Reclassifying Hepatic Cell Death during Liver Damage: Ferroptosis-A Novel Form of Non-Apoptotic Cell Death?
Macías-Rodríguez, Ricardo U, Inzaugarat, María Eugenia, Ruiz-Margáin, Astrid, Nelson, Leonard J, Trautwein, Christian, Cubero, Francisco Javier
Published in International journal of molecular sciences (28.02.2020)
Published in International journal of molecular sciences (28.02.2020)
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Journal Article
Advanced preclinical models for evaluation of drug-induced liver injury – consensus statement by the European Drug-Induced Liver Injury Network [PRO-EURO-DILI-NET]
Fernandez-Checa, Jose C., Bagnaninchi, Pierre, Ye, Hui, Sancho-Bru, Pau, Falcon-Perez, Juan M., Royo, Felix, Garcia-Ruiz, Carmen, Konu, Ozlen, Miranda, Joana, Lunov, Oleg, Dejneka, Alexandr, Elfick, Alistair, McDonald, Alison, Sullivan, Gareth J., Aithal, Guruprasad P., Lucena, M. Isabel, Andrade, Raul J., Fromenty, Bernard, Kranendonk, Michel, Cubero, Francisco Javier, Nelson, Leonard J.
Published in Journal of hepatology (01.10.2021)
Published in Journal of hepatology (01.10.2021)
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Journal Article
Dual Targeting of G9a and DNA Methyltransferase‐1 for the Treatment of Experimental Cholangiocarcinoma
Colyn, Leticia, Bárcena‐Varela, Marina, Álvarez‐Sola, Gloria, Latasa, M. Ujue, Uriarte, Iker, Santamaría, Eva, Herranz, Jose M., Santos‐Laso, Alvaro, Arechederra, Maria, Ruiz de Gauna, Mikel, Aspichueta, Patricia, Canale, Matteo, Casadei‐Gardini, Andrea, Francesconi, Maria, Carotti, Simone, Morini, Sergio, Nelson, Leonard J., Iraburu, Maria J., Chen, Chaobo, Sangro, Bruno, Marin, Jose J.G., Martinez‐Chantar, Maria L., Banales, Jesus M., Arnes‐Benito, Robert, Huch, Meritxell, Patino, John M., Dar, Altaf A., Nosrati, Mehdi, Oyarzábal, Julen, Prósper, Felipe, Urman, Jesus, Cubero, Francisco Javier, Trautwein, Christian, Berasain, Carmen, Fernandez‐Barrena, Maite G., Avila, Matias A.
Published in Hepatology (Baltimore, Md.) (01.06.2021)
Published in Hepatology (Baltimore, Md.) (01.06.2021)
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Journal Article
Mitogen-Activated Protein Kinases (MAPKs) and Cholangiocarcinoma: The Missing Link
Chen, Chaobo, Nelson, Leonard J, Ávila, Matías A, Cubero, Francisco Javier
Published in Cells (Basel, Switzerland) (28.09.2019)
Published in Cells (Basel, Switzerland) (28.09.2019)
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Journal Article
Genetic and pharmacological inhibition of XBP1 protects against APAP hepatotoxicity through the activation of autophagy
Ye, Hui, Chen, Chaobo, Wu, Hanghang, Zheng, Kang, Martín-Adrados, Beatriz, Caparros, Esther, Francés, Rubén, Nelson, Leonard J., Gómez del Moral, Manuel, Asensio, Iris, Vaquero, Javier, Bañares, Rafael, Ávila, Matías A., Andrade, Raúl J., Isabel Lucena, M., Martínez-Chantar, Maria Luz, Reeves, Helen L., Masson, Steven, Blumberg, Richard S., Gracia-Sancho, Jordi, Nevzorova, Yulia A., Martínez-Naves, Eduardo, Cubero, Francisco Javier
Published in Cell death & disease (10.02.2022)
Published in Cell death & disease (10.02.2022)
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Journal Article
Fibrotic Events in the Progression of Cholestatic Liver Disease
Wu, Hanghang, Chen, Chaobo, Ziani, Siham, Nelson, Leonard J., Ávila, Matías A., Nevzorova, Yulia A., Cubero, Francisco Javier
Published in Cells (Basel, Switzerland) (05.05.2021)
Published in Cells (Basel, Switzerland) (05.05.2021)
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Journal Article
Acetaminophen cytotoxicity is ameliorated in a human liver organotypic co-culture model
Nelson, Leonard J., Navarro, Maria, Treskes, Philipp, Samuel, Kay, Tura-Ceide, Olga, Morley, Steven D., Hayes, Peter C., Plevris, John N.
