Granulocyte-Monocyte Progenitors and Monocyte-Dendritic Cell Progenitors Independently Produce Functionally Distinct Monocytes
Yáñez, Alberto, Coetzee, Simon G., Olsson, Andre, Muench, David E., Berman, Benjamin P., Hazelett, Dennis J., Salomonis, Nathan, Grimes, H. Leighton, Goodridge, Helen S.
Published in Immunity (Cambridge, Mass.) (21.11.2017)
Published in Immunity (Cambridge, Mass.) (21.11.2017)
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The Human Cell Atlas bone marrow single-cell interactive web portal
Hay, Stuart B., Ferchen, Kyle, Chetal, Kashish, Grimes, H. Leighton, Salomonis, Nathan
Published in Experimental hematology (01.12.2018)
Published in Experimental hematology (01.12.2018)
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Asymmetrically Segregated Mitochondria Provide Cellular Memory of Hematopoietic Stem Cell Replicative History and Drive HSC Attrition
Hinge, Ashwini, He, Jingyi, Bartram, James, Javier, Jose, Xu, Juying, Fjellman, Ellen, Sesaki, Hiromi, Li, Tingyu, Yu, Jie, Wunderlich, Mark, Mulloy, James, Kofron, Matthew, Salomonis, Nathan, Grimes, H. Leighton, Filippi, Marie-Dominique
Published in Cell stem cell (05.03.2020)
Published in Cell stem cell (05.03.2020)
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Combinatorial Single-Cell Analyses of Granulocyte-Monocyte Progenitor Heterogeneity Reveals an Early Uni-potent Neutrophil Progenitor
Kwok, Immanuel, Becht, Etienne, Xia, Yu, Ng, Melissa, Teh, Ye Chean, Tan, Leonard, Evrard, Maximilien, Li, Jackson L.Y., Tran, Hoa T.N., Tan, Yingrou, Liu, Dehua, Mishra, Archita, Liong, Ka Hang, Leong, Keith, Zhang, Yuning, Olsson, Andre, Mantri, Chinmay Kumar, Shyamsunder, Pavithra, Liu, Zhaoyuan, Piot, Cecile, Dutertre, Charles-Antoine, Cheng, Hui, Bari, Sudipto, Ang, Nicholas, Biswas, Subhra K., Koeffler, H. Philip, Tey, Hong Liang, Larbi, Anis, Su, I-Hsin, Lee, Bernett, St. John, Ashley, Chan, Jerry K.Y., Hwang, William Y.K., Chen, Jinmiao, Salomonis, Nathan, Chong, Shu Zhen, Grimes, H. Leighton, Liu, Bing, Hidalgo, Andrés, Newell, Evan W., Cheng, Tao, Ginhoux, Florent, Ng, Lai Guan
Published in Immunity (Cambridge, Mass.) (18.08.2020)
Published in Immunity (Cambridge, Mass.) (18.08.2020)
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DoubletDecon: Deconvoluting Doublets from Single-Cell RNA-Sequencing Data
DePasquale, Erica A.K., Schnell, Daniel J., Van Camp, Pieter-Jan, Valiente-Alandí, Íñigo, Blaxall, Burns C., Grimes, H. Leighton, Singh, Harinder, Salomonis, Nathan
Published in Cell reports (Cambridge) (05.11.2019)
Published in Cell reports (Cambridge) (05.11.2019)
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Obesity alters the long-term fitness of the hematopoietic stem cell compartment through modulation of Gfi1 expression
Lee, Jung-Mi, Govindarajah, Vinothini, Goddard, Bryan, Hinge, Ashwini, Muench, David E, Filippi, Marie-Dominique, Aronow, Bruce, Cancelas, Jose A, Salomonis, Nathan, Grimes, H Leighton, Reynaud, Damien
Published in The Journal of experimental medicine (05.02.2018)
Published in The Journal of experimental medicine (05.02.2018)
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Lsd1 as a therapeutic target in Gfi1-activated medulloblastoma
Lee, Catherine, Rudneva, Vasilisa A., Erkek, Serap, Zapatka, Marc, Chau, Lianne Q., Tacheva-Grigorova, Silvia K., Garancher, Alexandra, Rusert, Jessica M., Aksoy, Ozlem, Lea, Robin, Mohammad, Helai P., Wang, Jianxun, Weiss, William A., Grimes, H. Leighton, Pfister, Stefan M., Northcott, Paul A., Wechsler-Reya, Robert J.
