Angiotensin II-dependent TGF-[Beta] signaling contributes to Loeys-Dietz syndrome vascular pathogenesis
Gallo, Elena M, Loch, David C, Habashi, Jennifer P, Calderon, Juan F, Chen, Yichun, Bedja, Djahida, van Erp, Christel, Gerber, Elizabeth E, Parker, Sarah J, Sauls, Kimberly, Judge, Daniel P, Cooke, Sara K, Lindsay, Mark E, Rouf, Rosanne, Myers, Loretha, Rhys, Colette M Ap, Kent, Kathleen C, Norris, Russell A, Huso, David L, Dietz, Harry C
Published in The Journal of clinical investigation (02.01.2014)
Published in The Journal of clinical investigation (02.01.2014)
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Journal Article
Angiotensin II-dependent TGF-β signaling contributes to Loeys-Dietz syndrome vascular pathogenesis
Gallo, Elena M, Loch, David C, Habashi, Jennifer P, Calderon, Juan F, Chen, Yichun, Bedja, Djahida, van Erp, Christel, Gerber, Elizabeth E, Parker, Sarah J, Sauls, Kimberly, Judge, Daniel P, Cooke, Sara K, Lindsay, Mark E, Rouf, Rosanne, Myers, Loretha, ap Rhys, Colette M, Kent, Kathleen C, Norris, Russell A, Huso, David L, Dietz, Harry C
Published in The Journal of clinical investigation (01.01.2014)
Published in The Journal of clinical investigation (01.01.2014)
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Journal Article
The N550K/H Mutations in FGFR2 Confer Differential Resistance to PD173074, Dovitinib, and Ponatinib ATP-Competitive Inhibitors
Byron, Sara A, Chen, Huaibin, Wortmann, Andreas, Loch, David, Gartside, Michael G, Dehkhoda, Farhad, Blais, Steven P, Neubert, Thomas A, Mohammadi, Moosa, Pollock, Pamela M
Published in Neoplasia (New York, N.Y.) (01.08.2013)
Published in Neoplasia (New York, N.Y.) (01.08.2013)
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Sensitivity to the MEK inhibitor E6201 in melanoma cells is associated with mutant BRAF and wildtype PTEN status
Byron, Sara A, Loch, David C, Wellens, Candice L, Wortmann, Andreas, Wu, Jiayi, Wang, John, Nomoto, Kenichi, Pollock, Pamela M
Published in Molecular cancer (05.10.2012)
Published in Molecular cancer (05.10.2012)
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Journal Article
p38 MAPK Is an Early Determinant of Promiscuous Smad2/3 Signaling in the Aortas of Fibrillin-1 (Fbn1)-null Mice
Carta, Luca, Smaldone, Silvia, Zilberberg, Lior, Loch, David, Dietz, Harry C., Rifkin, Daniel B., Ramirez, Francesco
Published in The Journal of biological chemistry (27.02.2009)
Published in The Journal of biological chemistry (27.02.2009)
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Journal Article
Arachidonic Acid Metabolism as a Potential Mediator of Cardiac Fibrosis Associated with Inflammation
Levick, Scott P, Loch, David C, Taylor, Stephen M, Janicki, Joseph S
Published in Journal of Immunology (15.01.2007)
Published in Journal of Immunology (15.01.2007)
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Timeline of cardiac dystrophy in 3-18-month-old MDX mice
Van Erp, Christel, Loch, David, Laws, Nicola, Trebbin, Andrea, Hoey, Andrew J.
Published in Muscle & nerve (01.10.2010)
Published in Muscle & nerve (01.10.2010)
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Journal Article
Circulating Transforming Growth Factor-β in Marfan Syndrome
MATT, Peter, SCHOENHOFF, Florian, LOEYS, Bart, HUSO, David L, MCDONNELL, Nazli B, VAN EYK, Jennifer E, DIETZ, Harry C, HABASHI, Jennifer, HOLM, Tammy, VAN ERP, Christel, LOCH, David, CARLSON, Olga D, GRISWOLD, Benjamin F, QIN FU, DE BACKER, Julie
Published in Circulation (New York, N.Y.) (11.08.2009)
Published in Circulation (New York, N.Y.) (11.08.2009)
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Abstract LB-B31: FGFR inhibition in endometrial cancer induces caspase-independent cell death that can be augmented with ABT-737
Packer, Leisl, Byron, Sara, Stehbens, Samantha, Bonazzi, Vanessa, Loch, David, Wortmann, Andreas, Gartside, Mike, Waterhouse, Nigel, Gunter, Jennifer, Pollock, Pamela M.
Published in Molecular cancer therapeutics (01.01.2018)
Published in Molecular cancer therapeutics (01.01.2018)
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Abstract 1715: Elucidating mechanisms of resistance to FGFR inhibitors in endometrial cancer
Packer, Leisl M., Byron, Sara, Loch, David, Dehkhoda, Farhad, Wortmann, Andreas, Geng, Xinyan, Nones, Katia, Grimmond, Sean, Pearson, John, Waddell, Nic, Pollock, Pamela
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
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Abstract A61: Profile of Ponatinib, BGJ398, AZ4547 and DCC-2036 against FGFR2 Mutations identified in a Dovitinib Resistance BaF3 Screen
Loch, David, Byron, Sara, Wortman, Andreas, Chen, Huaibin, Mohammadi, Moosa, Pollock, Pamela
Published in Clinical cancer research (15.05.2012)
Published in Clinical cancer research (15.05.2012)
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Journal Article
The N550K/H Mutations in FGFR2 Confer Differential Resistance to PD173074, Dovitinib, and Ponatinib ATP-Competitive Inhibitors12
Byron, Sara A, Chen, Huaibin, Wortmann, Andreas, Loch, David, Gartside, Michael G, Dehkhoda, Farhad, Blais, Steven P, Neubert, Thomas A, Mohammadi, Moosa, Pollock, Pamela M
Published in Neoplasia (New York, N.Y.) (01.08.2013)
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Published in Neoplasia (New York, N.Y.) (01.08.2013)
Journal Article
Antifibrotic Activity of an Inhibitor of Group IIA Secretory Phospholipase A2 in Young Spontaneously Hypertensive Rats
Levick, Scott, Loch, David, Rolfe, Barbara, Reid, Robert C, Fairlie, David P, Taylor, Stephen M, Brown, Lindsay
Published in The Journal of immunology (1950) (01.06.2006)
Published in The Journal of immunology (1950) (01.06.2006)
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