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Alzheimer's Targeted Treatments: Focus on Amyloid and Inflammation
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The Ubiquitin Ligase Phr1 Regulates Axon Outgrowth through Modulation of Microtubule Dynamics
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Published in Cell (02.09.2021)
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Siu, Michael, Sengupta Ghosh, Arundhati, Lewcock, Joseph W
Published in Journal of medicinal chemistry (27.09.2018)
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Selective Inhibitors of Dual Leucine Zipper Kinase (DLK, MAP3K12) with Activity in a Model of Alzheimer’s Disease
Patel, Snahel, Meilandt, William J, Erickson, Rebecca I, Chen, Jinhua, Deshmukh, Gauri, Estrada, Anthony A, Fuji, Reina N, Gibbons, Paul, Gustafson, Amy, Harris, Seth F, Imperio, Jose, Liu, Wendy, Liu, Xingrong, Liu, Yichin, Lyssikatos, Joseph P, Ma, Changyou, Yin, Jianping, Lewcock, Joseph W, Siu, Michael
Published in Journal of medicinal chemistry (12.10.2017)
Published in Journal of medicinal chemistry (12.10.2017)
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Published in Cell (07.01.2011)
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Published in Nature communications (19.08.2023)
Published in Nature communications (19.08.2023)
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Scaffold-Hopping and Structure-Based Discovery of Potent, Selective, And Brain Penetrant N‑(1H‑Pyrazol-3-yl)pyridin-2-amine Inhibitors of Dual Leucine Zipper Kinase (DLK, MAP3K12)
Patel, Snahel, Harris, Seth F, Gibbons, Paul, Deshmukh, Gauri, Gustafson, Amy, Kellar, Terry, Lin, Han, Liu, Xingrong, Liu, Yanzhou, Liu, Yichin, Ma, Changyou, Scearce-Levie, Kimberly, Ghosh, Arundhati Sengupta, Shin, Young G, Solanoy, Hilda, Wang, Jian, Wang, Bei, Yin, Jianping, Siu, Michael, Lewcock, Joseph W
Published in Journal of medicinal chemistry (22.10.2015)
Published in Journal of medicinal chemistry (22.10.2015)
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