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Andersen, Henrik Sune, Olsen, Ole H, Iversen, Lars F, Sørensen, Anette L. P, Mortensen, Steen B, Christensen, Michael S, Branner, Sven, Hansen, Thomas K, Lau, Jesper F, Jeppesen, Lone, Moran, Edmond J, Su, Jing, Bakir, Farid, Judge, Luke, Shahbaz, Manou, Collins, Tassie, Vo, Todd, Newman, Michael J, Ripka, William C, Møller, Niels Peter H
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Published in Journal of medicinal chemistry (26.09.2002)
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Xanomeline, an M1/M4 preferring muscarinic cholinergic receptor agonist, produces antipsychotic-like activity in rats and mice
Shannon, Harlan E., Rasmussen, Kurt, Bymaster, Frank P., Hart, John C., Peters, Steven C., Swedberg, Michael D.B., Jeppesen, Lone, Sheardown, Malcolm J., Sauerberg, Per, Fink-Jensen, Anders
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Published in Schizophrenia research (01.05.2000)
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Synthesis and Pharmacological Evaluation of Dimeric Muscarinic Acetylcholine Receptor Agonists
Christopoulos, A, Grant, M K, Ayoubzadeh, N, Kim, O N, Sauerberg, P, Jeppesen, L, El-Fakahany, E E
Published in The Journal of pharmacology and experimental therapeutics (01.09.2001)
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Published in The Journal of pharmacology and experimental therapeutics (01.09.2001)
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Process Development and Scale-Up of the PPAR Agonist NNC 61-4655
Deussen, Heinz-Josef, Jeppesen, Lone, Schärer, Norbert, Junager, Finn, Bentzen, Bjørn, Weber, Beat, Weil, Volker, Mozer, Sandor Josef, Sauerberg, Per
Published in Organic process research & development (01.05.2004)
Published in Organic process research & development (01.05.2004)
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Structure–activity relationships of dimeric PPAR agonists
Sauerberg, Per, Mogensen, John P., Jeppesen, Lone, Svensson, L. Anders, Fleckner, Jan, Nehlin, Jan, Wulff, Erik M., Pettersson, Ingrid
Published in Bioorganic & medicinal chemistry letters (01.03.2005)
Published in Bioorganic & medicinal chemistry letters (01.03.2005)
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Muscarinic Receptor Agonists, Like Dopamine Receptor Antagonist Antipsychotics, Inhibit Conditioned Avoidance Response in Rats
Shannon, H E, Hart, J C, Bymaster, F P, Calligaro, D O, DeLapp, N W, Mitch, C H, Ward, J S, Fink-Jensen, A, Sauerberg, P, Jeppesen, L, Sheardown, M J, Swedberg, M D
Published in The Journal of pharmacology and experimental therapeutics (01.08.1999)
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Published in The Journal of pharmacology and experimental therapeutics (01.08.1999)
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Novel Tricyclic-α-alkyloxyphenylpropionic Acids: Dual PPARα/γ Agonists with Hypolipidemic and Antidiabetic Activity
Sauerberg, Per, Pettersson, Ingrid, Jeppesen, Lone, Bury, Paul S, Mogensen, John P, Wassermann, Karsten, Brand, Christian L, Sturis, Jeppe, Wöldike, Helle F, Fleckner, Jan, Andersen, Anne-Sofie T, Mortensen, Steen B, Svensson, L. Anders, Rasmussen, Hanne B, Lehmann, Søren V, Polivka, Zdenek, Sindelar, Karel, Panajotova, Vladimira, Ynddal, Lars, Wulff, Erik M
Published in Journal of medicinal chemistry (14.02.2002)
Published in Journal of medicinal chemistry (14.02.2002)
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Xanomeline, an M 1/M 4 preferring muscarinic cholinergic receptor agonist, produces antipsychotic-like activity in rats and mice
Shannon, Harlan E., Rasmussen, Kurt, Bymaster, Frank P., Hart, John C., Peters, Steven C., Swedberg, Michael D.B., Jeppesen, Lone, Sheardown, Malcolm J., Sauerberg, Per, Fink-Jensen, Anders
Published in Schizophrenia research (05.05.2000)
Published in Schizophrenia research (05.05.2000)
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Selective PPAR Agonists for the Treatment of Type 2 Diabetes
NEHLIN, JAN O., MOGENSEN, JOHN P., PETTERSON, INGRID, JEPPESEN, LONE, FLECKNER, JAN, WULFF, ERIK M., SAUERBERG, PER
Published in Annals of the New York Academy of Sciences (01.05.2006)
Published in Annals of the New York Academy of Sciences (01.05.2006)
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Identification and Synthesis of a Novel Selective Partial PPARδ Agonist with Full Efficacy on Lipid Metabolism In Vitro and In Vivo
Sauerberg, Per, Olsen, Grith S, Jeppesen, Lone, Mogensen, John P, Pettersson, Ingrid, Jeppesen, Claus B, Daugaard, Jens R, Galsgaard, Elisabeth D, Ynddal, Lars, Fleckner, Jan, Panajotova, Vladimira, Polivka, Zdenek, Pihera, Pavel, Havranek, Miroslav, Wulff, Erik M
Published in Journal of medicinal chemistry (05.04.2007)
