A nanoluciferase SARS-CoV-2 for rapid neutralization testing and screening of anti-infective drugs for COVID-19
Xie, Xuping, Muruato, Antonio E., Zhang, Xianwen, Lokugamage, Kumari G., Fontes-Garfias, Camila R., Zou, Jing, Liu, Jianying, Ren, Ping, Balakrishnan, Mini, Cihlar, Tomas, Tseng, Chien-Te K., Makino, Shinji, Menachery, Vineet D., Bilello, John P., Shi, Pei-Yong
Published in Nature communications (15.10.2020)
Published in Nature communications (15.10.2020)
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Nucleocapsid mutations in SARS-CoV-2 augment replication and pathogenesis
Johnson, Bryan A, Zhou, Yiyang, Lokugamage, Kumari G, Vu, Michelle N, Bopp, Nathen, Crocquet-Valdes, Patricia A, Kalveram, Birte, Schindewolf, Craig, Liu, Yang, Scharton, Dionna, Plante, Jessica A, Xie, Xuping, Aguilar, Patricia, Weaver, Scott C, Shi, Pei-Yong, Walker, David H, Routh, Andrew L, Plante, Kenneth S, Menachery, Vineet D
Published in PLoS pathogens (01.06.2022)
Published in PLoS pathogens (01.06.2022)
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Loss of furin cleavage site attenuates SARS-CoV-2 pathogenesis
Johnson, Bryan A., Xie, Xuping, Bailey, Adam L., Kalveram, Birte, Lokugamage, Kumari G., Muruato, Antonio, Zou, Jing, Zhang, Xianwen, Juelich, Terry, Smith, Jennifer K., Zhang, Lihong, Bopp, Nathen, Schindewolf, Craig, Vu, Michelle, Vanderheiden, Abigail, Winkler, Emma S., Swetnam, Daniele, Plante, Jessica A., Aguilar, Patricia, Plante, Kenneth S., Popov, Vsevolod, Lee, Benhur, Weaver, Scott C., Suthar, Mehul S., Routh, Andrew L., Ren, Ping, Ku, Zhiqiang, An, Zhiqiang, Debbink, Kari, Diamond, Michael S., Shi, Pei-Yong, Freiberg, Alexander N., Menachery, Vineet D.
Published in Nature (London) (11.03.2021)
Published in Nature (London) (11.03.2021)
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Severe Acute Respiratory Syndrome Coronavirus 2 from Patient with Coronavirus Disease, United States
Harcourt, Jennifer, Tamin, Azaibi, Lu, Xiaoyan, Kamili, Shifaq, Sakthivel, Senthil K, Murray, Janna, Queen, Krista, Tao, Ying, Paden, Clinton R, Zhang, Jing, Li, Yan, Uehara, Anna, Wang, Haibin, Goldsmith, Cynthia, Bullock, Hannah A, Wang, Lijuan, Whitaker, Brett, Lynch, Brian, Gautam, Rashi, Schindewolf, Craig, Lokugamage, Kumari G, Scharton, Dionna, Plante, Jessica A, Mirchandani, Divya, Widen, Steven G, Narayanan, Krishna, Makino, Shinji, Ksiazek, Thomas G, Plante, Kenneth S, Weaver, Scott C, Lindstrom, Stephen, Tong, Suxiang, Menachery, Vineet D, Thornburg, Natalie J
Published in Emerging infectious diseases (01.06.2020)
Published in Emerging infectious diseases (01.06.2020)
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SARS coronavirus nsp1 protein induces template-dependent endonucleolytic cleavage of mRNAs: viral mRNAs are resistant to nsp1-induced RNA cleavage
Huang, Cheng, Lokugamage, Kumari G, Rozovics, Janet M, Narayanan, Krishna, Semler, Bert L, Makino, Shinji
Published in PLoS pathogens (01.12.2011)
Published in PLoS pathogens (01.12.2011)
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Spike mutation D614G alters SARS-CoV-2 fitness
Plante, Jessica A., Liu, Yang, Liu, Jianying, Xia, Hongjie, Johnson, Bryan A., Lokugamage, Kumari G., Zhang, Xianwen, Muruato, Antonio E., Zou, Jing, Fontes-Garfias, Camila R., Mirchandani, Divya, Scharton, Dionna, Bilello, John P., Ku, Zhiqiang, An, Zhiqiang, Kalveram, Birte, Freiberg, Alexander N., Menachery, Vineet D., Xie, Xuping, Plante, Kenneth S., Weaver, Scott C., Shi, Pei-Yong
Published in Nature (London) (01.04.2021)
Published in Nature (London) (01.04.2021)
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Journal Article
An Infectious cDNA Clone of SARS-CoV-2
Xie, Xuping, Muruato, Antonio, Lokugamage, Kumari G., Narayanan, Krishna, Zhang, Xianwen, Zou, Jing, Liu, Jianying, Schindewolf, Craig, Bopp, Nathen E., Aguilar, Patricia V., Plante, Kenneth S., Weaver, Scott C., Makino, Shinji, LeDuc, James W., Menachery, Vineet D., Shi, Pei-Yong
Published in Cell Host & Microbe (13.05.2020)
Published in Cell Host & Microbe (13.05.2020)
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Severe Acute Respiratory Syndrome Coronavirus Protein nsp1 Is a Novel Eukaryotic Translation Inhibitor That Represses Multiple Steps of Translation Initiation
Lokugamage, Kumari G, Narayanan, Krishna, Huang, Cheng, Makino, Shinji
