Structural mechanism of ligand activation in human GABAB receptor
Geng, Yong, Bush, Martin, Mosyak, Lidia, Wang, Feng, Fan, Qing R.
Published in Nature (London) (12.12.2013)
Published in Nature (London) (12.12.2013)
Get full text
Journal Article
Structural mechanism of ligand activation in human calcium-sensing receptor
Geng, Yong, Mosyak, Lidia, Kurinov, Igor, Zuo, Hao, Sturchler, Emmanuel, Cheng, Tat Cheung, Subramanyam, Prakash, Brown, Alice P, Brennan, Sarah C, Mun, Hee-Chang, Bush, Martin, Chen, Yan, Nguyen, Trang X, Cao, Baohua, Chang, Donald D, Quick, Matthias, Conigrave, Arthur D, Colecraft, Henry M, McDonald, Patricia, Fan, Qing R
Published in eLife (19.07.2016)
Published in eLife (19.07.2016)
Get full text
Journal Article
Crystal structure of ultra-humanized anti-pTau Fab reveals how germline substitutions humanize CDRs without loss of binding
Brinth, Alette R., Svenson, Kristine, Mosyak, Lidia, Cunningham, Orla, Hickling, Timothy, Lambert, Matthew
Published in Scientific reports (24.05.2022)
Published in Scientific reports (24.05.2022)
Get full text
Journal Article
Structure of human GABAB receptor in an inactive state
Park, Jinseo, Fu, Ziao, Frangaj, Aurel, Liu, Jonathan, Mosyak, Lidia, Shen, Tong, Slavkovich, Vesna N., Ray, Kimberly M., Taura, Jaume, Cao, Baohua, Geng, Yong, Zuo, Hao, Kou, Yongjun, Grassucci, Robert, Chen, Shaoxia, Liu, Zheng, Lin, Xin, Williams, Justin P., Rice, William J., Eng, Edward T., Huang, Rick K., Soni, Rajesh K., Kloss, Brian, Yu, Zhiheng, Javitch, Jonathan A., Hendrickson, Wayne A., Slesinger, Paul A., Quick, Matthias, Graziano, Joseph, Yu, Hongtao, Fiehn, Oliver, Clarke, Oliver B., Frank, Joachim, Fan, Qing R.
Published in Nature (London) (13.08.2020)
Published in Nature (London) (13.08.2020)
Get full text
Journal Article
Fc-GDF15 glyco-engineering and receptor binding affinity optimization for body weight regulation
Fung, Ella, Kang, Liya, Sapashnik, Diana, Benard, Susan, Sievers, Annette, Liu, Yan, Yan, Guoying, Zhou, Jing, Rodriguez, Linette, Ma, Weijun, Stochaj, Wayne R., LaVallie, Edward, Wroblewska, Liliana, Kelleher, Kerry, Tam, Amy, Bezy, Olivier, Breen, Danna, Chabot, Jeffrey R., He, Tao, Lin, Laura, Wu, Zhidan, Mosyak, Lidia
Published in Scientific reports (26.04.2021)
Published in Scientific reports (26.04.2021)
Get full text
Journal Article
Symmetric activation and modulation of the human calcium-sensing receptor
Park, Jinseo, Zuo, Hao, Frangaj, Aurel, Fu, Ziao, Yen, Laura Y., Zhang, Zhening, Mosyak, Lidia, Slavkovich, Vesna N., Liu, Jonathan, Ray, Kimberly M., Cao, Baohua, Vallese, Francesca, Geng, Yong, Chen, Shaoxia, Grassucci, Robert, Dandey, Venkata P., Tan, Yong Zi, Eng, Edward, Lee, Yeji, Kloss, Brian, Liu, Zheng, Hendrickson, Wayne A., Potter, Clinton S., Carragher, Bridget, Graziano, Joseph, Conigrave, Arthur D., Frank, Joachim, Clarke, Oliver B., Fan, Qing R.
