Synthesis and Biological Evaluation of Aryl-phospho-indole as Novel HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors
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Published in Journal of medicinal chemistry (13.01.2011)
Published in Journal of medicinal chemistry (13.01.2011)
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Identification of a lipid kinase as a host factor involved in hepatitis C virus RNA replication
Vaillancourt, Frédéric H, Pilote, Louise, Cartier, Mireille, Lippens, Julie, Liuzzi, Michel, Bethell, Richard C, Cordingley, Michael G, Kukolj, George
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Published in Bioorganic & medicinal chemistry letters (15.12.2012)
Published in Bioorganic & medicinal chemistry letters (15.12.2012)
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Structure-based design of a novel series of azetidine inhibitors of the hepatitis C virus NS3/4A serine protease
Parsy, Christophe, Alexandre, François-René, Brandt, Guillaume, Caillet, Catherine, Cappelle, Sylvie, Chaves, Dominique, Convard, Thierry, Derock, Michel, Gloux, Damien, Griffon, Yann, Lallos, Lisa, Leroy, Frédéric, Liuzzi, Michel, Loi, Anna-Giulia, Moulat, Laure, Musiu, Chiara, Rahali, Houcine, Roques, Virginie, Seifer, Maria, Standring, David, Surleraux, Dominique
Published in Bioorganic & medicinal chemistry letters (15.09.2014)
Published in Bioorganic & medicinal chemistry letters (15.09.2014)
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Inhibitors of Respiratory Syncytial Virus Replication Target Cotranscriptional mRNA Guanylylation by Viral RNA-Dependent RNA Polymerase
LIUZZI, Michel, MASON, Stephen W, MASSARIOL, Marie-Josée, DO, Florence, WHITEHEAD, Paul, LAMARRE, Lyne, SCOUTEN, Erika, BORDELEAU, Josée, LANDRY, Serge, RANCOURT, Jean, FAZAL, Gulrez, SIMONEAU, Bruno, CARTIER, Mireille, LAWETZ, Carol, MCCOLLUM, Robert S, DANSEREAU, Nathalie, BOLGER, Gordon, LAPEYRE, Nicole, GAUDETTE, Yvon, LAGACE, Lisette
Published in Journal of Virology (01.10.2005)
Published in Journal of Virology (01.10.2005)
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High content screening of a kinase-focused library reveals compounds broadly-active against dengue viruses
Cruz, Deu John M, Koishi, Andrea Cristine, Taniguchi, Juliana Bosso, Li, Xiaolan, Milan Bonotto, Rafaela, No, Joo Hwan, Kim, Keum Hyun, Baek, Sungmin, Kim, Hee Young, Windisch, Marc Peter, Pamplona Mosimann, Ana Luiza, de Borba, Luana, Liuzzi, Michel, Hansen, Michael Adsetts Edberg, Duarte dos Santos, Claudia Nunes, Freitas-Junior, Lucio Holanda
Published in PLoS neglected tropical diseases (01.02.2013)
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Interaction between Human Respiratory Syncytial Virus (RSV) M2-1 and P Proteins Is Required for Reconstitution of M2-1-Dependent RSV Minigenome Activity
Mason, Stephen W, Aberg, Erika, Lawetz, Carol, DeLong, Rachel, Whitehead, Paul, Liuzzi, Michel
Published in Journal of Virology (01.10.2003)
Published in Journal of Virology (01.10.2003)
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Oral Bioavailability and In Vivo Efficacy of the Helicase-Primase Inhibitor BILS 45 BS against Acyclovir-Resistant Herpes Simplex Virus Type 1
JIANMIN DUAN, LIUZZI, Michel, PARIS, William, LIARD, Francine, BROWNE, Abigail, DANSEREAU, Nathalie, SIMONEAU, Bruno, FAUCHER, Anne-Marie, CORDINGLEY, Michael G
Published in Antimicrobial Agents and Chemotherapy (01.06.2003)
Published in Antimicrobial Agents and Chemotherapy (01.06.2003)
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Antiviral Activity of a Selective Ribonucleotide Reductase Inhibitor against Acyclovir-Resistant Herpes Simplex Virus Type 1 In Vivo
