4-[3-(4-Cyclopropanecarbonylpiperazine-1-carbonyl)-4-fluorobenzyl]-2H-phthalazin-1-one: A Novel Bioavailable Inhibitor of Poly(ADP-ribose) Polymerase-1
Menear, Keith A, Adcock, Claire, Boulter, Robert, Cockcroft, Xiao-ling, Copsey, Louise, Cranston, Aaron, Dillon, Krystyna J, Drzewiecki, Jan, Garman, Sheila, Gomez, Sylvie, Javaid, Hashim, Kerrigan, Frank, Knights, Charlotte, Lau, Alan, Loh, Vincent M, Matthews, Ian T. W, Moore, Stephen, O’Connor, Mark J, Smith, Graeme C. M, Martin, Niall M. B
Published in Journal of medicinal chemistry (23.10.2008)
Published in Journal of medicinal chemistry (23.10.2008)
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Phthalazinones. Part 1: The design and synthesis of a novel series of potent inhibitors of poly(ADP-ribose)polymerase
Loh, Vincent M., Cockcroft, Xiao-ling, Dillon, Krystyna J., Dixon, Lesley, Drzewiecki, Jan, Eversley, Penny J., Gomez, Sylvie, Hoare, Janet, Kerrigan, Frank, Matthews, Ian T.W., Menear, Keith A., Martin, Niall M.B., Newton, Roger F., Paul, Jane, Smith, Graeme C.M., Vile, Julia, Whittle, Alan J.
Published in Bioorganic & medicinal chemistry letters (02.05.2005)
Published in Bioorganic & medicinal chemistry letters (02.05.2005)
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Phthalazinones 2: Optimisation and synthesis of novel potent inhibitors of poly(ADP-ribose)polymerase
Cockcroft, Xiao-ling, Dillon, Krystyna J., Dixon, Lesley, Drzewiecki, Jan, Kerrigan, Frank, Loh, Vincent M., Martin, Niall M.B., Menear, Keith A., Smith, Graeme C.M.
Published in Bioorganic & medicinal chemistry letters (15.02.2006)
Published in Bioorganic & medicinal chemistry letters (15.02.2006)
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Journal Article
4-[3-(4-Cyclopropanecarbonylpiperazine-1-carbonyl)-4-fluorobenzyl]-2 H -phthalazin-1-one: A Novel Bioavailable Inhibitor of Poly(ADP-ribose) Polymerase-1
Menear, Keith A., Adcock, Claire, Boulter, Robert, Cockcroft, Xiao-ling, Copsey, Louise, Cranston, Aaron, Dillon, Krystyna J., Drzewiecki, Jan, Garman, Sheila, Gomez, Sylvie, Javaid, Hashim, Kerrigan, Frank, Knights, Charlotte, Lau, Alan, Loh, Vincent M., Matthews, Ian T. W., Moore, Stephen, O’Connor, Mark J., Smith, Graeme C. M., Martin, Niall M. B.
Published in Journal of medicinal chemistry (23.10.2008)
Published in Journal of medicinal chemistry (23.10.2008)
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DHPMP: a novel group I specific metabotropic glutamate receptor agonist
Boyd, E.Andrew, Alexander, Stephen P.H., Kendall, David A., Loh, Vincent M.
Published in Bioorganic & medicinal chemistry letters (03.09.1996)
Published in Bioorganic & medicinal chemistry letters (03.09.1996)
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compostos derivados de ftalazinona, seu uso e composição farmacêutica compreendendo os mesmos
Niall Morrison Barr Martin, Xiao-Ling Fan Cockcroft, Stephen Philip Jackson, Alan Ashworth, Keith Allan Menear, Ian Timothy Williams Matthews, Graeme Cameron Murray Smith, Vincent M. Loh Junior, Frank Kerrigan
Year of Publication 25.05.2021
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Year of Publication 25.05.2021
Patent
compostos derivados de ftalazinona, seu uso e composição farmacêutica compreendendo os mesmos
Niall Morrison Barr Martin, Xiao-Ling Fan Cockcroft, Stephen Philip Jackson, Alan Ashworth, Keith Allan Menear, Ian Timothy Williams Matthews, Graeme Cameron Murray Smith, Vincent M. Loh Junior, Frank Kerrigan
Year of Publication 26.12.2018
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Year of Publication 26.12.2018
Patent
Phthalazinones 2: Optimization and Synthesis of Novel Potent Inhibitors of Poly(ADP-Ribose)polymerase
Cockcroft, Xiao-ling, Dillon, Krystyna J., Dixon, Lesley, Drzewiecki, Jan, Kerrigan, Frank, Loh, Vincent M. Jr, Martin, Niall M. B., Menear, Keith A., Smith, Graeme C. M.
Published in ChemInform (23.05.2006)
Published in ChemInform (23.05.2006)
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