Published in Proceedings of the National Academy of Sciences - PNAS (21.12.2021)
Published in Proceedings of the National Academy of Sciences - PNAS (21.12.2021)
Get full text
Journal Article
Tyrosine Sulfation at Antibody Light Chain CDR-1 Increases Binding Affinity and Neutralization Potency to Interleukine-4
D'Antona, Aaron M, Lee, Julie M, Zhang, Melvin, Friedman, Clarence, He, Tao, Mosyak, Lidia, Bennett, Eric, Lin, Laura, Silverman, Maddison, Cometa, Funi, Meade, Caryl, Hageman, Tyler, Sousa, Eric, Cohen, Justin, Marquette, Kimberly, Ferguson, Darren, Zhong, Xiaotian
Published in International journal of molecular sciences (01.02.2024)
Published in International journal of molecular sciences (01.02.2024)
Get full text
Journal Article
High Resolution Mapping of Bactericidal Monoclonal Antibody Binding Epitopes on Staphylococcus aureus Antigen MntC
Gribenko, Alexey V, Parris, Kevin, Mosyak, Lidia, Li, Sheng, Handke, Luke, Hawkins, Julio C, Severina, Elena, Matsuka, Yury V, Anderson, Annaliesa S
Published in PLoS pathogens (01.09.2016)
Published in PLoS pathogens (01.09.2016)
Get full text
Journal Article
Engineering a Monomeric Fc Domain Modality by N-Glycosylation for the Half-life Extension of Biotherapeutics
Ishino, Tetsuya, Wang, Mengmeng, Mosyak, Lidia, Tam, Amy, Duan, Weili, Svenson, Kristine, Joyce, Alison, O'Hara, Denise M., Lin, Laura, Somers, William S., Kriz, Ronald
Published in The Journal of biological chemistry (07.06.2013)
Published in The Journal of biological chemistry (07.06.2013)
Get full text
Journal Article
Structure and functional interaction of the extracellular domain of human GABAB receptor GBR2
Geng, Yong, Xiong, Dazhi, Mosyak, Lidia, Malito, David L, Kniazeff, Julie, Chen, Yan, Burmakina, Svetlana, Quick, Matthias, Bush, Martin, Javitch, Jonathan A, Pin, Jean-Philippe, Fan, Qing R
Published in Nature neuroscience (03.06.2012)
Published in Nature neuroscience (03.06.2012)
Get full text
Journal Article
Crystal structures of the two major aggrecan degrading enzymes, ADAMTS4 and ADAMTS5
Mosyak, Lidia, Georgiadis, Katy, Shane, Tania, Svenson, Kristine, Hebert, Tracy, McDonagh, Thomas, Mackie, Stewart, Olland, Stephane, Lin, Laura, Zhong, Xiaotian, Kriz, Ronald, Reifenberg, Erica L., Collins‐Racie, Lisa A., Corcoran, Christopher, Freeman, Bethany, Zollner, Richard, Marvell, Tod, Vera, Matthew, Sum, Phaik‐Eng, Lavallie, Edward R., Stahl, Mark, Somers, William
Published in Protein science (01.01.2008)
Published in Protein science (01.01.2008)
Get full text
Journal Article
Triad of polar residues implicated in pH specificity of acidic mammalian chitinase
Olland, Andrea M., Strand, James, Presman, Eleonora, Czerwinski, Robert, Joseph‐McCarthy, Diane, Krykbaev, Rustem, Schlingmann, Gerhard, Chopra, Rajiv, Lin, Laura, Fleming, Margaret, Kriz, Ron, Stahl, Mark, Somers, William, Fitz, Lori, Mosyak, Lidia
Published in Protein science (01.03.2009)
Published in Protein science (01.03.2009)
Get full text
Journal Article
The Structure of the Lingo-1 Ectodomain, a Module Implicated in Central Nervous System Repair Inhibition
Mosyak, Lidia, Wood, Andrew, Dwyer, Brian, Buddha, Madhavan, Johnson, Mark, Aulabaugh, Ann, Zhong, Xiaotian, Presman, Eleonora, Benard, Susan, Kelleher, Kerry, Wilhelm, James, Stahl, Mark L., Kriz, Ron, Gao, Ying, Cao, Zixuan, Ling, Huai-Ping, Pangalos, Menelas N., Walsh, Frank S., Somers, William S.
Published in The Journal of biological chemistry (24.11.2006)
Published in The Journal of biological chemistry (24.11.2006)
Get full text
Journal Article
Design and synthesis of indolo[2,3- a]quinolizin-7-one inhibitors of the ZipA–FtsZ interaction
Jennings, Lee D., Foreman, Ken W., Rush, Thomas S., Tsao, Desiree H.H., Mosyak, Lidia, Li, Yuanhong, Sukhdeo, Mohani N., Ding, Weidong, Dushin, Elizabeth G., Kenny, Cynthia Hess, Moghazeh, Soraya L., Petersen, Peter J., Ruzin, Alexey V., Tuckman, Margareta, Sutherland, Alan G.
Published in Bioorganic & medicinal chemistry letters (22.03.2004)
Published in Bioorganic & medicinal chemistry letters (22.03.2004)
Get full text
Journal Article
Structure of human GABA.sub.B receptor in an inactive state
Park, Jinseo, Fu, Ziao, Frangaj, Aurel, Liu, Jonathan, Mosyak, Lidia, Shen, Tong, Slavkovich, Vesna N
Published in Nature (London) (13.08.2020)
Published in Nature (London) (13.08.2020)
Get full text
Journal Article
Author Correction: Structure of human GABA.sub.B receptor in an inactive state
Park, Jinseo, Fu, Ziao, Frangaj, Aurel, Liu, Jonathan, Mosyak, Lidia, Shen, Tong, Slavkovich, Vesna N
Published in Nature (London) (30.07.2020)
Published in Nature (London) (30.07.2020)
Get full text
Journal Article
Structural basis for auxiliary subunit KCTD16 regulation of the GABAB receptor
Zuo, Hao, Glaaser, Ian, Zhao, Yulin, Kurinov, Igor, Mosyak, Lidia, Wang, Haonan, Liu, Jonathan, Park, Jinseo, Frangaj, Aurel, Sturchler, Emmanuel, Zhou, Ming, McDonald, Patricia, Geng, Yong, Slesinger, Paul A., Fan, Qing R.
Published in Proceedings of the National Academy of Sciences - PNAS (23.04.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (23.04.2019)
Get full text
Journal Article