Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies
Zhou, Tongqing, Zhu, Jiang, Wu, Xueling, Moquin, Stephanie, Zhang, Baoshan, Acharya, Priyamvada, Georgiev, Ivelin S., Altae-Tran, Han R., Chuang, Gwo-Yu, Joyce, M. Gordon, Do Kwon, Young, Longo, Nancy S., Louder, Mark K., Luongo, Timothy, McKee, Krisha, Schramm, Chaim A., Skinner, Jeff, Yang, Yongping, Yang, Zhongjia, Zhang, Zhenhai, Zheng, Anqi, Bonsignori, Mattia, Haynes, Barton F., Scheid, Johannes F., Nussenzweig, Michel C., Simek, Melissa, Burton, Dennis R., Koff, Wayne C., Mullikin, James C., Connors, Mark, Shapiro, Lawrence, Nabel, Gary J., Mascola, John R., Kwong, Peter D.
Published in Immunity (Cambridge, Mass.) (22.08.2013)
Published in Immunity (Cambridge, Mass.) (22.08.2013)
Get full text
Journal Article
Broad and potent neutralization of HIV-1 by a gp41-specific human antibody
Huang, Jinghe, Ofek, Gilad, Laub, Leo, Louder, Mark K., Doria-Rose, Nicole A., Longo, Nancy S., Imamichi, Hiromi, Bailer, Robert T., Chakrabarti, Bimal, Sharma, Shailendra K., Alam, S. Munir, Wang, Tao, Yang, Yongping, Zhang, Baoshan, Migueles, Stephen A., Wyatt, Richard, Haynes, Barton F., Kwong, Peter D., Mascola, John R., Connors, Mark
Published in Nature (London) (15.11.2012)
Published in Nature (London) (15.11.2012)
Get full text
Journal Article
Rational Design of Envelope Identifies Broadly Neutralizing Human Monoclonal Antibodies to HIV-1
Wu, Xueling, Yang, Zhi-Yong, Li, Yuxing, Hogerkorp, Carl-Magnus, Schief, William R, Seaman, Michael S, Zhou, Tongqing, Schmidt, Stephen D, Wu, Lan, Xu, Ling, Longo, Nancy S, McKee, Krisha, O'Dell, Sijy, Louder, Mark K, Wycuff, Diane L, Feng, Yu, Nason, Martha, Doria-Rose, Nicole, Connors, Mark, Kwong, Peter D, Roederer, Mario, Wyatt, Richard T, Nabel, Gary J, Mascola, John R
Published in Science (American Association for the Advancement of Science) (13.08.2010)
Published in Science (American Association for the Advancement of Science) (13.08.2010)
Get full text
Journal Article
Germline-like predecessors of broadly neutralizing antibodies lack measurable binding to HIV-1 envelope glycoproteins: Implications for evasion of immune responses and design of vaccine immunogens
Xiao, Xiaodong, Chen, Weizao, Feng, Yang, Zhu, Zhongyu, Prabakaran, Ponraj, Wang, Yanping, Zhang, Mei-Yun, Longo, Nancy S., Dimitrov, Dimiter S.
Published in Biochemical and biophysical research communications (18.12.2009)
Published in Biochemical and biophysical research communications (18.12.2009)
Get full text
Journal Article
Developmental Pathway of the MPER-Directed HIV-1-Neutralizing Antibody 10E8
Soto, Cinque, Ofek, Gilad, Joyce, M Gordon, Zhang, Baoshan, McKee, Krisha, Longo, Nancy S, Yang, Yongping, Huang, Jinghe, Parks, Robert, Eudailey, Joshua, Lloyd, Krissey E, Alam, S Munir, Haynes, Barton F, Mullikin, James C, Connors, Mark, Mascola, John R, Shapiro, Lawrence, Kwong, Peter D
Published in PloS one (14.06.2016)
Published in PloS one (14.06.2016)
Get full text
Journal Article
HIV-1 Neutralizing Antibodies Display Dual Recognition of the Primary and Coreceptor Binding Sites and Preferential Binding to Fully Cleaved Envelope Glycoproteins
YUXING LI, O'DELL, Sijy, CHAKRABARTI, Bimal K, DORIA-ROSE, Nicole, ROEDERER, Mario, CONNORS, Mark, MASCOLA, John R, WYATT, Richard T, WILSON, Richard, XUELING WU, SCHMIDT, Stephen D, HOGERKORP, Carl-Magnus, LOUDER, Mark K, LONGO, Nancy S, POULSEN, Christian, GUENAGA, Javier
Published in Journal of Virology (01.10.2012)
Published in Journal of Virology (01.10.2012)
Get full text
Journal Article
Analysis of somatic hypermutation in X-linked hyper-IgM syndrome shows specific deficiencies in mutational targeting
Longo, Nancy S., Lugar, Patricia L., Yavuz, Sule, Zhang, Wen, Krijger, Peter H.L., Russ, Daniel E., Jima, Dereje D., Dave, Sandeep S., Grammer, Amrie C., Lipsky, Peter E.
