Maternal separation impairs long term-potentiation in CA1-CA3 synapses and hippocampal-dependent memory in old rats
Sousa, Vasco C, Vital, Joana, Costenla, Ana Rita, Batalha, Vânia L, Sebastião, Ana M, Ribeiro, Joaquim A, Lopes, Luísa V
Published in Neurobiology of aging (01.07.2014)
Published in Neurobiology of aging (01.07.2014)
Get full text
Journal Article
Adenosine and related drugs in brain diseases: present and future in clinical trials
Lopes, Luísa V, Sebastião, Ana M, Ribeiro, Joaquim A
Published in Current topics in medicinal chemistry (01.04.2011)
Published in Current topics in medicinal chemistry (01.04.2011)
Get more information
Journal Article
Adenosine A2A receptors and brain injury: broad spectrum of neuroprotection, multifaceted actions and "fine tuning" modulation
Chen, Jiang-Fan, Sonsalla, Patricia K, Pedata, Felicita, Melani, Alessia, Domenici, Maria Rosaria, Popoli, Patrizia, Geiger, Jonathan, Lopes, Luísa V, de Mendonça, Alexandre
Published in Progress in neurobiology (01.12.2007)
Published in Progress in neurobiology (01.12.2007)
Get full text
Journal Article
Enhancement of LTP in Aged Rats is Dependent on Endogenous BDNF
DIOGENES, Maria J, COSTENLA, Ana R, LOPES, Luisa V, JERONIMO-SANTOS, Andre, SOUSA, Vasco C, FONTINHA, Bruno M, RIBEIRO, Joaquim A, SEBASTIAO, Ana M
Published in Neuropsychopharmacology (01.08.2011)
Published in Neuropsychopharmacology (01.08.2011)
Get full text
Journal Article
Beneficial Effect of a Selective Adenosine A2A Receptor Antagonist in the APPswe/PS1dE9 Mouse Model of Alzheimer’s Disease
Faivre, Emilie, Coelho, Joana E., Zornbach, Katja, Malik, Enas, Baqi, Younis, Schneider, Marion, Cellai, Lucrezia, Carvalho, Kevin, Sebda, Shéhérazade, Figeac, Martin, Eddarkaoui, Sabiha, Caillierez, Raphaëlle, Chern, Yijuang, Heneka, Michael, Sergeant, Nicolas, Müller, Christa E., Halle, Annett, Buée, Luc, Lopes, Luisa V., Blum, David
Published in Frontiers in molecular neuroscience (12.07.2018)
Published in Frontiers in molecular neuroscience (12.07.2018)
Get full text
Journal Article
The Amyloid Precursor Protein C-Terminal Domain Alters CA1 Neuron Firing, Modifying Hippocampus Oscillations and Impairing Spatial Memory Encoding
Pousinha, Paula A., Mouska, Xavier, Bianchi, Daniela, Temido-Ferreira, Mariana, Rajão-Saraiva, Joana, Gomes, Rui, Fernandez, Sebastian P., Salgueiro-Pereira, Ana Rita, Gandin, Carine, Raymond, Elisabeth F., Barik, Jacques, Goutagny, Romain, Bethus, Ingrid, Lopes, Luisa V., Migliore, Michele, Marie, Hélène
Published in Cell reports (Cambridge) (08.10.2019)
Published in Cell reports (Cambridge) (08.10.2019)
Get full text
Journal Article
Mutant A53T α-synuclein improves rotarod performance before motor deficits and affects metabolic pathways
Guerreiro, Patrícia, Coelho, Joana, Sousa-Lima, Inês, Macedo, Paula, Lopes, Luisa, Outeiro, Tiago, Faria Pais, Teresa
Published in Neuromolecular medicine (01.03.2017)
Published in Neuromolecular medicine (01.03.2017)
Get full text
Journal Article
Neuroprotection afforded by adenosine A2A receptor blockade is modulated by corticotrophin-releasing factor (CRF) in glutamate injured cortical neurons
Valadas, Jorge S., Batalha, Vânia L., Ferreira, Diana G., Gomes, Rui, Coelho, Joana E., Sebastião, Ana M., Diógenes, Maria José, Lopes, Luísa V.
