Development of glycosynthases with broad glycan specificity for the efficient glyco-remodeling of antibodies
Shivatare, Sachin S, Huang, Lin-Ya, Zeng, Yi-Fang, Liao, Jung-Yu, You, Tsai-Hong, Wang, Shi-Yun, Cheng, Ting, Chiu, Chih-Wei, Chao, Ping, Chen, Li-Tzu, Tsai, Tsung-I, Huang, Chiu-Chen, Wu, Chung-Yi, Lin, Nan-Horng, Wong, Chi-Huey
Published in Chemical communications (Cambridge, England) (2018)
Published in Chemical communications (Cambridge, England) (2018)
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An Effective Bacterial Fucosidase for Glycoprotein Remodeling
Tsai, Tsung-I, Li, Shiou-Ting, Liu, Chiu-Ping, Chen, Karen Y, Shivatare, Sachin S, Lin, Chin-Wei, Liao, Shih-Fen, Lin, Chih-Wei, Hsu, Tsui-Ling, Wu, Ying-Ta, Tsai, Ming-Hung, Lai, Meng-Yu, Lin, Nan-Horng, Wu, Chung-Yi, Wong, Chi-Huey
Published in ACS chemical biology (20.01.2017)
Published in ACS chemical biology (20.01.2017)
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Selective Chk1 inhibitors differentially sensitize p53‐deficient cancer cells to cancer therapeutics
Chen, Zehan, Xiao, Zhan, Gu, Wen‐zhen, Xue, John, Bui, Mai H., Kovar, Peter, Li, Gaoquan, Wang, Gary, Tao, Zhi‐Fu, Tong, Yunsong, Lin, Nan‐Horng, Sham, Hing L., Wang, Jean Y. J., Sowin, Thomas J., Rosenberg, Saul H., Zhang, Haiying
Published in International journal of cancer (15.12.2006)
Published in International journal of cancer (15.12.2006)
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Structure-Based Design, Synthesis, and Biological Evaluation of Potent and Selective Macrocyclic Checkpoint Kinase 1 Inhibitors
Tao, Zhi-Fu, Wang, Le, Stewart, Kent D, Chen, Zehan, Gu, Wendy, Bui, Mai-Ha, Merta, Philip, Zhang, Haiying, Kovar, Peter, Johnson, Eric, Park, Chang, Judge, Russell, Rosenberg, Saul, Sowin, Thomas, Lin, Nan-Horng
Published in Journal of medicinal chemistry (05.04.2007)
Published in Journal of medicinal chemistry (05.04.2007)
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Design, Synthesis, and Biological Activity of 5,10-Dihydro-dibenzo[b,e][1,4]diazepin-11-one-Based Potent and Selective Chk-1 Inhibitors
Wang, Le, Sullivan, Gerard M, Hexamer, Laura A, Hasvold, Lisa A, Thalji, Reema, Przytulinska, Magdalena, Tao, Zhi-Fu, Li, Gaoquan, Chen, Zehan, Xiao, Zhan, Gu, Wen-Zhen, Xue, John, Bui, Mai-Ha, Merta, Philip, Kovar, Peter, Bouska, Jennifer J, Zhang, Haiying, Park, Chang, Stewart, Kent D, Sham, Hing L, Sowin, Thomas J, Rosenberg, Saul H, Lin, Nan-Horng
Published in Journal of medicinal chemistry (23.08.2007)
Published in Journal of medicinal chemistry (23.08.2007)
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A common glycan structure on immunoglobulin G for enhancement of effector functions
Lin, Chin-Wei, Tsai, Ming-Hung, Li, Shiou-Ting, Tsai, Tsung-I, Chu, Kuo-Ching, Liu, Ying-Chih, Lai, Meng-Yu, Wu, Chia-Yu, Tseng, Yung-Chieh, Shivatare, Sachin S., Wang, Chia-Hung, Chao, Ping, Wang, Shi-Yun, Shih, Hao-Wei, Zeng, Yi-Fang, You, Tsai-Hong, Liao, Jung-Yu, Tu, Yu-Chen, Lin, Yih-Shyan, Chuang, Hong-Yang, Chen, Chia-Lin, Tsai, Charng-Sheng, Huang, Chiu-Chen, Lin, Nan-Horng, Ma, Che, Wu, Chung-Yi, Wong, Chi-Huey
Published in Proceedings of the National Academy of Sciences - PNAS (25.08.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (25.08.2015)
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Discovery of 4′-(1,4-dihydro-indeno[1,2- c]pyrazol-3-yl)-benzonitriles and 4′-(1,4-dihydro-indeno[1,2- c]pyrazol-3-yl)-pyridine-2′-carbonitriles as potent checkpoint kinase 1 (Chk1) inhibitors
