Cyclic GMP potentiation by WIN 58237, a novel cyclic nucleotide phosphodiesterase inhibitor
Silver, P J, Dundore, R L, Bode, D C, de Garavilla, L, Buchholz, R A, van Aller, G, Hamel, L T, Bacon, E, Singh, B, Lesher, G Y
Published in The Journal of pharmacology and experimental therapeutics (01.12.1994)
Get full text
Published in The Journal of pharmacology and experimental therapeutics (01.12.1994)
Journal Article
Cardiotonic Activity of Amrinone–Win 40680 [5-Amino-3,4f-bipyridin-6(lH)-one]
ALOUSI, ADAWIA A, FARAH, ALFRED E, LESHER, GEORGE Y, OPALKA, CHESTER J
Published in Circulation research (01.11.1979)
Published in Circulation research (01.11.1979)
Get full text
Journal Article
Novel and Potent Adenosine 3',5'-Cyclic Phosphate Phosphodiesterase III Inhibitors: Thiazolo[4,5-b][1,6]naphthyridin-2-ones
Singh, Baldev, Bacon, Edward R, Lesher, George Y, Robinson, Shaughnessy, Pennock, Patrick O, Bode, Donald C, Pagani, Edward D, Bentley, Ross G, Connell, Mary J, Hamel, Linda T, Silver, Paul J
Published in Journal of medicinal chemistry (01.07.1995)
Published in Journal of medicinal chemistry (01.07.1995)
Get full text
Journal Article
Novel cAMP PDE III inhibitors: imidazo[4,5-b]pyridin-2(3H)-ones and thiazolo[4,5-b]pyridin-2(3H)-ones and their analogs
Singh, Baldev, Bacon, Edward R, Robinson, Shaughnessy, Fritz, Richard K, Lesher, George Y, Kumar, Virendra, Dority, John A, Reuman, Michael, Kuo, Gee Hong
Published in Journal of medicinal chemistry (01.01.1994)
Published in Journal of medicinal chemistry (01.01.1994)
Get full text
Journal Article
Novel cAMP PDE III inhibitors: 1,6-naphthyridin-2(1H)-ones
Singh, Baldev, Lesher, George Y, Pluncket, Kevin C, Pagani, Edward D, Bode, Donald C, Bentley, Ross G, Connell, Mary J, Hamel, Linda T, Silver, Paul J
Published in Journal of medicinal chemistry (01.12.1992)
Published in Journal of medicinal chemistry (01.12.1992)
Get full text
Journal Article
Mammalian topoisomerase II inhibitory activity of 1-cyclopropyl-6,8-difluoro-1,4-dihydro-7-(2,6-dimethyl-4-pyridinyl)-4-oxo-3-quinolinecarboxylic acid and related derivatives
Wentland, Mark P, Lesher, George Y, Reuman, Michael, Gruett, Monte D, Singh, Baldev, Aldous, Suzanne C, Dorff, Peter H, Rake, James B, Coughlin, Susan A
Published in Journal of medicinal chemistry (01.09.1993)
Published in Journal of medicinal chemistry (01.09.1993)
Get full text
Journal Article
ABSORPTION, EXCRETION, AND METABOLISM OF A NEW ANTIBACTERIAL AGENT, NALIDIXIC ACID
MCCHESNEY, E W, FROELICH, E J, LESHER, G Y, CRAIN, A V, ROSI, D
Published in Toxicology and applied pharmacology (01.05.1964)
Published in Toxicology and applied pharmacology (01.05.1964)
Get more information
Journal Article
Synthesis and Antibacterial Activity of Some Novel 1-Substituted 1,4-Dihydro-4-oxo-7-pyridinyl-3-quinolinecarboxylic Acids. Potent Antistaphylococcal Agents
Reuman, Michael, Daum, Sol J, Singh, Baldev, Wentland, Mark P, Perni, Robert B, Pennock, Patrick, Carabateas, Philip M, Gruett, Monte D, Saindane, Manohar T, Dorff, Peter H, Coughlin, Susan A, Sedlock, David M, Rake, James B, Lesher, George Y
Published in Journal of medicinal chemistry (01.07.1995)
Published in Journal of medicinal chemistry (01.07.1995)
Get full text
Journal Article
Pharmacologic and pharmacodynamic effects of the selective low Km cyclic AMP phosphodiesterase III inhibitors WIN 63291 and WIN 62582
Pagani, E D, Dundore, R L, Bode, D C, Bacon, E R, Singh, B, Lesher, G Y, Buchholz, R A, Silver, P J
Published in Journal of cardiovascular pharmacology (01.09.1994)
Get more information
Published in Journal of cardiovascular pharmacology (01.09.1994)
Journal Article
Species-dependent pharmacodynamic effects of the selective low Km cyclic AMP phosphodiesterase III inhibitors WIN 58993 and WIN 62005
Dundore, R L, Pagani, E D, Bode, D C, Bacon, E R, Singh, B, Lesher, G Y, Buchholz, R A, Silver, P J
Published in Journal of cardiovascular pharmacology (01.01.1995)
Published in Journal of cardiovascular pharmacology (01.01.1995)
Get more information
Journal Article
Intramolecular Hydrogen Bonding in 7-Chloro-4-diethylaminoethylaminoquinoline
Nachod, F. C, Surrey, A. R, Lesher, G. Y, Martini, C. M, Mayer, J. R, Priznar, M, Webb, W. G
Published in Journal of the American Chemical Society (01.06.1959)
Published in Journal of the American Chemical Society (01.06.1959)
Get full text
Journal Article
Relationship of structure of bridged (2,6-dimethyl-4-pyridinyl)quinolones to mammalian topoisomerase II inhibition
Wentland, Mark P., Lesher, George Y., Reuman, Michael, Pilling, Garry M., Saindane, Manohar T., Perni, Robert B., Eissenstat, Michael A., Weaver, John D., Singh, Baldev, Rake, James, Coughlin, Susan A.
Published in Bioorganic & medicinal chemistry letters (01.08.1993)
Published in Bioorganic & medicinal chemistry letters (01.08.1993)
Get full text
Journal Article
Novel orally active inhibitors of passive cutaneous anaphylaxis in rats: N-[2-(4-Pyridinyl)-4-pyrimidinyl] ureas and dialkyl [[[2-(4-pyridinyl)-4-pyrimidinyl]amino]methylene]malonates
Lesher, George Y, Singh, Baldev, Mielens, Zigurd
Published in Journal of medicinal chemistry (01.07.1982)
Published in Journal of medicinal chemistry (01.07.1982)
Get full text
Journal Article
Mammalian topoisomerase II inhibitory activity of 1-cyclopropyl-6,8- difluoro-1,4-dihydro-7-(2,6-dimethyl-4-pyridinyl)-4-oxo-3-quinolinecarb oxylic acid and related derivatives
Wentland, M P, Lesher, G Y, Reuman, M, Gruett, M D, Singh, B, Aldous, S C, Dorff, P H, Rake, J B, Coughlin, S A
Published in Journal of medicinal chemistry (17.09.1993)
Get full text
Published in Journal of medicinal chemistry (17.09.1993)
Journal Article