Mcl-1 is critical for survival in a subgroup of non-small-cell lung cancer cell lines
Zhang, H, Guttikonda, S, Roberts, L, Uziel, T, Semizarov, D, Elmore, S W, Leverson, J D, Lam, L T
Published in Oncogene (21.04.2011)
Published in Oncogene (21.04.2011)
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Akt inhibitor A-443654 induces rapid Akt Ser-473 phosphorylation independent of mTORC1 inhibition
HAN, E. K.-H, LEVERSON, J. D, MCGONIGAL, T, SHAH, O. J, WOODS, K. W, HUNTER, T, GIRANDA, V. L, LUO, Y
Published in Oncogene (16.08.2007)
Published in Oncogene (16.08.2007)
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Navitoclax (ABT‐263) and bendamustine ± rituximab induce enhanced killing of non‐Hodgkin's lymphoma tumours in vivo
Ackler, S, Mitten, MJ, Chen, J, Clarin, J, Foster, K, Jin, S, Phillips, DC, Schlessinger, S, Wang, B, Leverson, JD, Boghaert, ER
Published in British journal of pharmacology (01.10.2012)
Published in British journal of pharmacology (01.10.2012)
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RNAi-based screening of the human kinome identifies Akt-cooperating kinases: a new approach to designing efficacious multitargeted kinase inhibitors
MORGAN-LAPPE, S, WOODS, K. W, LI, Q, ANDERSON, M. G, SCHURDAK, M. E, LUO, Y, GIRANDA, V. L, FESIK, S. W, LEVERSON, J. D
Published in Oncogene (02.03.2006)
Published in Oncogene (02.03.2006)
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The Tyrosine Kinase Negative Regulator c-Cbl as a RING-Type, E2-Dependent Ubiquitin-Protein Ligase
Claudio A. P. Joazeiro, Wing, Simon S., Huang, Han-kuei, Leverson, Joel D., Hunter, Tony, Liu, Yun-Cai
Published in Science (American Association for the Advancement of Science) (08.10.1999)
Published in Science (American Association for the Advancement of Science) (08.10.1999)
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The Bcl-2 specific BH3 mimetic ABT-199: a promising targeted therapy for t(11;14) multiple myeloma
Touzeau, C, Dousset, C, Le Gouill, S, Sampath, D, Leverson, J D, Souers, A J, Maïga, S, Béné, M C, Moreau, P, Pellat-Deceunynck, C, Amiot, M
Published in Leukemia (01.01.2014)
Published in Leukemia (01.01.2014)
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Potent and selective small-molecule MCL-1 inhibitors demonstrate on-target cancer cell killing activity as single agents and in combination with ABT-263 (navitoclax)
Leverson, J D, Zhang, H, Chen, J, Tahir, S K, Phillips, D C, Xue, J, Nimmer, P, Jin, S, Smith, M, Xiao, Y, Kovar, P, Tanaka, A, Bruncko, M, Sheppard, G S, Wang, L, Gierke, S, Kategaya, L, Anderson, D J, Wong, C, Eastham-Anderson, J, Ludlam, M J C, Sampath, D, Fairbrother, W J, Wertz, I, Rosenberg, S H, Tse, C, Elmore, S W, Souers, A J
Published in Cell death & disease (01.01.2015)
Published in Cell death & disease (01.01.2015)
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Loss in MCL-1 function sensitizes non-Hodgkin’s lymphoma cell lines to the BCL-2-selective inhibitor venetoclax (ABT-199)
Phillips, D C, Xiao, Y, Lam, L T, Litvinovich, E, Roberts-Rapp, L, Souers, A J, Leverson, J D
Published in Blood cancer journal (New York) (13.11.2015)
Published in Blood cancer journal (New York) (13.11.2015)
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Journal Article
Loss in MCL-1 function sensitizes non-Hodgkin's lymphoma cell lines to the BCL-2-selective inhibitor venetoclax (ABT-199)
Phillips, D C, Xiao, Y, Lam, L T, Litvinovich, E, Roberts-Rapp, L, Souers, A J, Leverson, J D
Published in Blood cancer journal (New York) (01.03.2016)
Published in Blood cancer journal (New York) (01.03.2016)
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The inhibitor of apoptosis, cIAP2, functions as a ubiquitin-protein ligase and promotes in vitro monoubiquitination of caspases 3 and 7
