The histone methyltransferase inhibitor, DZNep, up-regulates TXNIP, increases ROS production, and targets leukemia cells in AML
Zhou, Jianbiao, Bi, Chonglei, Cheong, Lip-Lee, Mahara, Sylvia, Liu, Shaw-Cheng, Tay, Kian-Ghee, Koh, Tze-Loong, Yu, Qiang, Chng, Wee-Joo
Published in Blood (08.09.2011)
Published in Blood (08.09.2011)
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Journal Article
LIN28B Activation by PRL-3 Promotes Leukemogenesis and a Stem Cell-like Transcriptional Program in AML
Zhou, Jianbiao, Chan, Zit-Liang, Bi, Chonglei, Lu, Xiao, Chong, Phyllis S Y, Chooi, Jing-Yuan, Cheong, Lip-Lee, Liu, Shaw-Cheng, Ching, Ying Qing, Zhou, Yafeng, Osato, Motomi, Tan, Tuan Zea, Ng, Chin Hin, Ng, Siok-Bian, Wang, Shi, Zeng, Qi, Chng, Wee-Joo
Published in Molecular cancer research (01.03.2017)
Published in Molecular cancer research (01.03.2017)
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Journal Article
PRL-3, a metastasis associated tyrosine phosphatase, is involved in FLT3-ITD signaling and implicated in anti-AML therapy
Zhou, Jianbiao, Bi, Chonglei, Chng, Wee-Joo, Cheong, Lip-Lee, Liu, Shaw-Cheng, Mahara, Sylvia, Tay, Kian-Ghee, Zeng, Qi, Li, Jie, Guo, Ke, Tan, Cheng Peow Bobby, Yu, Hanry, Albert, Daniel H, Chen, Chien-Shing
Published in PloS one (12.05.2011)
Published in PloS one (12.05.2011)
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Journal Article
LEO1 Is Regulated by PRL-3 and Mediates Its Oncogenic Properties in Acute Myelogenous Leukemia
CHONG, Phyllis S. Y, JIANBIAO ZHOU, CHEONG, Lip-Lee, LIU, Shaw-Cheng, JINGRU QIAN, TIANNAN GUO, SIU KWAN SZE, QI ZENG, WEE JOO CHNG
Published in Cancer research (Chicago, Ill.) (01.06.2014)
Published in Cancer research (Chicago, Ill.) (01.06.2014)
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Journal Article
The pro-metastasis tyrosine phosphatase, PRL-3 (PTP4A3), is a novel mediator of oncogenic function of BCR-ABL in human chronic myeloid leukemia
Zhou, Jianbiao, Cheong, Lip-Lee, Liu, Shaw-Cheng, Chong, Phyllis S Y, Mahara, Sylvia, Bi, Chonglei, Ong, Kelly Ok, Zeng, Qi, Chng, Wee Joo
Published in Molecular cancer (21.09.2012)
Published in Molecular cancer (21.09.2012)
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Journal Article
Phosphatase of regenerating liver-3 is regulated by signal transducer and activator of transcription 3 in acute myeloid leukemia
Zhou, Jianbiao, Chong, Phyllis SY, Lu, Xiao, Cheong, Lip-Lee, Bi, Chonglei, Liu, Shaw-Cheng, Zhou, Yafeng, Tan, Tuan Zea, Yang, Henry, Chung, Tae-Hoon, Zeng, Qi, Chng, Wee-Joo
Published in Experimental hematology (01.12.2014)
Published in Experimental hematology (01.12.2014)
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Journal Article
EZH2 overexpression in natural killer/T-cell lymphoma confers growth advantage independently of histone methyltransferase activity
Yan, Junli, Ng, Siok-Bian, Tay, Jim Liang-Seah, Lin, Baohong, Koh, Tze Loong, Tan, Joy, Selvarajan, Viknesvaran, Liu, Shaw-Cheng, Bi, Chonglei, Wang, Shi, Choo, Shoa-Nian, Shimizu, Norio, Huang, Gaofeng, Yu, Qiang, Chng, Wee-Joo
Published in Blood (30.05.2013)
Published in Blood (30.05.2013)
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Journal Article
Enhanced activation of STAT pathways and overexpression of survivin confer resistance to FLT3 inhibitors and could be therapeutic targets in AML
Zhou, Jianbiao, Bi, Chonglei, Janakakumara, Jasinghe V., Liu, Shaw-Cheng, Chng, Wee-Joo, Tay, Kian-Ghee, Poon, Lai-Fong, Xie, Zhigang, Palaniyandi, Senthilnathan, Yu, Hanry, Glaser, Keith B., Albert, Daniel H., Davidsen, Steven K., Chen, Chien-Shing
Published in Blood (23.04.2009)
Published in Blood (23.04.2009)
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Journal Article
ITIH3 Is a Potential Biomarker for Early Detection of Gastric Cancer
