Pharmacologic Characterization of the Cloned Human Trace Amine-Associated Receptor1 (TAAR1) and Evidence for Species Differences with the Rat TAAR1
Wainscott, David B, Little, Sheila P, Yin, Tinggui, Tu, Yuan, Rocco, Vincent P, He, John X, Nelson, David L
Published in The Journal of pharmacology and experimental therapeutics (01.01.2007)
Published in The Journal of pharmacology and experimental therapeutics (01.01.2007)
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Characterization of the enzymatic activity of human kallikrein 6: autoactivation, substrate specificity, and regulation by inhibitors
Magklara, Angeliki, Mellati, Ali A, Wasney, Gregory A, Little, Sheila P, Sotiropoulou, Georgia, Becker, Gerald W, Diamandis, Eleftherios P
Published in Biochemical and biophysical research communications (08.08.2003)
Published in Biochemical and biophysical research communications (08.08.2003)
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Intracellular Binding Site for a Positive Allosteric Modulator of the Dopamine D1 Receptor
Wang, Xushan, Heinz, Beverly A, Qian, Yue-Wei, Carter, Joan H, Gadski, Robert A, Beavers, Lisa S, Little, Sheila P, Yang, Charles R, Beck, James P, Hao, Junliang, Schaus, John M, Svensson, Kjell A, Bruns, Robert F
Published in Molecular pharmacology (01.10.2018)
Published in Molecular pharmacology (01.10.2018)
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Molecular cloning and pharmacological characterization of the guinea pig 5-HT1E receptor
FENGJU BAI, TINGGUI YIN, JOHNSTONE, Edward M, CHEN SU, VARGA, Gabor, LITTLE, Sheila P, NELSON, David L
Published in European journal of pharmacology (26.01.2004)
Published in European journal of pharmacology (26.01.2004)
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Journal Article
Reactive glia express cytosolic phospholipase A2 after transient global forebrain ischemia in the rat
Clemens, J A, Stephenson, D T, Smalstig, E B, Roberts, E F, Johnstone, E M, Sharp, J D, Little, S P, Kramer, R M
Published in Stroke (1970) (01.03.1996)
Published in Stroke (1970) (01.03.1996)
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Journal Article
Lack of apolipoprotein E dramatically reduces amyloid β-peptide deposition
Bales, Kelly R, Verina, Tatyana, Dodel, Richard C, Du, Yansheng, Altstiel, Larry, Bender, Mark, Hyslop, Paul, Johnstone, Edward M, Little, Sheila P, Cummins, David J, Piccardo, Pedro, Ghetti, Bernardino, Paul, Steven M
Published in Nature genetics (01.11.1997)
Published in Nature genetics (01.11.1997)
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Development of an Immunofluorometric Assay and Quantification of Human Kallikrein 7 in Tissue Extracts and Biological Fluids
Kishi, Tadaaki, Soosaipillai, Antoninus, Grass, Linda, Little, Sheila P, Johnstone, Edward M, Diamandis, Eleftherios P
Published in Clinical chemistry (Baltimore, Md.) (01.04.2004)
Published in Clinical chemistry (Baltimore, Md.) (01.04.2004)
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Synthesis and structure-activity relationships of benzophenones as inhibitors of cathepsin D
Whitesitt, Celia A., Simon, Richard L., Reel, Jon K., Sigmund, Sandra K., Phillips, Michael L., Kevin Shadle, J., Heinz, Lawrence J., Koppel, Gary A., Hunden, David C., Lifer, Sherryl L., Berry, Dennis, Ray, Judy, Little, Sheila P, Xiadong Liu, Marshall, Winston S., Panetta, Jill A.
