Engineered Antibody Fc Variants with Enhanced Effector Function
Lazar, Greg A., Dang, Wei, Karki, Sher, Vafa, Omid, Peng, Judy S., Hyun, Linus, Chan, Cheryl, Chung, Helen S., Eivazi, Araz, Yoder, Sean C., Vielmetter, Jost, Carmichael, David F., Hayes, Robert J., Dahiyat, Bassil I.
Published in Proceedings of the National Academy of Sciences - PNAS (14.03.2006)
Published in Proceedings of the National Academy of Sciences - PNAS (14.03.2006)
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Journal Article
Selection of high-affinity Centyrin FN3 domains from a simple library diversified at a combination of strand and loop positions
Diem, Michael D., Hyun, Linus, Yi, Fang, Hippensteel, Randi, Kuhar, Elise, Lowenstein, Cassandra, Swift, Edward J., O'Neil, Karyn T., Jacobs, Steven A.
Published in Protein engineering, design and selection (01.10.2014)
Published in Protein engineering, design and selection (01.10.2014)
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Journal Article
Mechanisms of self-association of a human monoclonal antibody CNTO607
Bethea, Deidra, Wu, Sheng-Jiun, Luo, Jinquan, Hyun, Linus, Lacy, Eilyn R., Teplyakov, Alexey, Jacobs, Steven A., O'Neil, Karyn T., Gilliland, Gary L., Feng, Yiqing
Published in Protein engineering, design and selection (01.10.2012)
Published in Protein engineering, design and selection (01.10.2012)
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Journal Article
PROSTATE SPECIFIC MEMBRANE ANTIGEN BINDING FIBRONECTIN TYPE III DOMAINS
TRACY SPINKA-DOMS, LINUS HYUN, ROSA CARDOSO, MICHAEL DIEM, SHALOM GOLDBERG, DONNA KLEIN, KARYN O'NEIL, STEVEN JACOBS
Year of Publication 11.01.2022
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Year of Publication 11.01.2022
Patent
Inactivation of TNF Signaling by Rationally Designed Dominant-Negative TNF Variants
Steed, Paul M., Tansey, Malú G., Zalevsky, Jonathan, Zhukovsky, Eugene A., Desjarlais, John R., Szymkowski, David E., Abbott, Christina, Carmichael, David, Chan, Cheryl, Cherry, Lisa, Cheung, Peter, Chirino, Arthur J., Chung, Hyo H., Doberstein, Stephen K., Eivazi, Araz, Filikov, Anton V., Gao, Sarah X., Hubert, René S., Hwang, Marian, Hyun, Linus, Kashi, Sandhya, Kim, Alice, Kim, Esther, Kung, James, Martinez, Sabrina P., Muchhal, Umesh S., Nguyen, Duc-Hanh T., O'Brien, Christopher, O'Keefe, Donald, Singer, Karen, Vafa, Omid, Vielmetter, Jost, Yoder, Sean C., Dahiyat, Bassil I.