Tao, Zhi-Fu, Li, Gaoquan, Tong, Yunsong, Stewart, Kent D., Chen, Zehan, Bui, Mai-Ha, Merta, Philip, Park, Chang, Kovar, Peter, Zhang, Haiying, Sham, Hing L., Rosenberg, Saul H., Sowin, Thomas J., Lin, Nan-Horng
Published in Bioorganic & medicinal chemistry letters (01.11.2007)
Published in Bioorganic & medicinal chemistry letters (01.11.2007)
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Journal Article
Synthesis and biological evaluation of 4′-(6,7-disubstituted-2,4-dihydro-indeno[1,2- c]pyrazol-3-yl)-biphenyl-4-ol as potent Chk1 inhibitors
Tao, Zhi-Fu, Li, Gaoquan, Tong, Yunsong, Chen, Zehan, Merta, Philip, Kovar, Peter, Zhang, Haiying, Rosenberg, Saul H., Sham, Hing L., Sowin, Thomas J., Lin, Nan-Horng
Published in Bioorganic & medicinal chemistry letters (01.08.2007)
Published in Bioorganic & medicinal chemistry letters (01.08.2007)
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Journal Article
Unprecedented Role of Hybrid N-Glycans as Ligands for HIV‑1 Broadly Neutralizing Antibodies
Shivatare, Vidya S, Shivatare, Sachin S, Lee, Chang-Chun David, Liang, Chi-Hui, Liao, Kuo-Shiang, Cheng, Yang-Yu, Saidachary, Gannerla, Wu, Chung-Yi, Lin, Nan-Horng, Kwong, Peter D, Burton, Dennis R, Wu, Chung-Yi, Wong, Chi-Huey
Published in Journal of the American Chemical Society (18.04.2018)
Published in Journal of the American Chemical Society (18.04.2018)
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Synthesis and biological evaluation of 1-(2,4,5-trisubstituted phenyl)-3-(5-cyanopyrazin-2-yl)ureas as potent Chk1 kinase inhibitors
Li, Gaoquan, Hasvold, Lisa A., Tao, Zhi-Fu, Wang, Gary T., Gwaltney, Stephen L., Patel, Jyoti, Kovar, Peter, Credo, Robert B., Chen, Zehan, Zhang, Haiying, Park, Chang, Sham, Hing L., Sowin, Thomas, Rosenberg, Saul H., Lin, Nan-Horng
Published in Bioorganic & medicinal chemistry letters (15.04.2006)
Published in Bioorganic & medicinal chemistry letters (15.04.2006)
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Journal Article
Synthesis and in-vitro biological activity of macrocyclic urea Chk1 inhibitors
Li, Gaoquan, Tao, Zhi-Fu, Tong, Yunsong, Przytulinska, Magdalena K., Kovar, Peter, Merta, Philip, Chen, Zehan, Zhang, Haiying, Sowin, Thomas, Rosenberg, Saul H., Lin, Nan-Horng
Published in Bioorganic & medicinal chemistry (01.12.2007)
Published in Bioorganic & medicinal chemistry (01.12.2007)
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Antitumor Activity of Orally Bioavailable Farnesyltransferase Inhibitor, ABT-100, Is Mediated by Antiproliferative, Proapoptotic, and Antiangiogenic Effects in Xenograft Models
Ferguson, Debra, Rodriguez, Luis E, Palma, Joann P, Refici, Marion, Jarvis, Kenneth, O'Connor, Jacqueline, Sullivan, Gerard M, Frost, David, Marsh, Kennan, Bauch, Joy, Zhang, Haiying, Lin, Nan-Horng, Rosenberg, Saul, Sham, Hing L, Joseph, Ingrid B J K
Published in Clinical cancer research (15.04.2005)
Published in Clinical cancer research (15.04.2005)
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Development of biotinylated and magnetic bead-immobilized enzymes for efficient glyco-engineering and isolation of antibodies
Chuang, Hong-Yang, Huang, Chiu-Chen, Hung, Ting-Chun, Huang, Lin-Ya, Chiu, Chih-Wei, Chu, Kuo-Ching, Liao, Jung-Yu, You, Tsai-Hong, Wu, Chung-Yi, Chao, Ping, Shivatare, Sachin S., Zeng, Yi-Fang, Tsai, Charng-Sheng, Lin, Nan-Horng, Wu, Chung-Yi
Published in Bioorganic chemistry (01.07.2021)
Published in Bioorganic chemistry (01.07.2021)
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Journal Article
