The acute nociceptive signals induced by bradykinin in rat sensory neurons are mediated by inhibition of M-type K+ channels and activation of Ca2+-activated Cl- channels
Liu, Boyi, Linley, John E, Du, Xiaona, Zhang, Xuan, Ooi, Lezanne, Zhang, Hailin, Gamper, Nikita
Published in The Journal of clinical investigation (01.04.2010)
Published in The Journal of clinical investigation (01.04.2010)
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Journal Article
Intertidal boulder transport: A proposed methodology adopting Radio Frequency Identification (RFID) technology to quantify storm induced boulder mobility
Hastewell, Linley John, Schaefer, Martin, Bray, Malcolm, Inkpen, Robert
Published in Earth surface processes and landforms (15.03.2019)
Published in Earth surface processes and landforms (15.03.2019)
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Journal Article
Recombinant expression and in vitro characterisation of active Huwentoxin-IV
Sermadiras, Isabelle, Revell, Jefferson, Linley, John E, Sandercock, Alan, Ravn, Peter
Published in PloS one (06.12.2013)
Published in PloS one (06.12.2013)
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Journal Article
Neurological perspectives on voltage-gated sodium channels
EIJKELKAMP, Niels, LINLEY, John E, BAKER, Mark D, MINETT, Michael S, CREGG, Roman, WERDEHAUSEN, Robert, RUGIERO, François, WOOD, John N
Published in Brain (London, England : 1878) (01.09.2012)
Published in Brain (London, England : 1878) (01.09.2012)
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Journal Article
Mapping protein interactions of sodium channel NaV1.7 using epitope‐tagged gene‐targeted mice
Kanellopoulos, Alexandros H, Koenig, Jennifer, Huang, Honglei, Pyrski, Martina, Millet, Queensta, Lolignier, Stéphane, Morohashi, Toru, Gossage, Samuel J, Jay, Maude, Linley, John E, Baskozos, Georgios, Kessler, Benedikt M, Cox, James J, Dolphin, Annette C, Zufall, Frank, Wood, John N, Zhao, Jing
Published in The EMBO journal (01.02.2018)
Published in The EMBO journal (01.02.2018)
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Journal Article
Reactive oxygen species are second messengers of neurokinin signaling in peripheral sensory neurons
Linley, John E., Ooi, Lezanne, Pettinger, Louisa, Kirton, Hannah, Boyle, John P., Peers, Chris, Gamper, Nikita
Published in Proceedings of the National Academy of Sciences - PNAS (12.06.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (12.06.2012)
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Journal Article
Antibodies binding the head domain of P2X4 inhibit channel function and reverse neuropathic pain
Williams, Wendy A, Linley, John E, Jones, Clare A, Shibata, Yoko, Snijder, Arjan, Button, James, Hatcher, Jon P, Huang, Ling, Taddese, Bruck, Thornton, Peter, Schofield, Darren J, Thom, George, Popovic, Bojana, Dosanjh, Bhupinder, Wilkinson, Trevor, Hughes, Jane, Dobson, Claire L, Groves, Maria A, Webster, Carl I, Billinton, Andy, Vaughan, Tristan J, Chessell, Iain
Published in Pain (Amsterdam) (01.09.2019)
Published in Pain (Amsterdam) (01.09.2019)
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Journal Article
Potency optimization of Huwentoxin-IV on hNav1.7: A neurotoxin TTX-S sodium-channel antagonist from the venom of the Chinese bird-eating spider Selenocosmia huwena
Revell, Jefferson D., Lund, Per-Eric, Linley, John E., Metcalfe, Jacky, Burmeister, Nicole, Sridharan, Sudharsan, Jones, Clare, Jermutus, Lutz, Bednarek, Maria A.
Published in Peptides (New York, N.Y. : 1980) (01.06.2013)
Published in Peptides (New York, N.Y. : 1980) (01.06.2013)
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Journal Article
Bradykinin controls pool size of sensory neurons expressing functional δ-opioid receptors
Pettinger, Louisa, Gigout, Sylvain, Linley, John E, Gamper, Nikita
Published in The Journal of neuroscience (26.06.2013)
Published in The Journal of neuroscience (26.06.2013)
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Journal Article
Regulation of Nav1.7: A Conserved SCN9A Natural Antisense Transcript Expressed in Dorsal Root Ganglia
Koenig, Jennifer, Werdehausen, Robert, Linley, John E, Habib, Abdella M, Vernon, Jeffrey, Lolignier, Stephane, Eijkelkamp, Niels, Zhao, Jing, Okorokov, Andrei L, Woods, C Geoffrey, Wood, John N, Cox, James J
Published in PloS one (02.06.2015)
Published in PloS one (02.06.2015)
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Journal Article
Inhibition of M Current in Sensory Neurons by Exogenous Proteases: A Signaling Pathway Mediating Inflammatory Nociception
Linley, John E, Rose, Kirstin, Patil, Mayur, Robertson, Brian, Akopian, Armen N, Gamper, Nikita
Published in The Journal of neuroscience (29.10.2008)
Published in The Journal of neuroscience (29.10.2008)
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Journal Article
Understanding inflammatory pain: ion channels contributing to acute and chronic nociception
Linley, John E., Rose, Kirstin, Ooi, Lezanne, Gamper, Nikita
Published in Pflügers Archiv (01.04.2010)
Published in Pflügers Archiv (01.04.2010)
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Journal Article
TRPC3 and TRPC6 are essential for normal mechanotransduction in subsets of sensory neurons and cochlear hair cells
Quick, Kathryn, Zhao, Jing, Eijkelkamp, Niels, Linley, John E., Rugiero, Francois, Cox, James J., Raouf, Ramin, Gringhuis, Martine, Sexton, Jane E., Abramowitz, Joel, Taylor, Ruth, Forge, Andy, Ashmore, Jonathan, Kirkwood, Nerissa, Kros, Corné J., Richardson, Guy P., Freichel, Marc, Flockerzi, Veit, Birnbaumer, Lutz, Wood, John N.
Published in Open biology (01.05.2012)
Published in Open biology (01.05.2012)
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Journal Article
M channel enhancers and physiological M channel block
Linley, John E., Pettinger, Louisa, Huang, Dongyang, Gamper, Nikita
Published in The Journal of physiology (01.02.2012)
Published in The Journal of physiology (01.02.2012)
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Journal Article
Potential role of reduced basolateral potassium (IKCa3.1) channel expression in the pathogenesis of diarrhoea in ulcerative colitis
Al-Hazza, Adel, Linley, John E, Aziz, Qadeer, MacLennan, Kenneth A, Hunter, Malcolm, Sandle, Geoffrey I
Published in The Journal of pathology (01.02.2012)
Published in The Journal of pathology (01.02.2012)
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Journal Article