Cancer metabolism: a therapeutic perspective
Martinez-Outschoorn, Ubaldo E., Peiris-Pagés, Maria, Pestell, Richard G., Sotgia, Federica, Lisanti, Michael P.
Published in Nature reviews. Clinical oncology (01.01.2017)
Published in Nature reviews. Clinical oncology (01.01.2017)
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Journal Article
Mitochondria as new therapeutic targets for eradicating cancer stem cells: Quantitative proteomics and functional validation via MCT1/2 inhibition
Lamb, Rebecca, Harrison, Hannah, Hulit, James, Smith, Duncan L, Lisanti, Michael P, Sotgia, Federica
Published in Oncotarget (30.11.2014)
Published in Oncotarget (30.11.2014)
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Journal Article
Power Surge: Supporting Cells “Fuel” Cancer Cell Mitochondria
Martinez-Outschoorn, Ubaldo E., Sotgia, Federica, Lisanti, Michael P.
Published in Cell metabolism (04.01.2012)
Published in Cell metabolism (04.01.2012)
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Journal Article
Repurposing atovaquone: targeting mitochondrial complex III and OXPHOS to eradicate cancer stem cells
Fiorillo, Marco, Lamb, Rebecca, Tanowitz, Herbert B, Mutti, Luciano, Krstic-Demonacos, Marija, Cappello, Anna Rita, Martinez-Outschoorn, Ubaldo E, Sotgia, Federica, Lisanti, Michael P
Published in Oncotarget (07.06.2016)
Published in Oncotarget (07.06.2016)
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Journal Article
Oncogenes induce the cancer-associated fibroblast phenotype: Metabolic symbiosis and "fibroblast addiction" are new therapeutic targets for drug discovery
Lisanti, Michael P., Martinez-Outschoorn, Ubaldo E., Sotgia, Federica
Published in Cell cycle (Georgetown, Tex.) (01.09.2013)
Published in Cell cycle (Georgetown, Tex.) (01.09.2013)
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Journal Article
Metabolic reprogramming of cancer-associated fibroblasts by TGF-β drives tumor growth: Connecting TGF-β signaling with "Warburg-like" cancer metabolism and L-lactate production
Guido, Carmela, Whitaker-Menezes, Diana, Capparelli, Claudia, Balliet, Renee, Lin, Zhao, Pestell, Richard G., Howell, Anthony, Aquila, Saveria, Andò, Sebastiano, Martinez-Outschoorn, Ubaldo, Sotgia, Federica, Lisanti, Michael P.
Published in Cell cycle (Georgetown, Tex.) (15.08.2012)
Published in Cell cycle (Georgetown, Tex.) (15.08.2012)
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Journal Article
Ketone body utilization drives tumor growth and metastasis
Martinez-Outschoorn, Ubaldo E., Lin, Zhao, Whitaker-Menezes, Diana, Howell, Anthony, Sotgia, Federica, Lisanti, Michael P.
Published in Cell cycle (Georgetown, Tex.) (01.11.2012)
Published in Cell cycle (Georgetown, Tex.) (01.11.2012)
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Journal Article
Mitochondrial biogenesis is required for the anchorage-independent survival and propagation of stem-like cancer cells
De Luca, Arianna, Fiorillo, Marco, Peiris-Pagès, Maria, Ozsvari, Bela, Smith, Duncan L, Sanchez-Alvarez, Rosa, Martinez-Outschoorn, Ubaldo E, Cappello, Anna Rita, Pezzi, Vincenzo, Lisanti, Michael P, Sotgia, Federica
Published in Oncotarget (20.06.2015)
Published in Oncotarget (20.06.2015)
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Journal Article
Ketones and lactate "fuel" tumor growth and metastasis: Evidence that epithelial cancer cells use oxidative mitochondrial metabolism
Bonuccelli, Gloria, Tsirigos, Aristotelis, Whitaker-Menezes, Diana, Pavlides, Stephanos, Pestell, Richard G., Chiavarina, Barbara, Frank, Philippe G., Flomenberg, Neal, Howell, Anthony, Martinez-Outschoorn, Ubaldo E., Sotgia, Federica, Lisanti, Michael P.
Published in Cell cycle (Georgetown, Tex.) (01.09.2010)
Published in Cell cycle (Georgetown, Tex.) (01.09.2010)
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Journal Article
The reverse Warburg effect: Aerobic glycolysis in cancer associated fibroblasts and the tumor stroma
Pavlides, Stephanos, Whitaker-Menezes, Diana, Castello-Cros, Remedios, Flomenberg, Neal, Witkiewicz, Agnieszka K., Frank, Philippe G., Casimiro, Mathew C., Wang, Chenguang, Fortina, Paolo, Addya, Sankar, Pestell, Richard G., Martinez-Outschoorn, Ubaldo E., Sotgia, Federica, Lisanti, Michael P.
Published in Cell cycle (Georgetown, Tex.) (01.12.2009)
Published in Cell cycle (Georgetown, Tex.) (01.12.2009)
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Journal Article
GPER mediates the angiocrine actions induced by IGF1 through the HIF-1α/VEGF pathway in the breast tumor microenvironment
De Francesco, Ernestina M, Sims, Andrew H, Maggiolini, Marcello, Sotgia, Federica, Lisanti, Michael P, Clarke, Robert B
Published in Breast cancer research : BCR (06.12.2017)
Published in Breast cancer research : BCR (06.12.2017)
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Journal Article
Role of Cholesterol in the Development and Progression of Breast Cancer
Llaverias, Gemma, Danilo, Christiane, Mercier, Isabelle, Daumer, Kristin, Capozza, Franco, Williams, Terence M, Sotgia, Federica, Lisanti, Michael P, Frank, Philippe G
Published in The American journal of pathology (2011)
Published in The American journal of pathology (2011)
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Journal Article
Vitamin C and Doxycycline: A synthetic lethal combination therapy targeting metabolic flexibility in cancer stem cells (CSCs)
De Francesco, Ernestina Marianna, Bonuccelli, Gloria, Maggiolini, Marcello, Sotgia, Federica, Lisanti, Michael P
Published in Oncotarget (15.09.2017)
Published in Oncotarget (15.09.2017)
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Journal Article