Antibody-mediated inhibition of GDF15–GFRAL activity reverses cancer cachexia in mice
Suriben, Rowena, Chen, Michael, Higbee, Jared, Oeffinger, Julie, Ventura, Richard, Li, Betty, Mondal, Kalyani, Gao, Zhengyu, Ayupova, Dina, Taskar, Pranali, Li, Diana, Starck, Shelley R., Chen, Hung-I Harry, McEntee, Michele, Katewa, Subhash D., Phung, Van, Wang, Marilyn, Kekatpure, Avantika, Lakshminarasimhan, Damodharan, White, Andre, Olland, Andrea, Haldankar, Raj, Solloway, Mark J., Hsu, Jer-Yuan, Wang, Yan, Tang, Jie, Lindhout, Darrin A., Allan, Bernard B.
Published in Nature medicine (01.08.2020)
Published in Nature medicine (01.08.2020)
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Non-homeostatic body weight regulation through a brainstem-restricted receptor for GDF15
Hsu, Jer-Yuan, Crawley, Suzanne, Chen, Michael, Ayupova, Dina A., Lindhout, Darrin A., Higbee, Jared, Kutach, Alan, Joo, William, Gao, Zhengyu, Fu, Diana, To, Carmen, Mondal, Kalyani, Li, Betty, Kekatpure, Avantika, Wang, Marilyn, Laird, Teresa, Horner, Geoffrey, Chan, Jackie, McEntee, Michele, Lopez, Manuel, Lakshminarasimhan, Damodharan, White, Andre, Wang, Sheng-Ping, Yao, Jun, Yie, Junming, Matern, Hugo, Solloway, Mark, Haldankar, Raj, Parsons, Thomas, Tang, Jie, Shen, Wenyan D., Alice Chen, Yu, Tian, Hui, Allan, Bernard B.
Published in Nature (London) (12.10.2017)
Published in Nature (London) (12.10.2017)
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Journal Article
Separating Tumorigenicity from Bile Acid Regulatory Activity for Endocrine Hormone FGF19
MEI ZHOU, XUEYAN WANG, LEARNED, R. Marc, DEPAOLI, Alex M, HUI TIAN, LEI LING, VAN PHUNG, LINDHOUT, Darrin A, MONDAL, Kalyani, HSU, Jer-Yuan, HONG YANG, HUMPHREY, Mark, XUNSHAN DING, ARORA, Taruna
Published in Cancer research (Chicago, Ill.) (15.06.2014)
Published in Cancer research (Chicago, Ill.) (15.06.2014)
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A nontumorigenic variant of FGF19 treats cholestatic liver diseases
Luo, Jian, Ko, Brian, Elliott, Michael, Zhou, Mei, Lindhout, Darrin A, Phung, Van, To, Carmen, Learned, R Marc, Tian, Hui, DePaoli, Alex M, Ling, Lei
Published in Science translational medicine (30.07.2014)
Published in Science translational medicine (30.07.2014)
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Translational insensitivity to potent activation of PKR by HCV IRES RNA
Shimoike, Takashi, McKenna, Sean A., Lindhout, Darrin A., Puglisi, Joseph D.
Published in Antiviral research (01.09.2009)
Published in Antiviral research (01.09.2009)
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Journal Article
Structural and Functional Characterization of Transmembrane Segment IV of the NHE1 Isoform of the Na+/H+ Exchanger
Slepkov, Emily R., Rainey, Jan K., Li, Xiuju, Liu, Yongsheng, Cheng, Florence J., Lindhout, Darrin A., Sykes, Brian D., Fliegel, Larry
Published in The Journal of biological chemistry (06.05.2005)
Published in The Journal of biological chemistry (06.05.2005)
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NMR solution structure of a highly stable de novo heterodimeric coiled-coil
Lindhout, Darrin A., Litowski, Jennifer R., Mercier, Pascal, Hodges, Robert S., Sykes, Brian D.
