Bromodomain inhibitors, JQ1 and I-BET 762, as potential therapies for pancreatic cancer
Leal, Ana S, Williams, Charlotte R, Royce, Darlene B, Pioli, Patricia A, Sporn, Michael B, Liby, Karen T
Published in Cancer letters (28.05.2017)
Published in Cancer letters (28.05.2017)
Get full text
Journal Article
A Novel Nrf2 Pathway Inhibitor Sensitizes Keap1-Mutant Lung Cancer Cells to Chemotherapy
Zhang, Di, Hou, Zhilin, Aldrich, Kelly E, Lockwood, Lizbeth, Odom, Aaron L, Liby, Karen T
Published in Molecular cancer therapeutics (01.09.2021)
Published in Molecular cancer therapeutics (01.09.2021)
Get full text
Journal Article
Proteomic analysis shows synthetic oleanane triterpenoid binds to mTOR
Yore, Mark M, Kettenbach, Arminja N, Sporn, Michael B, Gerber, Scott A, Liby, Karen T
Published in PloS one (27.07.2011)
Published in PloS one (27.07.2011)
Get full text
Journal Article
New Synthetic Triterpenoids: Potent Agents for Prevention and Treatment of Tissue Injury Caused by Inflammatory and Oxidative Stress
Sporn, Michael B, Liby, Karen T, Yore, Mark M, Fu, Liangfeng, Lopchuk, Justin M, Gribble, Gordon W
Published in Journal of natural products (Washington, D.C.) (25.03.2011)
Published in Journal of natural products (Washington, D.C.) (25.03.2011)
Get full text
Journal Article
Neuroprotective effect of Nrf2/ARE activators, CDDO ethylamide and CDDO trifluoroethylamide, in a mouse model of amyotrophic lateral sclerosis
Neymotin, Arie, Calingasan, Noel Y., Wille, Elizabeth, Naseri, Nima, Petri, Susanne, Damiano, Maria, Liby, Karen T., Risingsong, Renee, Sporn, Michael, Beal, M. Flint, Kiaei, Mahmoud
Published in Free radical biology & medicine (01.07.2011)
Published in Free radical biology & medicine (01.07.2011)
Get full text
Journal Article
Neuroprotective effects of the triterpenoid, CDDO methyl amide, a potent inducer of Nrf2-mediated transcription
Yang, Lichuan, Calingasan, Noel Y, Thomas, Bobby, Chaturvedi, Rajnish K, Kiaei, Mahmoud, Wille, Elizabeth J, Liby, Karen T, Williams, Charlotte, Royce, Darlene, Risingsong, Renee, Musiek, Eric S, Morrow, Jason D, Sporn, Michael, Beal, M Flint
Published in PloS one (01.06.2009)
Published in PloS one (01.06.2009)
Get full text
Journal Article
A nano-liposome formulation of the PARP inhibitor Talazoparib enhances treatment efficacy and modulates immune cell populations in mammary tumors of BRCA-deficient mice
Zhang, Di, Baldwin, Paige, Leal, Ana S, Carapellucci, Sarah, Sridhar, Srinivas, Liby, Karen T
Published in Theranostics (01.01.2019)
Published in Theranostics (01.01.2019)
Get full text
Journal Article
Role of Nrf2 in prevention of high-fat diet-induced obesity by synthetic triterpenoid CDDO-Imidazolide
Shin, Soona, Wakabayashi, Junko, Yates, Melinda S., Wakabayashi, Nobunao, Dolan, Patrick M., Aja, Susan, Liby, Karen T., Sporn, Michael B., Yamamoto, Masayuki, Kensler, Thomas W.
Published in European journal of pharmacology (12.10.2009)
Published in European journal of pharmacology (12.10.2009)
Get full text
Journal Article
CDDO-Me Redirects Activation of Breast Tumor Associated Macrophages
Ball, Michael S, Shipman, Emilie P, Kim, Hyunjung, Liby, Karen T, Pioli, Patricia A
Published in PloS one (26.02.2016)
Published in PloS one (26.02.2016)
Get full text
Journal Article
Dimethyl fumarate and the oleanane triterpenoids, CDDO-imidazolide and CDDO-methyl ester, both activate the Nrf2 pathway but have opposite effects in the A/J model of lung carcinogenesis
To, Ciric, Ringelberg, Carol S, Royce, Darlene B, Williams, Charlotte R, Risingsong, Renee, Sporn, Michael B, Liby, Karen T
Published in Carcinogenesis (New York) (01.07.2015)
Published in Carcinogenesis (New York) (01.07.2015)
Get full text
Journal Article
Sustained, local delivery of the PARP inhibitor talazoparib prevents the development of mammary gland hyperplasia in Brca1-deficient mice
Zhang, Di, Singh, Bijay, Moerland, Jessica, Mitchell, Owen, Lockwood, Lizbeth, Carapellucci, Sarah, Sridhar, Srinivas, Liby, Karen T
Published in Scientific reports (13.01.2021)
Published in Scientific reports (13.01.2021)
Get full text
Journal Article
Targeting Nrf2 with the Triterpenoid CDDO-Imidazolide Attenuates Cigarette Smoke-Induced Emphysema and Cardiac Dysfunction in Mice
Sussan, Thomas E., Rangasamy, Tirumalai, Blake, David J., Malhotra, Deepti, El-Haddad, Hazim, Bedja, Djahida, Yates, Melinda S., Kombairaju, Ponvijay, Yamamoto, Masayuki, Liby, Karen T., Sporn, Michael B., Gabrielson, Kathleen L., Champion, Hunter C., Tuder, Rubin M., Kensler, Thomas W., Biswal, Shyam, Wogan, Gerald N.
Published in Proceedings of the National Academy of Sciences - PNAS (06.01.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (06.01.2009)
Get full text
Journal Article