DUAN, J, LIUZZI, M, PARIS, W, LAMBERT, M, LAWETZ, C, MOSS, N, JARAMILLO, J, GAUTHIER, J, DEZIEL, R, CORDINGLEY, M. G
Published in Antimicrobial Agents and Chemotherapy (01.07.1998)
Published in Antimicrobial Agents and Chemotherapy (01.07.1998)
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Discovery of the Aryl-phospho-indole IDX899, a Highly Potent Anti-HIV Non-nucleoside Reverse Transcriptase Inhibitor
Dousson, Cyril, Alexandre, François-René, Amador, Agnès, Bonaric, Séverine, Bot, Stéphanie, Caillet, Catherine, Convard, Thierry, da Costa, Daniel, Lioure, Marie-Pierre, Roland, Arlène, Rosinovsky, Elodie, Maldonado, Sébastien, Parsy, Christophe, Trochet, Christophe, Storer, Richard, Stewart, Alistair, Wang, Jingyang, Mayes, Benjamin A, Musiu, Chiara, Poddesu, Barbara, Vargiu, Luana, Liuzzi, Michel, Moussa, Adel, Jakubik, Jocelyn, Hubbard, Luke, Seifer, Maria, Standring, David
Published in Journal of medicinal chemistry (10.03.2016)
Published in Journal of medicinal chemistry (10.03.2016)
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Discovery of Carbohybrid-Based 2‑Aminopyrimidine Analogues As a New Class of Rapid-Acting Antimalarial Agents Using Image-Based Cytological Profiling Assay
Lee, Sukjun, Lim, Donghyun, Lee, Eunyoung, Lee, Nakyung, Lee, Hong-gun, Cechetto, Jonathan, Liuzzi, Michel, Freitas-Junior, Lucio H, Song, Jin Sook, Bae, Myung Ae, Oh, Sangmi, Ayong, Lawrence, Park, Seung Bum
Published in Journal of medicinal chemistry (11.09.2014)
Published in Journal of medicinal chemistry (11.09.2014)
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A novel 3,4-dihydropyrimidin-2(1H)-one: HIV-1 replication inhibitors with improved metabolic stability
Kim, Junwon, Ok, Taedong, Park, Changmin, So, Wonyoung, Jo, Mina, Kim, Youngmi, Seo, Minjung, Lee, Doohyun, Jo, Suyeon, Ko, Yoonae, Choi, Inhee, Park, Youngsam, Yoon, Jaewan, Ju, Moon Kyeong, Ahn, JiYe, Kim, Junghwan, Han, Sung-Jun, Kim, Tae-Hee, Cechetto, Jonathan, Nam, Jiyoun, Liuzzi, Michel, Sommer, Peter, No, Zaesung
Published in Bioorganic & medicinal chemistry letters (01.04.2012)
Published in Bioorganic & medicinal chemistry letters (01.04.2012)
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Discovery and structural diversity of the hepatitis C virus NS3/4A serine protease inhibitor series leading to clinical candidate IDX320
Parsy, Christophe C., Alexandre, François-René, Bidau, Valérie, Bonnaterre, Florence, Brandt, Guillaume, Caillet, Catherine, Cappelle, Sylvie, Chaves, Dominique, Convard, Thierry, Derock, Michel, Gloux, Damien, Griffon, Yann, Lallos, Lisa B., Leroy, Frederic, Liuzzi, Michel, Loi, Anna-Giulia, Moulat, Laure, Chiara, Musiu, Rahali, Houcine, Roques, Virginie, Rosinovsky, Elodie, Savin, Simon, Seifer, Maria, Standring, David, Surleraux, Dominique
Published in Bioorganic & medicinal chemistry letters (15.11.2015)
Published in Bioorganic & medicinal chemistry letters (15.11.2015)
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Discovery of benzophosphadiazine drug candidate IDX375: A novel hepatitis C allosteric NS5B RdRp inhibitor
Paparin, Jean-Laurent, Amador, Agnès, Badaroux, Eric, Bot, Stéphanie, Caillet, Catherine, Convard, Thierry, Da Costa, Daniel, Dukhan, David, Griffe, Ludovic, Griffon, Jean-François, LaColla, Massimiliano, Leroy, Frédéric, Liuzzi, Michel, Giulia Loi, Anna, McCarville, Joe, Mascia, Valeria, Milhau, Julien, Onidi, Loredana, Pierra, Claire, Rahali, Rachid, Rosinosky, Elodie, Sais, Efisio, Seifer, Maria, Surleraux, Dominique, Standring, David, Dousson, Cyril B.
