Assessment of serum bile acid profiles as biomarkers of liver injury and liver disease in humans
Luo, Lina, Aubrecht, Jiri, Li, Dingzhou, Warner, Roscoe L, Johnson, Kent J, Kenny, Julia, Colangelo, Jennifer L
Published in PloS one (07.03.2018)
Published in PloS one (07.03.2018)
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Cross-site and cross-platform variability of automated patch clamp assessments of drug effects on human cardiac currents in recombinant cells
Kramer, James, Himmel, Herbert M., Lindqvist, Anders, Stoelzle-Feix, Sonja, Chaudhary, Khuram W., Li, Dingzhou, Bohme, Georg Andrees, Bridgland-Taylor, Matthew, Hebeisen, Simon, Fan, Jingsong, Renganathan, Muthukrishnan, Imredy, John, Humphries, Edward S. A., Brinkwirth, Nina, Strassmaier, Tim, Ohtsuki, Atsushi, Danker, Timm, Vanoye, Carlos, Polonchuk, Liudmila, Fermini, Bernard, Pierson, Jennifer Beck, Gintant, Gary
Published in Scientific reports (27.03.2020)
Published in Scientific reports (27.03.2020)
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Publisher Correction: Cross-site and cross-platform variability of automated patch clamp assessments of drug effects on human cardiac currents in recombinant cells
Kramer, James, Himmel, Herbert M., Lindqvist, Anders, Stoelzle-Feix, Sonja, Chaudhary, Khuram W., Li, Dingzhou, Bohme, Georg Andrees, Bridgland-Taylor, Matthew, Hebeisen, Simon, Fan, Jingsong, Renganathan, Muthukrishnan, Imredy, John, Humphries, Edward S. A., Brinkwirth, Nina, Strassmaier, Tim, Ohtsuki, Atsushi, Danker, Timm, Vanoye, Carlos, Polonchuk, Liudmila, Fermini, Bernard, Pierson, Jennifer Beck, Gintant, Gary
Published in Scientific reports (14.07.2020)
Published in Scientific reports (14.07.2020)
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Journal Article
Cross-company evaluation of the human lymphocyte activation assay
Collinge, Mark, Schneider, Patricia, Li, Dingzhou, Parish, Stanley, Dumont, Carolyne, Freebern, Wendy, Ghanime, Joseph, Guimont-Derochers, Fanny, Langenkamp, Anja, Lebron, Jose, Li, Nianyu, Marban, Celine, Plitnick, Lisa, Wheeler, Jennifer
Published in Journal of immunotoxicology (01.01.2020)
Published in Journal of immunotoxicology (01.01.2020)
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Study design for development of novel safety biomarkers of drug-induced liver injury by the translational safety biomarker pipeline (TransBioLine) consortium: a study protocol for a nested case–control study
Grove, Jane I., Stephens, Camilla, Lucena, M. Isabel, Andrade, Raúl J., Weber, Sabine, Gerbes, Alexander, Bjornsson, Einar S., Stirnimann, Guido, Daly, Ann K., Hackl, Matthias, Khamina-Kotisch, Kseniya, Marin, Jose J. G., Monte, Maria J., Paciga, Sara A., Lingaya, Melanie, Forootan, Shiva S., Goldring, Christopher E. P., Poetz, Oliver, Lombaard, Rudolf, Stege, Alexandra, Bjorrnsson, Helgi K., Robles-Diaz, Mercedes, Li, Dingzhou, Tran, Thi Dong Binh, Ramaiah, Shashi K., Samodelov, Sophia L., Kullak-Ublick, Gerd A., Aithal, Guruprasad P.
Published in Diagnostic and prognostic research (12.09.2023)
Published in Diagnostic and prognostic research (12.09.2023)
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Development and validation of an in vitro micronucleus assay platform in TK6 cells
Sobol, Zhanna, Homiski, Michael L., Dickinson, Donna A., Spellman, Richard A., Li, Dingzhou, Scott, Andrew, Cheung, Jennifer R., Coffing, Stephanie L., Munzner, Jennifer B., Sanok, Kelley E., Gunther, William C., Dobo, Krista L., Schuler, Maik
Published in Mutation research (04.07.2012)
Published in Mutation research (04.07.2012)
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Journal Article
Statistical applications of virtual control groups to nonrodent animal toxicity studies: An initial evaluation
Li, Dingzhou, Garren, Jeonifer, Mangipudy, Raja, Martin, Matthew, Tomlinson, Lindsay, Vansell, Nichole R.