Correction: Development of glycosynthases with broad glycan specificity for the efficient glyco-remodeling of antibodies
Shivatare, Sachin S, Huang, Lin-Ya, Zeng, Yi-Fang, Liao, Jung-Yu, You, Tsai-Hong, Wang, Shi-Yun, Cheng, Ting, Chiu, Chih-Wei, Chao, Ping, Chen, Li-Tzu, Tsai, Tsung-I, Huang, Chiu-Chen, Wu, Chung-Yi, Lin, Nan-Horng, Wong, Chi-Huey
Published in Chemical communications (Cambridge, England) (10.07.2018)
Published in Chemical communications (Cambridge, England) (10.07.2018)
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Phenyl Glycolipids with Different Glycosyl Groups Exhibit Marked Differences in Murine and Human iNKT Cell Activation
Wu, Tai-Na, Lin, Kun-Hsien, Wu, Ying-Ta, Huang, Jing-Rong, Hung, Jung-Tung, Wu, Jen-Chine, Chen, Chien-Yu, Chu, Kuo-Ching, Lin, Nan-Horng, Yu, Alice L, Wong, Chi-Huey
Published in ACS chemical biology (16.12.2016)
Published in ACS chemical biology (16.12.2016)
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Discovery of 3H-Benzo[4,5]thieno[3,2-d]pyrimidin-4-ones as Potent, Highly Selective, and Orally Bioavailable Inhibitors of the Human Protooncogene Proviral Insertion Site in Moloney Murine Leukemia Virus (PIM) Kinases
Tao, Zhi-Fu, Hasvold, Lisa A, Leverson, Joel D, Han, Edward K, Guan, Ran, Johnson, Eric F, Stoll, Vincent S, Stewart, Kent D, Stamper, Geoff, Soni, Nirupama, Bouska, Jennifer J, Luo, Yan, Sowin, Thomas J, Lin, Nan-Horng, Giranda, Vincent S, Rosenberg, Saul H, Penning, Thomas D
Published in Journal of medicinal chemistry (12.11.2009)
Published in Journal of medicinal chemistry (12.11.2009)
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Journal Article
ABT-089 [2-Methyl-3-(2-(S)-pyrrolidinylmethoxy)pyridine]: I. A Potent and Selective Cholinergic Channel Modulator with Neuroprotective Properties
Sullivan, J P, Donnelly-Roberts, D, Briggs, C A, Anderson, D J, Gopalakrishnan, M, Xue, I C, Piattoni-Kaplan, M, Molinari, E, Campbell, J E, McKenna, D G, Gunn, D E, Lin, N H, Ryther, K B, He, Y, Holladay, M W, Wonnacott, S, Williams, M, Arneric, S P
Published in The Journal of pharmacology and experimental therapeutics (01.10.1997)
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Published in The Journal of pharmacology and experimental therapeutics (01.10.1997)
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ABT-089 [2-Methyl-3-(2-(S)-pyrrolidinylmethoxy)pyridine dihydrochloride]: II. A Novel Cholinergic Channel Modulator with Effects on Cognitive Performance in Rats and Monkeys
Decker, M W, Bannon, A W, Curzon, P, Gunther, K L, Brioni, J D, Holladay, M W, Lin, N H, Li, Y, Daanen, J F, Buccafusco, J J, Prendergast, M A, Jackson, W J, Arneric, S P
Published in The Journal of pharmacology and experimental therapeutics (01.10.1997)
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Published in The Journal of pharmacology and experimental therapeutics (01.10.1997)
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Isoxazolo[3,4- b]quinoline-3,4(1H,9H)-diones as unique, potent and selective inhibitors for Pim-1 and Pim-2 kinases: Chemistry, biological activities, and molecular modeling
Tong, Yunsong, Stewart, Kent D., Thomas, Sheela, Przytulinska, Magdalena, Johnson, Eric F., Klinghofer, Vered, Leverson, Joel, McCall, Owen, Soni, Niru B., Luo, Yan, Lin, Nan-horng, Sowin, Thomas J., Giranda, Vincent L., Penning, Thomas D.
Published in Bioorganic & medicinal chemistry (01.10.2008)
Published in Bioorganic & medicinal chemistry (01.10.2008)
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