Pyrazolone based TGFβR1 kinase inhibitors
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Published in Bioorganic & medicinal chemistry letters (2010)
Published in Bioorganic & medicinal chemistry letters (2010)
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Design, synthesis and identification of novel, orally bioavailable non-covalent Nrf2 activators
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Published in Bioorganic & medicinal chemistry letters (15.02.2020)
Published in Bioorganic & medicinal chemistry letters (15.02.2020)
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Stereochemistry–activity relationship of orally active tetralin S1P agonist prodrugs
Ma, Bin, Guckian, Kevin M., Lin, Edward Yin-Shiang, Lee, Wen-Cherng, Scott, Daniel, Kumaravel, Gnanasambandam, Macdonald, Timothy L., Lynch, Kevin R., Black, Cheryl, Chollate, Sowmya, Hahm, Kyungmin, Hetu, Gregg, Jin, Ping, Luo, Yi, Rohde, Ellen, Rossomando, Anthony, Scannevin, Robert, Wang, Joy, Yang, Chunhua
Published in Bioorganic & medicinal chemistry letters (01.04.2010)
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Development of a PET Tracer for OGA with Improved Kinetics in the Living Brain
Cook, Brendon E, Nag, Sangram, Arakawa, Ryosuke, Lin, Edward Yin-Shiang, Stratman, Nancy, Guckian, Kevin, Hering, Heike, Lulla, Mukesh, Choi, Jinkuk, Salinas, Cristian, Genung, Nathan E, Morén, Anton Forsberg, Bolin, Martin, Boscutti, Giulia, Plisson, Christophe, Martarello, Laurent, Halldin, Christer, Kaliszczak, Maciej A
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Published in Journal of Nuclear Medicine (01.10.2023)
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GIANATASSIO RYAN, ZHANG LEI, GUCKIAN KEVIN M, XIN ZHILI, VESSELS JEFFREY, GENUNG NATHAN, LIN EDWARD YIN SHIANG
Year of Publication 26.05.2021
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Year of Publication 26.05.2021
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Year of Publication 16.08.2023
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Year of Publication 16.08.2023
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NRF2 활성화제
LUCAS BRIAN STUART, CAPACCI ANDREW GEORGE, ENYEDY ISTVAN, CHEN TEYU, VAN VLOTEN KURT D, XIN ZHILI, JONES JOHN H, LIN EDWARD YIN SHIANG
Year of Publication 02.10.2019
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Year of Publication 02.10.2019
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BICYCLIC ARYL SPHINGOSINE 1-PHOSPHATE ANALOGS
BIN MA, GNANASAMBANDAM KUMARAVEL, JERMAINE THOMAS, KEVIN M GUCKIAN, ZHENG GUO ZHU, TAVERAS ARTHUR G, LIN EDWARD YIN-SHIANG, RICHARD D CALDWELL, LIU XIAOGAO
Year of Publication 09.08.2018
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Year of Publication 09.08.2018
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Heterocyclic Compounds Useful as PDK1 Inhibitors
LEE WEN CHERNG, VAN VLOTEN KURT, ZHANG LEI, GUCKIAN KEVIN, ARNDT JOSEPH, THOMAS JERMAINE, CHAN TIMOTHY, LIN EDWARD YIN SHIANG, SCOTT DANIEL, KUMARAVEL GNANASAMBANDAM, WANG DEPING, SUN LIHONG, ERLANSON DANIEL
Year of Publication 11.03.2019
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Year of Publication 11.03.2019
Patent
Heterocyclic Compounds Useful as PDK1 Inhibitors
LEE WEN CHERNG, VAN VLOTEN KURT, ZHANG LEI, GUCKIAN KEVIN, ARNDT JOSEPH, THOMAS JERMAINE, CHAN TIMOTHY, LIN EDWARD YIN SHIANG, SCOTT DANIEL, KUMARAVEL GNANASAMBANDAM, WANG DEPING, SUN LIHONG, ERLANSON DANIEL
Year of Publication 28.12.2017
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Year of Publication 28.12.2017
Patent
BICYCLIC ARYL SPHINGOSINE 1-PHOSPHATE ANALOGS
BIN MA, GNANASAMBANDAM KUMARAVEL, JERMAINE THOMAS, KEVIN M GUCKIAN, ZHENG GUO ZHU, TAVERAS ARTHUR G, LIN EDWARD YIN-SHIANG, RICHARD D CALDWELL, LIU XIAOGAO
Year of Publication 01.09.2016
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Year of Publication 01.09.2016
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S1P MODULATING AGENTS
MI SHA, KUMARAVEL GNANASAMBANDAM, MA BIN, ZHENG GUO ZHU, GUCKIAN KEVIN, CALDWELL RICHARD D, THOMAS JERMAINE, LIN EDWARD YIN SHIANG
Year of Publication 20.03.2014
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Year of Publication 20.03.2014
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Structure–activity relationship of ortho- and meta-phenol based LFA-1 ICAM inhibitors
Lin, Edward Yin-Shiang, Guckian, Kevin M., Silvian, Laura, Chin, Donovan, Ann Boriack-Sjodin, P., van Vlijmen, Herman, Friedman, Jessica E., Scott, Daniel M.
