Identification and characterization of extrachromosomal circular DNA in maternal plasma
Sin, Sarah T. K., Jiang, Peiyong, Deng, Jiaen, Ji, Lu, Cheng, Suk Hang, Dutta, Anindya, Leung, Tak Y., Chan, K. C. Allen, Chiu, Rossa W. K., Lo, Y. M. Dennis
Published in Proceedings of the National Academy of Sciences - PNAS (21.01.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (21.01.2020)
Get full text
Journal Article
Plasma DNA tissue mapping by genome-wide methylation sequencing for noninvasive prenatal, cancer, and transplantation assessments
Sun, Kun, Jiang, Peiyong, Chan, K. C. Allen, Wong, John, Cheng, Yvonne K. Y., Liang, Raymond H. S., Chan, Wai-kong, Ma, Edmond S. K., Chan, Stephen L., Cheng, Suk Hang, Chan, Rebecca W. Y., Tong, Yu K., Ng, Simon S. M., Wong, Raymond S. M., Hui, David S. C., Leung, Tse Ngong, Leung, Tak Y., Lai, Paul B. S., Chiu, Rossa W. K., Lo, Yuk Ming Dennis
Published in Proceedings of the National Academy of Sciences - PNAS (06.10.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (06.10.2015)
Get full text
Journal Article
Genome-wide detection of cytosine methylation by single molecule real-time sequencing
Tse, O Y Olivia, Jiang, Peiyong, Cheng, Suk Hang, Peng, Wenlei, Shang, Huimin, Wong, John, Chan, Stephen L, Poon, Liona C Y, Leung, Tak Y, Chan, K C Allen, Chiu, Rossa W K, Lo, Y M Dennis
Published in Proceedings of the National Academy of Sciences - PNAS (02.02.2021)
Published in Proceedings of the National Academy of Sciences - PNAS (02.02.2021)
Get full text
Journal Article
Size-tagged preferred ends in maternal plasma DNA shed light on the production mechanism and show utility in noninvasive prenatal testing
Sun, Kun, Jiang, Peiyong, Wong, Ada I. C., Cheng, Yvonne K. Y., Cheng, Suk Hang, Zhang, Haiqiang, Chan, K. C. Allen, Leung, Tak Y., Chiu, Rossa W. K., Lo, Y. M. Dennis
Published in Proceedings of the National Academy of Sciences - PNAS (29.05.2018)
Published in Proceedings of the National Academy of Sciences - PNAS (29.05.2018)
Get full text
Journal Article
Orientation-aware plasma cell-free DNA fragmentation analysis in open chromatin regions informs tissue of origin
Sun, Kun, Jiang, Peiyong, Cheng, Suk Hang, Cheng, Timothy H T, Wong, John, Wong, Vincent W S, Ng, Simon S M, Ma, Brigette B Y, Leung, Tak Y, Chan, Stephen L, Mok, Tony S K, Lai, Paul B S, Chan, Henry L Y, Sun, Hao, Chan, K C Allen, Chiu, Rossa W K, Lo, Y M Dennis
Published in Genome research (01.03.2019)
Published in Genome research (01.03.2019)
Get full text
Journal Article
Maternal plasma DNA sequencing reveals the genome-wide genetic and mutational profile of the fetus
Lo, Y M Dennis, Chan, K C Allen, Sun, Hao, Chen, Eric Z, Jiang, Peiyong, Lun, Fiona M F, Zheng, Yama W, Leung, Tak Y, Lau, Tze K, Cantor, Charles R, Chiu, Rossa W K
Published in Science translational medicine (08.12.2010)
Published in Science translational medicine (08.12.2010)
Get more information
Journal Article
Size-based molecular diagnostics using plasma DNA for noninvasive prenatal testing
Yu, Stephanie C. Y., Chan, K. C. Allen, Zheng, Yama W. L., Jiang, Peiyong, Liao, Gary J. W., Sun, Hao, Akolekar, Ranjit, Leung, Tak Y., Go, Attie T. J. I., van Vugt, John M. G., Minekawa, Ryoko, Oudejans, Cees B. M., Nicolaides, Kypros H., Chiu, Rossa W. K., Lo, Y. M. Dennis
Published in Proceedings of the National Academy of Sciences - PNAS (10.06.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (10.06.2014)
Get full text
Journal Article
High-resolution profiling of fetal DNA clearance from maternal plasma by massively parallel sequencing
Yu, Stephanie C Y, Lee, Shara W Y, Jiang, Peiyong, Leung, Tak Y, Chan, K C Allen, Chiu, Rossa W K, Lo, Y M Dennis
Published in Clinical chemistry (Baltimore, Md.) (01.08.2013)
Published in Clinical chemistry (Baltimore, Md.) (01.08.2013)
Get full text
Journal Article
Noninvasive prenatal diagnosis of fetal chromosomal aneuploidy by massively parallel genomic sequencing of DNA in maternal plasma
Chiu, Rossa W.K, Chan, K.C. Allen, Gao, Yuan, Lau, Virginia Y.M, Zheng, Wenli, Leung, Tak Y, Foo, Chris H.F, Xie, Bin, Tsui, Nancy B.Y, Lun, Fiona M.F, Zee, Benny C.Y, Lau, Tze K, Cantor, Charles R, Lo, Y.M. Dennis
Published in Proceedings of the National Academy of Sciences - PNAS (23.12.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (23.12.2008)
Get full text
Journal Article
Noninvasive prenatal methylomic analysis by genomewide bisulfite sequencing of maternal plasma DNA
Lun, Fiona M F, Chiu, Rossa W K, Sun, Kun, Leung, Tak Y, Jiang, Peiyong, Chan, K C Allen, Sun, Hao, Lo, Y M Dennis
Published in Clinical chemistry (Baltimore, Md.) (01.11.2013)
Published in Clinical chemistry (Baltimore, Md.) (01.11.2013)
Get full text
Journal Article
Maternal plasma fetal DNA fractions in pregnancies with low and high risks for fetal chromosomal aneuploidies
Hudecova, Irena, Sahota, Daljit, Heung, Macy M S, Jin, Yongjie, Lee, Wing S, Leung, Tak Y, Lo, Yuk Ming Dennis, Chiu, Rossa W K
Published in PloS one (28.02.2014)
Published in PloS one (28.02.2014)
Get full text
Journal Article
Bradycardia‐to‐delivery interval and fetal outcomes in umbilical cord prolapse
Wong, Lo, Tse, Wing T., Lai, Chit Y., Hui, Annie S. Y., Chaemsaithong, Piya, Sahota, Daljit S., Poon, Liona C., Leung, Tak Y.