Published in Scientific reports (03.12.2015)
Published in Scientific reports (03.12.2015)
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Journal Article
New molecular mechanisms in cholangiocarcinoma: signals triggering interleukin-6 production in tumor cells and KRAS co-opted epigenetic mediators driving metabolic reprogramming
Colyn, Leticia, Alvarez-Sola, Gloria, Latasa, M Ujue, Uriarte, Iker, Herranz, Jose M, Arechederra, Maria, Vlachogiannis, George, Rae, Colin, Pineda-Lucena, Antonio, Casadei-Gardini, Andrea, Pedica, Federica, Aldrighetti, Luca, López-López, Angeles, López-Gonzálvez, Angeles, Barbas, Coral, Ciordia, Sergio, Van Liempd, Sebastiaan M, Falcón-Pérez, Juan M, Urman, Jesus, Sangro, Bruno, Vicent, Silve, Iraburu, Maria J, Prosper, Felipe, Nelson, Leonard J, Banales, Jesus M, Martinez-Chantar, Maria Luz, Marin, Jose J G, Braconi, Chiara, Trautwein, Christian, Corrales, Fernando J, Cubero, F Javier, Berasain, Carmen, Fernandez-Barrena, Maite G, Avila, Matias A
Published in Journal of experimental & clinical cancer research (26.05.2022)
Published in Journal of experimental & clinical cancer research (26.05.2022)
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Journal Article
Krüppel-like factor 6 is a transcriptional activator of autophagy in acute liver injury
Sydor, Svenja, Manka, Paul, Best, Jan, Jafoui, Sami, Sowa, Jan-Peter, Zoubek, Miguel Eugenio, Hernandez-Gea, Virginia, Cubero, Francisco Javier, Kälsch, Julia, Vetter, Diana, Fiel, Maria Isabel, Hoshida, Yujin, Bian, C. Billie, Nelson, Leonard J., Moshage, Han, Faber, Klaas Nico, Paul, Andreas, Baba, Hideo A., Gerken, Guido, Friedman, Scott L., Canbay, Ali, Bechmann, Lars P.
Published in Scientific reports (14.08.2017)
Published in Scientific reports (14.08.2017)
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Journal Article
Damages Caps in Medical Malpractice Cases
NELSON III, LEONARD J., MORRISEY, MICHAEL A., KILGORE, MEREDITH L.
Published in The Milbank quarterly (01.06.2007)
Published in The Milbank quarterly (01.06.2007)
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Journal Article
Alcoholic liver disease: Utility of animal models
Lamas-Paz, Arantza, Hao, Fengjie, Nelson, Leonard J, Vázquez, Maria Teresa, Canals, Santiago, Gómez Del Moral, Manuel, Martínez-Naves, Eduardo, Nevzorova, Yulia A, Cubero, Francisco Javier
Published in World journal of gastroenterology : WJG (07.12.2018)
Published in World journal of gastroenterology : WJG (07.12.2018)
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Journal Article
Development of an invasively monitored porcine model of acetaminophen-induced acute liver failure
Newsome, Philip N, Henderson, Neil C, Nelson, Leonard J, Dabos, Costas, Filippi, Celine, Bellamy, Chris, Howie, Forbes, Clutton, Richard E, King, Tim, Lee, Alistair, Hayes, Peter C, Plevris, John N
Published in BMC gastroenterology (30.03.2010)
Published in BMC gastroenterology (30.03.2010)
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Journal Article
Next-generation sequencing of bile cell-free DNA for the early detection of patients with malignant biliary strictures
Arechederra, Maria, Rullán, María, Amat, Irene, Oyon, Daniel, Zabalza, Lucia, Elizalde, Maria, Latasa, M Ujue, Mercado, Maria R, Ruiz-Clavijo, David, Saldaña, Cristina, Fernández-Urién, Ignacio, Carrascosa, Juan, Jusué, Vanesa, Guerrero-Setas, David, Zazpe, Cruz, González-Borja, Iranzu, Sangro, Bruno, Herranz, Jose M, Purroy, Ana, Gil, Isabel, Nelson, Leonard J, Vila, Juan J, Krawczyk, Marcin, Zieniewicz, Krzysztof, Patkowski, Waldemar, Milkiewicz, Piotr, Cubero, Francisco Javier, Alkorta-Aranburu, Gorka, G Fernandez-Barrena, Maite, Urman, Jesus M, Berasain, Carmen, Avila, Matias A
