Rapid copper-mediated radiosynthesis optimization for a novel monoacylglycerol lipase PET tracer on a high-throughput microdroplet radiochemistry platform
Lu, Yingqing, He, Yingfang, Schibli, Roger, Mu, Linjing, van Dam, R. Michael
Published in Nuclear medicine and biology (01.11.2023)
Published in Nuclear medicine and biology (01.11.2023)
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Journal Article
The impact of tau deposition and hypometabolism on cognitive impairment and longitudinal cognitive decline
Boccalini, Cecilia, Ribaldi, Federica, Hristovska, Ines, Arnone, Annachiara, Peretti, Débora Elisa, Mu, Linjing, Scheffler, Max, Perani, Daniela, Frisoni, Giovanni B., Garibotto, Valentina
Published in Alzheimer's & dementia (01.01.2024)
Published in Alzheimer's & dementia (01.01.2024)
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Journal Article
Development of radiofluorinated MLN-4760 derivatives for PET imaging of the SARS-CoV-2 entry receptor ACE2
Wang, Jinling, Beyer, Darja, Vaccarin, Christian, He, Yingfang, Tanriver, Matthias, Benoit, Roger, Deupi, Xavier, Mu, Linjing, Bode, Jeffrey W, Schibli, Roger, Müller, Cristina
Published in European journal of nuclear medicine and molecular imaging (27.07.2024)
Published in European journal of nuclear medicine and molecular imaging (27.07.2024)
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Journal Article
Quantitative Evaluation of a Novel PET Radioligand for the Monoacylglycerol Lipase (MAGL) in Non-Human Primates
Gu, Jiwei, Huang, Henry, Carson, Richard, Wenn, Mike, Holden, Daniel, Mu, Linjing, Zhang, Li, Ropchan, Jim, Gao, Hong, He, Yingfang
Published in Nuclear medicine and biology (01.11.2023)
Published in Nuclear medicine and biology (01.11.2023)
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Journal Article
Identification of (R)-[18F]YH134 as a promising reversible MAGL PET tracer and the impact of peripheral MAGL blockade on its brain uptake
Mu, Linjing, He, Yingfang, Krämer, Stefanie, Grether, Uwe, Wittwer, Matthias, Honer, Michael, Keller, Claudia, Schibli, Roger, Gobbi, Luca
Published in Nuclear medicine and biology (01.11.2023)
Published in Nuclear medicine and biology (01.11.2023)
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Journal Article
Structure-Affinity Relationships of 2,3,4,5-Tetrahydro-1 H -3-benzazepine and 6,7,8,9-Tetrahydro-5 H -benzo[7]annulen-7-amine Analogues and the Discovery of a Radiofluorinated 2,3,4,5-Tetrahydro-1 H -3-benzazepine Congener for Imaging GluN2B Subunit-Containing N -Methyl-d-aspartate Receptors
Ahmed, Hazem, Haider, Ahmed, Varisco, Jasmine, Stanković, Maja, Wallimann, Rahel, Gruber, Stefan, Iten, Irina, Häne, Surya, Müller Herde, Adrienne, Keller, Claudia, Schibli, Roger, Schepmann, Dirk, Mu, Linjing, Wünsch, Bernhard, Ametamey, Simon M
Published in Journal of medicinal chemistry (14.11.2019)
Published in Journal of medicinal chemistry (14.11.2019)
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Journal Article
Development of High Brain-Penetrant and Reversible Monoacylglycerol Lipase PET Tracers for Neuroimaging
He, Yingfang, Schild, Matthias, Grether, Uwe, Benz, Jorg, Leibrock, Lea, Heer, Dominik, Topp, Andreas, Collin, Ludovic, Kuhn, Bernd, Wittwer, Matthias, Keller, Claudia, Gobbi, Luca C., Schibli, Roger, Mu, Linjing
Published in Journal of medicinal chemistry (10.02.2022)
Published in Journal of medicinal chemistry (10.02.2022)
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Journal Article
SP-005 - Development of reversible monoacylglycerol lipase PET tracers with improved brain uptake
He, Yingfang, Schild, Matthias, Grether, Uwe, Humm, Roland, Keller, Claudia, Schibli, Roger, Gobbi, Luca, Mu, Linjing
Published in Nuclear medicine and biology (01.05.2021)
Published in Nuclear medicine and biology (01.05.2021)
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Journal Article
Development of reversible monoacylglycerol lipase PET tracers with improved brain uptake
He, Yingfang, Schild, Matthias, Grether, Uwe, Humm, Roland, Keller, Claudia, Schibli, Roger, Gobbi, Luca, Mu, Linjing
Published in Nuclear medicine and biology (01.05.2021)
Published in Nuclear medicine and biology (01.05.2021)
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Journal Article
Identification and Preclinical Development of a 2,5,6-Trisubstituted Fluorinated Pyridine Derivative as a Radioligand for the Positron Emission Tomography Imaging of Cannabinoid Type 2 Receptors
Haider, Ahmed, Gobbi, Luca, Kretz, Julian, Ullmer, Christoph, Brink, Andreas, Honer, Michael, Woltering, Thomas J, Muri, Dieter, Iding, Hans, Bürkler, Markus, Binder, Martin, Bartelmus, Christian, Knuesel, Irene, Pacher, Pal, Herde, Adrienne Müller, Spinelli, Francesco, Ahmed, Hazem, Atz, Kenneth, Keller, Claudia, Weber, Markus, Schibli, Roger, Mu, Linjing, Grether, Uwe, Ametamey, Simon M
Published in Journal of medicinal chemistry (24.09.2020)
Published in Journal of medicinal chemistry (24.09.2020)
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Journal Article
Evaluation of 4-oxo-quinoline-based CB2 PET radioligands in R6/2 chorea huntington mouse model and human ALS spinal cord tissue
Haider, Ahmed, Spinelli, Francesco, Herde, Adrienne Müller, Mu, Boshuai, Keller, Claudia, Margelisch, Markus, Weber, Markus, Schibli, Roger, Mu, Linjing, Ametamey, Simon M.
