Nuclear receptor coactivators: master regulators of human health and disease
Dasgupta, Subhamoy, Lonard, David M, O'Malley, Bert W
Published in Annual review of medicine (01.01.2014)
Published in Annual review of medicine (01.01.2014)
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XBP1 links the 12-hour clock to NAFLD and regulation of membrane fluidity and lipid homeostasis
Meng, Huan, Gonzales, Naomi M, Lonard, David M, Putluri, Nagireddy, Zhu, Bokai, Dacso, Clifford C, York, Brian, O'Malley, Bert W
Published in Nature communications (04.12.2020)
Published in Nature communications (04.12.2020)
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Steroid receptor coactivator-3 inhibition generates breast cancer antitumor immune microenvironment
Han, Sang Jun, Sung, Nuri, Wang, Jin, O'Malley, Bert W, Lonard, David M
Published in Breast cancer research : BCR (31.10.2022)
Published in Breast cancer research : BCR (31.10.2022)
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Targeting NSD2-mediated SRC-3 liquid-liquid phase separation sensitizes bortezomib treatment in multiple myeloma
Liu, Jing, Xie, Ying, Guo, Jing, Li, Xin, Wang, Jingjing, Jiang, Hongmei, Peng, Ziyi, Wang, Jingya, Wang, Sheng, Li, Qian, Ye, Linquan, Zhong, Yuping, Zhang, Qiguo, Liu, Xiaozhi, Lonard, David M, Wang, Jin, O'Malley, Bert W, Liu, Zhiqiang
Published in Nature communications (15.02.2021)
Published in Nature communications (15.02.2021)
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Prostate cancer-associated mutations in speckle-type POZ protein (SPOP) regulate steroid receptor coactivator 3 protein turnover
Geng, Chuandong, He, Bin, Xu, Limei, Barbieri, Christopher E., Eedunuri, Vijay Kumar, Chew, Sue Anne, Zimmermann, Martin, Bond, Richard, Shou, John, Li, Chao, Blattner, Mirjam, Lonard, David M., Demichelis, Francesca, Coarfa, Cristian, Rubin, Mark A., Zhou, Pengbo, O'Malley, Bert W., Mitsiades, Nicholas
Published in Proceedings of the National Academy of Sciences - PNAS (23.04.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (23.04.2013)
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Development of potent small-molecule inhibitors to drug the undruggable steroid receptor coactivator-3
Song, Xianzhou, Chen, Jianwei, Zhao, Mingkun, Zhang, Chengwei, Yu, Yang, Lonard, David M., Chow, Dar-Chone, Palzkill, Timothy, Xu, Jianming, O’Malley, Bert W., Wang, Jin
Published in Proceedings of the National Academy of Sciences - PNAS (03.05.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (03.05.2016)
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Inhibition of SRC-3 as a potential therapeutic strategy for aggressive mantle cell lymphoma
Bijou, Imani, Liu, Yang, Lu, Dong, Chen, Jianwei, Sloan, Shelby, Alinari, Lapo, Lonard, David M, O'Malley, Bert W, Wang, Michael, Wang, Jin
Published in PloS one (29.04.2024)
Published in PloS one (29.04.2024)
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Steroid receptor coactivators in Treg and Th17 cell biology and function
Gilad, Yosi, Shimon, Ortal, Han, Sang Jun, Lonard, David M, O'Malley, Bert W
Published in Frontiers in immunology (18.04.2024)
Published in Frontiers in immunology (18.04.2024)
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Characterization of a Steroid Receptor Coactivator Small Molecule Stimulator that Overstimulates Cancer Cells and Leads to Cell Stress and Death
Wang, Lei, Yu, Yang, Chow, Dar-Chone, Yan, Fei, Hsu, Chih-Chao, Stossi, Fabio, Mancini, Michael A., Palzkill, Timothy, Liao, Lan, Zhou, Suoling, Xu, Jianming, Lonard, David M., O’Malley, Bert W.
Published in Cancer cell (10.08.2015)
Published in Cancer cell (10.08.2015)
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SRC-3 Coactivator Governs Dynamic Estrogen-Induced Chromatin Looping Interactions during Transcription
Panigrahi, Anil K., Foulds, Charles E., Lanz, Rainer B., Hamilton, Ross A., Yi, Ping, Lonard, David M., Tsai, Ming-Jer, Tsai, Sophia Y., O’Malley, Bert W.
Published in Molecular cell (17.05.2018)
Published in Molecular cell (17.05.2018)
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Defining the mammalian coactivation of hepatic 12-h clock and lipid metabolism
Meng, Huan, Gonzales, Naomi M., Jung, Sung Yun, Lu, Yue, Putluri, Nagireddy, Zhu, Bokai, Dacso, Clifford C., Lonard, David M., O’Malley, Bert W.
Published in Cell reports (Cambridge) (08.03.2022)
Published in Cell reports (Cambridge) (08.03.2022)
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Proteomic Analysis of Coregulators Bound to ERα on DNA and Nucleosomes Reveals Coregulator Dynamics
Foulds, Charles E., Feng, Qin, Ding, Chen, Bailey, Suzanna, Hunsaker, Tamra L., Malovannaya, Anna, Hamilton, Ross A., Gates, Leah A., Zhang, Zheng, Li, Chunshu, Chan, Doug, Bajaj, Amol, Callaway, Celetta G., Edwards, Dean P., Lonard, David M., Tsai, Sophia Y., Tsai, Ming-Jer, Qin, Jun, O’Malley, Bert W.
Published in Molecular cell (25.07.2013)
Published in Molecular cell (25.07.2013)
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ERK3 signals through SRC-3 coactivator to promote human lung cancer cell invasion
Long, Weiwen, Foulds, Charles E, Qin, Jun, Liu, Jian, Ding, Chen, Lonard, David M, Solis, Luisa M, Wistuba, Ignacio I, Tsai, Sophia Y, Tsai, Ming-Jer, O'Malley, Bert W
Published in The Journal of clinical investigation (01.05.2012)
Published in The Journal of clinical investigation (01.05.2012)
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Steroid receptor coactivator 3 (SRC-3/AIB1) is enriched and functional in mouse and human Tregs
Nikolai, Bryan C, Jain, Prashi, Cardenas, David L, York, Brian, Feng, Qin, McKenna, Neil J, Dasgupta, Subhamoy, Lonard, David M, O'Malley, Bert W
Published in Scientific reports (09.02.2021)
Published in Scientific reports (09.02.2021)
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Journal Article
SRC-3 inhibition blocks tumor growth of pancreatic ductal adenocarcinoma
Song, Xianzhou, Chen, Hui, Zhang, Chengwei, Yu, Yang, Chen, Zhongyuan, Liang, Han, Van Buren, George, McElhany, Amy L., Fisher, William E., Lonard, David M., O'Malley, Bert W., Wang, Jin
Published in Cancer letters (01.02.2019)
Published in Cancer letters (01.02.2019)
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