Exploring the Positional Attachment of Glycopeptide/β-lactam Heterodimers
Long, Daniel D., Aggen, James B., Chinn, Jason, Choi, Seok-Ki, Christensen, Burton G., Fatheree, Paul R., Green, David, Hegde, Sharath S., Judice, J. Kevin, Kaniga, Kone, Krause, Kevin M., Leadbetter, Michael, Linsell, Martin S., Marquess, Daniel G., Moran, Edmund J., Nodwell, Matthew B., Pace, John L., Trapp, Sean G., Turner, S. Derek
Published in Journal of antibiotics (01.10.2008)
Published in Journal of antibiotics (01.10.2008)
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Journal Article
A Multivalent Approach to Drug Discovery for Novel Antibiotics
Long, Daniel D., Aggen, James B., Christensen, Burton G., Judice, J. Kevin, Hegde, Sharath S., Kaniga, Kone, Krause, Kevin M., Linsell, Martin S., Moran, Edmund J., Pace, John L.
Published in Journal of antibiotics (01.10.2008)
Published in Journal of antibiotics (01.10.2008)
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Journal Article
Discovery of N-substituted-endo-3-(8-aza-bicyclo[3.2.1]oct-3-yl)-phenol and -phenyl carboxamide series of μ-opioid receptor antagonists
Jiang, Lan, Beattie, David T., Jacobsen, John R., Kintz, Samuel, Obedencio, Glenmar P., Saito, Daisuke, Stergiades, Ioanna, Vickery, Ross G., Long, Daniel D.
Published in Bioorganic & medicinal chemistry letters (01.07.2017)
Published in Bioorganic & medicinal chemistry letters (01.07.2017)
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Journal Article
Discovery of Axelopran (TD-1211): A Peripherally Restricted μ‑Opioid Receptor Antagonist
Long, Daniel D, Armstrong, Scott R, Beattie, David T, Campbell, Christina B, Church, Timothy J, Colson, Pierre-Jean, Dalziel, Sean M, Jacobsen, John R, Jiang, Lan, Obedencio, Glenmar P, Rapta, Miroslav, Saito, Daisuke, Stergiades, Ioanna, Tsuruda, Pamela R, Van Dyke, Priscilla M, Vickery, Ross G
Published in ACS medicinal chemistry letters (12.12.2019)
Published in ACS medicinal chemistry letters (12.12.2019)
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Journal Article
Discovery of TD-8954, a clinical stage 5-HT4 receptor agonist with gastrointestinal prokinetic properties
McKinnell, R. Murray, Armstrong, Scott R., Beattie, David T., Fatheree, Paul R., Long, Daniel D., Marquess, Daniel G., Shaw, Jeng-Pyng, Vickery, Ross G.
Published in Bioorganic & medicinal chemistry letters (15.07.2013)
Published in Bioorganic & medicinal chemistry letters (15.07.2013)
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Journal Article
A multivalent approach towards linked dual-pharmacology prostaglandin F receptor agonist/carbonic anhydrase-II inhibitors for the treatment of glaucoma
Long, Daniel D., Frieman, Bryan, Hegde, Sharath S., Hill, Craig M., Jiang, Lan, Kintz, Samuel, Marquess, Daniel G., Purkey, Hans, Shaw, Jeng-Pyng, Steinfeld, Tod, Wilson, Michael S., Wrench, Kevin
Published in Bioorganic & medicinal chemistry letters (15.02.2013)
Published in Bioorganic & medicinal chemistry letters (15.02.2013)
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Journal Article
The in vivo pharmacodynamics of the novel opioid receptor antagonist, TD-1211, in models of opioid-induced gastrointestinal and CNS activity
Armstrong, Scott R., Campbell, Christina B., Richardson, Carrie L., Vickery, Ross G., Tsuruda, Pamela R., Long, Daniel D., Hegde, Sharath S., Beattie, David T.
