Progress and challenges in the study of α6-containing nicotinic acetylcholine receptors
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Conference Proceeding
TC-8831, a nicotinic acetylcholine receptor agonist, reduces l-DOPA-induced dyskinesia in the MPTP macaque
Johnston, Tom H., Huot, Philippe, Fox, Susan H., Koprich, James B., Szeliga, Kendall T., James, John W., Graef, John D., Letchworth, Sharon R., Jordan, Kristen G., Hill, Michael P., Brotchie, Jonathan M.
Published in Neuropharmacology (01.10.2013)
Published in Neuropharmacology (01.10.2013)
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Comparison of acetylcholine receptor interactions of the marine toxins, 13-desmethylspirolide C and gymnodimine
Hauser, Terry A., Hepler, Christopher D., Kombo, David C., Grinevich, Vladimir P., Kiser, Melanie N., Hooker, Dawn N., Zhang, Jiahui, Mountfort, Douglas, Selwood, Andrew, Akireddy, S. Rao, Letchworth, Sharon R., Yohannes, Daniel
Published in Neuropharmacology (01.06.2012)
Published in Neuropharmacology (01.06.2012)
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Systemic Administration of an Alpha-7 Nicotinic Acetylcholine Agonist Reverses Neuropathic Pain in Male Sprague Dawley Rats
Loram, Lisa C, Taylor, Frederick R, Strand, Keith A, Maier, Steven F, Speake, Jason D, Jordan, Kristen G, James, John W, Wene, Steven P, Pritchard, Robert C, Green, Heather, Van Dyke, Katherine, Mazarov, Anatoly, Letchworth, Sharon R, Watkins, Linda R
Published in The journal of pain (01.12.2012)
Published in The journal of pain (01.12.2012)
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Long-lasting cognitive improvement with nicotinic receptor agonists: mechanisms of pharmacokinetic-pharmacodynamic discordance
Buccafusco, Jerry J, Letchworth, Sharon R, Bencherif, Merouane, Lippiello, Patrick M
Published in Trends in pharmacological sciences (Regular ed.) (01.07.2005)
Published in Trends in pharmacological sciences (Regular ed.) (01.07.2005)
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Progression of Changes in Dopamine Transporter Binding Site Density as a Result of Cocaine Self-Administration in Rhesus Monkeys
Letchworth, Sharon R, Nader, Michael A, Smith, Hilary R, Friedman, David P, Porrino, Linda J
Published in The Journal of neuroscience (15.04.2001)
Published in The Journal of neuroscience (15.04.2001)
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Analgesic effects mediated by neuronal nicotinic acetylcholine receptor agonists: Correlation with desensitization of α4β2 receptors
Zhang, Jiahui, Xiao, Yun-De, Jordan, Kristen G., Hammond, Phil S., Van Dyke, Katherine M., Mazurov, Anatoly A., Speake, Jason D., Lippiello, Patrick M., James, John W., Letchworth, Sharon R., Bencherif, Merouane, Hauser, Terry A.
Published in European journal of pharmaceutical sciences (18.12.2012)
Published in European journal of pharmaceutical sciences (18.12.2012)
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Synthesis of a [2- Pyridinyl- 18F]-labelled fluoro derivative of (−)-Cytisine as a candidate radioligand for brain nicotinic α4β2 receptor imaging with PET
Roger, Gaëlle, Lagnel, Béatrice, Rouden, Jacques, Besret, Laurent, Valette, Héric, Demphel, Stéphane, Gopisetti, JaganMohan, Coulon, Christine, Ottaviani, Michele, Wrenn, Lori A, Letchworth, Sharon R, Bohme, Georg A, Benavides, Jesus, Lasne, Marie-Claire, Bottlaender, Michel, Dollé, Frédéric
Published in Bioorganic & medicinal chemistry (01.12.2003)
Published in Bioorganic & medicinal chemistry (01.12.2003)
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Pharmacological characterization of Endomorphin-1 and Endomorphin-2 in Mouse Brain
Goldberg, I E, Rossi, G C, Letchworth, S R, Mathis, J P, Ryan-Moro, J, Leventhal, L, Su, W, Emmel, D, Bolan, E A, Pasternak, G W
Published in The Journal of pharmacology and experimental therapeutics (01.08.1998)
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Published in The Journal of pharmacology and experimental therapeutics (01.08.1998)