Published in Gut (01.06.2022)
Published in Gut (01.06.2022)
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Journal Article
Control compounds for preclinical drug-induced liver injury assessment: Consensus-driven systematic review by the ProEuroDILI network
Segovia-Zafra, Antonio, Villanueva-Paz, Marina, Serras, Ana Sofia, Matilla-Cabello, Gonzalo, Bodoque-García, Ana, Di Zeo-Sánchez, Daniel E., Niu, Hao, Álvarez-Álvarez, Ismael, Sanz-Villanueva, Laura, Godec, Sergej, Milisav, Irina, Bagnaninchi, Pierre, Andrade, Raúl J., Lucena, M Isabel, Fernández-Checa, José C., Cubero, Francisco Javier, Miranda, Joana Paiva, Nelson, Leonard J.
Published in Journal of hepatology (01.10.2024)
Published in Journal of hepatology (01.10.2024)
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Journal Article
Human Hepatic HepaRG Cells Maintain an Organotypic Phenotype with High Intrinsic CYP450 Activity/Metabolism and Significantly Outperform Standard HepG2/C3A Cells for Pharmaceutical and Therapeutic Applications
Nelson, Leonard J., Morgan, Katie, Treskes, Philipp, Samuel, Kay, Henderson, Catherine J., LeBled, Claire, Homer, Natalie, Grant, M. Helen, Hayes, Peter C., Plevris, John N.
Published in Basic & clinical pharmacology & toxicology (01.01.2017)
Published in Basic & clinical pharmacology & toxicology (01.01.2017)
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Journal Article
Non-invasive methods of monitoring Fe3O4 magnetic nanoparticle toxicity in human liver HepaRG cells using impedance biosensing and Coherent anti-Stokes Raman spectroscopic (CARS) microscopy
Kuhn, Joel, McDonald, Alison, Mongoin, Cyril, Anderson, Graham, Lafeuillade, Guillemette, Mitchell, Stephen, Elfick, Alistair P.D., Bagnaninchi, Pierre O., Yiu, Humphrey H.P., Nelson, Leonard J.
Published in Toxicology letters (01.04.2024)
Published in Toxicology letters (01.04.2024)
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Journal Article
Lack of Cyclin E1 in hepatocytes aggravates ethanol-induced liver injury and hepatic steatosis in experimental murine model of acute and chronic alcohol-associated liver disease
Ramadori, Pierluigi, Woitok, Marius Maximilian, Estévez-Vázquez, Olga, Benedé-Ubieto, Raquel, Leal-Lassalle, Hector, Lamas-Paz, Arantza, Guo, Feifei, Fabre, Jeanne, Otto, Julia, Verwaayen, Anna, Reissing, Johanna, Bruns, Tony, Erschfeld, Stephanie, Haas, Ute, Paffen, Daniela, Nelson, Leonard J., Vaquero, Javier, Bañares, Rafael, Trautwein, Christian, Cubero, Francisco Javier, Liedtke, Christian, Nevzorova, Yulia A.
Published in Biochimica et biophysica acta. Molecular basis of disease (01.04.2023)
Published in Biochimica et biophysica acta. Molecular basis of disease (01.04.2023)
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Journal Article
Tort Law and Medical Malpractice Insurance Premiums
Kilgore, Meredith L., Morrisey, Michael A., Nelson, Leonard J.
Published in Inquiry (Chicago) (01.10.2006)
Published in Inquiry (Chicago) (01.10.2006)
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Journal Article
Malpractice Verdicts and Changing Birthing Practices
Bronstein, Janet M., Nelson, Leonard J.
Published in Journal of midwifery & women's health (01.07.2018)
Published in Journal of midwifery & women's health (01.07.2018)
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Journal Article