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Published in European journal of medicinal chemistry (15.11.2024)
Published in European journal of medicinal chemistry (15.11.2024)
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Binding versus Enzymatic Processing of ε‑Trimethyllysine Dioxygenase Substrate Analogues
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Published in ACS medicinal chemistry letters (10.11.2022)
Published in ACS medicinal chemistry letters (10.11.2022)
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Targeting Carnitine Biosynthesis: Discovery of New Inhibitors against γ‑Butyrobetaine Hydroxylase
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Published in Journal of medicinal chemistry (27.03.2014)
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Acute and long‐term administration of palmitoylcarnitine induces muscle‐specific insulin resistance in mice
Liepinsh, Edgars, Makrecka‐Kuka, Marina, Makarova, Elina, Volska, Kristine, Vilks, Karlis, Sevostjanovs, Eduards, Antone, Unigunde, Kuka, Janis, Vilskersts, Reinis, Lola, Daina, Loza, Einars, Grinberga, Solveiga, Dambrova, Maija
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Published in BioFactors (Oxford) (10.09.2017)
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Selective inhibition of OCTN2 is more effective than inhibition of gamma-butyrobetaine dioxygenase to decrease the availability of l-carnitine and to reduce myocardial infarct size
Liepinsh, Edgars, Makrecka, Marina, Kuka, Janis, Cirule, Helena, Makarova, Elina, Sevostjanovs, Eduards, Grinberga, Solveiga, Vilskersts, Reinis, Lola, Daina, Loza, Einars, Stonans, Ilmars, Pugovics, Osvalds, Dambrova, Maija
Published in Pharmacological research (01.07.2014)
Published in Pharmacological research (01.07.2014)
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N‑Leucinyl Benzenesulfonamides as Structurally Simplified Leucyl-tRNA Synthetase Inhibitors
Charlton, Michael H, Aleksis, Rihards, Saint-Leger, Adélaïde, Gupta, Arya, Loza, Einars, Ribas de Pouplana, Lluís, Kaula, Ilze, Gustina, Daina, Madre, Marina, Lola, Daina, Jaudzems, Kristaps, Edmund, Grace, Randall, Christopher P, Kime, Louise, O’Neill, Alex J, Goessens, Wil, Jirgensons, Aigars, Finn, Paul W
Published in ACS medicinal chemistry letters (08.02.2018)
Published in ACS medicinal chemistry letters (08.02.2018)
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Novel amide derivatives as inhibitors of histone deacetylase: Design, synthesis and SAR
Andrianov, Victor, Gailite, Vija, Lola, Daina, Loza, Einars, Semenikhina, Valentina, Kalvinsh, Ivars, Finn, Paul, Petersen, Kamille Dumong, Ritchie, James W.A., Khan, Nagma, Tumber, Anthony, Collins, Laura S., Vadlamudi, Sree M., Björkling, Fredrik, Sehested, Maxwell
Published in European journal of medicinal chemistry (01.03.2009)
Published in European journal of medicinal chemistry (01.03.2009)
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USE OF 3-CARBOXY-N-ETHYL-N,N-DIMETHYLPROPAN-1-AMINIUM SALTS IN THE TREATMENT OF CARDIOVASCULAR DISEASE
LOZA EINARS, KALVINS IVARS, LIEPINS EDGARS, PUGOVICS OSVALDS, KUKA JANIS, GRINBERGA SOLVEIGA, DAMBROVA MAIJA, LOLA DAINA, STONANS ILMARS, VILSKERSTS REINIS
Year of Publication 19.12.2013
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Year of Publication 19.12.2013
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Use of 3-carboxy-N-ethyl-N,N-dimethylpropan-1-aminium salts in the treatment of cardiovascular disease
Stonans, Ilmars, Lola, Daina, Kuka, Janis, Vilskersts, Reinis, Loza, Einars, Pugovics, Osvalds, Kalvins, Ivars, Liepins, Edgars, Dambrova, Maija, Grinberga, Solveiga
Year of Publication 16.07.2019
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Year of Publication 16.07.2019
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USE OF 3-CARBOXY-N-ETHYL-N,N-DIMETHYLPROPAN-1-AMINIUM OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF IN THE TREATMENT OF ATHEROSCLEROSIS
