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The role of clinical pharmacology across novel treatment modalities
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Mycobacterium tuberculosis Upregulates TNF-α Expression via TLR2/ERK Signaling and Induces MMP-1 and MMP-9 Production in Human Pleural Mesothelial Cells
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Assessment of CYP3A‐mediated drug interaction via cytokine (IL‐6) elevation for mosunetuzumab using physiologically‐based pharmacokinetic modeling
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Systems‐based digital twins to help characterize clinical dose–response and propose predictive biomarkers in a Phase I study of bispecific antibody, mosunetuzumab, in NHL
Susilo, Monica E., Li, Chi‐Chung, Gadkar, Kapil, Hernandez, Genevive, Huw, Ling‐Yuh, Jin, Jin Y., Yin, Shen, Wei, Michael C., Ramanujan, Saroja, Hosseini, Iraj
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Population PK Analyses of Ubrogepant (MK-1602), a CGRP Receptor Antagonist: Enriching In-Clinic Plasma PK Sampling With Outpatient Dried Blood Spot Sampling
Li, Chi-Chung, Dockendorf, Marissa, Kowalski, Ken, Yang, Bei, Xu, Yang, Xie, Iris, Kleijn, Huub Jan, Bosch, Rolien, Jones, Christopher, Thornton, Bob, Marcantonio, Eugene E, Voss, Tiffini, Bateman, Kevin P, Kothare, Prajakti A
Published in Journal of clinical pharmacology (01.03.2018)
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Toll-like Receptor 2 Mediates VEGF Overexpression and Mesothelial Hyperpermeability in Tuberculous Pleural Effusion
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Considerations for Industry—Preparing for the FDA Model‐Informed Drug Development (MIDD) Paired Meeting Program
Galluppi, Gerald R., Ahamadi, Malidi, Bhattacharya, Souvik, Budha, Nageshwar, Gheyas, Ferdous, Li, Chi‐Chung, Chen, Yuan, Dosne, Anne‐Gaëlle, Kristensen, Niels Rode, Magee, Mindy, Samtani, Mahesh N., Sinha, Vikram, Taskar, Kunal, Upreti, Vijay V., Yang, Jianning, Cook, Jack
Published in Clinical pharmacology and therapeutics (01.08.2024)
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A PK/PD Analysis of Circulating Biomarkers and Their Relationship to Tumor Response in Atezolizumab‐Treated non‐small Cell Lung Cancer Patients
Netterberg, Ida, Li, Chi‐Chung, Molinero, Luciana, Budha, Nageshwar, Sukumaran, Siddharth, Stroh, Mark, Jonsson, E. Niclas, Friberg, Lena E.
Published in Clinical pharmacology and therapeutics (01.02.2019)
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Mitigating the risk of cytokine release syndrome in a Phase I trial of CD20/CD3 bispecific antibody mosunetuzumab in NHL: impact of translational system modeling
Hosseini, Iraj, Gadkar, Kapil, Stefanich, Eric, Li, Chi-Chung, Sun, Liping L., Chu, Yu-Waye, Ramanujan, Saroja
Published in NPJ systems biology and applications (28.08.2020)
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Glabridin, a Bioactive Flavonoid from Licorice, Effectively Inhibits Platelet Activation in Humans and Mice
Chung, Chi-Li, Chen, Jui-Hsuan, Huang, Wei-Chieh, Sheu, Joen-Rong, Hsia, Chih-Wei, Jayakumar, Thanasekaran, Hsia, Chih-Hsuan, Chiou, Kuan-Rau, Hou, Shaw-Min
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Industrial Perspective on the Benefits Realized From the FDA’s Model‐Informed Drug Development Paired Meeting Pilot Program
Galluppi, Gerald R., Brar, Satjit, Caro, Luzelena, Chen, Yuan, Frey, Nicolas, Grimm, Hans Peter, Rudd, Deanne Jackson, Li, Chi‐Chung, Magee, Mindy, Mukherjee, Arnab, Nagao, Lee, Purohit, Vivek S., Roy, Amit, Salem, Ahmed Hamed, Sinha, Vikram, Suleiman, Ahmed A., Taskar, Kunal S., Upreti, Vijay V., Weber, Benjamin, Cook, Jack
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Decreased Human Platelet Activation and Mouse Pulmonary Thrombosis by Rutaecarpine and Comparison of the Relative Effectiveness with BAY11-7082: Crucial Signals of p38-NF-κB
Huang, Wei-Chieh, Hou, Shaw-Min, Wu, Ming-Ping, Hsia, Chih-Wei, Jayakumar, Thanasekaran, Hsia, Chih-Hsuan, Bhavan, Periyakali Saravana, Chung, Chi-Li, Sheu, Joen-Rong
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Artificial intelligence classification model for macular degeneration images: a robust optimization framework for residual neural networks
Ho, Wen-Hsien, Huang, Tian-Hsiang, Yang, Po-Yuan, Chou, Jyh-Horng, Huang, Hong-Siang, Chi, Li-Chung, Chou, Fu-I, Tsai, Jinn-Tsong
Published in BMC bioinformatics (08.11.2021)
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A novel 2‐aminobenzimidazole‐based compound Jzu 17 exhibits anti‐angiogenesis effects by targeting VEGFR‐2 signalling
Lien, Jin‐Cherng, Chung, Chi‐Li, Huang, Tur‐Fu, Chang, Tsung‐Chia, Chen, Kuan‐Chung, Gao, Ging‐Yan, Hsu, Ming‐Jen, Huang, Shiu‐Wen
Published in British journal of pharmacology (01.10.2019)
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Regulation of Human Platelet Activation and Prevention of Arterial Thrombosis in Mice by Auraptene through Inhibition of NF-κB Pathway
Hsia, Chih-Wei, Wu, Ming-Ping, Shen, Ming-Yi, Hsia, Chih-Hsuan, Chung, Chi-Li, Sheu, Joen-Rong
Published in International journal of molecular sciences (07.07.2020)
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Diabetes risks and outcomes in chronic obstructive pulmonary disease patients: Two nationwide population-based retrospective cohort studies
Lin, Chao-Shun, Liu, Chih-Chung, Yeh, Chun-Chieh, Chang, Yi-Cheng, Chung, Chi-Li, Lane, Hsin-Long, Shih, Chun-Chuan, Chen, Ta-Liang, Liao, Chien-Chang
Published in PloS one (16.08.2017)
Published in PloS one (16.08.2017)
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Suppression of reactive oxygen species‐mediated ERK and JNK activation sensitizes dihydromyricetin‐induced mitochondrial apoptosis in human non‐small cell lung cancer
Kao, Shang‐Jyh, Lee, Wei‐Jiunn, Chang, Jer‐Hwa, Chow, Jyh‐Ming, Chung, Chi‐Li, Hung, Wen‐Yueh, Chien, Ming‐Hsien
Published in Environmental toxicology (01.04.2017)
Published in Environmental toxicology (01.04.2017)
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