Crystal Structure of the Ectodomain Complex of the CGRP Receptor, a Class-B GPCR, Reveals the Site of Drug Antagonism
ter Haar, Ernst, Koth, Christopher M., Abdul-Manan, Norzehan, Swenson, Lora, Coll, Joyce T., Lippke, Judith A., Lepre, Christopher A., Garcia-Guzman, Miguel, Moore, Jonathan M.
Published in Structure (London) (01.09.2010)
Published in Structure (London) (01.09.2010)
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Refolding and Characterization of a Soluble Ectodomain Complex of the Calcitonin Gene-Related Peptide Receptor
Koth, Christopher M, Abdul-Manan, Norzehan, Lepre, Christopher A, Connolly, Peter J, Yoo, Sanghee, Mohanty, Arun K, Lippke, Judith A, Zwahlen, Jacque, Coll, Joyce T, Doran, John D, Garcia-Guzman, Miguel, Moore, Jonathan M
Published in Biochemistry (Easton) (09.03.2010)
Published in Biochemistry (Easton) (09.03.2010)
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Nuclear magnetic resonance-based approaches for lead generation in drug discovery
Peng, J W, Lepre, C A, Fejzo, J, Abdul-Manan, N, Moore, J M
Published in Methods in enzymology (01.01.2001)
Published in Methods in enzymology (01.01.2001)
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Crystal Structure of the Hepatitis C Virus NS3 Protease Domain Complexed with a Synthetic NS4A Cofactor Peptide
Kim, J.L, Morgenstern, K.A, Lin, C, Fox, T, Dwyer, M.D, Landro, J.A, Chambers, S.P, Markland, W, Lepre, C.A, O'Malley, E.T, Harbeson, S.L, Rice, C.M, Murcko, M.A, Caron, P.R, Thomson, J.A
Published in Cell (18.10.1996)
Published in Cell (18.10.1996)
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Fragment-Based Discovery of Dual JC Virus and BK Virus Helicase Inhibitors
Bonafoux, Dominique, Nanthakumar, Suganthini, Bandarage, Upul K, Memmott, Christine, Lowe, Derek, Aronov, Alex M, Bhisetti, Govinda Rao, Bonanno, Kenneth C, Coll, Joyce, Leeman, Joshua, Lepre, Christopher A, Lu, Fan, Perola, Emanuele, Rijnbrand, Rene, Taylor, William P, Wilson, Dean, Zhou, Yi, Zwahlen, Jacque, ter Haar, Ernst
Published in Journal of medicinal chemistry (11.08.2016)
Published in Journal of medicinal chemistry (11.08.2016)
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Applications of SHAPES screening in drug discovery
Lepre, Christopher A, Peng, Jeffrey, Fejzo, Jasna, Abdul-Manan, Norzehan, Pocas, Jennifer, Jacobs, Marc, Xie, Xiaoling, Moore, Jonathan M
Published in Combinatorial chemistry & high throughput screening (01.12.2002)
Published in Combinatorial chemistry & high throughput screening (01.12.2002)
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High-resolution solution structure of reduced French bean plastocyanin and comparison with the crystal structure of poplar plastocyanin
Moore, Jonathan M., Lepre, Christopher A., Gippert, Garry P., Chazin, Walter J., Case, David A., Wright, Peter E.
Published in Journal of molecular biology (20.09.1991)
Published in Journal of molecular biology (20.09.1991)
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The SHAPES strategy: an NMR-based approach for lead generation in drug discovery
Fejzo, Jasna, Lepre, Christopher A, Peng, Jeffrey W, Bemis, Guy W, Ajay, Murcko, Mark A, Moore, Jonathan M
Published in Chemistry & biology (01.10.1999)
Published in Chemistry & biology (01.10.1999)
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Synthesis and characterization of trans-[Pt(NH3)2Cl2] adducts of d(CCTCGAGTCTCC)•d(GGAGACTCGAGG)
LEPRE, C. A, CHASSOT, L, COSTELLO, C. E, LIPPARD, S. J
Published in Biochemistry (Easton) (23.01.1990)
Published in Biochemistry (Easton) (23.01.1990)
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Dynamic NMR studies of ligand‐receptor interactions: Design and analysis of a rapidly exchanging complex of FKBP‐12/FK506 with a 24 kDa calcineurin fragment
Fejzo, Jasna, Lepre, Christopher A., Peng, Jeffrey W., Su, Michael S.‐S., Thomson, John A., Moore, Jonathan M.
Published in Protein science (01.09.1996)
Published in Protein science (01.09.1996)
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Solution Structure of FK506 Bound to the R42K, H87V Double Mutant of FKBP-12
Lepre, Christopher A, Pearlman, David A, Cheng, Jya-Wei, DeCenzo, Maureen T, Moore, Jonathan M, Livingston, David J
Published in Biochemistry (Easton) (01.11.1994)
Published in Biochemistry (Easton) (01.11.1994)
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