Performance upgrade of a microbial explosives’ sensor strain by screening a high throughput saturation library of a transcriptional regulator
David, Lidor, Shpigel, Etai, Levin, Itay, Moshe, Shaked, Zimmerman, Lior, Dadon-Simanowitz, Shilat, Shemer, Benjamin, Levkovich, Shon A., Larush, Liraz, Magdassi, Shlomo, Belkin, Shimshon
Published in Computational and structural biotechnology journal (01.01.2023)
Published in Computational and structural biotechnology journal (01.01.2023)
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Journal Article
Identification of an unconventional E3 binding surface on the UbcH5 ~ Ub conjugate recognized by a pathogenic bacterial E3 ligase
Levin, Itay, Eakin, Catherine, Blanc, Marie-Pierre, Klevit, Rachel E, Miller, Samuel I, Brzovic, Peter S
Published in Proceedings of the National Academy of Sciences - PNAS (16.02.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (16.02.2010)
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Journal Article
Redirecting an anti-IL-1β antibody to bind a new, unrelated and computationally predicted epitope on hIL-17A
Fischman, Sharon, Levin, Itay, Rondeau, Jean-Michel, Štrajbl, Marek, Lehmann, Sylvie, Huber, Thomas, Nimrod, Guy, Cebe, Régis, Omer, Dotan, Kovarik, Jiri, Bernstein, Shmuel, Sasson, Yehezkel, Demishtein, Alik, Shlamkovich, Tomer, Bluvshtein, Olga, Grossman, Noam, Barak-Fuchs, Reut, Zhenin, Michael, Fastman, Yair, Twito, Shir, Vana, Tal, Zur, Nevet, Ofran, Yanay
Published in Communications biology (29.09.2023)
Published in Communications biology (29.09.2023)
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Journal Article
704 The computationally designed human antibody, AU-007, mediates human immune activation by endogenous IL-2, while uniquely breaking the IL-2 auto-inhibitory loop and preventing Treg expansion
Amit, Inbar, Levin, Itay, Wyant, Timothy, Levitan, Natali, Barak, Reut, Ben-Mayor, May, Bluvshtein, Olga, Grossman, Noam, Sasson, Yehezkel, Nimrod, Guy, Zehnin, Michael, Fischman, Sharon, Štrajbl, Marek, Danielpur, Liron, Knickerbocker, Aron, Vasselli, James, Ofran, Yanay
Published in Journal for immunotherapy of cancer (01.11.2021)
Published in Journal for immunotherapy of cancer (01.11.2021)
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Journal Article
Increased Potency of a Bi-specific TL1A-ADAM17 (TACE) Inhibitor by Cell Surface Targeting
Weizman, Tomer, Levin, Itay, Zaretsky, Marianna, Sagi, Irit, Aharoni, Amir
Published in Frontiers in molecular biosciences (22.08.2017)
Published in Frontiers in molecular biosciences (22.08.2017)
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Journal Article
An alternative pathway for reduced folate biosynthesis in bacteria and halophilic archaea
Levin, Itay, Giladi, Moshe, Altman‐Price, Neta, Ortenberg, Ron, Mevarech, Moshe
Published in Molecular microbiology (01.12.2004)
Published in Molecular microbiology (01.12.2004)
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Journal Article
FolM, A New Chromosomally Encoded Dihydrofolate Reductase in Escherichia coli
Giladi, Moshe, Altman-Price, Neta, Levin, Itay, Levy, Liat, Mevarech, Moshe
Published in Journal of Bacteriology (01.12.2003)
Published in Journal of Bacteriology (01.12.2003)
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Journal Article
Context-dependent design of induced-fit enzymes using deep learning generates well-expressed, thermally stable and active enzymes
Zimmerman, Lior, Alon, Noga, Levin, Itay, Koganitsky, Anna, Shpigel, Nufar, Brestel, Chen, Lapidoth, Gideon D
Published in Proceedings of the National Academy of Sciences - PNAS (12.03.2024)
Published in Proceedings of the National Academy of Sciences - PNAS (12.03.2024)