Chong, Poh Kuan, Lee, Huiyin, Zhou, Jianbiao, Liu, Shaw-Cheng, Loh, Marie Chiew Shia, Wang, Ting Ting, Chan, Siew Pang, Smoot, Duane T, Ashktorab, Hassan, So, Jimmy Bok Yan, Lim, Khong Hee, Yeoh, Khay Guan, Lim, Yoon Pin
Published in Journal of proteome research (02.07.2010)
Published in Journal of proteome research (02.07.2010)
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Journal Article
Determinants of sensitivity to DZNep induced apoptosis in multiple myeloma cells
Xie, Zhigang, Bi, Chonglei, Cheong, Lip Lee, Liu, Shaw Cheng, Huang, Gaofeng, Zhou, Jianbiao, Yu, Qiang, Chen, Chien-Shing, Chng, Wee Joo
Published in PloS one (24.06.2011)
Published in PloS one (24.06.2011)
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Journal Article
Reduced plasma APOA1 level is associated with Gastric Tumor Growth in MKN45 mouse xenograft model
Chong, Poh-Kuan, Lee, Huiyin, Zhou, Jianbiao, Liu, Shaw-Cheng, Loh, Marie Chiew Shia, So, Jimmy Bok Yan, Lim, Khong Hee, Yeoh, Khay-Guan, Lim, Yoon-Pin
Published in Journal of proteomics (16.06.2010)
Published in Journal of proteomics (16.06.2010)
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Journal Article
Clonogenic multiple myeloma cells have shared stemness signature associated with patient survival
Reghunathan, Renji, Bi, Chonglei, Liu, Shaw Cheng, Loong, Koh Tze, Chung, Tae-Hoon, Huang, Gaofeng, Chng, Wee Joo
Published in Oncotarget (01.08.2013)
Published in Oncotarget (01.08.2013)
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Journal Article
Plasma Membrane Proteomics Identifies Biomarkers Associated with T(4;14) Multiple Myeloma
Xie, Zhigang, Gunaratne, Jayantha, Cheong, Lip Lee, Liu, Shaw Cheng, Koh, Tze Loong, Huang, Gaofeng, Blackstock, Walter, Chng, Wee-Joo
Published in Blood (16.11.2012)
Published in Blood (16.11.2012)
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Journal Article
EZH2 Is Aberrantly Expressed and Plays a Pro-Proliferative Role Independent of Its Methyltransferase Activity in Natural Killer/T-Cell Lymphoma
Chng, Wee-Joo, Yan, Junli, NG, Siok-Bian, Tay, Jim, Lin, Baohong, Koh, Tze-Loong, Tan, Joy, Selvarajan, Viknesvaran, Liu, Shaw-Cheng, Bi, Chonglei, Huang, Gaofeng, Yu, Qiang
Published in Blood (16.11.2012)
Published in Blood (16.11.2012)
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Journal Article
The Pro-Metastasis Tyrosine Phosphatase, PRL-3 (PTP4A3), Is a Novel Target of BCR-ABL Signaling Involved in Human Chronic Myeloid Leukemia
Zhou, Jianbiao, Cheong, Lip-Lee, Mahara, Sylvia, Liu, Shaw-Cheng, Chong, Phyllis SY, Bi, Chonglei, Koh, Tze-Loong, Ong, Kelly OK, Zeng, Qi, Chng, Wee-Joo
Published in Blood (18.11.2011)
Published in Blood (18.11.2011)
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Journal Article
The Histone Methyltransferase Inhibitor, DZNep, Upregulates TXNIP, Increases ROS Production and Targets Leukemia Cells In AML
Zhou, Jianbiao, Bi, Chonglei, Liu, Shaw-Cheng, Tay, Kian-Ghee, Cheong, Lip-Lee, Koh, Tze-Loong, Yu, Qiang, Chng, Wee-Joo
Published in Blood (19.11.2010)
Published in Blood (19.11.2010)
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Journal Article
Identification of Core Gene Signature Associated with Synergism Between ABT-869, a FLT3 Inhibitor and SAHA, a HDAC Inhibitor in AML with FLT3-ITD Mutation
Zhou, Jianbiao, Bi, Chonglei, Liu, Shaw-Cheng, Chng, Wee-Joo, Tay, Kian-Ghee, Yu, Hanry, Glaser, Keith, Albert, Daniel, Davidsen, Steven K, Chen, Chien-Shing
Published in Blood (16.11.2008)
Published in Blood (16.11.2008)
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Journal Article
Structural basis for termination of AIM2-mediated signaling by p202
Ru, Heng, Ni, Xiangmin, Zhao, Lixia, Crowley, Christopher, Ding, Wei, Hung, Li-Wei, Shaw, Neil, Cheng, Genhong, Liu, Zhi-Jie
Published in Cell research (01.06.2013)
Published in Cell research (01.06.2013)
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