Published in Journal of neurochemistry (01.12.2012)
Published in Journal of neurochemistry (01.12.2012)
Get full text
Journal Article
Impact of in vivo chronic blockade of adenosine A2A receptors on the BDNF-mediated facilitation of LTP
Jerónimo-Santos, André, Batalha, Vânia L., Müller, Christa E., Baqi, Younis, Sebastião, Ana Maria, Lopes, Luisa V., Diógenes, Maria José
Published in Neuropharmacology (01.08.2014)
Published in Neuropharmacology (01.08.2014)
Get full text
Journal Article
Overexpression of Adenosine A2A receptors in rats: effects on depression, locomotion, and anxiety
Coelho, Joana, Nascimento Alves, Pedro, Canas, Paula M., Valadas, Jorge S., Shmidt, Tatiana, Batalha, Vânia, Ferreira, Diana G., Ribeiro, Joaquim, Bader, Michael, Cunha, Rodrigo A., Simões do Couto, Frederico, Lopes, Luisa
Published in Frontiers in psychiatry (2014)
Published in Frontiers in psychiatry (2014)
Get full text
Journal Article
Design, synthesis and evaluation of 2-aryl benzoxazoles as promising hit for the A2A receptor
Duroux, Romain, Renault, Nicolas, Cuelho, Joana Esteves, Agouridas, Laurence, Blum, David, Lopes, Luisa V., Melnyk, Patricia, Yous, Saïd
Published in Journal of enzyme inhibition and medicinal chemistry (01.12.2017)
Published in Journal of enzyme inhibition and medicinal chemistry (01.12.2017)
Get full text
Journal Article
α-synuclein interacts with PrPC to induce cognitive impairment through mGluR5 and NMDAR2B
Ferreira, Diana, Temido Ferreira, Mariana, Vicente Miranda, Hugo, Batalha, Vânia, Coelho, Joana, Szegö, Éva M, Marques-Morgado, Inês, Henriques Vaz, Sandra Cristina, Rhee, Jeong Seop, Schmitz, Matthias, Zerr, Inga, Lopes, Luisa, Outeiro, Tiago
Published in Nature neuroscience (01.11.2017)
Published in Nature neuroscience (01.11.2017)
Get full text
Journal Article
Stabilizing synapses
Blum, David, Lopes, Luísa V
Published in Science (American Association for the Advancement of Science) (05.11.2021)
Published in Science (American Association for the Advancement of Science) (05.11.2021)
Get full text
Journal Article
Exacerbation of C1q dysregulation, synaptic loss and memory deficits in tau pathology linked to neuronal adenosine A2A receptor
Carvalho, Kevin, Faivre, Emilie, Pietrowski, Marie J., Marques, Xavier, Gomez-Murcia, Victoria, Deleau, Aude, Huin, Vincent, Hansen, Jan N, Kozlov, Stanislav, Danis, Clément, Temido Ferreira, Mariana, Coelho, Joana, Mériaux, Céline, Eddarkaoui, Sabiha, Gras, Stéphanie Le, Dumoulin, Mélanie, Cellai, Lucrezia, Landrieu, Isabelle, Chern, Yijuang, Hamdane, Malika, Buée, Luc, Boutillier, Anne-Laurence, Levi, Sabine, Halle, Annett, Lopes, Luisa, Blum, David
Published in Brain (London, England : 1878) (01.11.2019)
Published in Brain (London, England : 1878) (01.11.2019)
Get full text
Journal Article
Glycation potentiates α-synuclein-associated neurodegeneration in synucleinopathies
Vicente Miranda, Hugo, Szego, Éva M, Oliveira, Luís M A, Breda, Carlo, Darendelioglu, Ekrem, de Oliveira, Rita M, Ferreira, Diana G, Gomes, Marcos A, Rott, Ruth, Oliveira, Márcia, Munari, Francesca, Enguita, Francisco J, Simões, Tânia, Rodrigues, Eva F, Heinrich, Michael, Martins, Ivo C, Zamolo, Irina, Riess, Olaf, Cordeiro, Carlos, Ponces-Freire, Ana, Lashuel, Hilal A, Santos, Nuno C, Lopes, Luisa V, Xiang, Wei, Jovin, Thomas M, Penque, Deborah, Engelender, Simone, Zweckstetter, Markus, Klucken, Jochen, Giorgini, Flaviano, Quintas, Alexandre, Outeiro, Tiago F
Published in Brain (London, England : 1878) (01.05.2017)
Published in Brain (London, England : 1878) (01.05.2017)
Get full text
Journal Article
Extracellular alpha-synuclein oligomers modulate synaptic transmission and impair ltp via NMDA-receptor activation
de Oliveira Diógenes Nogueira, Maria José, Dias, Raquel, Rombo, Diogo, Vicente Miranda, Hugo, Maiolino, Francesca, Guerreiro, Patrícia, Nasstrom, Thomas, Franquelim, Henri, Oliveira, Luís M.A., Castanho, Miguel, Lannfelt, Lars, Bergstrom, Joakim, Ingelsson, Martin, Quintas, Alexandre, Sebastião, Ana M, Lopes, Luisa, Outeiro, Tiago
Published in The Journal of neuroscience (22.08.2012)
Published in The Journal of neuroscience (22.08.2012)
Get full text
Journal Article
IL-17 triggers the onset of cognitive and synaptic deficits in early stages of Alzheimer’s disease
Brigas, Helena C., Ribeiro, Miguel, Coelho, Joana E., Gomes, Rui, Gomez-Murcia, Victoria, Carvalho, Kevin, Faivre, Emilie, Costa-Pereira, Sara, Darrigues, Julie, de Almeida, Afonso Antunes, Buée, Luc, Dunot, Jade, Marie, Hélène, Pousinha, Paula A., Blum, David, Silva-Santos, Bruno, Lopes, Luísa V., Ribot, Julie C.
Published in Cell reports (Cambridge) (31.08.2021)
Published in Cell reports (Cambridge) (31.08.2021)
Get full text
Journal Article
Prolactin-induced neuroprotection against glutamate excitotoxicity is mediated by the reduction of [Ca2+]i overload and NF-κB activation
Rivero-Segura, Nadia A, Flores-Soto, Edgar, García de la Cadena, Selene, Coronado-Mares, Isabel, Gomez-Verjan, Juan C, Ferreira, Diana G, Cabrera-Reyes, Erika Alejandra, Lopes, Luísa V, Massieu, Lourdes, Cerbón, Marco
Published in PloS one (05.05.2017)
Published in PloS one (05.05.2017)
Get full text
Journal Article