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Journal Article
Accurate profiling of full-length Fv in highly homologous antibody libraries using UMI tagged short reads
Levin, Itay, Štrajbl, Marek, Fastman, Yair, Baran, Dror, Twito, Shir, Mioduser, Jessica, Keren, Adi, Fischman, Sharon, Zhenin, Michael, Nimrod, Guy, Levitin, Natalie, Mayor, May Ben, Gadrich, Meital, Ofran, Yanay
Published in Nucleic acids research (23.06.2023)
Published in Nucleic acids research (23.06.2023)
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Journal Article
Characterization of BDG8: An antibody-human IL-2 complex that selectively activates the effector arm of the immune system
Wyant, Timothy, Amit, Inbar, Levin, Itay, Levitan, Natali, Grossman, Noam, Bluvshtein, Olga, Barak, Ruet, Nimrod, Guy, Fischman, Sharon, Strajbl, Marek, Sasson, Yehezkel, Zehnin, Michael, Ofran, Yanay
Published in Journal of clinical oncology (20.05.2020)
Published in Journal of clinical oncology (20.05.2020)
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Journal Article
IL-2 ENGINEERED ANTI-IL-2 ANTIBODIES
AMIT INBAR, OFRAN YANAY, FISCHMAN SHARON, WYANT TIMOTHY, NIMROD GUY, SASSON YEHEZKEL, ZHENIN MICHAEL, LEVITIN NATALIA, GROSSMAN NOAM, BLUVSHTEIN YERMOLAEV OLGA, BARAK FUCHS REUT, LEVIN ITAY, STRAJBL MAREK
Year of Publication 01.02.2024
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Year of Publication 01.02.2024
Patent
A Salmonella typhimurium-translocated Glycerophospholipid:Cholesterol Acyltransferase Promotes Virulence by Binding to the RhoA Protein Switch Regions
LaRock, Doris L., Brzovic, Peter S., Levin, Itay, Blanc, Marie-Pierre, Miller, Samuel I.
Published in The Journal of biological chemistry (24.08.2012)
Published in The Journal of biological chemistry (24.08.2012)
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Journal Article
조작된 항-IL-2 항체
AMIT INBAR, OFRAN YANAY, FISCHMAN SHARON, WYANT TIMOTHY, NIMROD GUY, SASSON YEHEZKEL, ZHENIN MICHAEL, LEVITIN NATALIA, GROSSMAN NOAM, BLUVSHTEIN YERMOLAEV OLGA, BARAK FUCHS REUT, LEVIN ITAY, STRAJBL MAREK
Year of Publication 25.10.2022
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Year of Publication 25.10.2022
Patent
조작된 이중 결합 항체 및 이의 용도
OFRAN YANAY, FASTMAN YAIR, DEMISHTEIN ALIK, BERNSTEIN SHMUEL, DANIELPUR LIRON, IFRACH MORYA, FISCHMAN SHARON, NIMROD GUY, SHLAMKOVICH TOMER, SHNYDER ALEXEY, MALCHENKO NIKOL, SASSON YEHEZKEL, ZHENIN MICHAEL, CHEN AYELET, GATTEGNO HADAR, GROSSMAN NOAM, BLUVSHTEIN YERMOLAEV OLGA, BARAK FUCHS REUT, LEVIN ITAY, MEIR ITZHAK, STRAJBL MAREK
Year of Publication 06.02.2024
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Year of Publication 06.02.2024
Patent
항-종양 괴사 인자 수용체 (TNFR2) 항체 및 그 용도
BEN MAYOR MAY SOFIA, AMIT INBAR, FASTMAN YAIR, OFRAN YANAY, DEMISHTEIN ALIK, DANIELPUR LIRON, CHOEN ZADA EFRAT, WYANT TIMOTHY, FISCHMAN SHARON, SAMET DOR, NIMROD GUY, BITON NEVET ZUR, SASSON YEHEZKEL, ZHENIN MICHAEL, VANA TAL, OREN NINO, LEVITIN NATALIA, TWITO OSHRAT SHIR, CHEN AYELET, GROSSMAN NOAM, BLUVSHTEIN YERMOLAEV OLGA, BARAK FUCHS REUT, LEVIN ITAY, STRAJBL MAREK
Year of Publication 09.03.2023
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Year of Publication 09.03.2023
Patent
Identification of an unconventional E3 binding surface on the UbcH5A a1/4A Ub conjugate recognized by a pathogenic bacterial E3 ligase
Levin, Itay, Eakin, Catherine, Blanc, Marie-Pierre, Klevit, Rachel E, Miller, Samuel I, Brzovic, Peter S
Published in Proceedings of the National Academy of Sciences - PNAS (01.01.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (01.01.2010)
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Journal Article