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In vitro and in vivo characterization of TC-1827, a novel brain α4β2 nicotinic receptor agonist with pro-cognitive activity
Bohme, Georg Andrees, Letchworth, Sharon R., Piot-Grosjean, Odile, Gatto, Gregory J., Obinu, Marie-Carmen, Caldwell, William S., Laville, Michel, Brunel, Pascale, Pellerin, Rachel, Leconte, Jean-Pierre, Genevois-Borella, Arielle, Dubedat, Pierre, Mazadier, Martine, Pradier, Laurent, Bencherif, Merouane, Benavides, Jesus
Published in Drug development research (01.05.2004)
Published in Drug development research (01.05.2004)
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Effects of chronic cocaine administration on dopamine transporter mRNA and protein in the rat
Letchworth, Sharon R, Daunais, James B, Hedgecock, Ashlee A, Porrino, Linda J
Published in Brain research (07.03.1997)
Published in Brain research (07.03.1997)
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alpha 4 beta 2 nicotinic receptors play a role in the nAChR-mediated decline in l-dopa-induced dyskinesias in parkinsonian rats
Quik, Maryka, Campos, Carla, Bordia, Tanuja, Strachan, Jon-Paul, Zhang, Jenny, McIntosh, JMichael, Letchworth, Sharon, Jordan, Kristen
Published in Neuropharmacology (01.08.2013)
Published in Neuropharmacology (01.08.2013)
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Nicotinic receptor agonists reduce L-DOPA-induced dyskinesias in a monkey model of Parkinson's disease
Zhang, Danhui, Mallela, Archana, Sohn, David, Carroll, F Ivy, Bencherif, Merouane, Letchworth, Sharon, Quik, Maryka
Published in The Journal of pharmacology and experimental therapeutics (01.10.2013)
Published in The Journal of pharmacology and experimental therapeutics (01.10.2013)
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Journal Article
α4β2 nicotinic receptors play a role in the nAChR-mediated decline in l-dopa-induced dyskinesias in parkinsonian rats
Quik, Maryka, Campos, Carla, Bordia, Tanuja, Strachan, Jon-Paul, Zhang, Jenny, McIntosh, J. Michael, Letchworth, Sharon, Jordan, Kristen
Published in Neuropharmacology (01.08.2013)
Published in Neuropharmacology (01.08.2013)
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Neuronal nicotinic receptor agonists ameliorate spontaneous motor asymmetries and motor discoordination in a unilateral mouse model of Parkinson's disease
Kucinski, Aaron, Wersinger, Scott, Stachowiak, Ewa K., Corso, Thomas D., Parry, Matthew J., Zhang, Jenny, Jordan, Kristen, Letchworth, Sharon, Bencherif, Merouane, Stachowiak, Michal K.
Published in Pharmacology, biochemistry and behavior (01.10.2013)
Published in Pharmacology, biochemistry and behavior (01.10.2013)
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TC‐1734: An Orally Active Neuronal Nicotinic Acetylcholine Receptor Modulator with Antidepressant, Neuroprotective and Long‐Lasting Cognitive Effects
Gatto, Gregory J., Bohme, G Andrees, Caldwell, William S., Letchworth, Sharon R., Traina, Vincent M., Obinu, M. Carmen, Laville, Michel, Reibaud, Michel, Pradier, Laurent, Dunbar, Geoffrey, Bencherif, Merouane
Published in CNS drug reviews (01.06.2004)
Published in CNS drug reviews (01.06.2004)
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Autoradiographic localization of125I[Tyr14]orphanin FQ/nociceptin and125I[Tyr10]orphanin FQ/nociceptin(1-11) binding sites in rat brain
Letchworth, Sharon R., Mathis, John P., Rossi, Grace C., Bodnar, Richard J., Pasternak, Gavril W.
Published in Journal of comparative neurology (1911) (24.07.2000)
Published in Journal of comparative neurology (1911) (24.07.2000)
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Ispronicline: A Novel α4β2 Nicotinic Acetylcholine Receptor-Selective Agonist With Cognition-Enhancing and Neuroprotective Properties
Lippiello, Patrick, Letchworth, Sharon R., Gatto, Gregory J., Traina, Vincent M., Bencherif, Merouane
Published in Journal of molecular neuroscience (01.09.2006)
Published in Journal of molecular neuroscience (01.09.2006)
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