LOZA, EINARS, DAMBROVA, MAIJA, KUKA, JANIS, LIEPINS, EDGARS, GRINBERGA, SOLVEIGA, KALVINS, IVARS, GUSTINA, DAINA, STONANS, ILMARS, LOLA, DAINA, VILSKERSTS, REINIS, MAKRECKA, MARINA, PUGOVICS, OSVALDS, ANDRIANOVS, VIKTORS
Year of Publication 26.11.2019
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Year of Publication 26.11.2019
Patent
USE OF 3-CARBOXY-N-ETHYL-N,N-DIMETHYLPROPAN-1-AMINIUM SALTS IN THE TREATMENT OF CARDIOVASCULAR DISEASE
LOZA, EINARS, LOLA, DAINA, DAMBROVA, MAIJA, LIEPINS, EDGARS, KUKA, JANIS, VILSKERSTS, REINIS, GRINBERGA, SOLVEIGA, PUGOVICS, OSVALDS, KALVINS, IVARS, STONANS, ILMARS
Year of Publication 02.10.2018
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Year of Publication 02.10.2018
Patent
USE OF 3-CARBOXY-N-ETHYL-N,N-DIMETHYLPROPAN-1-AMINIUM SALTS IN THE TREATMENT OF CARDIOVASCULAR DISEASE
KALVINS Ivars, DAMBROVA Maija, LOLA Daina, LOZA Einars, STONANS IImars, VILSKERSTS Reinis, GRINBERGA Solveiga, PUGOVICS Osvalds, KUKA Janis, LIEPINS Edgars
Year of Publication 22.03.2018
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Year of Publication 22.03.2018
Patent
USE OF 3-CARBOXY-N-ETHYL-N,N-DIMETHYLPROPAN-1-AMINIUM SALTS IN THE TREATMENT OF CARDIOVASCULAR DISEASE
KUKA, Janis, PUGOVICS, Osvalds, STONANS, Ilmars, DAMBROVA, Maija, KALVINS, Ivars, GRINBERGA, Solveiga, LIEPINS, Edgars, LOLA, Daina, LOZA, Einars, VILSKERSTS, Reinis
Year of Publication 29.05.2017
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Year of Publication 29.05.2017
Patent
USE OF 3-CARBOXY-N-ETHYL-N,N-DIMETHYLPROPAN-1-AMINIUM SALTS IN THE TREATMENT OF CARDIOVASCULAR DISEASE
LOZA EINARS, KALVINS IVARS, LIEPINS EDGARS, PUGOVICS OSVALDS, GRINBERGA SOLVEIGA, KUKA JANIS, DAMBROVA MAIJA, LOLA DAINA, STONANS ILMARS, VILSKERSTS REINIS
Year of Publication 28.04.2017
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Year of Publication 28.04.2017
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USE OF 3-CARBOXY-N-ETHYL-N,N-DIMETHYLPROPAN-1-AMINIUM SALTS IN THE TREATMENT OF CARDIOVASCULAR DISEASE
LOZA, EINARS, DAMBROVA, MAIJA, LOLA, DAINA, LIEPINS, EDGARS, KUKA, JANIS, VILSKERSTS, REINIS, GRINBERGA, SOLVEIGA, PUGOVICS, OSVALDS, KALVINS, IVARS, STONANS, ILMARS
Year of Publication 30.12.2016
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Year of Publication 30.12.2016
Patent
USE OF 3-CARBOXY-N-ETHYL-N,N-DIMETHYLPROPAN-1-AMINIUM SALTS IN THE TREATMENT OF CARDIOVASCULAR DISEASE
Stonans, Ilmars, Lola, Daina, Kuka, Janis, Vilskersts, Reinis, Loza, Einars, Pugovics, Osvalds, Kalvins, Ivars, Liepins, Edgars, Dambrova, Maija, Grinberga, Solveiga
Year of Publication 21.10.2016
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Year of Publication 21.10.2016
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USE OF 3-CARBOXY-N-ETHYL-N,N-DIMETHYLPROPAN-1-AMINIUM SALTS IN THE TREATMENT OF CARDIOVASCULAR DISEASE
KALVINS Ivars, DAMBROVA Maija, LOLA Daina, LOZA Einars, GRINBERGA Solveiga, VILSKERSTS Reinis, STONANS Ilmars, PUGOVICS Osvalds, KUKA Janis, LIEPINS Edgars
Year of Publication 30.09.2016
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Year of Publication 30.09.2016
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USE OF 3-CARBOXY-N-ETHYL-N,N-DIMETHYLPROPAN-1-AMINIUM SALTS IN THE TREATMENT OF CARDIOVASCULAR DISEASE
KUKA, Janis, PUGOVICS, Osvalds, STONANS, Ilmars, DAMBROVA, Maija, KALVINS, Ivars, GRINBERGA, Solveiga, LIEPINS, Edgars, LOLA, Daina, LOZA, Einars, VILSKERSTS, Reinis
Year of Publication 12.09.2016
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Year of Publication 12.09.2016
Patent
ANVENDELSE AF 3-CARBOXY-N-ETHYL-N,N-DIMETHYLPROPAN-1-AMINIUMSALTE I BEHANDLINGEN AF HJERTEKARSYGDOM
KUKA, Janis, PUGOVICS, Osvalds, STONANS, Ilmars, DAMBROVA, Maija, KALVINS, Ivars, GRINBERGA, Solveiga, LIEPINS, Edgars, LOLA, Daina, LOZA, Einars, VILSKERSTS, Reinis
Year of Publication 29.08.2016
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Year of Publication 29.08.2016
Patent