh, Pam, Fan, Yi, Mi, Yuan, Sun, Fangxian, Adrian, Francisco, Li, Nanxin, Jia, Yong, Sarkisova, Yelena, Kreusch, Andreas, Hood, Tami, Lu, Min, Liu, Guoxun, Huang, Shenlin, Liu, Zuosheng, Loren, Jon, Tuntland, Tove, Karanewsky, Donald S, Seidel, H. Martin, Molteni, Valentina
Published in ACS medicinal chemistry letters (09.02.2012)
Published in ACS medicinal chemistry letters (09.02.2012)
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Journal Article
(R)‑2-Phenylpyrrolidine Substituted Imidazopyridazines: A New Class of Potent and Selective Pan-TRK Inhibitors
Choi, Ha-Soon, Rucker, Paul V, Wang, Zhicheng, Fan, Yi, Albaugh, Pamela, Chopiuk, Greg, Gessier, Francois, Sun, Fangxian, Adrian, Francisco, Liu, Guoxun, Hood, Tami, Li, Nanxin, Jia, Yong, Che, Jianwei, McCormack, Susan, Li, Allen, Li, Jie, Steffy, Auzon, Culazzo, AnneMarie, Tompkins, Celine, Phung, Van, Kreusch, Andreas, Lu, Min, Hu, Bin, Chaudhary, Apurva, Prashad, Mahavir, Tuntland, Tove, Liu, Bo, Harris, Jennifer, Seidel, H. Martin, Loren, Jon, Molteni, Valentina
Published in ACS medicinal chemistry letters (14.05.2015)
Published in ACS medicinal chemistry letters (14.05.2015)
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