Published in Blood (16.04.2009)
Published in Blood (16.04.2009)
Get full text
Journal Article
Characterization of the Human Ig Heavy Chain Antigen Binding Complementarity Determining Region 3 Using a Newly Developed Software Algorithm, JOINSOLVER
Souto-Carneiro, M. Margarida, Longo, Nancy S, Russ, Daniel E, Sun, Hong-wei, Lipsky, Peter E
Published in The Journal of immunology (1950) (01.06.2004)
Published in The Journal of immunology (1950) (01.06.2004)
Get full text
Journal Article
Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies
Doria-Rose, Nicole A., Schramm, Chaim A., Gorman, Jason, Moore, Penny L., Bhiman, Jinal N., DeKosky, Brandon J., Ernandes, Michael J., Georgiev, Ivelin S., Kim, Helen J., Pancera, Marie, Staupe, Ryan P., Altae-Tran, Han R., Bailer, Robert T., Crooks, Ema T., Cupo, Albert, Druz, Aliaksandr, Garrett, Nigel J., Hoi, Kam H., Kong, Rui, Louder, Mark K., Longo, Nancy S., McKee, Krisha, Nonyane, Molati, O’Dell, Sijy, Roark, Ryan S., Rudicell, Rebecca S., Schmidt, Stephen D., Sheward, Daniel J., Soto, Cinque, Wibmer, Constantinos Kurt, Yang, Yongping, Zhang, Zhenhai, Mullikin, James C., Binley, James M., Sanders, Rogier W., Wilson, Ian A., Moore, John P., Ward, Andrew B., Georgiou, George, Williamson, Carolyn, Abdool Karim, Salim S., Morris, Lynn, Kwong, Peter D., Shapiro, Lawrence, Mascola, John R.
Published in Nature (London) (01.05.2014)
Published in Nature (London) (01.05.2014)
Get full text
Journal Article
Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors
Zhou, Tongqing, Lynch, Rebecca M., Chen, Lei, Acharya, Priyamvada, Wu, Xueling, Doria-Rose, Nicole A., Joyce, M. Gordon, Lingwood, Daniel, Soto, Cinque, Bailer, Robert T., Ernandes, Michael J., Kong, Rui, Longo, Nancy S., Louder, Mark K., McKee, Krisha, O’Dell, Sijy, Schmidt, Stephen D., Tran, Lillian, Yang, Zhongjia, Druz, Aliaksandr, Luongo, Timothy S., Moquin, Stephanie, Srivatsan, Sanjay, Yang, Yongping, Zhang, Baoshan, Zheng, Anqi, Pancera, Marie, Kirys, Tatsiana, Georgiev, Ivelin S., Gindin, Tatyana, Peng, Hung-Pin, Yang, An-Suei, Mullikin, James C., Gray, Matthew D., Stamatatos, Leonidas, Burton, Dennis R., Koff, Wayne C., Cohen, Myron S., Haynes, Barton F., Casazza, Joseph P., Connors, Mark, Corti, Davide, Lanzavecchia, Antonio, Sattentau, Quentin J., Weiss, Robin A., West, Anthony P., Bjorkman, Pamela J., Scheid, Johannes F., Nussenzweig, Michel C., Shapiro, Lawrence, Mascola, John R., Kwong, Peter D.
Published in Cell (04.06.2015)
Published in Cell (04.06.2015)
Get full text
Journal Article
Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection
Wu, Xueling, Zhang, Zhenhai, Schramm, Chaim A, Joyce, M Gordon, Kwon, Young Do, Zhou, Tongqing, Sheng, Zizhang, Zhang, Baoshan, O'Dell, Sijy, McKee, Krisha, Georgiev, Ivelin S, Chuang, Gwo-Yu, Longo, Nancy S, Lynch, Rebecca M, Saunders, Kevin O, Soto, Cinque, Srivatsan, Sanjay, Yang, Yongping, Bailer, Robert T, Louder, Mark K, Mullikin, James C, Connors, Mark, Kwong, Peter D, Mascola, John R, Shapiro, Lawrence
Published in Cell (23.04.2015)
Published in Cell (23.04.2015)
Get full text
Journal Article
Focused Evolution of HIV-1 Neutralizing Antibodies Revealed by Structures and Deep Sequencing
Wu, Xueling, Zhou, Tongqing, Zhu, Jiang, Zhang, Baoshan, Georgiev, Ivelin, Wang, Charlene, Chen, Xuejun, Longo, Nancy S., Louder, Mark, McKee, Krisha, O'Dell, Sijy, Perfetto, Stephen, Schmidt, Stephen D., Shi, Wei, Wu, Lan, Yang, Yongping, Yang, Zhi-Yong, Yang, Zhongjia, Zhang, Zhenhai, Bonsignori, Mattia, Crump, John A., Kapiga, Saidi H., Sam, Noel E., Haynes, Barton F., Simek, Melissa, Burton, Dennis R., Koff, Wayne C., Doria-Rose, Nicole A., Connors, Mark, Mullikin, James C., Nabel, Gary J., Roederer, Mario, Shapiro, Lawrence, Kwong, Peter D., Mascola, John R.
Published in Science (American Association for the Advancement of Science) (16.09.2011)
Published in Science (American Association for the Advancement of Science) (16.09.2011)
Get full text
Journal Article
Isolation of human monoclonal antibodies from peripheral blood B cells
Huang, Jinghe, Doria-Rose, Nicole A, Longo, Nancy S, Laub, Leo, Lin, Chien-Li, Turk, Ellen, Kang, Byong H, Migueles, Stephen A, Bailer, Robert T, Mascola, John R, Connors, Mark
Published in Nature protocols (01.10.2013)
Published in Nature protocols (01.10.2013)
Get full text
Journal Article
Multiple Antibody Lineages in One Donor Target the Glycan-V3 Supersite of the HIV-1 Envelope Glycoprotein and Display a Preference for Quaternary Binding
Longo, Nancy S, Sutton, Matthew S, Shiakolas, Andrea R, Guenaga, Javier, Jarosinski, Marissa C, Georgiev, Ivelin S, McKee, Krisha, Bailer, Robert T, Louder, Mark K, O'Dell, Sijy, Connors, Mark, Wyatt, Richard T, Mascola, John R, Doria-Rose, Nicole A
Published in Journal of virology (01.12.2016)
Published in Journal of virology (01.12.2016)
Get full text
Journal Article