Published in Biopolymers (05.12.2004)
Published in Biopolymers (05.12.2004)
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Glucagon-receptor-antagonism-mediated β-cell regeneration as an effective anti-diabetic therapy
Xi, Yannan, Song, Benbo, Ngan, Iris, Solloway, Mark J., Humphrey, Mark, Wang, Yan, Mondal, Kalyani, Wu, Hao, Liu, Wenhui, Lindhout, Darrin A., Li, Diana, Matern, Hugo, Kekatpure, Avantika, Haldankar, Raj, Kaplan, Daniel D., Yang, Hong, Pedersen, Ophelia, Chen, Anna, Zhou, Mei, Winans, Bethany, Guo, Wei, Kutach, Alan, Fanget, Marie, Fox, Michael, Tang, Jie, Zha, Jiping, Younis, Husam, Shen, David, DePaoli, Alex, Tian, Hui, Liu, Zhonghao
Published in Cell reports (Cambridge) (31.05.2022)
Published in Cell reports (Cambridge) (31.05.2022)
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Journal Article
Purification and characterization of transcribed RNAs using gel filtration chromatography
Puglisi, Joseph D, McKenna, Sean A, Kim, Insil, Puglisi, Elisabetta Viani, Lindhout, Darrin A, Aitken, Colin Echeverría, Marshall, R Andrew
Published in Nature protocols (01.12.2007)
Published in Nature protocols (01.12.2007)
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Erratum: Non-homeostatic body weight regulation through a brainstem-restricted receptor for GDF15
Hsu, Jer-Yuan, Crawley, Suzanne, Chen, Michael, Ayupova, Dina A., Lindhout, Darrin A., Higbee, Jared, Kutach, Alan, Joo, William, Gao, Zhengyu, Fu, Diana, To, Carmen, Mondal, Kalyani, Li, Betty, Kekatpure, Avantika, Wang, Marilyn, Laird, Teresa, Horner, Geoffrey, Chan, Jackie, McEntee, Michele, Lopez, Manuel, Lakshminarasimhan, Damodharan, White, Andre, Wang, Sheng-Ping, Yao, Jun, Yie, Junming, Matern, Hugo, Solloway, Mark, Haldankar, Raj, Parsons, Thomas, Tang, Jie, Shen, Wenyan D., Alice Chen, Yu, Tian, Hui, Allan, Bernard B.
Published in Nature (London) (16.11.2017)
Published in Nature (London) (16.11.2017)
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Journal Article
High‐yield expression of isotopically labeled peptides for use in NMR studies
Lindhout, Darrin A., Thiessen, Angela, Schieve, Dean, Sykes, Brian D.
Published in Protein science (01.08.2003)
Published in Protein science (01.08.2003)
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The Role of Electrostatics in the Interaction of the Inhibitory Region of Troponin I with Troponin C
Lindhout, Darrin A, Boyko, Robert F, Corson, David C, Li, Monica X, Sykes, Brian D
Published in Biochemistry (Easton) (15.11.2005)
Published in Biochemistry (Easton) (15.11.2005)
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Journal Article
Phosphorylation and Mutation of Human Cardiac Troponin I Deferentially Destabilize the Interaction of the Functional Regions of Troponin I with Troponin C
Li, Monica X, Wang, Xu, Lindhout, Darrin A, Buscemi, Nina, Van Eyk, Jennifer E, Sykes, Brian D
Published in Biochemistry (Easton) (16.12.2003)
Published in Biochemistry (Easton) (16.12.2003)
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Journal Article
Effects of T142 Phosphorylation and Mutation R145G on the Interaction of the Inhibitory Region of Human Cardiac Troponin I with the C-Domain of Human Cardiac Troponin C
Lindhout, Darrin A, Li, Monica X, Schieve, Dean, Sykes, Brian D
Published in Biochemistry (Easton) (11.06.2002)
Published in Biochemistry (Easton) (11.06.2002)
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