Published in Acta obstetricia et gynecologica Scandinavica (01.01.2021)
Published in Acta obstetricia et gynecologica Scandinavica (01.01.2021)
Get full text
Journal Article
Cell-free DNA in maternal plasma and serum: A comparison of quantity, quality and tissue origin using genomic and epigenomic approaches
Wong, Felix C.K., Sun, Kun, Jiang, Peiyong, Cheng, Yvonne K.Y., Chan, K.C. Allen, Leung, Tak Y., Chiu, Rossa W.K., Lo, Yuk Ming Dennis
Published in Clinical biochemistry (01.12.2016)
Published in Clinical biochemistry (01.12.2016)
Get full text
Journal Article
Noninvasive Prenatal Diagnosis of Monogenic Diseases by Digital Size Selection and Relative Mutation Dosage on DNA in Maternal Plasma
Lun, Fiona M. F., Tsui, Nancy B. Y., Chan, K. C. Allen, Leung, Tak Y., Lau, Tze K., Charoenkwan, Pimlak, Chow, Katherine C. K., Lo, Wyatt Y. W., Wanapirak, Chanane, Sanguansermsri, Torpong, Cantor, Charles R., Chiu, Rossa W. K., Lo, Y. M. Dennis
Published in Proceedings of the National Academy of Sciences - PNAS (16.12.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (16.12.2008)
Get full text
Journal Article
Digital PCR for the molecular detection of fetal chromosomal aneuploidy
Lo, Y.M. Dennis, Lun, Fiona M.F, Chan, K.C. Allen, Tsui, Nancy B.Y, Chong, Ka C, Lau, Tze K, Leung, Tak Y, Zee, Benny C.Y, Cantor, Charles R, Chiu, Rossa W.K
Published in Proceedings of the National Academy of Sciences - PNAS (07.08.2007)
Published in Proceedings of the National Academy of Sciences - PNAS (07.08.2007)
Get full text
Journal Article
High resolution size analysis of fetal DNA in the urine of pregnant women by paired-end massively parallel sequencing
Tsui, Nancy B Y, Jiang, Peiyong, Chow, Katherine C K, Su, Xiaoxi, Leung, Tak Y, Sun, Hao, Chan, K C Allen, Chiu, Rossa W K, Lo, Y M Dennis
Published in PloS one (31.10.2012)
Published in PloS one (31.10.2012)
Get full text
Journal Article
Noninvasive prenatal molecular karyotyping from maternal plasma
Yu, Stephanie C Y, Jiang, Peiyong, Choy, Kwong W, Chan, Kwan Chee Allen, Won, Hye-Sung, Leung, Wing C, Lau, Elizabeth T, Tang, Mary H Y, Leung, Tak Y, Lo, Yuk Ming Dennis, Chiu, Rossa W K
Published in PloS one (17.04.2013)
Published in PloS one (17.04.2013)
Get full text
Journal Article
FetalQuant: deducing fractional fetal DNA concentration from massively parallel sequencing of DNA in maternal plasma
PEIYONG JIANG, CHAN, K. C. Allen, LIAO, Gary J. W, ZHENG, Yama W. L, LEUNG, Tak Y, CHIU, Rossa W. K, DENNIS LO, Yuk Ming, HAO SUN
Published in Bioinformatics (15.11.2012)
Published in Bioinformatics (15.11.2012)
Get full text
Journal Article
Applications of genetic-epigenetic tissue mapping for plasma DNA in prenatal testing, transplantation and oncology
Gai, Wanxia, Zhou, Ze, Agbor-Enoh, Sean, Fan, Xiaodan, Lian, Sheng, Jiang, Peiyong, Cheng, Suk Hang, Wong, John, Chan, Stephen L, Jang, Moon Kyoo, Yang, Yanqin, Liang, Raymond Hs, Chan, Wai Kong, Ma, Edmond Sk, Leung, Tak Y, Chiu, Rossa Wk, Valantine, Hannah, Chan, Kc Allen, Lo, Ym Dennis
Published in eLife (23.03.2021)
Published in eLife (23.03.2021)
Get full text
Journal Article
Noninvasive prenatal diagnosis of fetal trisomy 21 by allelic ratio analysis using targeted massively parallel sequencing of maternal plasma DNA
Liao, Gary J W, Chan, K C Allen, Jiang, Peiyong, Sun, Hao, Leung, Tak Y, Chiu, Rossa W K, Lo, Y M Dennis
Published in PloS one (29.05.2012)
Published in PloS one (29.05.2012)
Get full text
Journal Article