CD95 Structure, Aggregation and Cell Signaling
Levoin, Nicolas, Jean, Mickael, Legembre, Patrick
Published in Frontiers in cell and developmental biology (05.05.2020)
Published in Frontiers in cell and developmental biology (05.05.2020)
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Journal Article
MMP7 cleavage of amino-terminal CD95 death receptor switches signaling toward non-apoptotic pathways
Kenji, Shoji F., Kurma, Keerthi, Collet, Brigitte, Oblet, Christelle, Debure, Laure, Di Primo, Carmelo, Minder, Laëtitia, Vérité, Franck, Danger, Yannic, Jean, Mickael, Penna, Aubin, Levoin, Nicolas, Legembre, Patrick
Published in Cell death & disease (23.10.2022)
Published in Cell death & disease (23.10.2022)
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Journal Article
Structure Activity Relationship Studies around DB18, a Potent and Selective Inhibitor of CLK Kinases
Brahmaiah, Dabbugoddu, Bhavani, Anagani Kanaka Durga, Aparna, Pasula, Kumar, Nangunoori Sampath, Solhi, Hélène, Le Guevel, Rémy, Baratte, Blandine, Robert, Thomas, Ruchaud, Sandrine, Bach, Stéphane, Jadav, Surender Singh, Reddy, Chada Raji, Mosset, Paul, Gouault, Nicolas, Levoin, Nicolas, Grée, René
Published in Molecules (Basel, Switzerland) (20.09.2022)
Published in Molecules (Basel, Switzerland) (20.09.2022)
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Journal Article
Molecular Tweezers: Synthesis and Formation of Host-Guest Complexes
Legouin, Béatrice, Gayral, Maud, Uriac, Philippe, Cupif, Jean-François, Levoin, Nicolas, Toupet, Loic, van de Weghe, Pierre
Published in European Journal of Organic Chemistry (01.10.2010)
Published in European Journal of Organic Chemistry (01.10.2010)
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Book Review
Journal Article
Refined Docking as a Valuable Tool for Lead Optimization: Application to Histamine H3 Receptor Antagonists
Levoin, Nicolas, Calmels, Thierry, Poupardin-Olivier, Olivia, Labeeuw, Olivier, Danvy, Denis, Robert, Philippe, Berrebi-Bertrand, Isabelle, Ganellin, C. Robin, Schunack, Walter, Stark, Holger, Capet, Marc
Published in Archiv der Pharmazie (Weinheim) (01.10.2008)
Published in Archiv der Pharmazie (Weinheim) (01.10.2008)
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Journal Article
Preliminary Studies on the Activity of Mixed Polyphenol-Heterocyclic Systems Against B16-F10 Melanoma Cancer Cells
Duy Vo, Duc, Rouaud, Isabelle, Le Devehat, Francoise, Gautier, Fabien, Barillé-Nion, Sophie, Juin, Philippe, Levoin, Nicolas, Boustie, Joël, Grée, René
Published in Medicinal chemistry (Shp-sariqah, United Arab Emirates) (01.01.2016)
Published in Medicinal chemistry (Shp-sariqah, United Arab Emirates) (01.01.2016)
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Journal Article
CD95L concatemers highlight different stoichiometries of CD95‐mediated apoptotic and non‐apoptotic pathways
Lebrault, Eden, Oblet, Christelle, Kurma, Keerthi, Levoin, Nicolas, Jeannet, Robin, Jean, Mickael, Vacher, Pierre, Legembre, Patrick
Published in European journal of immunology (14.10.2023)
Published in European journal of immunology (14.10.2023)
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Journal Article
CD95L concatemers highlight different stoichiometries of CD95‐mediated apoptotic and nonapoptotic pathways
Lebrault, Eden, Oblet, Christelle, Kurma, Keerthi, Levoin, Nicolas, Jeannet, Robin, Jean, Mickael, Vacher, Pierre, Legembre, Patrick
Published in European journal of immunology (01.01.2024)
Published in European journal of immunology (01.01.2024)
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Journal Article
Discovery of potent dual ligands for dopamine D4 and σ1 receptors
Levoin, Nicolas, Murthy, Appala Venkata Ramana, Narendar, Vennu, Kumar, Nangunoori Sampath, Aparna, Pasula, Bhavani, Anagani Kanaka Durga, Reddy, Chada Raji, Mosset, Paul, Grée, René
Published in Bioorganic & medicinal chemistry (01.09.2022)
Published in Bioorganic & medicinal chemistry (01.09.2022)
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Journal Article
The Donor Substrate Specificity of the Human β1,3-Glucuronosyltransferase I toward UDP-Glucuronic Acid Is Determined by Two Crucial Histidine and Arginine Residues
Ouzzine, Mohamed, Gulberti, Sandrine, Levoin, Nicolas, Netter, Patrick, Magdalou, Jacques, Fournel-Gigleux, Sylvie
Published in The Journal of biological chemistry (01.07.2002)
Published in The Journal of biological chemistry (01.07.2002)
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Journal Article