Published in Bioorganic & medicinal chemistry letters (17.09.1996)
Published in Bioorganic & medicinal chemistry letters (17.09.1996)
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Journal Article
The Spectrum of Human Kallikrein 6 (Zyme/Protease M/Neurosin) Expression in Human Tissues as Assessed by Immunohistochemistry
Petraki, Constantina D, Karavana, Vassiliki N, Skoufogiannis, Pavlos T, Little, Sheila P, Howarth, David J.C, Yousef, George M, Diamandis, Eleftherios P
Published in The journal of histochemistry and cytochemistry (01.11.2001)
Published in The journal of histochemistry and cytochemistry (01.11.2001)
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Biochemical and kinetic characterization of BACE1: investigation into the putative species‐specificity for β‐ and β′‐cleavage sites by human and murine BACE1
Yang, Hsiu‐Chiung, Chai, Xiyun, Mosior, Marian, Kohn, Wayne, Boggs, Leonard N., Erickson, Jon A., McClure, Don B., Yeh, Wu‐Kuang, Zhang, Lianshen, Gonzalez‐DeWhitt, Patricia, Mayer, John P., Martin, Jose Alfredo, Hu, Jingdan, Chen, Shu‐hui, Bueno, Ana Belen, Little, Sheila P., McCarthy, James R., May, Patrick C.
Published in Journal of neurochemistry (01.12.2004)
Published in Journal of neurochemistry (01.12.2004)
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Journal Article
Expression of potentially amyloidogenic derivatives of the Alzheimer amyloid precursor protein in cultured 293 cells
Johnstone, Edward M, Oltersdorf, Tilman, Bales, Kelly R, Chaney, Michael O, Santerre, Robert F, Little, Sheila P
Published in Neuroscience letters (24.10.1994)
Published in Neuroscience letters (24.10.1994)
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P4-339 Stereoselective inhibition of amyloid beta peptide secretion by LY450139, a novel functional gamma secretase inhibitor
Gitter, Bruce D., Czilli, Dan L., Li, Weiying, Dieckman, Donna K., Bender, Mark H., Nissen, Jeffrey S., Mabry, Thomas E., Yin, Tinggui, Boggs, Leonard N., McClure, Don B., Little, Sheila P., Johnstone, Edward M., Audia, James E., May, Patrick C., Hyslop, Paul A.
Published in Neurobiology of aging (01.07.2004)
Published in Neurobiology of aging (01.07.2004)
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Prostate-specific antigen (PSA)-mediated proliferation, androgenic regulation and inhibitory effects of LY312340 in HOS-TE85 (TE85) human osteosarcoma cells
Gygi, Christian M, Leibovitch, Ilan Y, Adlington, Robert, Baldwin, Jack E, Chen, Beining, Mccoull, William, Pritchard, Gareth J, Becker, Gerald W, Dixon, Eric P, Little, Sheila P, Sutkowski, Debra M, Teater, Carroll, Neubauer, Blake Lee
Published in Anticancer research (01.09.2002)
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Published in Anticancer research (01.09.2002)
Journal Article
Rat B2 Sequences Are Induced in the Hippocampal CA1 Region After Transient Global Cerebral Ischemia
Liu, Xiaodong, Clemens, James A., Yin, Tinggui, Stephenson, Diane T., Johnstone, Edward M., Du, Yansheng, Panetta, Jill A., Paul, Steven M., Little, Sheila P.
Published in The Journal of biological chemistry (01.10.1999)
Published in The Journal of biological chemistry (01.10.1999)
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Journal Article
Global ischemia activates nuclear factor-kappa B in forebrain neurons of rats
Clemens, J A, Stephenson, D T, Smalstig, E B, Dixon, E P, Little, S P
Published in Stroke (1970) (01.05.1997)
Published in Stroke (1970) (01.05.1997)
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Functional properties of carbohydrate-depleted tissue plasminogen activator
Little, Sheila P, Bang, Nils U, Harms, Cathy S, Marks, Carole A, Mattler, Lawrence E
Published in Biochemistry (Easton) (01.12.1984)
Published in Biochemistry (Easton) (01.12.1984)
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Journal Article
Drug-Induced Neuroprotection From Global Ischemia Is Associated With Prevention of Persistent but Not Transient Activation of Nuclear Factor-κB in Rats
Clemens, James A., Stephenson, Diane T., Yin, Tinggui, Smalstig, E. Barry, Panetta, Jill A., Little, Sheila P.
Published in Stroke (1970) (01.03.1998)
Published in Stroke (1970) (01.03.1998)
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