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PI3K pathway activation mediates resistance to MEK inhibitors in KRAS mutant cancers
Wee, Susan, Jagani, Zainab, Xiang, Kay Xiaoqin, Loo, Alice, Dorsch, Marion, Yao, Yung-Mae, Sellers, William R, Lengauer, Christoph, Stegmeier, Frank
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Robust Activity of Avapritinib, Potent and Highly Selective Inhibitor of Mutated KIT, in Patient-derived Xenograft Models of Gastrointestinal Stromal Tumors
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Inhibitory effects of midostaurin and avapritinib on myeloid progenitors derived from patients with KIT D816V positive advanced systemic mastocytosis
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Single-vector inducible lentiviral RNAi system for oncology target validation
Wiederschain, Dmitri, Susan, Wee, Chen, Lin, Loo, Alice, Yang, Guizhi, Huang, Alan, Chen, Yan, Caponigro, Giordano, Yao, Yung-mae, Lengauer, Christoph, Sellers, William R., Benson, John D.
Published in Cell cycle (Georgetown, Tex.) (01.02.2009)
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Barber, Thomas D, McManus, Kirk, Yuen, Karen W.Y, Reis, Marcelo, Parmigiani, Giovanni, Shen, Dong, Barrett, Irene, Nouhi, Yasaman, Spencer, Forrest, Markowitz, Sanford, Velculescu, Victor E, Kinzler, Kenneth W, Vogelstein, Bert, Lengauer, Christoph, Hieter, Philip
Published in Proceedings of the National Academy of Sciences - PNAS (04.03.2008)
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Crystal structure of human CDK4 in complex with a D-type cyclin
Day, Philip J, Cleasby, Anne, Tickle, Ian J, O'Reilly, Marc, Coyle, Joe E, Holding, Finn P, McMenamin, Rachel L, Yon, Jeff, Chopra, Rajiv, Lengauer, Christoph, Jhoti, Harren
Published in Proceedings of the National Academy of Sciences - PNAS (17.03.2009)
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The significance of unstable chromosomes in colorectal cancer
Lengauer, Christoph, Rajagopalan, Harith, Nowak, Martin A, Vogelstein, Bert
Published in Nature reviews. Cancer (01.09.2003)
Published in Nature reviews. Cancer (01.09.2003)
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Lengauer, Christoph, Rajagopalan, Harith, Jallepalli, Prasad V, Rago, Carlo, Velculescu, Victor E, Kinzler, Kenneth W, Vogelstein, Bert
Published in Nature (04.03.2004)
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An Evolutionary Approach for Identifying Driver Mutations in Colorectal Cancer
Foo, Jasmine, Liu, Lin L, Leder, Kevin, Riester, Markus, Iwasa, Yoh, Lengauer, Christoph, Michor, Franziska
Published in PLoS computational biology (01.09.2015)
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Lengauer, Christoph, Peters, Brock A, Diaz, Luis A, Polyak, Kornelia, Meszler, Leslie, Romans, Kathy, Guinan, Eva C, Antin, Joseph H, Myerson, David, Hamilton, Stanley R, Vogelstein, Bert, Kinzler, Kenneth W
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Published in Nature (London) (04.04.2002)
Published in Nature (London) (04.04.2002)
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The Role of Chromosomal Instability in Tumor Initiation
Nowak, Martin A., Komarova, Natalia L., Sengupta, Anirvan, Jallepalli, Prasad V., Shih, le-Ming, Vogelstein, Bert, Lengauer, Christoph
Published in Proceedings of the National Academy of Sciences - PNAS (10.12.2002)
Published in Proceedings of the National Academy of Sciences - PNAS (10.12.2002)
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Genes Expressed in Human Tumor Endothelium
St. Croix, Brad, Rago, Carlo, Velculescu, Victor, Traverso, Giovanni, Romans, Katharine E., Montgomery, Elizabeth, Lal, Anita, Riggins, Gregory J., Lengauer, Christoph, Vogelstein, Bert, Kinzler, Kenneth W.
Published in Science (American Association for the Advancement of Science) (18.08.2000)
Published in Science (American Association for the Advancement of Science) (18.08.2000)
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Disruption of p53 in human cancer cells alters the responses to therapeutic agents
Bunz, F, Hwang, P M, Torrance, C, Waldman, T, Zhang, Y, Dillehay, L, Williams, J, Lengauer, C, Kinzler, K W, Vogelstein, B
Published in The Journal of clinical investigation (01.08.1999)
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Published in Cancer research (Chicago, Ill.) (01.07.2010)
Published in Cancer research (Chicago, Ill.) (01.07.2010)
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RAF/RAS oncogenes and mismatch-repair status
Rajagopalan, Harith, Bardelli, Alberto, Lengauer, Christoph, Kinzler, Kenneth W., Vogelstein, Bert, Velculescu, Victor E.
Published in Nature (London) (01.08.2002)
Published in Nature (London) (01.08.2002)
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