Subaxial lordosis loss and influence factors after posterior atlantoaxial fusion
Liu, Shaoqiang, Liu, Boling, Liang, Guiqing, Chen, Qiyong, Wang, Huafeng, Lin, Yuhan
Published in Journal of orthopaedic surgery and research (28.03.2022)
Published in Journal of orthopaedic surgery and research (28.03.2022)
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Defective Autophagy and mTORC1 Signaling in Myotubularin Null Mice
Fetalvero, Kristina M., Yu, Yenyen, Goetschkes, Margaret, Liang, Guiqing, Valdez, Reginald A., Gould, Ty, Triantafellow, Ellen, Bergling, Sebastian, Loureiro, Joseph, Eash, John, Lin, Victor, Porter, Jeffrey A., Finan, Peter M., Walsh, Kenneth, Yang, Yi, Mao, Xiaohong, Murphy, Leon O.
Published in Molecular and Cellular Biology (01.01.2013)
Published in Molecular and Cellular Biology (01.01.2013)
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Indole- and indolizine-glyoxylamides displaying cytotoxicity against multidrug resistant cancer cell lines
James, David A., Koya, Keizo, Li, Hao, Liang, Guiqing, Xia, Zhiqiang, Ying, Weiwen, Wu, Yaming, Sun, Lijun
Published in Bioorganic & medicinal chemistry (15.03.2008)
Published in Bioorganic & medicinal chemistry (15.03.2008)
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Structure–Activity Relationships, Pharmacokinetics, and in Vivo Activity of CYP11B2 and CYP11B1 Inhibitors
Papillon, Julien P. N, Adams, Christopher M, Hu, Qi-Ying, Lou, Changgang, Singh, Alok K, Zhang, Chun, Carvalho, Jose, Rajan, Srinivan, Amaral, Adam, Beil, Michael E, Fu, Fumin, Gangl, Eric, Hu, Chii-Whei, Jeng, Arco Y, LaSala, Daniel, Liang, Guiqing, Logman, Michael, Maniara, Wieslawa M, Rigel, Dean F, Smith, Sherri A, Ksander, Gary M
Published in Journal of medicinal chemistry (11.06.2015)
Published in Journal of medicinal chemistry (11.06.2015)
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Journal Article
Aldosterone synthase inhibition: cardiorenal protection in animal disease models and translation of hormonal effects to human subjects
Ménard, Joël, Rigel, Dean F, Watson, Catherine, Jeng, Arco Y, Fu, Fumin, Beil, Michael, Liu, Jing, Chen, Wei, Hu, Chii-Whei, Leung-Chu, Jennifer, LaSala, Daniel, Liang, Guiqing, Rebello, Sam, Zhang, Yiming, Dole, William P
Published in Journal of translational medicine (10.12.2014)
Published in Journal of translational medicine (10.12.2014)
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Seizure reduction in TSC2-mutant mouse model by an mTOR catalytic inhibitor
Dhamne, Sameer C, Modi, Meera E, Gray, Audrey, Bonazzi, Simone, Craig, Lucas, Bainbridge, Elizabeth, Lalani, Lahin, Super, Chloe E, Schaeffer, Samantha, Capre, Ketthsy, Lubicka, Danuta, Liang, Guiqing, Burdette, Doug, McTighe, Stephanie M, Gurnani, Sarika, Vermudez, Sheryl Anne D, Curtis, Daniel, Wilson, Christopher J, Hameed, Mustafa Q, D'Amore, Angelica, Rotenberg, Alexander, Sahin, Mustafa
Published in Annals of clinical and translational neurology (01.10.2023)
Published in Annals of clinical and translational neurology (01.10.2023)
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Evaluation of Pharmaceutical Excipients as Cosolvents in 4-Methyl Umbelliferone Glucuronidation in Human Liver Microsomes: Applications for Compounds with Low Solubility
Argikar, Upendra A., Liang, Guiqing, Bushee, Jennifer L., Hosagrahara, Vinayak P., Lee, Wendy
Published in Drug metabolism and pharmacokinetics (01.01.2011)
Published in Drug metabolism and pharmacokinetics (01.01.2011)
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Journal Article
The discovery of potent inhibitors of aldosterone synthase that exhibit selectivity over 11-β-hydroxylase
Adams, Christopher M., Hu, Chii-Whei, Jeng, Arco Y., Karki, Rajeshri, Ksander, Gary, LaSala, Dan, Leung-Chu, Jennifer, Liang, Guiqing, Liu, Qian, Meredith, Erik, Rao, Chang, Rigel, Dean F., Shi, Jie, Smith, Sherri, Springer, Clayton, Zhang, Chun
Published in Bioorganic & medicinal chemistry letters (01.08.2010)
Published in Bioorganic & medicinal chemistry letters (01.08.2010)
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Thoracic degenerative spondylolisthesis-associated myelopathy: A case report
Wang, Huafeng, Lin, Fengfei, Liang, Guiqing, Liu, Boling, Lin, Yuhan
Published in Medicine (Baltimore) (28.05.2021)
Published in Medicine (Baltimore) (28.05.2021)
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Journal Article