Published in Naunyn-Schmiedeberg's archives of pharmacology (01.06.2013)
Published in Naunyn-Schmiedeberg's archives of pharmacology (01.06.2013)
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Journal Article
Discovery, oral pharmacokinetics and in vivo efficacy of velusetrag, a highly selective 5-HT4 receptor agonist that has achieved proof-of-concept in patients with chronic idiopathic constipation
Long, Daniel D., Armstrong, Scott R., Beattie, David T., Choi, Seok-Ki, Fatheree, Paul R., Gendron, Roland A.L., Genov, Daniel, Goldblum, Adam A., Humphrey, Patrick P., Jiang, Lan, Marquess, Daniel G., Shaw, Jeng-Pyng, Smith, Jacqueline A.M., Turner, S. Derek, Vickery, Ross G.
Published in Bioorganic & medicinal chemistry letters (01.10.2012)
Published in Bioorganic & medicinal chemistry letters (01.10.2012)
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Journal Article
Discovery, oral pharmacokinetics and in vivo efficacy of a highly selective 5-HT4 receptor agonist: Clinical compound TD-2749
Long, Daniel D., Armstrong, Scott R., Beattie, David T., Choi, Seok-Ki, Fatheree, Paul R., Gendron, Roland A.L., Goldblum, Adam A., Humphrey, Patrick P., Marquess, Daniel G., Shaw, Jeng-Pyng, Smith, Jacqueline A.M., Derek Turner, S., Vickery, Ross G.
Published in Bioorganic & medicinal chemistry letters (15.07.2012)
Published in Bioorganic & medicinal chemistry letters (15.07.2012)
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Journal Article
A Multivalent Approach to the Design and Discovery of Orally Efficacious 5-HT4 Receptor Agonists
McKinnell, R. Murray, Armstrong, Scott R, Beattie, David T, Choi, Seok-Ki, Fatheree, Paul R, Gendron, Roland A. L, Goldblum, Adam, Humphrey, Patrick P, Long, Daniel D, Marquess, Daniel G, Shaw, J. P, Smith, Jacqueline A. M, Turner, S. Derek, Vickery, Ross G
Published in Journal of medicinal chemistry (10.09.2009)
Published in Journal of medicinal chemistry (10.09.2009)
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Journal Article
Helix-Forming Carbohydrate Amino Acids
Claridge, Timothy D. W., Long, Daniel D., Baker, Christopher M., Odell, Barbara, Grant, Guy H., Edwards, Alison A., Tranter, George E., Fleet, George W. J., Smith, Martin D.
Published in Journal of organic chemistry (18.03.2005)
Published in Journal of organic chemistry (18.03.2005)
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Journal Article
PRODRUGS OF JAK INHIBITOR COMPOUND FOR TREATMENT OF GASTROINTESTINAL INFLAMMATORY BOWEL DISEASE
DONNA A A WILTON, LONG DANIEL D, RYAN HUDSON, MANDY LOO, PATRICK J BRASSIL
Year of Publication 10.12.2020
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Year of Publication 10.12.2020
Patent
야누스 키나아제 저해제의 글루쿠로니드 프로드러그
LONG DANIEL D, HUDSON RYAN, BRASSIL PATRICK J, LOO MANDY, WILTON DONNA A.A
Year of Publication 30.01.2020
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Year of Publication 30.01.2020
Patent
NEPRILYSIN INHIBITORS
MELISSA FLEURY, DONNA A A WILTON, LONG DANIEL D, ADAM D HUGHES, ANNE-MARIE BEAUSOLEIL
Year of Publication 20.12.2018
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Year of Publication 20.12.2018
Patent
5-BIPHENYL-4-HETEROARYLCARBONYLAMINO-PENTANOIC ACID DERIVATIVES AS NEPRILYSIN INHIBITORS
MELISSA FLEURY, DONNA A A WILTON, LONG DANIEL D, ADAM D HUGHES, ANNE-MARIE BEAUSOLEIL
Year of Publication 20.12.2018
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Year of Publication 20.12.2018
Patent
위장관 염증 질환의 치료를 위한 JAK 저해제 화합물의 프로드러그
LONG DANIEL D, HUDSON RYAN, BRASSIL PATRICK J, LOO MANDY, WILTON DONNA A.A
Year of Publication 11.07.2018
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Year of Publication 11.07.2018
Patent