Natural and synthetic saponin adjuvant QS-21 for vaccines against cancer
Ragupathi, Govind, Gardner, Jeffrey R, Livingston, Philip O, Gin, David Y
Published in Expert review of vaccines (01.04.2011)
Published in Expert review of vaccines (01.04.2011)
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Development of a minimal saponin vaccine adjuvant based on QS-21
Fernández-Tejada, Alberto, Chea, Eric K., George, Constantine, Pillarsetty, NagaVaraKishore, Gardner, Jeffrey R., Livingston, Philip O., Ragupathi, Govind, Lewis, Jason S., Tan, Derek S., Gin, David Y.
Published in Nature chemistry (01.07.2014)
Published in Nature chemistry (01.07.2014)
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Applying PET to broaden the diagnostic utility of the clinically validated CA19.9 serum biomarker for oncology
Viola-Villegas, Nerissa Therese, Rice, Samuel L, Carlin, Sean, Wu, Xiaohong, Evans, Michael J, Sevak, Kuntal K, Drobjnak, Marija, Ragupathi, Govind, Sawada, Ritsuko, Scholz, Wolfgang W, Livingston, Philip O, Lewis, Jason S
Published in Journal of Nuclear Medicine (01.11.2013)
Published in Journal of Nuclear Medicine (01.11.2013)
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A randomised phase II trial of a trivalent ganglioside vaccine targeting GM2, GD2 and GD3 combined with immunological adjuvant OPT-821 versus OPT-821 alone in metastatic sarcoma patients rendered disease-free by surgery
Rosenbaum, Evan, Chugh, Rashmi, Ryan, Christopher W., Agulnik, Mark, Milhem, Mohammed M., George, Suzanne, Jones, Robin L., Chmielowski, Bartosz, Van Tine, Brian A., Tawbi, Hussein, Elias, Anthony D., Read, William L., Budd, G. Thomas, Qin, Li-Xuan, Rodler, Eve T., Hirman, Joe, Weiden, Paul, Bennett, Cathryn M., Livingston, Philip O., Ragupathi, Govind, Hansen, David, D'Angelo, Sandra P., Tap, William D., Schwartz, Gary K., Maki, Robert G., Carvajal, Richard D.
Published in European journal of cancer (1990) (01.11.2022)
Published in European journal of cancer (1990) (01.11.2022)
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Synthesis and Preclinical Evaluation of QS-21 Variants Leading to Simplified Vaccine Adjuvants and Mechanistic Probes
Chea, Eric K, Fernández-Tejada, Alberto, Damani, Payal, Adams, Michelle M, Gardner, Jeffrey R, Livingston, Philip O, Ragupathi, Govind, Gin, David Y
Published in Journal of the American Chemical Society (15.08.2012)
Published in Journal of the American Chemical Society (15.08.2012)
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A High-Throughput O-Glycopeptide Discovery Platform for Seromic Profiling
Blixt, Ola, Cló, Emiliano, Nudelman, Aaron S, Sørensen, Kasper Kildegaard, Clausen, Thomas, Wandall, Hans H, Livingston, Philip O, Clausen, Henrik, Jensen, Knud J
Published in Journal of proteome research (01.10.2010)
Published in Journal of proteome research (01.10.2010)
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From Synthesis to Biologics: Preclinical Data on a Chemistry Derived Anticancer Vaccine
Zhu, Jianglong, Wan, Qian, Lee, Dongjoo, Yang, Guangbin, Spassova, Maria K, Ouerfelli, Ouathek, Ragupathi, Govind, Damani, Payal, Livingston, Philip O, Danishefsky, Samuel J
Published in Journal of the American Chemical Society (08.07.2009)
Published in Journal of the American Chemical Society (08.07.2009)
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Design and Synthesis of Potent Quillaja Saponin Vaccine Adjuvants
Adams, Michelle M, Damani, Payal, Perl, Nicholas R, Won, Annie, Hong, Feng, Livingston, Philip O, Ragupathi, Govind, Gin, David Y
Published in Journal of the American Chemical Society (17.02.2010)
Published in Journal of the American Chemical Society (17.02.2010)
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Abstract 4993: Novel fully human anti-GD2 monoclonal antibodies with potent therapeutic activity against neuroblastoma, sarcoma and melanoma
Ragupathi, Govind, Wu, Xiaohong, Sawada, Ritsuko, Livingston, Philip O., Scholz, Wolfgang W.
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Synthesis of QS-21-Xylose: Establishment of the Immunopotentiating Activity of Synthetic QS-21 Adjuvant with a Melanoma Vaccine
Deng, Kai, Adams, Michelle M, Damani, Payal, Livingston, Philip O, Ragupathi, Govind, Gin, David Y
Published in Angewandte Chemie (International ed.) (01.01.2008)
Published in Angewandte Chemie (International ed.) (01.01.2008)
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Design, synthesis, and immunologic evaluation of vaccine adjuvant conjugates based on QS-21 and tucaresol
Fernández-Tejada, Alberto, Chea, Eric K., George, Constantine, Gardner, Jeffrey R., Livingston, Philip O., Ragupathi, Govind, Tan, Derek S., Gin, David Y.