Utility of Chimeric Mice with Humanized Livers for Predicting Hepatic Organic Anion - Transporting Polypeptide 1B (OATP1B) - Mediated Clinical Drug-Drug Interactions
Feng, Bo, Liang, Guiqing, Zetterberg, Craig, Li, Shaolan, Huang, Hui, Williams, John, Gao, Hong, Morikawa, Yoshio, Kumar, Sanjeev
Published in Drug metabolism and disposition (05.08.2024)
Published in Drug metabolism and disposition (05.08.2024)
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The activities of drug inactive ingredients on biological targets
Pottel, Joshua, Armstrong, Duncan, Zou, Ling, Fekete, Alexander, Huang, Xi-Ping, Torosyan, Hayarpi, Bednarczyk, Dallas, Whitebread, Steven, Bhhatarai, Barun, Liang, Guiqing, Jin, Hong, Ghaemi, S Nassir, Slocum, Samuel, Lukacs, Katalin V, Irwin, John J, Berg, Ellen L, Giacomini, Kathleen M, Roth, Bryan L, Shoichet, Brian K, Urban, Laszlo
Published in Science (American Association for the Advancement of Science) (24.07.2020)
Published in Science (American Association for the Advancement of Science) (24.07.2020)
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Journal Article
Evaluation of Pharmaceutical Excipients as Cosolvents in 4-Methyl Umbelliferone Glucuronidation in Human Liver Microsomes: Applications for Compounds with Low Solubility
Upendra A.ARGIKAR, Guiqing LIANG, Jennifer L.BUSHEE, Vinayak P.HOSAGRAHARA, Wendy LEE
Published in DRUG METABOLISM AND PHARMACOKINETICS (2011)
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Published in DRUG METABOLISM AND PHARMACOKINETICS (2011)
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Building Confidence in Physiologically Based Pharmacokinetic Modeling of CYP3A Induction Mediated by Rifampin: An Industry Perspective
Reddy, Micaela B, Cabalu, Tamara D, de Zwart, Loeckie, Ramsden, Diane, Dowty, Martin E, Taskar, Kunal S, Badée, Justine, Bolleddula, Jayaprakasam, Boulu, Laurent, Fu, Qiang, Kotsuma, Masakatsu, Leblanc, Alix F, Lewis, Gareth, Liang, Guiqing, Parrott, Neil, Pilla Reddy, Venkatesh, Prakash, Chandra, Shah, Kushal, Umehara, Kenichi, Mukherjee, Dwaipayan, Rehmel, Jessica, Hariparsad, Niresh
Published in Clinical pharmacology and therapeutics (18.10.2024)
Published in Clinical pharmacology and therapeutics (18.10.2024)
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Discovery of Darovasertib (NVP-LXS196), a Pan-PKC Inhibitor for the Treatment of Metastatic Uveal Melanoma
Visser, Michael, Papillon, Julien P. N., Luzzio, Michael, LaMarche, Matthew J., Fan, Jianmei, Michael, Walter, Wang, David, Zhang, Alan, Straub, Christopher, Mathieu, Simon, Kato, Mitsunori, Palermo, Mark, Chen, Christine, Ramsey, Timothy, Joud, Carol, Barrett, Rosemary, Vattay, Anthony, Guo, Ribo, Bric, Anka, Chung, Franklin, Liang, Guiqing, Romanowski, Michael J., Lam, Joni, Thohan, Sanjeev, Atassi, Faraj, Wylie, Andrew, Cooke, Vesselina G.
Published in Journal of medicinal chemistry (25.01.2024)
Published in Journal of medicinal chemistry (25.01.2024)
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Discovery and Evaluation of Clinical Candidate IDH305, a Brain Penetrant Mutant IDH1 Inhibitor
Cho, Young Shin, Levell, Julian R, Liu, Gang, Caferro, Thomas, Sutton, James, Shafer, Cynthia M, Costales, Abran, Manning, James R, Zhao, Qian, Sendzik, Martin, Shultz, Michael, Chenail, Gregg, Dooley, Julia, Villalba, Brian, Farsidjani, Ali, Chen, Jinyun, Kulathila, Raviraj, Xie, Xiaoling, Dodd, Stephanie, Gould, Ty, Liang, Guiqing, Heimbach, Tycho, Slocum, Kelly, Firestone, Brant, Pu, Minying, Pagliarini, Raymond, Growney, Joseph D
Published in ACS medicinal chemistry letters (12.10.2017)
Published in ACS medicinal chemistry letters (12.10.2017)
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Discovery of a Brain-Penetrant ATP-Competitive Inhibitor of the Mechanistic Target of Rapamycin (mTOR) for CNS Disorders
Bonazzi, Simone, Goold, Carleton P, Gray, Audrey, Thomsen, Noel M, Nunez, Jill, Karki, Rajeshri G, Gorde, Aakruti, Biag, Jonathan D, Malik, Hasnain A, Sun, Yingchuan, Liang, Guiqing, Lubicka, Danuta, Salas, Sarah, Labbe-Giguere, Nancy, Keaney, Erin P, McTighe, Stephanie, Liu, Shanming, Deng, Lin, Piizzi, Grazia, Lombardo, Franco, Burdette, Doug, Dodart, Jean-Cosme, Wilson, Christopher J, Peukert, Stefan, Curtis, Daniel, Hamann, Lawrence G, Murphy, Leon O
Published in Journal of medicinal chemistry (13.02.2020)
Published in Journal of medicinal chemistry (13.02.2020)
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