Published in Nature communications (18.01.2019)
Published in Nature communications (18.01.2019)
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cellHarmony: cell-level matching and holistic comparison of single-cell transcriptomes
DePasquale, Erica A K, Schnell, Daniel, Dexheimer, Phillip, Ferchen, Kyle, Hay, Stuart, Chetal, Kashish, Valiente-Alandí, Íñigo, Blaxall, Burns C, Grimes, H Leighton, Salomonis, Nathan
Published in Nucleic acids research (02.12.2019)
Published in Nucleic acids research (02.12.2019)
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MAPK-negative feedback regulation confers dependence to JAK2V617F signaling
Kesarwani, Meenu, Kincaid, Zachary, Azhar, Mohammad, Menke, Jacob, Schwieterman, Joshua, Ansari, Sekhu, Reaves, Angela, Deininger, Michael E., Levine, Ross, Grimes, H. Leighton, Azam, Mohammad
Published in Leukemia (01.08.2023)
Published in Leukemia (01.08.2023)
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The Molecular Signature of Megakaryocyte-Erythroid Progenitors Reveals a Role for the Cell Cycle in Fate Specification
Lu, Yi-Chien, Sanada, Chad, Xavier-Ferrucio, Juliana, Wang, Lin, Zhang, Ping-Xia, Grimes, H. Leighton, Venkatasubramanian, Meenakshi, Chetal, Kashish, Aronow, Bruce, Salomonis, Nathan, Krause, Diane S.
Published in Cell reports (Cambridge) (20.11.2018)
Published in Cell reports (Cambridge) (20.11.2018)
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A primer on single-cell genomics in myeloid biology
Ferchen, Kyle, Song, Baobao, Leighton Grimes, H
Published in Current opinion in hematology (01.01.2021)
Published in Current opinion in hematology (01.01.2021)
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Targeting c-FOS and DUSP1 abrogates intrinsic resistance to tyrosine-kinase inhibitor therapy in BCR-ABL-induced leukemia
Kesarwani, Meenu, Kincaid, Zachary, Gomaa, Ahmed, Huber, Erika, Rohrabaugh, Sara, Siddiqui, Zain, Bouso, Muhammad F, Latif, Tahir, Xu, Ming, Komurov, Kakajan, Mulloy, James C, Cancelas, Jose A, Grimes, H Leighton, Azam, Mohammad
Published in Nature medicine (01.04.2017)
Published in Nature medicine (01.04.2017)
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Meis1 preserves hematopoietic stem cells in mice by limiting oxidative stress
Unnisa, Zeenath, Clark, Jason P., Roychoudhury, Jayeeta, Thomas, Elizabeth, Tessarollo, Lino, Copeland, Neal G., Jenkins, Nancy A., Grimes, H. Leighton, Kumar, Ashish R.
Published in Blood (13.12.2012)
Published in Blood (13.12.2012)
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Transcription factor RUNX1 promotes survival of acute myeloid leukemia cells
Goyama, Susumu, Schibler, Janet, Cunningham, Lea, Zhang, Yue, Rao, Yalan, Nishimoto, Nahoko, Nakagawa, Masahiro, Olsson, Andre, Wunderlich, Mark, Link, Kevin A, Mizukawa, Benjamin, Grimes, H Leighton, Kurokawa, Mineo, Liu, P Paul, Huang, Gang, Mulloy, James C
Published in The Journal of clinical investigation (01.09.2013)
Published in The Journal of clinical investigation (01.09.2013)
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A calcium- and calpain-dependent pathway determines the response to lenalidomide in myelodysplastic syndromes
Fang, Jing, Liu, Xiaona, Bolanos, Lyndsey, Barker, Brenden, Rigolino, Carmela, Cortelezzi, Agostino, Oliva, Esther N, Cuzzola, Maria, Grimes, H Leighton, Fontanillo, Celia, Komurov, Kakajan, MacBeth, Kyle, Starczynowski, Daniel T
Published in Nature medicine (01.07.2016)
Published in Nature medicine (01.07.2016)
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