Published in Bioorganic & medicinal chemistry letters (01.06.2017)
Published in Bioorganic & medicinal chemistry letters (01.06.2017)
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Synthesis of potent and broad genotypically active NS5B HCV non-nucleoside inhibitors binding to the thumb domain allosteric site 2 of the viral polymerase
Pierra Rouvière, Claire, Amador, Agnès, Badaroux, Eric, Convard, Thierry, Da Costa, Daniel, Dukhan, David, Griffe, Ludovic, Griffon, Jean-François, LaColla, Massimiliano, Leroy, Frédéric, Liuzzi, Michel, Loi, Anna Giulia, McCarville, Joe, Mascia, Valeria, Milhau, Julien, Onidi, Loredana, Paparin, Jean-Laurent, Rahali, Rachid, Sais, Efisio, Seifer, Maria, Surleraux, Dominique, Standring, David, Dousson, Cyril
Published in Bioorganic & medicinal chemistry letters (15.09.2016)
Published in Bioorganic & medicinal chemistry letters (15.09.2016)
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Synthesis and antiviral evaluation of a novel series of homoserine-based inhibitors of the hepatitis C virus NS3/4A serine protease
Alexandre, François-René, Brandt, Guillaume, Caillet, Catherine, Chaves, Dominique, Convard, Thierry, Derock, Michel, Gloux, Damien, Griffon, Yann, Lallos, Lisa, Leroy, Frédéric, Liuzzi, Michel, Loi, Anna-Giulia, Moulat, Laure, Musiu, Chiara, Parsy, Christophe, Rahali, Houcine, Roques, Virginie, Seifer, Maria, Standring, David, Surleraux, Dominique
Published in Bioorganic & medicinal chemistry letters (15.09.2015)
Published in Bioorganic & medicinal chemistry letters (15.09.2015)
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In Vitro Antiplasmodial Activities and Synergistic Combinations of Differential Solvent Extracts of the Polyherbal Product, Nefang
Franzoi, Kathrin Diehl, Arrey Tarkang, Protus, Lee, Sukjun, Lee, Eunyoung, Vivarelli, Diego, Freitas-Junior, Lucio, Liuzzi, Michel, Nolé, Tsabang, Ayong, Lawrence S., Agbor, Gabriel Agbor, Okalebo, Faith Apoelot, Guantai, Anastasia Nkatha
Published in BioMed research international (01.01.2014)
Published in BioMed research international (01.01.2014)
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Serendipitous discovery of 2-((phenylsulfonyl)methyl)-thieno[3,2-d]pyrimidine derivatives as novel HIV-1 replication inhibitors
Kim, Junwon, Kwon, Jeongjin, Lee, Doohyun, Jo, Suyeon, Park, Dong-Sik, Choi, Jihyun, Park, Eunjung, Hwang, Jong Yeon, Ko, Yoonae, Choi, Inhee, Ju, Moon Kyeong, Ahn, JiYe, Kim, Junghwan, Han, Sung-Jun, Kim, Tae-Hee, Cechetto, Jonathan, Nam, Jiyoun, Ahn, Sujin, Sommer, Peter, Liuzzi, Michel, Lee, Jinhwa
Published in Bioorganic & medicinal chemistry letters (01.12.2014)
Published in Bioorganic & medicinal chemistry letters (01.12.2014)
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Synthesis and biological evaluation of triazolothienopyrimidine derivatives as novel HIV-1 replication inhibitors
Kim, Junwon, Kwon, Jeongjin, Lee, Doohyun, Jo, Suyeon, Park, Dong-Sik, Choi, Jihyun, Park, Eunjung, Hwang, Jong Yeon, Ko, Yoonae, Choi, Inhee, Ju, Moon Kyeong, Ahn, JiYe, Kim, Junghwan, Han, Sung-Jun, Kim, Tae-Hee, Cechetto, Jonathan, Nam, Jiyoun, Ahn, Sujin, Sommer, Peter, Liuzzi, Michel, No, Zaesung, Lee, Jinhwa
Published in Bioorganic & medicinal chemistry letters (01.01.2013)
Published in Bioorganic & medicinal chemistry letters (01.01.2013)
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Design, synthesis and antiviral evaluation of 2'-C-methyl branched guanosine pronucleotides: the discovery of IDX184, a potent liver-targeted HCV polymerase inhibitor
Sizun, Gwenaëlle, Pierra, Claire, Peyronnet, Jérôme, Badaroux, Eric, Rabeson, Céline, Benzaria-Prad, Samira, Surleraux, Dominique, Loi, Anna Giulia, Musiu, Chiara, Liuzzi, Michel, Seifer, Maria, Standring, David, Sommadossi, Jean-Pierre, Gosselin, Gilles
Published in Future medicinal chemistry (01.09.2015)
Published in Future medicinal chemistry (01.09.2015)
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