Treatment of HCV Infection by Targeting MicroRNA
Janssen, Harry L.A, Reesink, Hendrik W, Lawitz, Eric J, Zeuzem, Stefan, Rodriguez-Torres, Maribel, Patel, Keyur, van der Meer, Adriaan J, Patick, Amy K, Chen, Alice, Zhou, Yi, Persson, Robert, King, Barney D, Kauppinen, Sakari, Levin, Arthur A, Hodges, Michael R
Published in The New England journal of medicine (02.05.2013)
Published in The New England journal of medicine (02.05.2013)
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Antisense‐mediated reduction of proprotein convertase subtilisin/kexin type 9 (PCSK9): a first‐in‐human randomized, placebo‐controlled trial
Poelgeest, Eveline P., Hodges, Michael R., Moerland, Matthijs, Tessier, Yann, Levin, Arthur A., Persson, Robert, Lindholm, Marie W., Dumong Erichsen, Kamille, Ørum, Henrik, Cohen, Adam F., Burggraaf, Jacobus
Published in British journal of clinical pharmacology (01.12.2015)
Published in British journal of clinical pharmacology (01.12.2015)
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Acute Kidney Injury During Therapy With an Antisense Oligonucleotide Directed Against PCSK9
van Poelgeest, Eveline P., MD, Swart, Reinout M., MD, Betjes, Michiel G.H., MD, Moerland, Matthijs, PhD, Weening, Jan J., MD, Tessier, Yann, DVM, Hodges, Michael R., MD, Levin, Arthur A., PhD, Burggraaf, Jacobus, MD, PhD
Published in American journal of kidney diseases (01.10.2013)
Published in American journal of kidney diseases (01.10.2013)
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Cross-species comparison of in vivo PK/PD relationships for second-generation antisense oligonucleotides targeting apolipoprotein B-100
Yu, Rosie Z., Lemonidis, Kristina M., Graham, Mark J., Matson, John E., Crooke, Rosanne M., Tribble, Diane L., Wedel, Mark K., Levin, Arthur A., Geary, Richard S.
Published in Biochemical pharmacology (01.03.2009)
Published in Biochemical pharmacology (01.03.2009)
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Renal uptake and tolerability of a 2′-O-methoxyethyl modified antisense oligonucleotide (ISIS 113715) in monkey
Henry, Scott P, Johnson, Mark, Zanardi, Thomas A, Fey, Robert, Auyeung, Diana, Lappin, Patrick B, Levin, Arthur A
Published in Toxicology (Amsterdam) (15.11.2012)
Published in Toxicology (Amsterdam) (15.11.2012)
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Mechanism of Alternative Complement Pathway Dysregulation by a Phosphorothioate Oligonucleotide in Monkey and Human Serum
Henry, Scott P., Jagels, Mark A., Hugli, Tony E., Manalili, Sheri, Geary, Richard S., Giclas, Patricia C., Levin, Arthur A.
Published in Nucleic acid therapeutics (01.10.2014)
Published in Nucleic acid therapeutics (01.10.2014)
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Novel antisense therapy targeting microRNA-132 in patients with heart failure: results of a first-in-human Phase 1b randomized, double-blind, placebo-controlled study
Täubel, Jörg, Hauke, Wilfried, Rump, Steffen, Viereck, Janika, Batkai, Sandor, Poetzsch, Jenny, Rode, Laura, Weigt, Henning, Genschel, Celina, Lorch, Ulrike, Theek, Carmen, Levin, Arthur A, Bauersachs, Johann, Solomon, Scott D, Thum, Thomas
Published in European heart journal (07.01.2021)
Published in European heart journal (07.01.2021)
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Development of an Ultrasensitive Noncompetitive Hybridization–Ligation Enzyme-Linked Immunosorbent Assay for the Determination of Phosphorothioate Oligodeoxynucleotide in Plasma
Yu, Rosie Z., Baker, Brenda, Chappell, Alfred, Geary, Richard S., Cheung, Ellen, Levin, Arthur A.
Published in Analytical biochemistry (01.05.2002)
Published in Analytical biochemistry (01.05.2002)
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Targeted tissue delivery of RNA therapeutics using antibody–oligonucleotide conjugates (AOCs)
Malecova, Barbora, Burke, Rob S, Cochran, Michael, Hood, Michael D, Johns, Rachel, Kovach, Philip R, Doppalapudi, Venkata R, Erdogan, Gulin, Arias, J Danny, Darimont, Beatrice, Miller, Christopher D, Huang, Hanhua, Geall, Andrew, Younis, Husam S, Levin, Arthur A
Published in Nucleic acids research (07.07.2023)
Published in Nucleic acids research (07.07.2023)
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Restoring Dystrophin Expression in Duchenne Muscular Dystrophy Muscle Progress in Exon Skipping and Stop Codon Read Through
HOFFMAN, Eric P, BRONSON, Abby, LEVIN, Arthur A, TAKEDA, Shin'ichi, YOKOTA, Toshifumi, BAUDY, Andreas R, CONNOR, Edward M
Published in The American journal of pathology (01.07.2011)
Published in The American journal of pathology (01.07.2011)
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Assessing unintended hybridization-induced biological effects of oligonucleotides
Lindow, Morten, Vornlocher, Hans-Peter, Riley, Donald, Kornbrust, Douglas J, Burchard, Julja, Whiteley, Laurence O, Kamens, Joanne, Thompson, James D, Nochur, Saraswathy, Younis, Husam, Bartz, Steven, Parry, Joel, Ferrari, Nicolay, Henry, Scott P, Levin, Arthur A
Published in Nature biotechnology (01.10.2012)
Published in Nature biotechnology (01.10.2012)
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Comparison of pharmacokinetics and tissue disposition of an antisense phosphorothioate oligonucleotide targeting human Ha‐ras mRNA in mouse and monkey
Yu, Rosie Z., Geary, Richard S., Leeds, Janet M., Watanabe, Tanya, Moore, Max, Fitchett, Jon, Matson, John, Burckin, Todd, Templin, Michael V., Levin, Arthur A.
Published in Journal of pharmaceutical sciences (01.02.2001)
Published in Journal of pharmaceutical sciences (01.02.2001)
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