Huang, H k, Joazeiro, C A, Bonfoco, E, Kamada, S, Leverson, J D, Hunter, T
Published in The Journal of biological chemistry (01.09.2000)
Published in The Journal of biological chemistry (01.09.2000)
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The APC11 RING-H2 finger mediates E2-dependent ubiquitination
Leverson, J D, Joazeiro, C A, Page, A M, Huang, H k, Hieter, P, Hunter, T
Published in Molecular biology of the cell (01.07.2000)
Published in Molecular biology of the cell (01.07.2000)
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Pim-1 Kinase and p100 Cooperate to Enhance c-Myb Activity
Leverson, Joel D, Koskinen, Päivi J, Orrico, Frank C, Rainio, Eeva-Marja, Jalkanen, Katriina J, Dash, Ajeeta B, Eisenman, Robert N, Ness, Scott A
Published in Molecular cell (01.10.1998)
Published in Molecular cell (01.10.1998)
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Erratum: Loss in MCL-1 function sensitizes non-Hodgkin’s lymphoma cell lines to the BCL-2-selective inhibitor venetoclax (ABT-199)
Phillips, D C, Xiao, Y, Lam, L T, Litvinovich, E, Roberts-Rapp, L, Souers, A J, Leverson, J D
Published in Blood cancer journal (New York) (11.03.2016)
Published in Blood cancer journal (New York) (11.03.2016)
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Functional analysis of human microtubule-based motor proteins, the kinesins and dyneins, in mitosis/cytokinesis using RNA interference
Zhu, Changjun, Zhao, Jian, Bibikova, Marina, Leverson, Joel D, Bossy-Wetzel, Ella, Fan, Jian-Bing, Abraham, Robert T, Jiang, Wei
Published in Molecular biology of the cell (01.07.2005)
Published in Molecular biology of the cell (01.07.2005)
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Small interfering RNA-mediated polo-like kinase 1 depletion preferentially reduces the survival of p53-defective, oncogenic transformed cells and inhibits tumor growth in animals
RAN GUAN, TAPANG, Paul, LEVERSON, Joel D, ALBERT, Daniel, GIRANDA, Vincent L, YAN LUO
Published in Cancer research (Chicago, Ill.) (01.04.2005)
Published in Cancer research (Chicago, Ill.) (01.04.2005)
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Potent and selective inhibitors of Akt kinases slow the progress of tumors in vivo
Luo, Yan, Shoemaker, Alexander R, Liu, Xuesong, Woods, Keith W, Thomas, Sheela A, de Jong, Ron, Han, Edward K, Li, Tongmei, Stoll, Vincent S, Powlas, Jessica A, Oleksijew, Anatol, Mitten, Michael J, Shi, Yan, Guan, Ran, McGonigal, Thomas P, Klinghofer, Vered, Johnson, Eric F, Leverson, Joel D, Bouska, Jennifer J, Mamo, Mulugeta, Smith, Richard A, Gramling-Evans, Emily E, Zinker, Bradley A, Mika, Amanda K, Nguyen, Phong T, Oltersdorf, Tilman, Rosenberg, Saul H, Li, Qun, Giranda, Vincent L
Published in Molecular cancer therapeutics (01.06.2005)
Published in Molecular cancer therapeutics (01.06.2005)
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The Schizosaccharomyces pombe aurora-related kinase Ark1 interacts with the inner centromere protein Pic1 and mediates chromosome segregation and cytokinesis
Leverson, Joel D, Huang, Han-kuei, Forsburg, Susan L, Hunter, Tony
Published in Molecular biology of the cell (01.04.2002)
Published in Molecular biology of the cell (01.04.2002)
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Suppressors of Bir1p (Survivin) Identify Roles for the Chromosomal Passenger Protein Pic1p (INCENP) and the Replication Initiation Factor Psf2p in Chromosome Segregation
Huang, Han-Kuei, Bailis, Julie M., Leverson, Joel D., Gómez, Eliana B., Forsburg, Susan L., Hunter, Tony
Published in Molecular and Cellular Biology (01.10.2005)
Published in Molecular and Cellular Biology (01.10.2005)
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