CD95-Mediated Calcium Signaling Promotes T Helper 17 Trafficking to Inflamed Organs in Lupus-Prone Mice
Poissonnier, Amanda, Sanséau, Doriane, Le Gallo, Matthieu, Malleter, Marine, Levoin, Nicolas, Viel, Roselyne, Morere, Lucie, Penna, Aubin, Blanco, Patrick, Dupuy, Alain, Poizeau, Florence, Fautrel, Alain, Seneschal, Julien, Jouan, Florence, Ritz, Jerome, Forcade, Edouard, Rioux, Nathalie, Contin-Bordes, Cécile, Ducret, Thomas, Vacher, Anne-Marie, Barrow, Paul A., Flynn, Robin J., Vacher, Pierre, Legembre, Patrick
Published in Immunity (Cambridge, Mass.) (19.07.2016)
Published in Immunity (Cambridge, Mass.) (19.07.2016)
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Journal Article
Probing the side chain tolerance for inhibitors of the CD95/PLC gamma 1 interaction
Ha Thanh Nguyen, Guegan, Jean-Philippe, Best, Daniel, van de Weghe, Pierre, Levoin, Nicolas, Legembre, Patrick, Jean, Mickael
Published in Bioorganic & medicinal chemistry letters (01.11.2019)
Published in Bioorganic & medicinal chemistry letters (01.11.2019)
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Journal Article
Induction of Intracellular Calcium Concentration by Environmental Benzo(a)pyrene Involves a β2-Adrenergic Receptor/Adenylyl Cyclase/Epac-1/Inositol 1,4,5-Trisphosphate Pathway in Endothelial Cells
Mayati, Abdullah, Levoin, Nicolas, Paris, Hervé, N'Diaye, Monique, Courtois, Arnaud, Uriac, Philippe, Lagadic-Gossmann, Dominique, Fardel, Olivier, Le Ferrec, Eric
Published in The Journal of biological chemistry (03.02.2012)
Published in The Journal of biological chemistry (03.02.2012)
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Journal Article
Structure Activity Relationship Studies around IDB18/I, a Potent and Selective Inhibitor of CLK Kinases
Brahmaiah, Dabbugoddu, Bhavani, Anagani Kanaka Durga, Aparna, Pasula, Kumar, Nangunoori Sampath, Solhi, Hélène, Le Guevel, Rémy, Baratte, Blandine, Robert, Thomas, Ruchaud, Sandrine, Bach, Stéphane, Jadav, Surender Singh, Reddy, Chada Raji, Mosset, Paul, Gouault, Nicolas, Levoin, Nicolas, Grée, René
Published in Molecules (Basel, Switzerland) (01.09.2022)
Published in Molecules (Basel, Switzerland) (01.09.2022)
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Journal Article
Discovery of DB18, a potent inhibitor of CLK kinases with a high selectivity against DYRK1A kinase
Brahmaiah, Dabbugoddu, Kanaka Durga Bhavani, Anagani, Aparna, Pasula, Sampath Kumar, Nangunoori, Solhi, Hélène, Le Guevel, Rémy, Baratte, Blandine, Ruchaud, Sandrine, Bach, Stéphane, Singh Jadav, Surender, Raji Reddy, Chada, Roisnel, Thierry, Mosset, Paul, Levoin, Nicolas, Grée, René
Published in Bioorganic & medicinal chemistry (01.02.2021)
Published in Bioorganic & medicinal chemistry (01.02.2021)
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Journal Article
Synthesis and biological evaluation of , a compound originally described as and an inhibitor of the anti-apoptotic protein Mcl-1
Justaud, Frédéric, Paysant, Hippolyte, Weiswald, Louis Bastien, Jebahi, Abdelghani, Jouanne, Marie, Elie, Nicolas, Voisin-Chiret, Anne Sophie, Roisnel, Thierry, Orione, Clément, Levoin, Nicolas, Poulain, Laurent, Grée, René
Published in New journal of chemistry (16.05.2022)
Published in New journal of chemistry (16.05.2022)
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Journal Article
Disrupting the CD95–PLCγ1 interaction prevents Th17-driven inflammation
Poissonnier, Amanda, Guégan, Jean-Philippe, Nguyen, Ha Thanh, Best, Daniel, Levoin, Nicolas, Kozlov, Guennadi, Gehring, Kalle, Pineau, Raphael, Jouan, Florence, Morere, Lucie, Martin, Sophie, Thomas, Mélissa, Lazaro, Estibaliz, Douchet, Isabelle, Ducret, Thomas, van de Weghe, Pierre, Blanco, Patrick, Jean, Mickael, Vacher, Pierre, Legembre, Patrick
Published in Nature chemical biology (01.12.2018)
Published in Nature chemical biology (01.12.2018)
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Journal Article
Synthesis and biological evaluation of FJ-809, a compound originally described as MIM1 and an inhibitor of the anti-apoptotic protein Mcl-1
Justaud, Frédéric, Paysant, Hippolyte, Weiswald, Louis Bastien, Jebahi, Abdelghani, Jouanne, Marie, Elie, Nicolas, Voisin-Chiret, Anne Sophie, Roisnel, Thierry, Orione, Clément, Levoin, Nicolas, Poulain, Laurent, Grée, René
Published in New journal of chemistry (2022)
Published in New journal of chemistry (2022)
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Journal Article