Published in Regulatory toxicology and pharmacology (01.12.2024)
Published in Regulatory toxicology and pharmacology (01.12.2024)
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Non-linear, non-invasive method for seizure anticipation in focal epilepsy
Li, Dingzhou, Zhou, Weiping, Drury, Ivo, Savit, Robert
Published in Mathematical biosciences (01.11.2003)
Published in Mathematical biosciences (01.11.2003)
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Characterization of a high throughput human stem cell cardiomyocyte assay to predict drug-induced changes in clinical electrocardiogram parameters
Kilfoil, Peter, Feng, Shuyun Lily, Bassyouni, Asser, Lee, Tiffany, Leishman, Derek, Li, Dingzhou, MacEwan, David J., Sharma, Parveen, Watt, Eric D., Jenkinson, Stephen
Published in European journal of pharmacology (05.12.2021)
Published in European journal of pharmacology (05.12.2021)
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Journal Article
Characterizing Intra-Tumor and Inter-Tumor Variability of Immune Cell Infiltrates in Murine Syngeneic Tumors
Mojtahedzadeh, Sepideh, Opsahl, Alan, Aguilar, Joan-Kristel, Li, Dingzhou, Streiner, Nicole, Wang, Jinwei, Trajkovic, Dusko, Boucher, Germaine, Coskran, Timothy, O'Neil, Shawn P., Ram, Sripad
Published in The American journal of pathology (01.12.2021)
Published in The American journal of pathology (01.12.2021)
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Points to consider regarding the use and implementation of virtual controls in nonclinical general toxicology studies
Palazzi, Xavier, Anger, Lennart T., Boulineau, Theresa, Grevot, Armelle, Guffroy, Magali, Henson, Kristin, Hoepp, Natalie, Jacobsen, Matt, Kale, Vijay P., Kreeger, John, Lane, Joan H., Li, Dingzhou, Muster, Wolfgang, Paisley, Brianna, Ramaiah, Lila, Robertson, Nicola, Shultz, Valerie, Steger Hartmann, Thomas, Westhouse, Richard
Published in Regulatory toxicology and pharmacology (01.06.2024)
Published in Regulatory toxicology and pharmacology (01.06.2024)
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The partnership between statisticians and the Institutional Animal Care and Use Committee (IACUC)
Potter, David, Bradstreet, Thomas, Sargsyan, Davit, Tan, Xiao, Bonato, Vinicius, Li, Dingzhou, Liang, John, Libiger, Ondrej, Sendecki, Jocelyn, Stansfield, John, Tatikola, Kanaka, Xu, Jialin, Campbell, Brandy
Published in Pharmaceutical statistics : the journal of the pharmaceutical industry (11.06.2024)
Published in Pharmaceutical statistics : the journal of the pharmaceutical industry (11.06.2024)
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Assessing the quality and making appropriate use of historical negative control data: A report of the International Workshop on Genotoxicity Testing (IWGT)
Dertinger, Stephen D, Li, Dingzhou, Beevers, Carol, Douglas, George R, Heflich, Robert H, Lovell, David P, Roberts, Daniel J, Smith, Robert, Uno, Yoshifumi, Williams, Andrew, Witt, Kristine L, Zeller, Andreas, Zhou, Changhui
Published in Environmental and molecular mutagenesis (25.04.2023)
Published in Environmental and molecular mutagenesis (25.04.2023)
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Best practice considerations for nonclinical in vivo cardiovascular telemetry studies in non-rodent species: Delivering high quality QTc data to support ICH E14/S7B Q&As
Rossman, Eric I., Wisialowski, Todd A., Vargas, Hugo M., Valentin, Jean-Pierre, Rolf, Michael G., Roche, Brian M., Riley, Steve, Pugsley, Michael K., Nichols, Jill, Li, Dingzhou, Leishman, Derek J., Kleiman, Robert B., Greiter-Wilke, Andrea, Gintant, Gary A., Engwall, Michael J., Delaunois, Annie, Authier, Simon
Published in Journal of pharmacological and toxicological methods (01.09.2023)
Published in Journal of pharmacological and toxicological methods (01.09.2023)
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Quantitative association analyses of CNS safety pharmacology parameters to clinical observations in toxicology studies
DaSilva, Jamie K., Cobbina, Enoch, Tyszkiewicz, Cheryl, Li, Dingzhou, Goody, Susan
Published in Journal of pharmacological and toxicological methods (01.09.2019)
Published in Journal of pharmacological and toxicological methods (01.09.2019)
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Assessment of corrected JT-peak (JTpc) and Tpeak-to-Tend (TpTec) as proarrhythmia biomarkers in non-human primates: Outcome from a HESI consortium
Boulay, Emmanuel, Authier, Simon, Bartko, Theresa, Greiter-Wilke, Andrea, Leishman, Derek, Li, Dingzhou, Nichols, Jill V., Pierson, Jennifer, Rossman, Eric I., Valentin, Jean-Pierre, Vicente, Jose, Walisser, Jacqueline, Troncy, Eric, Wisialowski, Todd A.
Published in Journal of pharmacological and toxicological methods (01.09.2024)
Published in Journal of pharmacological and toxicological methods (01.09.2024)
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