Published in Bioorganic & medicinal chemistry (01.11.2014)
Published in Bioorganic & medicinal chemistry (01.11.2014)
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Pilot Study of a Heptavalent Vaccine-Keyhole Limpet Hemocyanin Conjugate plus QS21 in Patients with Epithelial Ovarian, Fallopian Tube, or Peritoneal Cancer
SABBATINI, Paul J, RAGUPATHI, Govind, TEW, William P, KONNER, Jason, CLAUSEN, Henrik, ABU RUSTUM, Nadeem, DANSIHEFSKY, Samuel J, LIVINGSTON, Philip O, HOOD, Chandra, AGHAJANIAN, Carol A, JURETZKA, Margrit, LASONOS, Alexia, HENSLEY, Martee L, SPASSOVA, Maria K, OUERFELLI, Ouathek, SPRIGGS, David R
Published in Clinical cancer research (15.07.2007)
Published in Clinical cancer research (15.07.2007)
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Accelerated Tumor Growth Mediated by Sublytic Levels of Antibody-Induced Complement Activation Is Associated with Activation of the PI3K/AKT Survival Pathway
XIAOHONG WU, RAGUPATHI, Govind, PANAGEAS, Katherine, FENG HONG, LIVINGSTON, Philip O
Published in Clinical cancer research (01.09.2013)
Published in Clinical cancer research (01.09.2013)
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Biologics through Chemistry: Total Synthesis of a Proposed Dual-Acting Vaccine Targeting Ovarian Cancer by Orchestration of Oligosaccharide and Polypeptide Domains
Zhu, Jianglong, Wan, Qian, Ragupathi, Govind, George, Constantine M, Livingston, Philip O, Danishefsky, Samuel J
Published in Journal of the American Chemical Society (25.03.2009)
Published in Journal of the American Chemical Society (25.03.2009)
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Preparation and Evaluation of Unimolecular Pentavalent and Hexavalent Antigenic Constructs Targeting Prostate and Breast Cancer: A Synthetic Route to Anticancer Vaccine Candidates
Ragupathi, Govind, Koide, Fusataka, Livingston, Philip O, Cho, Young Shin, Endo, Atsushi, Wan, Qian, Spassova, Maria K, Keding, Stacy J, Allen, Jennifer, Ouerfelli, Ouathek, Wilson, Rebecca M, Danishefsky, Samuel J
Published in Journal of the American Chemical Society (01.03.2006)
Published in Journal of the American Chemical Society (01.03.2006)
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Selective CD4+ Lymphopenia in Melanoma Patients Treated With Temozolomide: A Toxicity With Therapeutic Implications
SU, Y. B, SOHN, Sejean, KROWN, Susan E, LIVINGSTON, Philip O, WOLCHOK, Jedd D, QUINN, Carolyn, WILLIAMS, Linda, FOSTER, Theresa, SEPKOWITZ, Kent A, CHAPMAN, Paul B
Published in Journal of clinical oncology (15.02.2004)
Published in Journal of clinical oncology (15.02.2004)
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Immunization with N-propionyl polysialic acid–KLH conjugate in patients with small cell lung cancer is safe and induces IgM antibodies reactive with SCLC cells and bactericidal against group B meningococci
Krug, Lee M., Ragupathi, Govind, Hood, Chandra, George, Constantine, Hong, Feng, Shen, Ronglai, Abrey, Lauren, Jennings, Harold J., Kris, Mark G., Livingston, Philip O.
Published in Cancer Immunology, Immunotherapy (01.01.2012)
Published in Cancer Immunology, Immunotherapy (01.01.2012)
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Immunization of High-Risk Breast Cancer Patients with Clustered sTn-KLH Conjugate plus the Immunologic Adjuvant QS-21
GILEWSKI, Teresa A, RAGUPATHI, Govind, HOUGHTON, Alan N, LIVINGSTON, Philip O, DICKLER, Maura, POWELL, Shemeeakah, BHUTA, Sonal, PANAGEAS, Kathy, RAO KOGANTY, R, CHIN-ENG, Jeannette, HUDIS, Clifford, NORTON, Larry
Published in Clinical cancer research (15.05.2007)
Published in Clinical cancer research (15.05.2007)
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The known immunologically active components of Astragalus account for only a small proportion of the immunological adjuvant activity when combined with conjugate vaccines
Hong, Feng, Xiao, Weilie, Ragupathi, Govind, Lau, Clara B S, Leung, Ping Chung, Yeung, K Simon, George, Constantine, Cassileth, Barrie, Kennelly, Edward, Livingston, Philip O
Published in Planta medica (01.05.2011)
Published in Planta medica (01.05.2011)
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