Animal models in the pharmacokinetic/pharmacodynamic evaluation of antimicrobial agents
Zhao, Miao, Lepak, Alexander J., Andes, David R.
Published in Bioorganic & medicinal chemistry (15.12.2016)
Published in Bioorganic & medicinal chemistry (15.12.2016)
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Journal Article
Isavuconazole (BAL4815) Pharmacodynamic Target Determination in an In Vivo Murine Model of Invasive Pulmonary Aspergillosis against Wild-Type and cyp51 Mutant Isolates of Aspergillus fumigatus
LEPAK, Alexander J, MARCHILLO, Karen, VANHECKER, Jamie, ANDES, David R
Published in Antimicrobial Agents and Chemotherapy (01.12.2013)
Published in Antimicrobial Agents and Chemotherapy (01.12.2013)
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Journal Article
Posaconazole Pharmacodynamic Target Determination against Wild-Type and Cyp51 Mutant Isolates of Aspergillus fumigatus in an In Vivo Model of Invasive Pulmonary Aspergillosis
LEPAK, Alexander J, MARCHILLO, Karen, VANHECKER, Jaimie, ANDES, David R
Published in Antimicrobial Agents and Chemotherapy (01.01.2013)
Published in Antimicrobial Agents and Chemotherapy (01.01.2013)
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Journal Article
Impact of Triazole Therapeutic Drug Monitoring Availability and Timing
McCreary, Erin K, Bayless, Meg, Van, Ahn P, Lepak, Alexander J, Wiebe, Donald A, Schulz, Lucas T, Andes, David R
Published in Antimicrobial agents and chemotherapy (01.10.2019)
Published in Antimicrobial agents and chemotherapy (01.10.2019)
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Journal Article
Time Course Global Gene Expression Analysis of an In Vivo Candida Biofilm
Nett, Jeniel E., Lepak, Alexander J., Marchillo, Karen, Andes, David R.
Published in The Journal of infectious diseases (15.07.2009)
Published in The Journal of infectious diseases (15.07.2009)
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Journal Article
Isavuconazole Pharmacodynamic Target Determination for Candida Species in an In Vivo Murine Disseminated Candidiasis Model
LEPAK, Alexander J, MARCHILLO, Karen, VANHECKER, Jamie, DIEKEMA, Daniel, ANDES, David R
Published in Antimicrobial Agents and Chemotherapy (01.11.2013)
Published in Antimicrobial Agents and Chemotherapy (01.11.2013)
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Journal Article
Diagnostic and Therapeutic Utility of Positive Intravascular Catheter Tip Cultures
Ulrich, Patrizia, Lepak, Alexander J, Chen, Derrick J
Published in Microbiology spectrum (21.12.2022)
Published in Microbiology spectrum (21.12.2022)
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Journal Article
FDA Public Workshop Summary: Advancing Animal Models for Antibacterial Drug Development
Byrne, James M, Waack, Ursula, Weinstein, Edward A, Joshi, Abhay, Shurland, Simone M, Iarikov, Dmitri, Bulitta, Jürgen B, Diep, Binh An, Guina, Tina, Hope, William W, Lawrenz, Matthew B, Lepak, Alexander J, Luna, Brian M, Miesel, Lynn, Phipps, Andrew J, Walsh, Thomas J, Weiss, William, Amini, Thushi, Farley, John J
Published in Antimicrobial agents and chemotherapy (16.12.2020)
Published in Antimicrobial agents and chemotherapy (16.12.2020)
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Journal Article
Impact of In Vivo Triazole and Echinocandin Combination Therapy for Invasive Pulmonary Aspergillosis: Enhanced Efficacy against Cyp51 Mutant Isolates
LEPAK, Alexander J, MARCHILLO, Karen, VANHECKER, Jamie, ANDES, David R
Published in Antimicrobial Agents and Chemotherapy (01.11.2013)
Published in Antimicrobial Agents and Chemotherapy (01.11.2013)
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Journal Article
Comparative Pharmacodynamics of the New Oxazolidinone Tedizolid Phosphate and Linezolid in a Neutropenic Murine Staphylococcus aureus Pneumonia Model
LEPAK, Alexander J, MARCHILLO, Karen, PICHEREAU, Solen, CRAIG, William A, ANDES, David R
Published in Antimicrobial Agents and Chemotherapy (01.11.2012)
Published in Antimicrobial Agents and Chemotherapy (01.11.2012)
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Journal Article
Clinical Pharmacodynamic Index Identification for Micafungin in Esophageal Candidiasis: Dosing Strategy Optimization
ANDES, David R, REYNOLDS, Daniel K, VAN WART, Scott A, LEPAK, Alexander J, KOVANDA, Laura L, BHAVNANI, Sujata M
Published in Antimicrobial Agents and Chemotherapy (01.11.2013)
Published in Antimicrobial Agents and Chemotherapy (01.11.2013)
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Journal Article
Validated Preclinical Mouse Model for Therapeutic Testing against Multidrug-Resistant Pseudomonas aeruginosa Strains
Warawa, Jonathan M, Duan, Xiaoxian, Anderson, Charles D, Sotsky, Julie B, Cramer, Daniel E, Pfeffer, Tia L, Guo, Haixun, Adcock, Scott, Lepak, Alexander J, Andes, David R, Slone, Stacey A, Stromberg, Arnold J, Gabbard, Jon D, Severson, William E, Lawrenz, Matthew B
Published in Microbiology spectrum (26.10.2022)
Published in Microbiology spectrum (26.10.2022)
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Journal Article
In Vivo Pharmacodynamic Evaluation of Omadacycline (PTK 0796) against Streptococcus pneumoniae in the Murine Pneumonia Model
Lepak, Alexander J, Zhao, Miao, Marchillo, Karen, VanHecker, Jamie, Andes, David R
Published in Antimicrobial agents and chemotherapy (01.05.2017)
Published in Antimicrobial agents and chemotherapy (01.05.2017)
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Journal Article
WCK 5222 (Cefepime/Zidebactam) Pharmacodynamic Target Analysis against Metallo-β-lactamase producing Enterobacteriaceae in the Neutropenic Mouse Pneumonia Model
Lepak, Alexander J, Zhao, Miao, Andes, David R
Published in Antimicrobial agents and chemotherapy (01.12.2019)
Published in Antimicrobial agents and chemotherapy (01.12.2019)
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Journal Article
Pharmacodynamic Optimization for Treatment of Invasive Candida auris Infection
Lepak, Alexander J, Zhao, Miao, Berkow, Elizabeth L, Lockhart, Shawn R, Andes, David R
Published in Antimicrobial agents and chemotherapy (01.08.2017)
Published in Antimicrobial agents and chemotherapy (01.08.2017)
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Journal Article