Published in Bioorganic & medicinal chemistry (01.10.2008)
Published in Bioorganic & medicinal chemistry (01.10.2008)
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BICYCLIC ARYL SPHINGOSINE 1-PHOSPHATE ANALOGS
KUMARAVEL GNANASAMBANDAM, GUCKIAN KEVIN M, MA BIN, ZHENG GUO ZHU, TAVERAS ARTHUR G, CALDWELL RICHARD D, THOMAS JERMAINE, LIN EDWARD YIN SHIANG, LIU XIAOGAO
Year of Publication 22.05.2012
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Year of Publication 22.05.2012
Patent
HETEROCYCLIC COMPOUNDS USEFUL AS PDK1 INHIBITORS
LEE WEN CHERNG, VAN VLOTEN KURT, ZHANG LEI, GUCKIAN KEVIN, ARNDT JOSEPH, THOMAS JERMAINE, CHAN TIMOTHY, LIN EDWARD YIN SHIANG, SCOTT DANIEL, KUMARAVEL GNANASAMBANDAM, WANG DEPING, SUN LIHONG, ERLANSON DANIEL
Year of Publication 07.08.2012
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Year of Publication 07.08.2012
Patent
Development of a PET Tracer for OGA with Improved Kinetics in the Living Brain
Cook, Brendon E, Nag, Sangram, Arakawa, Ryosuke, Lin, Edward Yin-Shiang, Stratman, Nancy, Guckian, Kevin, Hering, Heike, Lulla, Mukesh, Choi, Jinkuk, Salinas, Cristian, Genung, Nathan E, Morén, Anton Forsberg, Bolin, Martin, Boscutti, Giulia, Plisson, Christophe, Martarello, Laurent, Halldin, Christer, Kaliszczak, Maciej A
Published in The Journal of nuclear medicine (1978) (01.10.2023)
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Published in The Journal of nuclear medicine (1978) (01.10.2023)
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Pyrazolone based TGFbR1 kinase inhibitors
Guckian, Kevin, Carter, Mary Beth, Lin, Edward Yin-Shiang, Choi, Michael, Sun, Lihong, Boriack-Sjodin, PAnn, Chuaqui, Claudio, Lane, Benjamin, Cheung, Kam, Ling, Leona, Lee, Wen-Cherng
Published in Bioorganic & medicinal chemistry letters (01.01.2010)
Published in Bioorganic & medicinal chemistry letters (01.01.2010)
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O-glycoprotein-2-acetamido-2-deoxy-3-D-glycopyranosidase inhibitors
GUCKIAN, Kevin M, ZHANG, Lei, LIN, Edward Yin Shiang, GENUNG, Nathan, GIANATASSIO, Ryan, VESSELS, Jeffrey, XIN, Zhili
Year of Publication 01.08.2024
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Year of Publication 01.08.2024
Patent