Published in Journal of medicinal chemistry (05.04.2007)
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Design of potent PPARα agonists
Sauerberg, Per, Mogensen, John P., Jeppesen, Lone, Bury, Paul S., Fleckner, Jan, Olsen, Grith S., Jeppesen, Claus B., Wulff, Erik M., Pihera, Pavel, Havranek, Miroslav, Polivka, Zdenek, Pettersson, Ingrid
Published in Bioorganic & medicinal chemistry letters (01.06.2007)
Published in Bioorganic & medicinal chemistry letters (01.06.2007)
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Identification and synthesis of a novel selective partial PPARdelta agonist with full efficacy on lipid metabolism in vitro and in vivo
Sauerberg, Per, Olsen, Grith S, Jeppesen, Lone, Mogensen, John P, Pettersson, Ingrid, Jeppesen, Claus B, Daugaard, Jens R, Galsgaard, Elisabeth D, Ynddal, Lars, Fleckner, Jan, Panajotova, Vladimira, Polivka, Zdenek, Pihera, Pavel, Havranek, Miroslav, Wulff, Erik M
Published in Journal of medicinal chemistry (05.04.2007)
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Published in Journal of medicinal chemistry (05.04.2007)
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Large Dimeric Ligands with Favorable Pharmacokinetic Properties and Peroxisome Proliferator-Activated Receptor Agonist Activity in Vitro and in Vivo
Sauerberg, Per, Bury, Paul S, Mogensen, John P, Deussen, Heinz-Josef, Pettersson, Ingrid, Fleckner, Jan, Nehlin, Jan, Frederiksen, Klaus S, Albrektsen, Tatjana, Din, Nanni, Svensson, L. Anders, Ynddal, Lars, Wulff, Erik M, Jeppesen, Lone
Published in Journal of medicinal chemistry (06.11.2003)
Published in Journal of medicinal chemistry (06.11.2003)
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Design of potent PPARalpha agonists
Sauerberg, Per, Mogensen, John P, Jeppesen, Lone, Bury, Paul S, Fleckner, Jan, Olsen, Grith S, Jeppesen, Claus B, Wulff, Erik M, Pihera, Pavel, Havranek, Miroslav, Polivka, Zdenek, Pettersson, Ingrid
Published in Bioorganic & medicinal chemistry letters (01.06.2007)
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Published in Bioorganic & medicinal chemistry letters (01.06.2007)
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Design and synthesis of novel PPARα/γ/δ triple activators using a known PPARα/γ dual activator as structural template
Mogensen, John P, Jeppesen, Lone, Bury, Paul S, Pettersson, Ingrid, Fleckner, Jan, Nehlin, Jan, Frederiksen, Klaus S, Albrektsen, Tatjana, Din, Nanni, Mortensen, Steen B, Svensson, L.Anders, Wassermann, Karsten, Wulff, Erik M, Ynddal, Lars, Sauerberg, Per
Published in Bioorganic & medicinal chemistry letters (01.01.2003)
Published in Bioorganic & medicinal chemistry letters (01.01.2003)
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The muscarinic receptor agonist BuTAC, a novel potential antipsychotic, does not impair learning and memory in mouse passive avoidance
Rasmussen, Thøger, Fink-Jensen, Anders, Sauerberg, Per, Swedberg, Michael D.B., Thomsen, Christian, Sheardown, Malcolm J., Jeppesen, Lone, Calligaro, David O., DeLapp, Neil W., Whitesitt, Celia, Ward, John S., Shannon, Harlan E., Bymaster, Frank P.
Published in Schizophrenia research (15.04.2001)
Published in Schizophrenia research (15.04.2001)
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Potential role of muscarinic receptors in schizophrenia
Bymaster, Frank P., Shannon, Harlan E., Rasmussen, Kurt, DeLapp, Neil W., Ward, John S., Calligaro, David O., Mitch, Charles H., Whitesitt, Celia, Ludvigsen, Thomas S., Sheardown, Malcolm, Swedberg, Michael, Rasmussen, Thøger, Olesen, Preben H., Jeppesen, Lone, Sauerberg, Per, Fink-Jensen, Anders
Published in Life sciences (1973) (1999)
Published in Life sciences (1973) (1999)
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Xanomeline compared to other muscarinic agents on stimulation of phosphoinositide hydrolysis in vivo and other cholinomimetic effects
Bymaster, Frank P., Carter, Petra A., Peters, Steven C., Zhang, Wei, Ward, John S., Mitch, Charles H., Calligaro, David O., Whitesitt, Celia A., DeLapp, Neil, Shannon, Harlan E., Rimvall, Karin, Jeppesen, Lone, Sheardown, Malcolm J., Fink-Jensen, Anders, Sauerberg, Per
Published in Brain research (08.06.1998)
Published in Brain research (08.06.1998)
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Muscarinic receptor agonists decrease cocaine self-administration rates in drug-naive mice
Rasmussen, Thøger, Sauerberg, Per, Nielsen, Erik B, Swedberg, Michael D.B, Thomsen, Christian, Sheardown, Malcolm J, Jeppesen, Lone, Calligaro, David O, DeLapp, Neil W, Whitesitt, Celia, Ward, John S, Shannon, Harlan E, Bymaster, Frank P, Fink-Jensen, Anders
Published in European journal of pharmacology (25.08.2000)
Published in European journal of pharmacology (25.08.2000)
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