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Vaborbactam: Spectrum of Beta-Lactamase Inhibition and Impact of Resistance Mechanisms on Activity in Enterobacteriaceae
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A synthetic lipopeptide targeting top-priority multidrug-resistant Gram-negative pathogens
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Effect and Safety of Meropenem–Vaborbactam versus Best-Available Therapy in Patients with Carbapenem-Resistant Enterobacteriaceae Infections: The TANGO II Randomized Clinical Trial
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Published in Infectious diseases and therapy (01.12.2018)
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QPX7728, An Ultra-Broad-Spectrum B-Lactamase Inhibitor for Intravenous and Oral Therapy: Overview of Biochemical and Microbiological Characteristics
Lomovskaya, Olga, Tsivkovski, Ruslan, Sun, Dongxu, Reddy, Raja, Totrov, Maxim, Hecker, Scott, Griffith, David, Loutit, Jeffery, Dudley, Michael
Published in Frontiers in microbiology (05.07.2021)
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Waltzing transporters and 'the dance macabre' between humans and bacteria
Lomovskaya, Olga, Zgurskaya, Helen I, Totrov, Maxim, Watkins, William J
Published in Nature reviews. Drug discovery (01.01.2007)
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Molecular determinants of avoidance and inhibition of Pseudomonas aeruginosa MexB efflux pump
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Published in mBio (31.08.2023)
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Predictive Rules of Efflux Inhibition and Avoidance in Pseudomonas aeruginosa
Mehla, Jitender, Malloci, Giuliano, Mansbach, Rachael, López, Cesar A, Tsivkovski, Ruslan, Haynes, Keith, Leus, Inga V, Grindstaff, Sally B, Cascella, Robert H, D'Cunha, Napoleon, Herndon, Liam, Hengartner, Nicolas W, Margiotta, Enrico, Atzori, Alessio, Vargiu, Attilio V, Manrique, Pedro D, Walker, John K, Lomovskaya, Olga, Ruggerone, Paolo, Gnanakaran, S, Rybenkov, Valentin V, Zgurskaya, Helen I
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Published in mBio (19.01.2021)
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Multidrug Pump Inhibitors Uncover Remarkable Activity of Plant Antimicrobials
TEGOS, George, STERMITZ, Frank R, LOMOVSKAYA, Olga, LEWIS, Kim
Published in Antimicrobial Agents and Chemotherapy (01.10.2002)
Published in Antimicrobial Agents and Chemotherapy (01.10.2002)
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Identification and characterization of CIM-1, a carbapenemase that adds to the family of resistance factors against last resort antibiotics
Wang, Yu, Sapula, Sylvia A., Whittall, Jonathan J., Blaikie, Jack M., Lomovskaya, Olga, Venter, Henrietta
Published in Communications biology (07.03.2024)
Published in Communications biology (07.03.2024)
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Use of an Efflux Pump Inhibitor To Determine the Prevalence of Efflux Pump-Mediated Fluoroquinolone Resistance and Multidrug Resistance in Pseudomonas aeruginosa
KRIENGKAUYKIAT, Jane, PORTER, Edith, LOMOVSKAYA, Olga, WONG-BERINGER, Annie
Published in Antimicrobial Agents and Chemotherapy (01.02.2005)
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In Vitro Pharmacodynamics of Levofloxacin and Other Aerosolized Antibiotics under Multiple Conditions Relevant to Chronic Pulmonary Infection in Cystic Fibrosis
KING, Paula, LOMOVSKAYA, Olga, GRIFFITH, David C, BURNS, Jane L, DUDLEY, Michael N
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High-Level Pacidamycin Resistance in Pseudomonas aeruginosa Is Mediated by an Opp Oligopeptide Permease Encoded by the opp-fabI Operon
MISTRY, Anita, WARREN, Mark S, CUSICK, John K, KARKHOFF-SCHWEIZER, Roxann R, LOMOVSKAYA, Olga, SCHWEIZER, Herbert P
Published in Antimicrobial Agents and Chemotherapy (01.11.2013)
Published in Antimicrobial Agents and Chemotherapy (01.11.2013)
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Identification and Characterization of Inhibitors of Multidrug Resistance Efflux Pumps in Pseudomonas aeruginosa: Novel Agents for Combination Therapy
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Published in Antimicrobial Agents and Chemotherapy (01.01.2001)
Published in Antimicrobial Agents and Chemotherapy (01.01.2001)
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MexXY-OprM Efflux Pump Is Necessary for Adaptive Resistance of Pseudomonas aeruginosa to Aminoglycosides
HOCQUET, Didier, VOGNE, Christelle, EL GARCH, Farid, VEJUX, Anne, GOTOH, Naomasa, LEE, Angela, LOMOVSKAVA, Olga, PLESIAT, Patrick
Published in Antimicrobial Agents and Chemotherapy (01.04.2003)
Published in Antimicrobial Agents and Chemotherapy (01.04.2003)
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Interplay between Efflux Pumps May Provide Either Additive or Multiplicative Effects on Drug Resistance
Lee, A, Mao, W, Warren, M S, Mistry, A, Hoshino, K, Okumura, R, Ishida, H, Lomovskaya, O
Published in Journal of Bacteriology (01.06.2000)
Published in Journal of Bacteriology (01.06.2000)
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Drug-Induced Conformational Changes in Multidrug Efflux Transporter AcrB from Haemophilus influenzae
DASTIDAR, Vishakha, WEIMIN MAO, LOMOVSKAYA, Olga, ZGURSKAYA, Helen I
Published in Journal of Bacteriology (01.08.2007)
Published in Journal of Bacteriology (01.08.2007)
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