Published in Science (American Association for the Advancement of Science) (26.09.2003)
Published in Science (American Association for the Advancement of Science) (26.09.2003)
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Journal Article
EGFR AND C-MET-FIBRONECTIN TYPE III DOMAIN BINDING MOLECULES
ALASTAIR KING, LINUS HYUN, MICHAEL DIEM, DONNA KLEIN, KARYN O'NEIL, MARK ANDERSON, KRISTEN PICHA, SHERI MOORES, RICARDO ATTAR, STEVEN JACOBS
Year of Publication 07.03.2019
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Year of Publication 07.03.2019
Patent
Abstract LB-312: Bispecific Centyrin simultaneously targeting EGFR and c-Met demonstrates improved activity compared to the mixture of single agents
Klein, Donna, Jacobs, Steve, Sheri, Moores, Anderson, Mark, Attar, Ricardo, Barnakov, Alexander, Brosnan, Kerry, Bushey, Barbara, Chevalier, Kristen, Chin, Diana, Cornejo, Carla, Diem, Mike, Hyun, Linus, Kuhar, Elise, McCabe, Francis, Picha, Kristen, Spinka-Doms, Tracy, Swift, Edward, O'Neil, Karyn
Published in Cancer research (Chicago, Ill.) (15.04.2013)
Published in Cancer research (Chicago, Ill.) (15.04.2013)
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Journal Article
MOLECULES WITH ENGINEERED ANTIBODY CONSTANT REGION VARIANTS
CHI, Ellen, SINGH, Sanjaya, HYUN, Linus, FURMAN, Jennifer, LACOMBE, Ann, CASE, Martin, ZHOU, Hong Mimi
Year of Publication 04.07.2024
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Year of Publication 04.07.2024
Patent
MOLECULES WITH ENGINEERED ANTIBODY CONSTANT REGION VARIANTS
CHI, Ellen, SINGH, Sanjaya, HYUN, Linus, ZHOU, Hong, Mimi, FURMAN, Jennifer, LACOMBE, Ann, CASE, Martin
Year of Publication 28.02.2024
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Year of Publication 28.02.2024
Patent
MOLECULES WITH ENGINEERED ANTIBODY CONSTANT REGION VARIANTS
CHI, Ellen, SINGH, Sanjaya, HYUN, Linus, ZHOU, Hong, FURMAN, Jennifer, LACOMBE, Ann, CASE, Martin
Year of Publication 07.12.2023
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Year of Publication 07.12.2023
Patent
Molecules with engineered antibody constant region variants
SINGH Sanjaya, ZHOU Hong Mimi, LACOMBE Ann, CASE Martin, HYUN Linus, FURMAN Jennifer, CHI Ellen
Year of Publication 01.12.2023
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Year of Publication 01.12.2023
Patent
Prostate specific membrane antigen binding fibronectin type iii domains
Cardoso, Rosa, Spinka-Doms, Tracy, Jacobs, Steven, Klein, Donna, Diem, Michael, Goldberg, Shalom, Hyun, Linus, O'Neil, Karyn
Year of Publication 06.08.2024
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Year of Publication 06.08.2024
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MOLECULES WITH ENGINEERED ANTIBODY CONSTANT REGION VARIANTS
CASE, MARTIN, FURMAN, JENNIFER, SINGH, SANJAYA, CHI, ELLEN, ZHOU, HONG MIMI, HYUN, LINUS, LACOMBE, ANN
Year of Publication 27.10.2022
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Year of Publication 27.10.2022
Patent
MOLECULES WITH ENGINEERED ANTIBODY CONSTANT REGION VARIANTS
CHI, Ellen, SINGH, Sanjaya, HYUN, Linus, ZHOU, Hong, FURMAN, Jennifer, LACOMBE, Ann, CASE, Martin
Year of Publication 27.10.2022
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Year of Publication 27.10.2022
Patent
EGFR AND C-MET-FIBRONECTIN TYPE III DOMAIN BINDING MOLECULES
HYUN, Linus, MOORES, Sheri, ANDERSON, Mark, O'NEIL, Karyn, ATTAR, Ricardo, JACOBS, Steven, PICHA, Kristen, DIEM, Michael, KING, Alastair, KLEIN, Donna
Year of Publication 06.07.2022
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Year of Publication 06.07.2022
Patent
Prostate specific membrane antigen binding fibronectin type III domains
CARDOSO, Rosa, HYUN, Linus, GOLDBERG, Shalom, O'NEIL, Karyn, JACOBS, Steven, SPINKA-DOMS, Tracy, DIEM, Michael, KLEIN, Donna
Year of Publication 12.05.2022
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Year of Publication 12.05.2022
Patent
EGFR and c-Met-fibronectin type III domain binding molecules
Jacobs, Steven, Klein, Donna, Diem, Michael, Anderson, Mark, Picha, Kristen, Attar, Ricardo, Moores, Sheri, King, Alastair, Hyun, Linus, O'Neil, Karyn
Year of Publication 31.03.2022
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Year of Publication 31.03.2022
Patent