Published in European journal of medicinal chemistry (10.02.2018)
Published in European journal of medicinal chemistry (10.02.2018)
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Journal Article
In Vitro and In Vivo Evaluation of ABCG2 (BCRP) Inhibitors Derived from Ko143
Zechner, Melanie, Castro Jaramillo, Claudia A., Zubler, Nadine S., Taddio, Marco F., Mu, Linjing, Altmann, Karl-Heinz, Krämer, Stefanie D.
Published in Journal of medicinal chemistry (25.05.2023)
Published in Journal of medicinal chemistry (25.05.2023)
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Journal Article
Identification of ( R )-[ 18 F]YH134 for Monoacylglycerol Lipase Neuroimaging and Exploration of Its Use for Central Nervous System and Peripheral Drug Development
He, Yingfang, Krämer, Stefanie D, Grether, Uwe, Wittwer, Matthias B, Collin, Ludovic, Kuhn, Bernd, Topp, Andreas, Heer, Dominik, O'Hara, Fionn, Honer, Michael, Pavlovic, Anto, Richter, Hans, Ritter, Martin, Rombach, Didier, Keller, Claudia, Gobbi, Luca, Mu, Linjing
Published in Journal of Nuclear Medicine (01.02.2024)
Published in Journal of Nuclear Medicine (01.02.2024)
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Journal Article
On the consensus nomenclature rules for radiopharmaceutical chemistry – Reconsideration of radiochemical conversion
Herth, Matthias M., Ametamey, Simon, Antuganov, Dmitrii, Bauman, Andreas, Berndt, Mathias, Brooks, Allen F., Bormans, Guy, Choe, Yearn Seong, Gillings, Nic, Häfeli, Urs O., James, Michelle L., Kopka, Klaus, Kramer, Vasko, Krasikova, Raisa, Madsen, Jacob, Mu, Linjing, Neumaier, Bernd, Piel, Markus, Rösch, Frank, Ross, Tobias, Schibli, Roger, Scott, Peter J.H., Shalgunov, Vladimir, Vasdev, Neil, Wadsak, Wolfgang, Zeglis, Brian M.
Published in Nuclear medicine and biology (01.02.2021)
Published in Nuclear medicine and biology (01.02.2021)
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Journal Article
Structure–Activity Relationship Studies of Pyridine-Based Ligands and Identification of a Fluorinated Derivative for Positron Emission Tomography Imaging of Cannabinoid Type 2 Receptors
Haider, Ahmed, Kretz, Julian, Gobbi, Luca, Ahmed, Hazem, Atz, Kenneth, Bürkler, Markus, Bartelmus, Christian, Fingerle, Jürgen, Guba, Wolfgang, Ullmer, Christoph, Honer, Michael, Knuesel, Irene, Weber, Markus, Brink, Andreas, Herde, Adrienne Müller, Keller, Claudia, Schibli, Roger, Mu, Linjing, Grether, Uwe, Ametamey, Simon M
Published in Journal of medicinal chemistry (26.12.2019)
Published in Journal of medicinal chemistry (26.12.2019)
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Journal Article
Novel chemoselective F-18-radiolabeling of thiol-containing biomolecules under mild aqueous conditions
Chiotellis, Aristeidis, Sladojevich, Filippo, Mu, Linjing, Herde, Adrienne Mueller, Valverde, Ibai E., Tolmachev, Vladimir, Schibli, Roger, Ametamey, Simon M., Mindt, Thomas L.
Published in Chemical communications (Cambridge, England) (01.01.2016)
Published in Chemical communications (Cambridge, England) (01.01.2016)
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Journal Article
Structure–Affinity Relationships of 2,3,4,5-Tetrahydro‑1H‑3-benzazepine and 6,7,8,9-Tetrahydro‑5H‑benzo[7]annulen-7-amine Analogues and the Discovery of a Radiofluorinated 2,3,4,5-Tetrahydro‑1H‑3-benzazepine Congener for Imaging GluN2B Subunit-Containing N‑Methyl‑d‑aspartate Receptors
Ahmed, Hazem, Haider, Ahmed, Varisco, Jasmine, Stanković, Maja, Wallimann, Rahel, Gruber, Stefan, Iten, Irina, Häne, Surya, Müller Herde, Adrienne, Keller, Claudia, Schibli, Roger, Schepmann, Dirk, Mu, Linjing, Wünsch, Bernhard, Ametamey, Simon M
Published in Journal of medicinal chemistry (14.11.2019)
Published in Journal of medicinal chemistry (14.11.2019)
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Journal Article
Structure-activity relationship of pyrazol-4-yl-pyridine derivatives for imaging the muscarinic acetylcholine receptor M4
Haider, Ahmed, Deng, Xiaoyun, Pfister, Stefanie, Jeppesen, Troels, Zhiwei, Xiao, Rong, Jian, Connors, Theresa, Collier, Thomas, Mu, Linjing, Schibli, Roger, Christopoulos, Arthur, Valant, Celine, Liang, Steven
Published in Nuclear medicine and biology (01.05.2022)
Published in Nuclear medicine and biology (01.05.2022)
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Journal Article