Development of resistance to FAK inhibition in pancreatic cancer is linked to stromal depletion
Jiang, Hong, Liu, Xiuting, Knolhoff, Brett L, Hegde, Samarth, Lee, Kyung Bae, Jiang, Hongmei, Fields, Ryan C, Pachter, Jonathan A, Lim, Kian-Huat, DeNardo, David G
Published in Gut (01.01.2020)
Published in Gut (01.01.2020)
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Journal Article
Targeting tumour-associated macrophages with CCR2 inhibition in combination with FOLFIRINOX in patients with borderline resectable and locally advanced pancreatic cancer: a single-centre, open-label, dose-finding, non-randomised, phase 1b trial
Nywening, Timothy M, MD, Wang-Gillam, Andrea, MD, Sanford, Dominic E, MD, Belt, Brian A, MA, Panni, Roheena Z, MD, Cusworth, Brian M, BA, Toriola, Adetunji T, MD, Nieman, Rebecca K, MS, Worley, Lori A, BS, Yano, Motoyo, MD, Fowler, Kathryn J, MD, Lockhart, A Craig, MD, Suresh, Rama, MD, Tan, Benjamin R, MD, Lim, Kian-Huat, MD, Fields, Ryan C, MD, Strasberg, Steven M, Prof, Hawkins, William G, Prof, DeNardo, David G, PhD, Goedegebuure, S Peter, PhD, Linehan, David C, Dr Prof
Published in The lancet oncology (01.05.2016)
Published in The lancet oncology (01.05.2016)
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Journal Article
Advanced pancreatic adenocarcinoma: a review of current treatment strategies and developing therapies
Teague, Andrea, Lim, Kian-Huat, Wang-Gillam, Andrea
Published in Therapeutic Advances in Medical Oncology (01.03.2015)
Published in Therapeutic Advances in Medical Oncology (01.03.2015)
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Book Review
Journal Article
Oncogenic Ras-induced secretion of IL6 is required for tumorigenesis
Ancrile, Brooke, Lim, Kian-Huat, Counter, Christopher M
Published in Genes & development (15.07.2007)
Published in Genes & development (15.07.2007)
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Journal Article
RALA and RALBP1 regulate mitochondrial fission at mitosis
Lim, Kian-Huat, Counter, Christopher M, Kashatus, David F, Brady, Donita C, Pershing, Nicole L. K, Cox, Adrienne D
Published in Nature cell biology (01.09.2011)
Published in Nature cell biology (01.09.2011)
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Journal Article
Oncogenically active MYD88 mutations in human lymphoma
Ngo, Vu N., Young, Ryan M., Schmitz, Roland, Jhavar, Sameer, Xiao, Wenming, Lim, Kian-Huat, Kohlhammer, Holger, Xu, Weihong, Yang, Yandan, Zhao, Hong, Shaffer, Arthur L., Romesser, Paul, Wright, George, Powell, John, Rosenwald, Andreas, Muller-Hermelink, Hans Konrad, Ott, German, Gascoyne, Randy D., Connors, Joseph M., Rimsza, Lisa M., Campo, Elias, Jaffe, Elaine S., Delabie, Jan, Smeland, Erlend B., Fisher, Richard I., Braziel, Rita M., Tubbs, Raymond R., Cook, J. R., Weisenburger, Denny D., Chan, Wing C., Staudt, Louis M.
Published in Nature (London) (03.02.2011)
Published in Nature (London) (03.02.2011)
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Journal Article
Constitutive IRAK4 Activation Underlies Poor Prognosis and Chemoresistance in Pancreatic Ductal Adenocarcinoma
Zhang, Daoxiang, Li, Lin, Jiang, Hongmei, Knolhoff, Brett L, Lockhart, Albert C, Wang-Gillam, Andrea, DeNardo, David G, Ruzinova, Marianna B, Lim, Kian-Huat
Published in Clinical cancer research (01.04.2017)
Published in Clinical cancer research (01.04.2017)
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Journal Article
Concurrent HER or PI3K Inhibition Potentiates the Antitumor Effect of the ERK Inhibitor Ulixertinib in Preclinical Pancreatic Cancer Models
Jiang, Hongmei, Xu, Mai, Li, Lin, Grierson, Patrick, Dodhiawala, Paarth, Highkin, Maureen, Zhang, Daoxiang, Li, Qiong, Wang-Gillam, Andrea, Lim, Kian-Huat
Published in Molecular cancer therapeutics (01.10.2018)
Published in Molecular cancer therapeutics (01.10.2018)
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Journal Article
Neoadjuvant Therapy of Pancreatic Cancer: The Emerging Paradigm?
Lim, Kian‐Huat, Chung, Eugene, Khan, Adeel, Cao, Dengfeng, Linehan, David, Ben‐Josef, Edgar, Wang‐Gillam, Andrea
Published in The oncologist (Dayton, Ohio) (01.02.2012)
Published in The oncologist (Dayton, Ohio) (01.02.2012)
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Journal Article
The Cytoplasmic Deacetylase HDAC6 Is Required for Efficient Oncogenic Tumorigenesis
LEE, Yi-Shan, LIM, Kian-Huat, XING GUO, KAWAGUCHI, Yoshiharu, YASHENG GAO, BARRIENTOS, Tomasa, ORDENTLICH, Peter, WANG, Xiao-Fan, COUNTER, Christopher M, YAO, Tso-Pang
Published in Cancer research (Chicago, Ill.) (15.09.2008)
Published in Cancer research (Chicago, Ill.) (15.09.2008)
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Journal Article
Combined KRAS-MAPK pathway inhibitors and HER2-directed drug conjugate is efficacious in pancreatic cancer
Bulle, Ashenafi, Liu, Peng, Seehra, Kuljeet, Bansod, Sapana, Chen, Yali, Zahra, Kiran, Somani, Vikas, Khawar, Iftikhar Ali, Chen, Hung-Po, Dodhiawala, Paarth B., Li, Lin, Geng, Yutong, Mo, Chia-Kuei, Mahsl, Jay, Ding, Li, Govindan, Ramaswamy, Davies, Sherri, Mudd, Jacqueline, Hawkins, William G., Fields, Ryan C., DeNardo, David G., Knoerzer, Deborah, Held, Jason M., Grierson, Patrick M., Wang-Gillam, Andrea, Ruzinova, Marianna B., Lim, Kian-Huat
Published in Nature communications (20.03.2024)
Published in Nature communications (20.03.2024)
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Journal Article
Distinct clinical and magnetic resonance features of metastatic hepatocellular carcinoma treated with pembrolizumab: A case report of late response after pseudoprogression
Grierson, Patrick, Crites, Danielle, Ruzinova, Marianna B., Yano, Motoyo, Lim, Kian‐Huat
Published in Hepatology communications (01.02.2018)
Published in Hepatology communications (01.02.2018)
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Journal Article