Published in Journal of Virology (01.12.2012)
Published in Journal of Virology (01.12.2012)
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Middle East Respiratory Syndrome Coronavirus nsp1 Inhibits Host Gene Expression by Selectively Targeting mRNAs Transcribed in the Nucleus while Sparing mRNAs of Cytoplasmic Origin
Lokugamage, Kumari G, Narayanan, Krishna, Nakagawa, Keisuke, Terasaki, Kaori, Ramirez, Sydney I, Tseng, Chien-Te K, Makino, Shinji
Published in Journal of virology (01.11.2015)
Published in Journal of virology (01.11.2015)
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Author Correction: A nanoluciferase SARS-CoV-2 for rapid neutralization testing and screening of anti-infective drugs for COVID-19
Xie, Xuping, Muruato, Antonio E., Zhang, Xianwen, Lokugamage, Kumari G., Fontes-Garfias, Camila R., Zou, Jing, Liu, Jianying, Ren, Ping, Balakrishnan, Mini, Cihlar, Tomas, Tseng, Chien-Te K., Makino, Shinji, Menachery, Vineet D., Bilello, John P., Shi, Pei-Yong
Published in Nature communications (21.06.2021)
Published in Nature communications (21.06.2021)
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Journal Article
Engineering SARS-CoV-2 using a reverse genetic system
Xie, Xuping, Lokugamage, Kumari G., Zhang, Xianwen, Vu, Michelle N., Muruato, Antonio E., Menachery, Vineet D., Shi, Pei-Yong
Published in Nature protocols (01.03.2021)
Published in Nature protocols (01.03.2021)
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Mouse-adapted SARS-CoV-2 protects animals from lethal SARS-CoV challenge
Muruato, Antonio, Vu, Michelle N, Johnson, Bryan A, Davis-Gardner, Meredith E, Vanderheiden, Abigail, Lokugamage, Kumari, Schindewolf, Craig, Crocquet-Valdes, Patricia A, Langsjoen, Rose M, Plante, Jessica A, Plante, Kenneth S, Weaver, Scott C, Debbink, Kari, Routh, Andrew L, Walker, David, Suthar, Mehul S, Shi, Pei-Yong, Xie, Xuping, Menachery, Vineet D
Published in PLoS biology (01.11.2021)
Published in PLoS biology (01.11.2021)
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Severe Acute Respiratory Syndrome Coronavirus nsp1 Protein Suppresses Host Gene Expression by Promoting Host mRNA Degradation
Kamitani, Wataru, Narayanan, Krishna, Huang, Cheng, Lokugamage, Kumari, Ikegami, Tetsuro, Ito, Naoto, Kubo, Hideyuki, Makino, Shinji
Published in Proceedings of the National Academy of Sciences - PNAS (22.08.2006)
Published in Proceedings of the National Academy of Sciences - PNAS (22.08.2006)
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QTQTN motif upstream of the furin-cleavage site plays a key role in SARS-CoV-2 infection and pathogenesis
Vu, Michelle N, Lokugamage, Kumari G, Plante, Jessica A, Scharton, Dionna, Bailey, Aaron O, Sotcheff, Stephanea, Swetnam, Daniele M, Johnson, Bryan A, Schindewolf, Craig, Alvarado, R Elias, Crocquet-Valdes, Patricia A, Debbink, Kari, Weaver, Scott C, Walker, David H, Russell, William K, Routh, Andrew L, Plante, Kenneth S, Menachery, Vineet D
Published in Proceedings of the National Academy of Sciences - PNAS (09.08.2022)
Published in Proceedings of the National Academy of Sciences - PNAS (09.08.2022)
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Severe Acute Respiratory Syndrome Coronavirus nsp1 Suppresses Host Gene Expression, Including That of Type I Interferon, in Infected Cells
Narayanan, Krishna, Huang, Cheng, Lokugamage, Kumari, Kamitani, Wataru, Ikegami, Tetsuro, Tseng, Chien-Te K, Makino, Shinji
Published in Journal of Virology (01.05.2008)
Published in Journal of Virology (01.05.2008)
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Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication and pathogenicity
Yang, Zemin, Johnson, Bryan A., Meliopoulos, Victoria A., Ju, Xiaohui, Zhang, Peipei, Hughes, Michael P., Wu, Jinjun, Koreski, Kaitlin P., Clary, Jemma E., Chang, Ti-Cheng, Wu, Gang, Hixon, Jeff, Duffner, Jay, Wong, Kathy, Lemieux, Rene, Lokugamage, Kumari G., Alvarado, R. Elias, Crocquet-Valdes, Patricia A., Walker, David H., Plante, Kenneth S., Plante, Jessica A., Weaver, Scott C., Kim, Hong Joo, Meyers, Rachel, Schultz-Cherry, Stacey, Ding, Qiang, Menachery, Vineet D., Taylor, J. Paul
Published in Cell reports (Cambridge) (26.03.2024)
Published in Cell reports (Cambridge) (26.03.2024)
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